hydroxyl radical has been researched along with tolcapone in 1 studies
| Studies (hydroxyl radical) | Trials (hydroxyl radical) | Recent Studies (post-2010) (hydroxyl radical) | Studies (tolcapone) | Trials (tolcapone) | Recent Studies (post-2010) (tolcapone) |
|---|---|---|---|---|---|
| 10,147 | 26 | 3,657 | 413 | 82 | 132 |
| Protein | Taxonomy | hydroxyl radical (IC50) | tolcapone (IC50) |
|---|---|---|---|
| Transthyretin | Homo sapiens (human) | 3.2 | |
| Catechol O-methyltransferase | Homo sapiens (human) | 0.043 | |
| Catechol O-methyltransferase | Rattus norvegicus (Norway rat) | 0.4661 | |
| Adenosine receptor A2a | Homo sapiens (human) | 0.93 | |
| Genome polyprotein | Dengue virus 2 Thailand/16681/84 | 0.64 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gerlach, M; Kuhn, W; Lehnfeld, R; Riederer, P; Sontag, KH; Waldmeier, P; Xiao, AY | 1 |
1 other study(ies) available for hydroxyl radical and tolcapone
| Article | Year |
|---|---|
The central catechol-O-methyltransferase inhibitor tolcapone increases striatal hydroxyl radical production in L-DOPA/carbidopa treated rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Benzophenones; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catechols; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Hydroxyl Radical; Levodopa; Male; Microdialysis; Nitriles; Nitrophenols; Oxidative Stress; Parkinsonian Disorders; Rats; Rats, Wistar; Tolcapone | 2001 |