hydroxyphenytoin has been researched along with omeprazole in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gugler, R; Jensen, JC | 1 |
| Amamoto, T; Higuchi, S; Ieiri, I; Irie, S; Kimura, M; Kubota, T; Mamiya, K; Nakamura, K; Nakano, S; Tashiro, N; Urae, A; Wada, Y; Yoshioka, S | 1 |
| Li, XY; Li, YP; Liu, YN; Yang, YZ; Yuan, M; Zhu, JB | 1 |
1 trial(s) available for hydroxyphenytoin and omeprazole
| Article | Year |
|---|---|
Stereoselective 4'-hydroxylation of phenytoin: relationship to (S)-mephenytoin polymorphism in Japanese.
Topics: Administration, Oral; Alleles; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Gene Expression Regulation, Enzymologic; Genotype; Homozygote; Humans; Hydroxylation; Japan; Mixed Function Oxygenases; Omeprazole; Phenotype; Phenytoin; Polymerase Chain Reaction; Polymorphism, Genetic; Stereoisomerism; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases | 1997 |
2 other study(ies) available for hydroxyphenytoin and omeprazole
| Article | Year |
|---|---|
Omeprazole inhibits oxidative drug metabolism. Studies with diazepam and phenytoin in vivo and 7-ethoxycoumarin in vitro.
Topics: Adult; Benzimidazoles; Coumarins; Diazepam; Drug Interactions; Humans; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Nordazepam; Omeprazole; Oxidation-Reduction; Phenytoin | 1985 |
[Effect of high altitude hypoxia on the activity and protein expression of CYP2C9 and CYP2C19].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Altitude; Animals; Cytochrome P-450 Enzyme System; Enzyme Activation; Female; Hypoxia; Male; Omeprazole; Phenytoin; Rats; Rats, Sprague-Dawley | 2012 |