hydroxymethylbilane has been researched along with uroporphyrinogen iii in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (18.18) | 18.7374 |
| 1990's | 9 (40.91) | 18.2507 |
| 2000's | 2 (9.09) | 29.6817 |
| 2010's | 6 (27.27) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Baxter, RL; Boyd, AS; Davies, RC; Evans, JN; Ichinose, I; Mackenzie, NE; Scott, AI | 1 |
| Bishop, DF; Desnick, RJ; Tsai, SF | 1 |
| Battersby, AR; Fookes, CJ; Matcham, GW; McDonald, E | 1 |
| Berry, A; Jordan, PM | 1 |
| Urata, G | 1 |
| Atshaves, BP; Pichon, C; Scott, AI; Stolowich, NJ | 1 |
| Bonner, WM; Ivanova, VS; Popescu, N; Zimonjic, D | 1 |
| Awan, SJ; Shoolingin-Jordan, PM; Warren, MJ | 2 |
| Blundell, TL; Brownlie, PD; Cooper, JB; Hädener, A; Lambert, R; Louie, GV; Malashkevich, VN; Shoolingin-Jordan, PM; Warren, MJ; Wood, SP | 1 |
| Awan, SJ; Shoolingin-Jordan, PM; Siligardi, G; Warren, MJ | 1 |
| Leadbeater, R; Shoolingin-Jordan, PM | 1 |
| Ando, M; Hanioka, N; Jinno, H; Nishimura, T; Onodera, S | 1 |
| Brancaleoni, V; Cappellini, MD; Di Pierro, E | 1 |
| Chu, X; Li, D; Li, N; Liu, X; Wu, L | 1 |
| Badenas, C; Beaumont, C; Clayton, J; de Verneuil, H; Delaby, C; Deybach, JC; Ducamp, S; Ferreira, GC; Ged, C; Gouya, L; Herrero, C; Lyoumi, S; Puy, H; To-Figueras, J | 1 |
| Bulusu, G; Bung, N; Pradhan, M; Srinivasan, H | 1 |
| Györffy, D; Szilágyi, A; Závodszky, P | 1 |
| Chen, M; Funamizu, T; Ishimori, K; Tanaka, Y; Uchida, T | 1 |
| Bernardo-Seisdedos, G; Cooper, JB; Gu, S; Millet, O; Pickersgill, RW; Pluta, P; Rojas, AL; Roversi, P | 1 |
| Fujimoto, K; Hiroyuki, N; Matsuda, R; Motoyama, Y; Murakami, T; Nakagawa, I; Nakai, Y; Nakamura, M; Nakazawa, T; Nishimura, F; Omoto, K; Shida, Y; Tanaka, Y; Tatsumi, Y | 1 |
| Hirabayashi, K; Hisaeda, Y; Iijima, M; Masuko, T; Omata, Y; Sato, H; Sugishima, M; Takano, M; Tsukaguchi, M; Wada, K; Yamamoto, K | 1 |
1 review(s) available for hydroxymethylbilane and uroporphyrinogen iii
| Article | Year |
|---|---|
[The chemistry of porphyrins and their precursors on the heme biosynthetic chain].
Topics: Aminolevulinic Acid; Heme; Humans; Porphobilinogen; Porphyrins; Uroporphyrinogens | 1995 |
21 other study(ies) available for hydroxymethylbilane and uroporphyrinogen iii
| Article | Year |
|---|---|
Biosynthesis of porphyrins and corrins. 1. 1H and 13C NMR spectra of (hydroxymethyl)bilane and uroporphyrinogens I and III.
Topics: Ammonia-Lyases; Chromatography, High Pressure Liquid; Corrinoids; Hydro-Lyases; Hydroxymethylbilane Synthase; Magnetic Resonance Spectroscopy; Porphyrinogens; Porphyrins; Rhodobacter sphaeroides; Uroporphyrinogen III Synthetase; Uroporphyrinogens; Vitamin B 12 | 1986 |
Purification and properties of uroporphyrinogen III synthase from human erythrocytes.
Topics: Amino Acids; Cations; Chromatography; Enzyme Activation; Erythrocytes; Humans; Hydro-Lyases; Hydrogen-Ion Concentration; Isoelectric Focusing; Kinetics; Molecular Weight; Sulfhydryl Reagents; Uroporphyrinogen III Synthetase; Uroporphyrinogens | 1987 |
Biosynthesis of the pigments of life: formation of the macrocycle.
Topics: Ammonia-Lyases; Animals; Chemical Phenomena; Chemistry; Euglena gracilis; Humans; Hydroxymethylbilane Synthase; Isomerases; Porphyrins; Pyrroles; Uroporphyrinogen III Synthetase; Uroporphyrinogens; Vitamin B 12 | 1980 |
Preuroporphyrinogen, a universal intermediate in the biosynthesis of uroporphyrinogen III.
Topics: Animals; Chickens; Erythrocytes; Humans; Isomerases; Porphobilinogen; Porphyrinogens; Reticulocytes; Rhodobacter sphaeroides; Saccharomyces cerevisiae; Species Specificity; Triticum; Uroporphyrinogen III Synthetase; Uroporphyrinogens | 1980 |
Evidence for an intermediate in the enzymatic formation of uroporphyrinogen III.
Topics: Escherichia coli; Genes, Bacterial; Hydrogen-Ion Concentration; In Vitro Techniques; Magnetic Resonance Spectroscopy; Molecular Structure; Recombinant Proteins; Temperature; Uroporphyrinogen III Synthetase; Uroporphyrinogens | 1994 |
Chromosomal localization of the human histone H2A.X gene to 11q23.2-q23.3 by fluorescence in situ hybridization.
Topics: Animals; Base Sequence; Chromosome Mapping; Chromosomes, Human, Pair 11; Cricetinae; Electrophoresis, Agar Gel; HeLa Cells; Histones; Humans; Hybrid Cells; Molecular Sequence Data; Oligonucleotide Probes; RNA, Messenger; Uroporphyrinogens | 1994 |
Discovery that the assembly of the dipyrromethane cofactor of porphobilinogen deaminase holoenzyme proceeds initially by the reaction of preuroporphyrinogen with the apoenzyme.
Topics: Apoenzymes; Coenzymes; Cysteine; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Escherichia coli; Gene Expression; Hydroxymethylbilane Synthase; Molecular Structure; Mutation; Porphobilinogen; Uroporphyrinogens | 1996 |
The three-dimensional structure of Escherichia coli porphobilinogen deaminase at 1.76-A resolution.
Topics: Amino Acid Sequence; Binding Sites; Coenzymes; Conserved Sequence; Crystallization; Crystallography, X-Ray; Escherichia coli; Hydrogen Bonding; Hydroxymethylbilane Synthase; Models, Molecular; Molecular Sequence Data; Porphobilinogen; Protein Conformation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Alignment; Uroporphyrinogens | 1996 |
Discovery of a novel mechanism for cofactor assembly by Escherichia coli porphobilinogen deaminase.
Topics: Apoenzymes; Circular Dichroism; Coenzymes; Escherichia coli; Hydroxymethylbilane Synthase; Kinetics; Protein Conformation; Uroporphyrinogens | 1997 |
Dipyrromethane cofactor assembly of porphobilinogen deaminase: formation of apoenzyme and preparation of holoenzyme.
Topics: Apoenzymes; Coenzymes; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Hydroxymethylbilane Synthase; Levulinic Acids; Molecular Structure; Porphobilinogen; Protein Conformation; Uroporphyrinogens | 1997 |
Coupled assay for uroporphyrinogen III synthase.
Topics: Chromatography, High Pressure Liquid; Escherichia coli; Hydroxymethylbilane Synthase; Molecular Structure; Porphobilinogen; Recombinant Proteins; Spectrometry, Fluorescence; Spectrophotometry; Uroporphyrinogen III Synthetase; Uroporphyrinogens; Uroporphyrins | 1997 |
Irgasan DP 300 (5-chloro-2-(2,4-dichlorophenoxy)-phenol) induces cytochrome P450s and inhibits haem biosynthesis in rat hepatocytes cultured on Matrigel.
Topics: Aminolevulinic Acid; Animals; Anti-Infective Agents, Local; Carbanilides; Cells, Cultured; Chromatography, High Pressure Liquid; Collagen; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Combinations; Enzyme Induction; Extracellular Matrix; Heme; Laminin; Liver; Male; Proteoglycans; Rats; Rats, Wistar; Uroporphyrinogen III Synthetase; Uroporphyrinogens; Uroporphyrins | 1997 |
Gene symbol: HMBS. Disease: Porphyria, acute intermittent.
Topics: Base Sequence; Frameshift Mutation; Gene Deletion; Humans; Porphyria, Acute Intermittent; Uroporphyrinogens | 2005 |
Functional studies of rat hydroxymethylbilane synthase.
Topics: Amino Acid Sequence; Animals; Chromatography, Affinity; Cloning, Molecular; Enzyme Stability; Gene Library; Histidine; Hydrogen-Ion Concentration; Hydroxymethylbilane Synthase; Liver; Molecular Sequence Data; Mutagenesis, Site-Directed; Porphobilinogen; Rats; Sequence Homology, Amino Acid; Substrate Specificity; Temperature; Uroporphyrinogens | 2008 |
ALAS2 acts as a modifier gene in patients with congenital erythropoietic porphyria.
Topics: 5-Aminolevulinate Synthetase; Amino Acid Sequence; Anemia, Sideroblastic; Base Sequence; Child, Preschool; Electrophoresis, Polyacrylamide Gel; Family Health; Female; Genetic Diseases, X-Linked; Genotype; Humans; Infant; Kinetics; Male; Molecular Sequence Data; Mutation, Missense; Pedigree; Porphyria, Erythropoietic; Protoporphyria, Erythropoietic; Sequence Homology, Amino Acid; Severity of Illness Index; Spectrophotometry; Uroporphyrinogen III Synthetase; Uroporphyrinogens | 2011 |
Structural insights into E. coli porphobilinogen deaminase during synthesis and exit of 1-hydroxymethylbilane.
Topics: Catalysis; Catalytic Domain; Computational Biology; Diffusion; Escherichia coli; Heme; Hydroxymethylbilane Synthase; Molecular Conformation; Molecular Dynamics Simulation; Mutation; Pyrroles; Uroporphyrinogens | 2014 |
Segment swapping aided the evolution of enzyme function: The case of uroporphyrinogen III synthase.
Topics: Bacterial Proteins; Biocatalysis; Entropy; Evolution, Molecular; Ligands; Molecular Dynamics Simulation; Motion; Protein Binding; Protein Domains; Protein Structure, Secondary; Thermus thermophilus; Uroporphyrinogen III Synthetase; Uroporphyrinogens | 2017 |
Heme Binding to Porphobilinogen Deaminase from Vibrio cholerae Decelerates the Formation of 1-Hydroxymethylbilane.
Topics: Crystallography, X-Ray; Escherichia coli; Heme; Hydroxymethylbilane Synthase; Protein Binding; Spectrum Analysis, Raman; Uroporphyrinogens; Vibrio cholerae | 2018 |
Structural basis of pyrrole polymerization in human porphobilinogen deaminase.
Topics: Catalysis; Catalytic Domain; Crystallography, X-Ray; Humans; Hydroxymethylbilane Synthase; Polymerization; Porphobilinogen; Protein Conformation; Pyrroles; Uroporphyrinogens | 2018 |
Expression of peptide transporter 1 has a positive correlation in protoporphyrin IX accumulation induced by 5-aminolevulinic acid with photodynamic detection of non-small cell lung cancer and metastatic brain tumor specimens originating from non-small cel
Topics: Aminolevulinic Acid; ATP Binding Cassette Transporter, Subfamily G, Member 2; Blotting, Western; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Ferrochelatase; Heme Oxygenase-1; Humans; Lung Neoplasms; Neoplasm Metastasis; Peptide Transporter 1; Photochemotherapy; Protoporphyrins; Real-Time Polymerase Chain Reaction; Spectrometry, Fluorescence; Uroporphyrinogens | 2019 |
Crystal structures of hydroxymethylbilane synthase complexed with a substrate analog: a single substrate-binding site for four consecutive condensation steps.
Topics: Catalysis; Catalytic Domain; Crystallography, X-Ray; Humans; Hydroxymethylbilane Synthase; Molecular Dynamics Simulation; Porphobilinogen; Protein Conformation; Protein Domains; Substrate Specificity; Uroporphyrinogens | 2021 |