Compounds > hydroxyl radical
Page last updated: 2024-09-04

hydroxyl radical and wortmannin

hydroxyl radical has been researched along with wortmannin in 3 studies

Compound Research Comparison

Studies
(hydroxyl radical)		Trials
(hydroxyl radical)		Recent Studies (post-2010)
(hydroxyl radical)		Studies
(wortmannin)		Trials
(wortmannin)		Recent Studies (post-2010) (wortmannin)
10,147263,6574,0662726

Protein Interaction Comparison

ProteinTaxonomyhydroxyl radical (IC50)wortmannin (IC50)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformHomo sapiens (human)0.0465
Myosin light chain kinase, smooth muscleGallus gallus (chicken)0.26
Metabotropic glutamate receptor 1Rattus norvegicus (Norway rat)0.0085
Phosphatidylinositol 3-kinase regulatory subunit alphaHomo sapiens (human)0.2368
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformHomo sapiens (human)0.1309
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformHomo sapiens (human)0.0493
Serine/threonine-protein kinase mTORHomo sapiens (human)0.04
Phosphatidylinositol 4-kinase alphaHomo sapiens (human)0.28
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Homo sapiens (human)0.0492
Serine/threonine-protein kinase PLK1Homo sapiens (human)0.4433
Myosin light chain kinase, smooth muscleHomo sapiens (human)2.3567
Phosphoinositide 3-kinase regulatory subunit 5Homo sapiens (human)0.019
Serine/threonine-protein kinase PLK3Homo sapiens (human)0.1057
Phosphatidylinositol 4-kinase betaHomo sapiens (human)0.44

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Deres, P; Halmosi, R; Hideg, K; Kalai, T; Kovacs, K; Sumegi, B; Toth, A; Toth, K1
Altura, BM; Altura, BT; Li, J; Li, W; Liu, W1
Douglas, P; Kurz, EU; Lees-Miller, SP1

Other Studies

3 other study(ies) available for hydroxyl radical and wortmannin

ArticleYear
Akt activation induced by an antioxidant compound during ischemia-reperfusion.
    Free radical biology & medicine, 2003, Nov-01, Volume: 35, Issue:9

    Topics: Androstadienes; Animals; Antioxidants; Caspase 3; Caspases; Energy Metabolism; Enzyme Activation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hydroxyl Radical; Lipid Peroxidation; Magnetic Resonance Spectroscopy; Male; Mexiletine; Molecular Structure; Myocardial Contraction; Phosphatidylinositol 3-Kinases; Phosphocreatine; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrroles; Rats; Rats, Wistar; Reperfusion Injury; Superoxides; Wortmannin

2003
Mechanisms of hydroxyl radical-induced contraction of rat aorta.
    European journal of pharmacology, 2004, Sep-19, Volume: 499, Issue:1-2

    Topics: Androstadienes; Animals; Aorta; Calcium; Carbazoles; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Ferrous Compounds; Genistein; Hydrogen Peroxide; Hydroxyl Radical; In Vitro Techniques; Indoles; Male; Maleimides; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphoinositide-3 Kinase Inhibitors; Proadifen; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Staurosporine; Vasoconstriction; Wortmannin

2004
Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species.
    The Journal of biological chemistry, 2004, Dec-17, Volume: 279, Issue:51

    Topics: Acetylcysteine; Androstadienes; Antibiotics, Antineoplastic; Antineoplastic Agents; Ascorbic Acid; Ataxia Telangiectasia Mutated Proteins; Binding Sites; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cell Nucleus; DNA; DNA Damage; DNA-Binding Proteins; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Inhibitors; Histones; Humans; Hydroxyl Radical; Image Processing, Computer-Assisted; Immunoblotting; Immunoprecipitation; Microscopy, Fluorescence; Oligonucleotides; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Radiation, Ionizing; Reactive Oxygen Species; Serine; Signal Transduction; Threonine; Time Factors; Transcription, Genetic; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Wortmannin

2004