hydroxymethyltolbutamide has been researched along with carboxytolbutamide in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (27.27) | 18.7374 |
| 1990's | 7 (63.64) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boutagy, JS; Page, MA; Shenfield, GM | 1 |
| Birkett, DJ; Gregov, D; Miners, JO; Randles, D; Veronese, ME | 1 |
| Adir, J; Miller, AK; Vestal, RE | 1 |
| Belanger, PM; St-Hilaire, S | 1 |
| Keal, J; Somogyi, A; Stockley, C | 1 |
| Albasini, A; Manenti, F; Melegari, M; Pecorari, P; Vampa, G | 1 |
| Makaya, O; Nakamura, J; Nishida, K; Sasaki, H; Shibasaki, J; Washio, K | 1 |
| Birkett, DJ; Miners, JO; Rees, DL; Veronese, ME | 1 |
| Bridge, S; Gross, AS; Shenfield, GM | 1 |
| Brøsen, K; Hansen, LL | 1 |
| Brockmöller, J; Fuhr, U; Hering, U; Jabrane, W; Jakob, V; Jetter, A; Kasel, D; Kinzig-Schippers, M; Kirchheiner, J; Lazar, A; Rodamer, M; Skott, A; Sörgel, F; Tomalik-Scharte, D; Walchner-Bonjean, M | 1 |
1 trial(s) available for hydroxymethyltolbutamide and carboxytolbutamide
| Article | Year |
|---|---|
Pharmacokinetics of tolbutamide in ethnic Chinese.
Topics: Adult; Asian People; Chromatography, High Pressure Liquid; Female; Humans; Male; Tolbutamide; White People | 1999 |
10 other study(ies) available for hydroxymethyltolbutamide and carboxytolbutamide
| Article | Year |
|---|---|
A screening test for slow metabolisers of tolbutamide.
Topics: Adolescent; Adult; Chromatography, High Pressure Liquid; Female; Half-Life; Humans; Male; Middle Aged; Pilot Projects; Polymorphism, Genetic; Reference Values; Tolbutamide | 1991 |
Validation of the tolbutamide metabolic ratio for population screening with use of sulfaphenazole to produce model phenotypic poor metabolizers.
Topics: Administration, Oral; Adult; Chromatography; Female; Half-Life; Humans; Hydroxylation; Male; Phenotype; Random Allocation; Sulfaphenazole; Tolbutamide | 1990 |
Excretion of tolbutamide metabolites in young and old subjects.
Topics: Adult; Aged; Aged, 80 and over; Aging; Humans; Male; Middle Aged; Tolbutamide | 1990 |
Simultaneous determinations of tolbutamide and its hydroxy and carboxy metabolites in serum and urine: application to pharmacokinetic studies of tolbutamide in the rat.
Topics: Animals; Chromatography, High Pressure Liquid; Injections, Intraperitoneal; Injections, Intravenous; Liver; Male; Rats; Rats, Inbred Strains; Tolbutamide | 1989 |
Simultaneous determination of tolbutamide and its hydroxy and carboxy metabolites in plasma and urine by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Tolbutamide | 1986 |
An HPLC method for the simultaneous determination of tolbutamide and its metabolites in plasma.
Topics: Chromatography, High Pressure Liquid; Humans; Tolbutamide | 1981 |
A new aspect of tolbutamide metabolism in the rabbit: the role of 1-butyl-3-(p-formylphenyl)sulphonylurea.
Topics: Animals; Chromatography, High Pressure Liquid; Disulfiram; Male; Oxidation-Reduction; Rabbits; Tolbutamide | 1993 |
Tolbutamide hydroxylation in humans: lack of bimodality in 106 healthy subjects.
Topics: Adolescent; Adult; Female; Humans; Hydroxylation; Male; Metabolic Clearance Rate; Middle Aged; Tolbutamide | 1993 |
Quantitative determination of tolbutamide and its metabolites in human plasma and urine by high-performance liquid chromatography and UV detection.
Topics: Chromatography, High Pressure Liquid; Humans; Hypoglycemic Agents; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tolbutamide | 1999 |
Cytochrome P450 2C9 phenotyping using low-dose tolbutamide.
Topics: Administration, Oral; Adult; Aryl Hydrocarbon Hydroxylases; Chromatography, Liquid; Cross-Over Studies; Cytochrome P-450 CYP2C9; Dose-Response Relationship, Drug; Exons; Genotype; Humans; Male; Mass Spectrometry; Metabolic Clearance Rate; Middle Aged; Pharmacogenetics; Phenotype; Pilot Projects; Sequence Analysis, DNA; Time Factors; Tolbutamide | 2004 |