Page last updated: 2024-09-04

hydroxyl radical and zidovudine triphosphate

hydroxyl radical has been researched along with zidovudine triphosphate in 2 studies

Compound Research Comparison

Studies (hydroxyl radical)	Trials (hydroxyl radical)	Recent Studies (post-2010) (hydroxyl radical)	Studies (zidovudine triphosphate)	Trials (zidovudine triphosphate)	Recent Studies (post-2010) (zidovudine triphosphate)
10,147	26	3,657	199	4	19

Protein Interaction Comparison

Protein	Taxonomy	zidovudine triphosphate (IC50)
DNA polymerase catalytic subunit	Human alphaherpesvirus 1 strain KOS	3.3
DNA polymerase catalytic subunit	Human alphaherpesvirus 1 strain 17	3.3
DNA polymerase catalytic subunit	Human herpesvirus 3 strain Dumas	5.8
DNA polymerase delta catalytic subunit	Homo sapiens (human)	2.3
Reverse transcriptase/RNaseH	Human immunodeficiency virus 1	0.9835

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Amacker, M; Faraj, A; Gosselin, G; Hübscher, U; Imbach, JL; Maga, G; Mathé, C; Sommadossi, JP; Spadari, S	1
Guo, D; Jamburuthugoda, VK; Kim, B; Wedekind, JE	1

Other Studies

2 other study(ies) available for hydroxyl radical and zidovudine triphosphate

Article	Year
Molecular basis for the enantioselectivity of HIV-1 reverse transcriptase: role of the 3'-hydroxyl group of the L-(beta)-ribose in chiral discrimination between D- and L-enantiomers of deoxy- and dideoxy-nucleoside triphosphate analogs. Nucleic acids research, 1999, Feb-15, Volume: 27, Issue:4 Topics: Anti-HIV Agents; Carbohydrates; Catalysis; Deoxycytosine Nucleotides; Deoxyribonucleosides; Dideoxynucleosides; Dideoxynucleotides; DNA; Drug Resistance, Microbial; HIV Reverse Transcriptase; Humans; Hydroxyl Radical; Isoleucine; Kinetics; Nevirapine; Recombinant Fusion Proteins; Reverse Transcriptase Inhibitors; Ribose; Templates, Genetic; Thymine Nucleotides; Tyrosine; Zidovudine	1999
Kinetic evidence for interaction of human immunodeficiency virus type 1 reverse transcriptase with the 3'-OH of the incoming dTTP substrate. Biochemistry, 2005, Aug-09, Volume: 44, Issue:31 Topics: Acyclovir; Amino Acid Substitution; Asparagine; Dideoxynucleotides; Glutamine; HIV Reverse Transcriptase; Hydroxyl Radical; Isoleucine; Kinetics; Models, Molecular; Protein Binding; Substrate Specificity; Thymine Nucleotides; Valine; Zidovudine	2005

Article

Year

Molecular basis for the enantioselectivity of HIV-1 reverse transcriptase: role of the 3'-hydroxyl group of the L-(beta)-ribose in chiral discrimination between D- and L-enantiomers of deoxy- and dideoxy-nucleoside triphosphate analogs.

Nucleic acids research, 1999, Feb-15, Volume: 27, Issue:4

Topics: Anti-HIV Agents; Carbohydrates; Catalysis; Deoxycytosine Nucleotides; Deoxyribonucleosides; Dideoxynucleosides; Dideoxynucleotides; DNA; Drug Resistance, Microbial; HIV Reverse Transcriptase; Humans; Hydroxyl Radical; Isoleucine; Kinetics; Nevirapine; Recombinant Fusion Proteins; Reverse Transcriptase Inhibitors; Ribose; Templates, Genetic; Thymine Nucleotides; Tyrosine; Zidovudine

1999

Kinetic evidence for interaction of human immunodeficiency virus type 1 reverse transcriptase with the 3'-OH of the incoming dTTP substrate.

Biochemistry, 2005, Aug-09, Volume: 44, Issue:31

Topics: Acyclovir; Amino Acid Substitution; Asparagine; Dideoxynucleotides; Glutamine; HIV Reverse Transcriptase; Hydroxyl Radical; Isoleucine; Kinetics; Models, Molecular; Protein Binding; Substrate Specificity; Thymine Nucleotides; Valine; Zidovudine

2005