hydroxyl radical has been researched along with thiourea in 115 studies
| Studies (hydroxyl radical) | Trials (hydroxyl radical) | Recent Studies (post-2010) (hydroxyl radical) | Studies (thiourea) | Trials (thiourea) | Recent Studies (post-2010) (thiourea) |
|---|---|---|---|---|---|
| 10,147 | 26 | 3,657 | 6,959 | 46 | 1,737 |
| Protein | Taxonomy | hydroxyl radical (IC50) | thiourea (IC50) |
|---|---|---|---|
| Urease | Canavalia ensiformis (jack bean) | 0.56 | |
| Serine-protein kinase ATM | Homo sapiens (human) | 0.2 | |
| Serine/threonine-protein kinase ATR | Homo sapiens (human) | 0.2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (26.09) | 18.7374 |
| 1990's | 47 (40.87) | 18.2507 |
| 2000's | 27 (23.48) | 29.6817 |
| 2010's | 11 (9.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Foerder, CA; Zager, RA | 1 |
| Barreto, JC; Miller, TA; Schmidt, KL; Smith, GS; Tornwall, MS | 1 |
| Pang, JA; Smith, S; Thomas, MJ | 1 |
| Houser, MT; Milner, LS; Wei, SH | 1 |
| Shah, SV; Walker, PD | 2 |
| Floyd, RA; Gutteridge, JM; Maidt, L; Price, S; Schneider, JE | 1 |
| Brandi, G; Cantoni, O; Cattabeni, FC; Salvaggio, L; Schiavano, GF | 1 |
| Callahan, HL; Crouch, RK; James, ER | 1 |
| Uggla, AH | 1 |
| Blount, S; Griffiths, HR; Lunec, J | 1 |
| Bagchi, D; Das, DK; Prasad, R | 1 |
| Vartio, T | 1 |
| Albano, A; Brandi, G; Cantoni, O; Cattabeni, F | 1 |
| Das, DK; Prasad, MR | 1 |
| Das, DK; George, A; Liu, XK; Rao, PS | 1 |
| Altmiller, DH; Floyd, RA; Rickard, RC; Watson, JJ; Wong, PK | 1 |
| Boyce, NW; Campbell, D; Holdsworth, SR | 1 |
| Castelli, A; Martorana, GE; Meucci, E; Miggiano, GA; Mordente, A; Santini, SA | 1 |
| Ishikawa, Y; Kuroda, M; Murakami, K | 1 |
| Bello, SL; Hayden, RE; Paniello, RC; Yeung, CS | 1 |
| Anderson, DL; Grizzle, MK; Olson, NC | 1 |
| Shah, SV | 1 |
| Eneff, KL; Floyd, RA; Hogsett, WE; Tingey, DT; West, MS | 1 |
| Alessandri, C; Balsano, F; Cordova, C; Ghiselli, A; Iuliano, L; Violi, F | 1 |
| Shah, SV; Thakur, V; Walker, PD | 1 |
| Barr, SB; Bowdy, BD; Gillespie, MN; Haven, CA; Pauly, TH | 1 |
| Bishop, MJ; Cheney, FW; Chi, EY; Su, M | 1 |
| Gutteridge, JM; Quinlan, GJ | 1 |
| Demling, RH; Fox, R; Wong, C | 1 |
| Jacob, HS; van Asbeck, BS; Vercellotti, GM | 1 |
| Alcantara-Gomes, R; Costa de Oliveira, R; Felzenszwalb, I; Menck, CF; Van Sluys, MA | 1 |
| Berger, EM; Curtis, WE; Linas, SL; Muldrow, ME; Parker, NB; Repine, JE | 1 |
| Gillespie, MN; Jay, M; Kojima, S; Kunitomo, M | 1 |
| Manabe, M | 1 |
| Fox, RB | 1 |
| Berger, EM; Bowman, CM; Fox, RB; Harada, RN; Repine, JE; Shasby, DM; Vatter, A | 1 |
| Berger, EM; Johansen, KS; Repine, JE | 1 |
| Milo-Goldzweig, I; Segal, R | 1 |
| Chen, DZ; Katsura, M; Kuriyama, K; Narihara, H; Ohkuma, S | 1 |
| Batabyal, SK; Chakraborti, S; Chakraborti, T | 1 |
| Huang, HS; Longhurst, JC; Pan, HL; Stahl, GL | 1 |
| Guice, KS; Magee, JC; Myers, SI; Oldham, KT; Turnage, RH | 1 |
| Furukawa, Y; Sugiyama, M; Susa, N; Ueno, S | 1 |
| de Graaf, L; de Vos, NM; Nottet, HS; van Asbeck, BS; Verhoef, J; Visser, MR | 1 |
| Liu, M; Okada, S | 1 |
| Chavez-Chavez, RH; Delano, FA; Miyasaka, M; Schmid-Schönbein, GW; Suematsu, M; Tamatani, T; Yee, TT; Zweifach, BW | 1 |
| Krishnamurthy, S; Prabhu, HR | 1 |
| Bosch, MA; Romero, C | 1 |
| Holthofer, H; Schlondorff, D; Stenzel, KH; Suthanthiran, M; Zuckerman, AL | 1 |
| Fisher, PW; Huang, YC; Kennedy, TP; Piantadosi, CA | 1 |
| Chagas, AC; da-Luz, PL; Laurindo, FR; Pileggi, F | 1 |
| Longhurst, JC; Pan, HL; Stahl, GL | 1 |
| Chakraborti, S; Chakraborti, T; Ghosh, JJ; Ghosh, SK; Kar, S; Roychoudhury, S | 1 |
| Chen, DZ; Guo, JL; Katsura, M; Kuriyama, K; Ohkuma, S | 1 |
| Fu, LW; Halliwell, B; Longhurst, JC; O'Neill, CA | 1 |
| Barnes, PJ; Lei, YH; Rogers, DF | 1 |
| Bharadwaj, LA; Prasad, K | 1 |
| Fujitsuka, N; Ienaga, K; Nakamura, K; Oura, H; Yokozawa, T | 1 |
| Hsu, TH; Kou, YR; Lai, CJ; Lin, YS | 1 |
| Aprile, F; Frati, E; Front, P; Khatib, AM; Mitrovic, DR; Panasyuk, A | 1 |
| Halliwell, B; Whiteman, M | 1 |
| Mizukawa, H; Okabe, E | 1 |
| Cowman, MK; Li, M; Rosenfeld, L; Vilar, RE | 1 |
| Bay, BH; Chan, YG; Paramanantham, R; Sit, KH | 1 |
| Asad, NR; Furtado, FA; Leitão, AC | 1 |
| Agah, A; Collard, CD; Stahl, GL | 1 |
| Hara, A; Hibino, Y; Higo, A; Katsura, M; Ohkuma, S | 1 |
| Hara, A; Hibino, Y; Ishikawa, E; Katsura, M; Kuriyama, K; Ohkuma, S; Shirotani, K | 1 |
| Acker, H; Jungermann, K; Kietzmann, T; Porwol, T; Zierold, K | 1 |
| Czarnowska, E; Karwatowska-Prokopczuk, E; Kurzydlowski, K | 1 |
| Hara, A; Hibino, Y; Higo, A; Katsura, M; Ohkuma, S; Tarumi, C | 1 |
| Farhan Asad, S; Hadi, SM; Singh, S | 1 |
| Aeed, H; Avni, Y; Bruck, R; Halpern, Z; Matas, Z; Shirin, H; Zaidel, L | 1 |
| Narita, H; Odawara, A; Suzuki, T; Suzumura, K; Tanaka, K; Yasuhara, M | 1 |
| Kim, H; Kim, KH; Seo, JY | 1 |
| Abiko, Y; Hara, A; Hashizume, H; Nakamura, M; Shishido, N; Suzuki, T; Ushikubi, F | 1 |
| Delano, FA; Schmid-Schönbein, GW; Wilms, H | 1 |
| Hsu, TH; Kou, YR; Lai, YL | 1 |
| Khanna, A; Savin, VJ; Sharma, M; Sharma, R | 1 |
| Aizawa, H; Fukuyama, S; Hara, N; Inoue, H; Koto, H; Matsumoto, K | 1 |
| Das, CK; Das, KC | 1 |
| Furukawa, Y; Ishii, M; Kashimoto, T; Nishimura, Y; Sasaki, YF; Sugiyama, M; Susa, N; Ueda, J; Ueno, S; Yasuno, M; Yokoi, K | 1 |
| Hara, A; Ito, Z; Kusakari, J; Tabuchi, K; Tsuji, S | 1 |
| Antunes, LM; Araújo, MC; Takahashi, CS | 1 |
| Ding, Y; Gonick, HC; Liang, K; Vaziri, ND; Wei, L | 1 |
| Bravman, J; Hubbard, AK; Mossman, BT; Shukla, A; Timblin, CR | 1 |
| Higo, A; Katsura, M; Mohri, Y; Ohkuma, S; Shirotani, K; Shuto, K; Takesue, M; Tarumi, C | 1 |
| Ho, CY; Kou, YR; Lin, YS; Tang, GJ | 1 |
| Cameron, NE; Cotter, MA; McCabe, L; Tuck, Z | 1 |
| Arvieux, J; Berthou, F; Darnige, L; Hachulla, E; Regnault, V; Youinou, P | 1 |
| Amati, M; Bolognini, L; Carmignani, M; Coloccini, S; Fenoglio, I; Fubini, B; Governa, M; Valentino, M; Volpe, AR | 1 |
| Antholine, WE; Frei, B; Zhu, BZ | 1 |
| Beresewicz, A; Maczewski, M | 1 |
| Frenkel, K; Huang, X; Maes, D; Mammone, T; Marenus, K; Pelle, E | 1 |
| Baek, SM; Jung, JS; Kim, JH; Kim, YK; Kwon, CH; Woo, JS | 1 |
| Jian, L; Lang, HQ | 1 |
| Chang, SY; Ho, CY; Kou, YR; Tsai, TL | 1 |
| Burcham, P; Farmer, DS; Marin, PD | 1 |
| Alvarez, AI; Fernandes, P; Mendoza, G; Merino, G; Molina, AJ; Prieto, JG; Pulido, MM; Real, R | 1 |
| Barrera, D; Maldonado, PD; Medina-Campos, ON; Mendoza-Patiño, N; Pedraza-Chaverri, J; Rocha, D; Segoviano-Murillo, S | 1 |
| Chen, SC; Chen, WC | 1 |
| Wang, X; Zhao, X | 1 |
| Chiang, FT; Chu, SH; Hsin, HT; Lin, LY; Tseng, CD; Tseng, YZ; Yeh, HI; Yeih, DF | 1 |
| Ahmad, R; Khaket, TP | 1 |
| Cil, O; Ertunc, M; Gucer, KS; Iskit, AB; Onur, R; Ozaltin, F | 1 |
| Choi, H; Lee, DG | 1 |
| Chiang, LL; Hsu, CC; Lin, YJ; Lin, YS; Su, CL; Weng, WH | 1 |
| Li, M; Nakayama, J; Sonomoto, K; Toshimitsu, N; Yoneyama, F; Zendo, T | 1 |
| Fattorini, L; Giannoni, F; Mustazzolu, A; Piccaro, G; Pietraforte, D | 1 |
| Cathro, P; Damiani, F; Heithersay, GS; Lou, EK; Marino, V | 1 |
| Bittar, A; Chung, JM; Jun, J; La, JH; Leem, JW; Wang, J | 1 |
| Biondi, R; Bottiglieri, L; Brancorsini, S; Brillo, E; Capodicasa, E; Cretoiu, D; Egidi, MG; Gerli, S; Micu, R; Poli, G; Renzo, GCD; Suciu, N | 1 |
| Ajiboye, TO | 1 |
| Ajitkumar, P; Nair, RR; Sebastian, J; Sharan, D; Swaminath, S | 1 |
1 trial(s) available for hydroxyl radical and thiourea
| Article | Year |
|---|---|
The ability of thiourea to scavenge hydrogen peroxide and hydroxyl radicals during the intra-coronal bleaching of bloodstained root-filled teeth.
Topics: Antioxidants; Diffusion; Humans; Hydrogen Peroxide; Hydroxyl Radical; Oxidants; Thiourea; Tooth Bleaching; Tooth Root | 2006 |
114 other study(ies) available for hydroxyl radical and thiourea
| Article | Year |
|---|---|
Effects of inorganic iron and myoglobin on in vitro proximal tubular lipid peroxidation and cytotoxicity.
Topics: Acute Kidney Injury; Animals; Benzoates; Benzoic Acid; Deferoxamine; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Iron; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Myoglobin; Perfusion; Rats; Rats, Inbred Strains; Salicylates; Superoxide Dismutase; Thiourea | 1992 |
Protective effect of dimethylthiourea against mucosal injury in rat stomach. Implications for hydroxyl radical mechanism.
Topics: Animals; Dose-Response Relationship, Drug; Ethanol; Female; Free Radicals; Gastric Mucosa; Hydroxides; Hydroxyl Radical; Indomethacin; Rats; Rats, Inbred Strains; Thiourea | 1992 |
The use of water-soluble radical scavengers to detect hydroxyl radical formation by polymorphonuclear leukocytes.
Topics: Allopurinol; Benzoates; Benzoic Acid; Cytochrome c Group; Dimethyl Sulfoxide; Free Radical Scavengers; Free Radicals; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; L-Lactate Dehydrogenase; Mannitol; Neutrophils; Oxidation-Reduction; Solubility; Tetradecanoylphorbol Acetate; Thiourea; Water | 1991 |
Amelioration of glomerular injury in doxorubicin hydrochloride nephrosis by dimethylthiourea.
Topics: Acetylglucosaminidase; Albuminuria; Animals; Benzoates; Benzoic Acid; Creatine; Dimethyl Sulfoxide; Disease Models, Animal; Doxorubicin; Free Radical Scavengers; Glomerular Filtration Rate; Glutathione; Hydroxides; Hydroxyl Radical; Injections, Intravenous; Kidney Cortex; Male; Muramidase; Nephrosis; Proteinuria; Rats; Rats, Inbred Strains; Thiourea | 1991 |
Hydrogen peroxide cytotoxicity in LLC-PK1 cells: a role for iron.
Topics: Animals; Cell Death; Cell Line; Deferoxamine; Free Radical Scavengers; Free Radicals; Glucose; Glucose Oxidase; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Iron; Kidney Tubules, Proximal; Thiourea | 1991 |
Methylene blue plus light mediates 8-hydroxy 2'-deoxyguanosine formation in DNA preferentially over strand breakage.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Catalase; Deferoxamine; Deoxyguanosine; DNA Damage; DNA, Superhelical; Free Radicals; Hydroxides; Hydroxyl Radical; Light; Magnesium; Mannitol; Methylene Blue; Plasmids; Thiopental; Thiourea | 1990 |
Role of free radicals produced during the metabolism of mitomycin C in Escherichia coli inactivation.
Topics: Dimethyl Sulfoxide; Escherichia coli; Ethanol; Free Radicals; Hydroxides; Hydroxyl Radical; Mitomycin; Mitomycins; Mutation; Oxygen; Superoxide Dismutase; Thiourea | 1990 |
Hydrogen peroxide is the most toxic oxygen species for Onchocerca cervicalis microfilariae.
Topics: Animals; Catalase; Glucose Oxidase; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Microfilariae; Onchocerca; Oxygen; Rose Bengal; Singlet Oxygen; Superoxide Dismutase; Superoxides; Thiourea; Xanthine; Xanthine Oxidase; Xanthines | 1990 |
The induction of chromosomal aberrations and SCEs by visible light in combination with dyes. II. Cell cycle dependence, and the effect of hydroxyl radical scavengers during light exposure in cultures of Chinese hamster ovary cells sensitized with acridine
Topics: Acridine Orange; Animals; Cell Cycle; Cell Line; Chromosome Aberrations; Chromosomes; Cricetinae; Dose-Response Relationship, Radiation; Free Radicals; Hydroxides; Hydroxyl Radical; Light; Mannitol; Sister Chromatid Exchange; Thiourea | 1990 |
Reactive oxygen species induce antigenic changes in DNA.
Topics: Animals; Antibodies; Ascorbic Acid; Cattle; Deferoxamine; DNA; Epitopes; Free Radicals; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Immune Sera; Immunoglobulin A; Immunoglobulin G; Immunoglobulin Isotypes; Immunoglobulin M; Lupus Erythematosus, Systemic; Nucleic Acid Denaturation; Oxygen; Thiourea | 1989 |
Direct scavenging of free radicals by captopril, an angiotensin converting enzyme inhibitor.
Topics: Allopurinol; Captopril; Cytochrome c Group; Free Radicals; Hydroxides; Hydroxyl Radical; Hypochlorous Acid; Kinetics; Superoxide Dismutase; Superoxides; Thiourea | 1989 |
Regular fragmentation of hydrogen peroxide-treated fibronectin.
Topics: Binding Sites; Deferoxamine; Electrophoresis, Polyacrylamide Gel; Fibronectins; Free Radicals; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Immunoblotting; Macromolecular Substances; Molecular Weight; Pentetic Acid; Peptide Fragments; Polystyrenes; Polyvinyls; Thiourea | 1989 |
Role of hydroxyl radicals in Escherichia coli killing induced by hydrogen peroxide.
Topics: Deferoxamine; Dimethyl Sulfoxide; Escherichia coli; Ethanol; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Iron; Kinetics; Thiourea | 1989 |
Effect of oxygen-derived free radicals and oxidants on the degradation in vitro of membrane phospholipids.
Topics: Animals; Catalase; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Intracellular Membranes; Male; Membrane Lipids; Microsomes; Myocardium; Phospholipids; Rats; Rats, Inbred Strains; Superoxide Dismutase; Superoxides; Thiourea | 1989 |
Detection of hydroxyl radical in the mitochondria of ischemic-reperfused myocardium by trapping with salicylate.
Topics: Animals; Catalase; Chromatography, High Pressure Liquid; Coronary Disease; Dimethyl Sulfoxide; Free Radicals; Hydroxides; Hydroxyl Radical; Male; Mitochondria, Heart; Myocardial Reperfusion; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Superoxide Dismutase; Thiourea | 1989 |
Hydroxyl free radical adduct of deoxyguanosine: sensitive detection and mechanisms of formation.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Chromatography, High Pressure Liquid; Deoxyguanosine; Electrochemistry; Ethanol; Free Radical Scavengers; Free Radicals; Hydroxyl Radical; Thiourea | 1986 |
Modulation of normobaric pulmonary oxygen toxicity by hydroxyl radical inhibition.
Topics: Animals; Capillary Permeability; Deferoxamine; Hydroxides; Hydroxyl Radical; Lung; Lung Diseases; Male; Organ Size; Oxygen; Rats; Rats, Inbred Strains; Thiourea | 1987 |
Alkaline phosphatase inactivation by mixed function oxidation systems.
Topics: Alkaline Phosphatase; Antioxidants; Ascorbic Acid; Catalase; Cations, Divalent; Copper; Ferric Compounds; Ferrous Compounds; Free Radicals; Glutathione; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Kinetics; Mercaptoethanol; Metals; Mixed Function Oxygenases; Oxidation-Reduction; Peroxidase; Superoxide Dismutase; Thiourea; Uric Acid; Vitamin E; Xanthine Oxidase | 1987 |
Role of hydroxyl radicals derived from granulocytes in lung injury induced by phorbol myristate acetate.
Topics: Animals; Body Weight; Bronchoalveolar Lavage Fluid; Catalase; Cell Count; Free Radicals; Granulocytes; Histocytochemistry; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Lung; Lung Diseases; Male; Organ Size; Rabbits; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Thiourea | 1987 |
The effect of hydroxyl radical scavenging on acute axial-random skin flap survival.
Topics: Animals; Graft Survival; Hydroxides; Hydroxyl Radical; Male; Microcirculation; Rats; Rats, Inbred Strains; Skin; Surgical Flaps; Thiourea | 1988 |
Dimethylthiourea attenuates endotoxin-induced acute respiratory failure in pigs.
Topics: Acute Disease; Animals; Blood Gas Analysis; Blood Pressure; Endotoxins; Free Radicals; Hydroxides; Hydroxyl Radical; Pulmonary Artery; Pulmonary Gas Exchange; Pulmonary Wedge Pressure; Respiratory Insufficiency; Swine; Thiourea | 1987 |
Evidence suggesting a role for hydroxyl radical in passive Heymann nephritis in rats.
Topics: Animals; Antibodies, Anti-Idiotypic; Benzoates; Benzoic Acid; Deferoxamine; Free Radicals; Hydroxides; Hydroxyl Radical; Kidney; Male; Nephritis; Proteinuria; Rats; Rats, Inbred Strains; Superoxide Dismutase; Thiourea | 1988 |
Hydroxyl free radical mediated formation of 8-hydroxyguanine in isolated DNA.
Topics: Animals; Cattle; DNA; DNA Damage; Guanine; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Thiourea; Ultraviolet Rays | 1988 |
Influence of hydroxyl radical scavengers on platelet function.
Topics: Adult; Blood Platelets; Catalase; Chelating Agents; Dimethyl Sulfoxide; Ethylene Glycols; Female; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; Male; Malondialdehyde; Methylurea Compounds; Platelet Aggregation Inhibitors; Platelet Function Tests; Prostaglandin-Endoperoxide Synthases; Superoxide Dismutase; Thiourea; Thromboxane B2 | 1988 |
Evidence suggesting a role for hydroxyl radical in glycerol-induced acute renal failure.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Free Radicals; Glycerol; Hydroxides; Hydroxyl Radical; Kidney; Male; Rats; Rats, Inbred Strains; Reference Values; Thiourea | 1988 |
Evidence suggesting a role for hydroxyl radical in puromycin aminonucleoside-induced proteinuria.
Topics: Animals; Benzoates; Benzoic Acid; Deferoxamine; Dimethyl Sulfoxide; Hydroxides; Hydroxyl Radical; Male; Proteinuria; Puromycin; Puromycin Aminonucleoside; Rats; Rats, Inbred Strains; Thiourea | 1988 |
Evidence for hydroxyl radical involvement in group B streptococcus-induced pulmonary hypertension and arterial hypoxemia in young piglets.
Topics: Animals; Free Radicals; Hydroxides; Hydroxyl Radical; Hypertension, Pulmonary; Hypoxia; Pulmonary Edema; Streptococcal Infections; Streptococcus agalactiae; Swine; Thiourea | 1988 |
Dimethylthiourea does not ameliorate reperfusion lung injury in dogs or rabbits.
Topics: Animals; Disease Models, Animal; Dogs; Hydroxides; Hydroxyl Radical; Ischemia; Leukopenia; Lung; Lung Injury; Macrophages; Neutrophils; Pulmonary Edema; Rabbits; Thiourea | 1988 |
Hydroxyl radical generation by the tetracycline antibiotics with free radical damage to DNA, lipids and carbohydrate in the presence of iron and copper salts.
Topics: Animals; Carbohydrate Metabolism; Cattle; Copper; Deoxyribose; DNA Damage; Ferric Compounds; Free Radicals; Hydroxides; Hydroxyl Radical; Lipid Metabolism; Lipid Peroxidation; Liposomes; Mannitol; Tetracyclines; Thiourea | 1988 |
Effect of hydroxyl radical scavenging on endotoxin-induced lung injury.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Capillary Permeability; Endotoxins; Escherichia coli; Free Radicals; Hemodynamics; Hydroxides; Hydroxyl Radical; Lung; Lymph; Neutrophils; Proteins; Sheep; Thiourea; Thromboxane B2 | 1985 |
Oxygen radical-induced erythrocyte hemolysis by neutrophils. Critical role of iron and lactoferrin.
Topics: Cytoplasmic Granules; Erythrocytes; Free Radicals; Hemolysis; Humans; Hydroxides; Hydroxyl Radical; Lactoferrin; Mannitol; Methemoglobin; Neutrophils; Oxygen; Tetradecanoylphorbol Acetate; Thiourea | 1985 |
Ascorbate-copper induced DNA lesions and repair in Escherichia coli K12 cells.
Topics: Ascorbic Acid; beta-Galactosidase; Catalase; Copper; DNA Repair; DNA, Bacterial; Escherichia coli; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Mutation; Oxidation-Reduction; Rec A Recombinases; Thiourea | 1986 |
Hydrogen peroxide causes dimethylthiourea consumption while hydroxyl radical causes dimethyl sulfoxide consumption in vitro.
Topics: Chromatography, Gas; Dimethyl Sulfoxide; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Iron; Oxygen; Superoxide Dismutase; Thiourea | 1985 |
Coronary and myocardial effects of activated neutrophils in perfused rabbit hearts.
Topics: Animals; Catalase; Coronary Circulation; Hydroxides; Hydroxyl Radical; Myocardial Contraction; Neutrophils; Nitroprusside; Rabbits; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Thiourea; Vascular Resistance | 1986 |
Regeneration and degradation of basal lamina-associated anionic sites in vitro.
Topics: Anions; Basement Membrane; Chondroitin Sulfate Proteoglycans; Glycosaminoglycans; Heparan Sulfate Proteoglycans; Heparitin Sulfate; Humans; Hydroxides; Hydroxyl Radical; Membrane Potentials; Organ Culture Techniques; Proteoglycans; Skin; Sodium Chloride; Thiourea | 1987 |
Prevention of granulocyte-mediated oxidant lung injury in rats by a hydroxyl radical scavenger, dimethylthiourea.
Topics: Animals; Cell Aggregation; Chemotaxis, Leukocyte; Cytoplasmic Granules; Free Radicals; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Kinetics; Lung; Lung Injury; Neutrophils; Oxygen; Pulmonary Edema; Rats; Rats, Inbred Strains; Superoxides; Thiourea | 1984 |
Potential mechanisms of lung injury from hydroxyl radical.
Topics: Bacteria; Biological Assay; Dimethyl Sulfoxide; Free Radicals; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Lung; Lung Diseases; Neutrophils; Staphylococcus aureus; Thiourea | 1981 |
Hydroxyl radical scavengers produce similar decreases in the chemiluminescence responses and bactericidal activities of neutrophils.
Topics: Catalase; Dimethyl Sulfoxide; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; Mannitol; Methylurea Compounds; Neutrophils; Phagocytosis; Staphylococcus aureus; Superoxide Dismutase; Thiourea | 1984 |
Hemolysis caused by cetomacrogol 1000: evidence for hydroxyl radical participation.
Topics: Animals; Catalase; Cetomacrogol; Free Radicals; Hemolysis; Histidine; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Light; Mannitol; Polyethylene Glycols; Rats; Saponins; Superoxide Dismutase; Thiourea | 1983 |
Removal of hydroxyl radical increases nitric oxide generators-induced [3H]GABA release from mouse cerebral cortical neurons.
Topics: Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Free Radical Scavengers; gamma-Aminobutyric Acid; Hydroxyl Radical; Mannitol; Mice; Mice, Inbred Strains; Nitric Oxide; Thiourea; Uric Acid | 1995 |
Role of hydroxyl radical in the stimulation of arachidonic acid release caused by H2O2 in pulmonary smooth muscle cells: protective effect of anion channel blocker.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Arachidonic Acid; Cells, Cultured; Deferoxamine; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Ion Channels; Muscle, Smooth, Vascular; Pulmonary Artery; Rabbits; Siderophores; Thiourea | 1995 |
Ischemia- and reperfusion-sensitive cardiac sympathetic afferents: influence of H2O2 and hydroxyl radicals.
Topics: Animals; Bradykinin; Cats; Deferoxamine; Female; Free Radical Scavengers; Heart Conduction System; Hydrogen Peroxide; Hydroxyl Radical; Iron; Male; Myocardial Ischemia; Myocardial Reperfusion; Neurons, Afferent; Sympathetic Nervous System; Thiourea | 1995 |
Complement activation by the hydroxyl radical during intestinal reperfusion.
Topics: Animals; Chemotactic Factors; Complement Activation; Complement C5a; Deferoxamine; Disease Models, Animal; Hydroxyl Radical; Intestines; Male; Neutrophils; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Thiourea | 1994 |
Effect of dimethylthiourea on chromium (VI)-induced DNA single-strand breaks in Chinese hamster V-79 cells.
Topics: Animals; Cells, Cultured; Chromates; Cricetinae; DNA Damage; Drug Interactions; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Hydroxyl Radical; Oxidation-Reduction; Thiourea | 1995 |
Role for oxygen radicals in self-sustained HIV-1 replication in monocyte-derived macrophages: enhanced HIV-1 replication by N-acetyl-L-cysteine.
Topics: Acetylcysteine; Drug Interactions; Ferrous Compounds; Free Radical Scavengers; Glutathione; HIV-1; Humans; Hydroxyl Radical; Macrophages; Oxidation-Reduction; Reactive Oxygen Species; Stimulation, Chemical; Thiourea; Urea; Virus Replication | 1994 |
Induction of free radicals and tumors in the kidneys of Wistar rats by ferric ethylenediamine-N,N'-diacetate.
Topics: Adenocarcinoma; Adenoma; Animals; Catalase; Cell Transformation, Neoplastic; Deoxyribose; Edetic Acid; Ferric Compounds; Formates; Hydrogen Peroxide; Hydroxyl Radical; Kidney; Kidney Neoplasms; Lipid Peroxidation; Male; Mannitol; Nitrilotriacetic Acid; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Superoxides; Thiobarbituric Acid Reactive Substances; Thiourea | 1994 |
In vivo visualization of oxidative changes in microvessels during neutrophil activation.
Topics: 2,2'-Dipyridyl; Animals; Antigens, CD; CD18 Antigens; Cell Adhesion; Endothelium, Vascular; Fluoresceins; Fluorescent Dyes; Free Radical Scavengers; Hydroxides; Hydroxyl Radical; Iron; Iron Chelating Agents; Male; Microcirculation; Neutrophils; Oxidation-Reduction; Peroxides; Platelet Activating Factor; Rats; Rats, Wistar; tert-Butylhydroperoxide; Thiourea | 1993 |
Ascorbate-dependent formation of hydroxyl radicals in the presence of iron chelates.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Ascorbic Acid; Catalase; Edetic Acid; Ferrous Compounds; Formates; Free Radical Scavengers; Histidine; Hydroxyl Radical; Iron Chelating Agents; Kinetics; Mannitol; Oxidation-Reduction; Superoxide Dismutase; Thiourea | 1993 |
Effect of dimethylthiourea in phosphatidylcholine biosynthesis by rat lung during reversible endotoxic shock.
Topics: Animals; Body Weight; Hydroxyl Radical; Lipid Peroxidation; Lipopolysaccharides; Lung; Male; Organ Size; Phosphatidylcholines; Rats; Rats, Wistar; Shock, Septic; Superoxide Dismutase; Thiourea | 1993 |
Modulation of mouse mesangial cell proliferation by thiourea and lipoxygenase inhibitors.
Topics: Animals; Cell Division; Free Radical Scavengers; Glomerular Mesangium; Hydroxyl Radical; Lipoxygenase; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred BALB C; Prostaglandin-Endoperoxide Synthases; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thiourea | 1994 |
PO2-dependent hydroxyl radical production during ischemia-reperfusion lung injury.
Topics: Animals; Catalase; Glutathione; Hydroxyl Radical; Male; Oxygen; Partial Pressure; Pulmonary Circulation; Rabbits; Reperfusion Injury; Superoxide Dismutase; Thiourea | 1993 |
Antagonizing the hydroxyl ion free radical (HO.) does not abolish reperfusion ventricular fibrillation in anesthetized dogs.
Topics: Anesthesia; Animals; Deferoxamine; Dogs; Female; Free Radical Scavengers; Hemodynamics; Hydroxyl Radical; Male; Myocardial Reperfusion; Thiourea; Ventricular Fibrillation | 1993 |
Activation of ischemia- and reperfusion-sensitive abdominal visceral C fiber afferents. Role of hydrogen peroxide and hydroxyl radicals.
Topics: Abdomen; Action Potentials; Animals; Cats; Deferoxamine; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Ischemia; Nerve Fibers; Neurons, Afferent; Reactive Oxygen Species; Reperfusion; Thiourea; Viscera | 1993 |
Protective role of anion channel blocker in lipid peroxidation caused by H2O2 in microsomes of bovine pulmonary arterial smooth muscle tissue.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Cattle; Deferoxamine; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Ion Channels; Lipid Peroxidation; Microsomes; Muscle, Smooth, Vascular; Pulmonary Artery; Thiourea | 1996 |
Hydroxyl radical scavengers enhance nitric oxide-evoked acetylcholine release from mouse cerebral cortical neurons.
Topics: Acetylcholine; Analysis of Variance; Animals; Cells, Cultured; Cerebral Cortex; Free Radical Scavengers; Hydroxyl Radical; Mannitol; Mice; Neurons; Nitric Oxide; Nitroprusside; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Thiourea; Uric Acid | 1995 |
Hydroxyl radical production during myocardial ischemia and reperfusion in cats.
Topics: Animals; Cats; Deferoxamine; Female; Free Radical Scavengers; Heart Ventricles; Hydroxyl Radical; Lactic Acid; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Organ Size; Siderophores; Thiourea | 1996 |
Involvement of hydroxyl radicals in neurogenic airway plasma exudation and bronchoconstriction in guinea-pigs in vivo.
Topics: Animals; Bronchoconstriction; Catalase; Exudates and Transudates; Free Radical Scavengers; Glycopeptides; Guinea Pigs; Hydrogen Peroxide; Hydroxyl Radical; Male; Oxidants; Protease Inhibitors; Smoking; Substance P; Superoxide Dismutase; Thiourea; Vagus Nerve | 1996 |
Hydroxyl radical--a mediator of acetylcholine-induced vascular relaxation.
Topics: Acetylcholine; Animals; Aorta; Dose-Response Relationship, Drug; Free Radical Scavengers; Glyburide; Hydroxyl Radical; In Vitro Techniques; Mannitol; Norepinephrine; Rabbits; Superoxide Dismutase; Thiourea; Time Factors; Vasoconstriction; Vasodilation | 1996 |
In vivo effect of hydroxyl radical scavenger on methylguanidine production from creatinine.
Topics: Animals; Creatinine; Free Radical Scavengers; Hydroxyl Radical; Injections, Intraperitoneal; Male; Methylguanidine; Rats; Rats, Wistar; Thiourea; Uremia | 1997 |
Involvement of hydroxyl radical in the immediate ventilatory responses to inhaled wood smoke in rats.
Topics: Animals; Capsaicin; Deferoxamine; Free Radical Scavengers; Hydroxyl Radical; Iron; Rats; Rats, Sprague-Dawley; Respiratory Mechanics; Siderophores; Smoke; Thiourea; Wood | 1997 |
Degradation of hyaluronic acid by photosensitized riboflavin in vitro. Modulation of the effect by transition metals, radical quenchers, and metal chelators.
Topics: Animals; Aspirin; Azides; Catalase; Cattle; Chelating Agents; Dimethyl Sulfoxide; Hyaluronic Acid; Hydrogen-Ion Concentration; Hydroxyl Radical; Mannitol; Metals; Oxygen; Reactive Oxygen Species; Riboflavin; Singlet Oxygen; Sodium Azide; Superoxide Dismutase; Synovial Fluid; Thiourea; Ultraviolet Rays; Viscosity | 1997 |
Thiourea and dimethylthiourea inhibit peroxynitrite-dependent damage: nonspecificity as hydroxyl radical scavengers.
Topics: alpha 1-Antitrypsin; Enzyme Inhibitors; Free Radical Scavengers; Hydroxyl Radical; Nitrates; Thiourea; Tyrosine | 1997 |
Inhibition by singlet molecular oxygen of the vascular reactivity in rabbit mesenteric artery.
Topics: Acetylcholine; Animals; Catalase; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Fluorescent Dyes; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nitroglycerin; Photolysis; Rabbits; Rose Bengal; Spin Labels; Spin Trapping; Superoxide Dismutase; Superoxides; Thiourea; Ultraviolet Rays; Vasodilator Agents | 1997 |
Degradation of hyaluronan by peroxynitrite.
Topics: Benzoates; Benzoic Acid; Dimethyl Sulfoxide; Electrophoresis, Agar Gel; Hyaluronic Acid; Hydroxyl Radical; Mannitol; Molecular Weight; Nitrates; Thiourea; Viscosity | 1997 |
Hydroxyl free radicals generated by vanadyl[IV] induce cell blebbing in mitotic human Chang liver cells.
Topics: Apoptosis; Cells, Cultured; Chlorides; Free Radical Scavengers; Glucose; Glutathione; Humans; Hydroxyl Radical; Liver; Microscopy, Confocal; Microscopy, Electron, Scanning; Mitosis; Oxidative Stress; Spectrophotometry, Ultraviolet; Telophase; Thiourea; Vanadates; Zinc Compounds | 1997 |
Effects of 1,10-phenanthroline and hydrogen peroxide in Escherichia coli: lethal interaction.
Topics: 2,2'-Dipyridyl; Benzoates; Benzoic Acid; Chelating Agents; Copper; Deferoxamine; Escherichia coli; Ethanol; Exodeoxyribonucleases; Ferric Compounds; Ferrous Compounds; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Intercalating Agents; Iron; Oxidants; Phenanthrolines; Thiourea | 1997 |
Complement activation following reoxygenation of hypoxic human endothelial cells: role of intracellular reactive oxygen species, NF-kappaB and new protein synthesis.
Topics: Cell Hypoxia; Cells, Cultured; Complement Activation; Complement C3b; Deferoxamine; Dose-Response Relationship, Drug; Endothelium, Vascular; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hydroxyl Radical; NF-kappa B; Oxypurinol; Protein Biosynthesis; Reactive Oxygen Species; Reperfusion Injury; Thiourea; Umbilical Veins | 1998 |
Enhancement of peroxynitrite-evoked acetylcholine release by hydroxyl radical scavengers from mouse cerebral cortical neurons.
Topics: Acetylcholine; Animals; Calcium; Cells, Cultured; Cerebral Cortex; Cricetinae; Dose-Response Relationship, Drug; Exocytosis; Free Radical Scavengers; Hydroxyl Radical; Mice; Nerve Tissue Proteins; Neurons; Nitrates; Oxidants; Thiourea | 1998 |
Mechanisms for facilitation of nitric oxide-evoked [3H]GABA release by removal of hydroxyl radical.
Topics: Animals; Calcium; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Cerebral Cortex; Free Radical Scavengers; gamma-Aminobutyric Acid; Hydroxyl Radical; Mice; Neurons; Nitric Oxide; Thiourea | 1998 |
Involvement of a local fenton reaction in the reciprocal modulation by O2 of the glucagon-dependent activation of the phosphoenolpyruvate carboxykinase gene and the insulin-dependent activation of the glucokinase gene in rat hepatocytes.
Topics: Animals; Biochemistry; Cells, Cultured; Deferoxamine; Enzyme Activation; Glucagon; Glucokinase; Hydroxyl Radical; Image Processing, Computer-Assisted; Insulin; Iron; Liver; Male; Microscopy, Confocal; Oxygen; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Wistar; Rhodamines; Spectrometry, Fluorescence; Thiourea; X-Rays | 1998 |
Ultrastructural study of calcium shift in ischemic/reperfused rat heart under treatment with dimethylthiourea, diltiazem and amiloride.
Topics: Amiloride; Animals; Calcium; Calcium Channel Blockers; Diltiazem; Drug Therapy, Combination; Free Radical Scavengers; Heart; Hydroxyl Radical; In Vitro Techniques; Male; Mitochondria, Heart; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Wistar; Sarcolemma; Sodium-Hydrogen Exchangers; Thiourea | 1998 |
Removal of hydroxyl radical facilitates Ca2+-dependent [3H]GABA release by peroxynitrite.
Topics: Animals; Calcium; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Fetus; Free Radical Scavengers; gamma-Aminobutyric Acid; Hydroxyl Radical; Mannitol; Mice; Neurons; Nitrates; Thiourea; Tritium; Urea; Uric Acid | 1998 |
Uric acid inhibits L-DOPA-CU(II) mediated DNA cleavage.
Topics: Animals; Cattle; Chromosome Breakage; Copper; DNA; DNA Damage; DNA, Superhelical; Dose-Response Relationship, Drug; Hydroxyl Radical; Levodopa; Mannitol; Oxidation-Reduction; Plasmids; Thiourea; Uric Acid; Xanthine | 1998 |
The hydroxyl radical scavengers dimethylsulfoxide and dimethylthiourea protect rats against thioacetamide-induced fulminant hepatic failure.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Dimethyl Sulfoxide; Free Radical Scavengers; Hepatic Encephalopathy; Hydroxyl Radical; L-Lactate Dehydrogenase; Liver; Male; NG-Nitroarginine Methyl Ester; Pentoxifylline; Rats; Rats, Wistar; Thioacetamide; Thiourea | 1999 |
An in vitro study of the hydroxyl radical scavenging property of fluvastatin, and HMG-CoA reductase inhibitor.
Topics: Biotransformation; Fatty Acids, Monounsaturated; Fluvastatin; Free Radical Scavengers; Humans; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Thiourea; Vitamin E | 1999 |
Effects of mannitol and dimethylthiourea on helicobacter pylori-induced IL-8 production in gastric epithelial cells.
Topics: Cell Line; Cytokines; Diuretics, Osmotic; Electrophoresis; Epithelial Cells; Free Radical Scavengers; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Humans; Hydroxyl Radical; Interleukin-8; Lipid Peroxidation; Mannitol; NF-kappa B; Thiourea | 1999 |
Effects of CP-060S, a novel Ca(2+) channel blocker, on oxidative stress in cultured cardiac myocytes.
Topics: Animals; Animals, Newborn; Calcium Channel Blockers; Cell Survival; Cells, Cultured; Cyclic N-Oxides; Diltiazem; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; L-Lactate Dehydrogenase; Myocardium; Oxidants; Oxidative Stress; Phenols; Rats; Rats, Sprague-Dawley; Stereoisomerism; Thiazoles; Thiazolidines; Thiourea | 1999 |
Mechanisms of parenchymal cell death in-vivo after microvascular hemorrhage.
Topics: 2,2'-Dipyridyl; Animals; Cell Death; Free Radical Scavengers; Free Radicals; Hemoglobins; Hemorrhage; Hydrogen Peroxide; Hydroxyl Radical; Iron Chelating Agents; Male; Mesenteric Veins; Mesentery; Microcirculation; Microinjections; Oxidative Stress; Plasma; Rats; Rats, Wistar; Reactive Oxygen Species; Sodium Azide; Thiourea; Venules | 2000 |
Wood smoke-induced airway hyperreactivity in guinea pigs: time course, and role of leukotrienes and hydroxyl radical.
Topics: Animals; Bronchial Hyperreactivity; Bronchodilator Agents; Guinea Pigs; Hydroxyl Radical; Leukotriene Antagonists; Leukotrienes; Male; Neprilysin; Propionates; Quinolines; Smoke; Thiourea; Wood | 2000 |
Transforming growth factor-beta1 increases albumin permeability of isolated rat glomeruli via hydroxyl radicals.
Topics: Animals; Biological Transport; Free Radical Scavengers; Hydroxyl Radical; In Vitro Techniques; Kidney Glomerulus; Male; Proteinuria; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Serum Albumin, Bovine; Superoxide Dismutase; Superoxides; Thiourea; Transforming Growth Factor beta | 2000 |
Effect of dimethylthiourea, a hydroxyl radical scavenger, on cigarette smoke-induced bronchoconstriction in guinea pigs.
Topics: Acetylcholine; Animals; Atropine; Bronchoconstriction; Dose-Response Relationship, Drug; Electric Stimulation; Free Radical Scavengers; Guinea Pigs; Hydroxyl Radical; Insufflation; Lung; Neurokinin A; Pressure; Thiourea; Tobacco Smoke Pollution; Vagus Nerve; Vasodilator Agents | 2000 |
Thioredoxin, a singlet oxygen quencher and hydroxyl radical scavenger: redox independent functions.
Topics: Alanine; Bacterial Proteins; Catalysis; Cyclic N-Oxides; Cysteine; Diuretics, Osmotic; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Escherichia coli; Free Radical Scavengers; Humans; Hydroxyl Radical; Indicators and Reagents; Kinetics; Mannitol; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxidative Stress; Oxygen; Reactive Oxygen Species; Superoxides; Thioredoxins; Thiourea; Time Factors | 2000 |
Detection of dichromate (VI)-induced DNA strand breaks and formation of paramagnetic chromium in multiple mouse organs.
Topics: Animals; Chromium; Deferoxamine; DNA Fragmentation; Electron Spin Resonance Spectroscopy; Electrophoresis; Free Radical Scavengers; Hydroxyl Radical; Iron Chelating Agents; Male; Mice; Potassium Dichromate; Thiourea | 2001 |
Does xanthine oxidase contribute to the hydroxyl radical generation in ischemia and reperfusion of the cochlea?
Topics: Action Potentials; Allopurinol; Animals; Cochlea; Enzyme Inhibitors; Free Radical Scavengers; Guinea Pigs; Hydroxyl Radical; Ischemia; Oxypurinol; Reperfusion Injury; Thiourea; Xanthine Oxidase | 2001 |
Protective effect of thiourea, a hydroxyl-radical scavenger, on curcumin-induced chromosomal aberrations in an in vitro mammalian cell system.
Topics: Animals; Cell Line; CHO Cells; Chromosome Aberrations; Cricetinae; Curcumin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Hydroxyl Radical; Indicators and Reagents; Mutagens; Thiourea | 2001 |
Lead-induced hypertension. III. Increased hydroxyl radical production.
Topics: Animals; Blood Pressure; Free Radical Scavengers; Hydroxyl Radical; Hypertension; Lead; Lipid Peroxides; Male; Rats; Rats, Sprague-Dawley; Thiourea; Tyrosine | 2001 |
Silica-induced activation of c-Jun-NH2-terminal amino kinases, protracted expression of the activator protein-1 proto-oncogene, fra-1, and S-phase alterations are mediated via oxidative stress.
Topics: Animals; Cell Line; DNA; Dose-Response Relationship, Drug; Enzyme Activation; Epithelial Cells; Free Radical Scavengers; Gene Expression Regulation; Hydroxyl Radical; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Oxidative Stress; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins c-fos; Pulmonary Alveoli; RNA, Messenger; S Phase; Silicon Dioxide; Thiourea; Transcription Factor AP-1 | 2001 |
Suppression of Ca2+ influx through L-type voltage-dependent calcium channels by hydroxyl radical in mouse cerebral cortical neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Deferoxamine; Ferrous Compounds; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Ion Channel Gating; Ion Transport; Iron Chelating Agents; Mannitol; Mice; Nerve Tissue Proteins; Neurons; Nifedipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Potassium Chloride; Thiourea | 2001 |
Alleviation of wood smoke-induced lung injury by tachykinin receptor antagonist and hydroxyl radical scavenger in guinea pigs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Disease Models, Animal; Free Radical Scavengers; Guinea Pigs; Hydroxyl Radical; Male; Neprilysin; Receptors, Tachykinin; Respiratory Distress Syndrome; Tachykinins; Thiourea; Wood | 2001 |
Effect of the hydroxyl radical scavenger, dimethylthiourea, on peripheral nerve tissue perfusion, conduction velocity and nociception in experimental diabetes.
Topics: Animals; Diabetes Mellitus, Experimental; Free Radical Scavengers; Hydroxyl Radical; Male; Mechanoreceptors; Neural Conduction; Nociceptors; Oxidative Stress; Peripheral Nerves; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Superior Cervical Ganglion; Thiourea | 2001 |
Oxidation of beta2-glycoprotein I (beta2GPI) by the hydroxyl radical alters phospholipid binding and modulates recognition by anti-beta2GPI autoantibodies.
Topics: Animals; Antibodies, Antiphospholipid; Antibody Affinity; Antibody Specificity; Antigen-Antibody Reactions; Antiphospholipid Syndrome; Autoantibodies; Autoimmune Diseases; beta 2-Glycoprotein I; Cardiolipins; Cattle; Dimerization; Enzyme-Linked Immunosorbent Assay; Epitopes; Free Radical Scavengers; Gamma Rays; Glycoproteins; Humans; Hydroxyl Radical; Immunoglobulin G; Liposomes; Lupus Erythematosus, Systemic; Macromolecular Substances; Mannitol; Oxidation-Reduction; Phospholipids; Structure-Activity Relationship; Thiourea; Thrombophilia; Tryptophan; Water | 2001 |
Cleavage of the fifth component of human complement and release of a split product with C5a-like activity by crystalline silica through free radical generation and kallikrein activation.
Topics: Adult; Chemotaxis; Complement Activation; Complement C5; Complement C5a; Deferoxamine; Female; Free Radical Scavengers; Humans; Hydroxyl Radical; Iron; Iron Chelating Agents; Kallikreins; Male; Middle Aged; Neutrophils; Quartz; Thiourea; Zymosan | 2002 |
Thiourea protects against copper-induced oxidative damage by formation of a redox-inactive thiourea-copper complex.
Topics: Animals; Ascorbic Acid; Cattle; Copper; DNA Damage; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Histidine; Hydrogen Peroxide; Hydroxyl Radical; Oxidation-Reduction; Oxidative Stress; Phenanthrolines; Serum Albumin, Bovine; Thiourea | 2002 |
Role of nitric oxide and free radicals in cardioprotection by blocking Na+/H+ and Na+/Ca2+ exchange in rat heart.
Topics: Animals; Coronary Circulation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radicals; Guanidines; Heart; Heart Rate; Hydroxyl Radical; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Perfusion; Rats; Sodium-Calcium Exchanger; Sodium-Hydrogen Exchangers; Sulfones; Thiourea; Ventricular Function, Left | 2003 |
Ultraviolet-B-induced oxidative DNA base damage in primary normal human epidermal keratinocytes and inhibition by a hydroxyl radical scavenger.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Antineoplastic Agents; Antioxidants; beta Carotene; Cells, Cultured; Deoxyguanosine; Diuretics, Osmotic; DNA Damage; Epidermal Cells; Epidermis; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hydroxyl Radical; Keratinocytes; Mannitol; Oxidation-Reduction; Salicylates; Thiourea; Ultraviolet Rays | 2003 |
Differential roles of hydrogen peroxide and hydroxyl radical in cisplatin-induced cell death in renal proximal tubular epithelial cells.
Topics: Acute Kidney Injury; Animals; Antineoplastic Agents; Apoptosis; Caspases; Cells, Cultured; Cisplatin; Cytochromes c; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Kidney Tubules, Proximal; Necrosis; Rabbits; Reactive Oxygen Species; Thiourea | 2003 |
[The inhibitory effect of Lu-Duo-Wei on carbon disulfide-induced generation of hydroxyl radicals].
Topics: Carbon Disulfide; Drugs, Chinese Herbal; Free Radical Scavengers; Hydroxyl Radical; Luminescent Measurements; Phenanthrolines; Superoxide Dismutase; Thiourea | 2003 |
Neural and hydroxyl radical mechanisms underlying laryngeal airway hyperreactivity induced by laryngeal acid-pepsin insult in anesthetized rats.
Topics: Action Potentials; Ammonia; Animals; Antioxidants; Blood Pressure; Capsaicin; Deferoxamine; Electrophysiology; Free Radical Scavengers; Gastroesophageal Reflux; Hydrogen-Ion Concentration; Hydroxyl Radical; Inflammation; Laryngeal Muscles; Male; Neurons, Afferent; Pepsin A; Rats; Rats, Sprague-Dawley; Respiratory Hypersensitivity; Thiourea | 2006 |
Inhibitory effects of different antioxidants on hyaluronan depolymerization.
Topics: Antioxidants; Hyaluronic Acid; Hydrogen Peroxide; Hydroxyl Radical; Mannitol; Molecular Weight; Polymers; Propofol; Reactive Oxygen Species; Thiourea; Vinca Alkaloids | 2007 |
S-allylcysteine scavenges singlet oxygen and hypochlorous acid and protects LLC-PK(1) cells of potassium dichromate-induced toxicity.
Topics: Animals; Cell Survival; Cysteine; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Hypochlorous Acid; LLC-PK1 Cells; Potassium Dichromate; Pyruvic Acid; Reactive Oxygen Species; Superoxides; Swine; Thioctic Acid; Thiourea | 2007 |
Vascular leakage induced by exposure to arsenic via increased production of NO, hydroxyl radical and peroxynitrite.
Topics: Animals; Arsenites; Blood Vessels; Capillary Permeability; Carbon; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Inhibitors; Evans Blue; Free Radical Scavengers; Guanidines; Hydroxyl Radical; Injections, Intradermal; Injections, Intravenous; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Skin; Sodium Compounds; Thiourea; Tyrosine | 2008 |
Contribution of oxidative damage to antimicrobial lethality.
Topics: 2,2'-Dipyridyl; Anti-Bacterial Agents; Bacterial Proteins; Catalase; Escherichia coli; Escherichia coli Proteins; Hydroxyl Radical; Microbial Sensitivity Tests; Norfloxacin; Oxidative Stress; Superoxide Dismutase; Thiourea | 2009 |
Dimethylthiourea normalizes velocity-dependent, but not force-dependent, index of ventricular performance in diabetic rats: role of myosin heavy chain isozyme.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Cardiovascular Agents; Diabetes Mellitus, Experimental; Elasticity; Free Radical Scavengers; Hemodynamics; Hydroxyl Radical; Male; Myocardial Contraction; Myocardium; Myogenic Regulatory Factors; Myosin Heavy Chains; Oxidative Stress; Protein Isoforms; Rats; Rats, Wistar; Thiourea; Time Factors; Ventricular Dysfunction, Left | 2009 |
Biochemical studies on hemoglobin modified with reactive oxygen species (ROS).
Topics: Antioxidants; Benzoates; Catalase; Electrophoresis, Polyacrylamide Gel; Glutathione; Hemoglobins; Humans; Hydrogen Peroxide; Hydroxyl Radical; Mannitol; Oxidation-Reduction; Reactive Oxygen Species; Sodium Benzoate; Spectrophotometry, Ultraviolet; Superoxides; Thiourea | 2011 |
Endothelial dysfunction and increased responses to renal nerve stimulation in rat kidneys during rhabdomyolysis-induced acute renal failure: role of hydroxyl radical.
Topics: Acetaminophen; Acute Kidney Injury; Animals; Electric Stimulation; Endothelium, Vascular; Female; Free Radical Scavengers; Hydroxyl Radical; In Vitro Techniques; Kidney; Rats; Rats, Wistar; Rhabdomyolysis; Thiourea | 2012 |
Antimicrobial peptide pleurocidin synergizes with antibiotics through hydroxyl radical formation and membrane damage, and exerts antibiofilm activity.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antimicrobial Cationic Peptides; Bacteria; Biofilms; Cell Membrane; Drug Combinations; Drug Synergism; Fish Proteins; Hydroxyl Radical; Microbial Sensitivity Tests; Microbial Viability; NADP; Thiourea | 2012 |
Role of TRPV1 and P2X receptors in the activation of lung vagal C-fiber afferents by inhaled cigarette smoke in rats.
Topics: Animals; Capsaicin; Cholinergic Fibers; Humans; Hydroxyl Radical; Pyridoxal Phosphate; Rats; Reactive Oxygen Species; Receptors, Nicotinic; Receptors, Purinergic P2X; Smoke; Smoking; Thiourea; TRPV Cation Channels | 2013 |
Lethal hydroxyl radical accumulation by a lactococcal bacteriocin, lacticin Q.
Topics: Anti-Bacterial Agents; Bacteriocins; Cell Membrane; Hydroxyl Radical; Lactococcus lactis; Membrane Lipids; Membrane Potentials; Microbial Sensitivity Tests; Microbial Viability; Pediococcus; Thiourea | 2013 |
Rifampin induces hydroxyl radical formation in Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Bacterial Proteins; Catalase; Cyclic N-Oxides; DNA-Directed RNA Polymerases; Electron Spin Resonance Spectroscopy; Hydroxyl Radical; Mycobacterium tuberculosis; Oxidative Stress; Pentetic Acid; Protein Binding; Rifampin; Spin Labels; Superoxide Dismutase; Superoxides; Thiourea | 2014 |
Evaluation of Hydroxyl Radical Diffusion and Acidified Thiourea as a Scavenger during Intracoronal Bleaching.
Topics: Bicuspid; Borates; Chromatography, High Pressure Liquid; Diffusion; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hydroxyl Radical; In Vitro Techniques; Surface Properties; Thiourea; Tooth Bleaching | 2016 |
Reactive oxygen species affect spinal cell type-specific synaptic plasticity in a model of neuropathic pain.
Topics: Afferent Pathways; Animals; Cyclic N-Oxides; Disease Models, Animal; Free Radical Scavengers; GABA Agents; GABAergic Neurons; Glutamate Decarboxylase; Hydroxyl Radical; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuralgia; Neuronal Plasticity; Reactive Oxygen Species; Spin Labels; Spinal Nerves; Superoxides; Synaptic Potentials; Thiourea | 2017 |
Detection and scavenging of hydroxyl radical via D-phenylalanine hydroxylation in human fluids.
Topics: Adult; Chocolate; Diet; Female; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hydroxyl Radical; Hydroxylation; Iron; Male; Middle Aged; Milk, Human; Phenylalanine; Pregnancy; Reproducibility of Results; Semen; Thiourea; Tyrosine; Young Adult | 2018 |
Contributions of reactive oxygen species, oxidative DNA damage and glutathione depletion to the sensitivity of Acinetobacter baumannii to 2-(2-nitrovinyl) furan.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Antioxidants; Bacterial Proteins; Catalase; DNA Damage; Furans; Glutathione; Hydrogen Peroxide; Hydroxyl Radical; Microbial Sensitivity Tests; NAD; NADH Dehydrogenase; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Rec A Recombinases; Superoxide Dismutase; Superoxides; Thiourea; Vinyl Compounds | 2019 |
Heterogeneity of ROS levels in antibiotic-exposed mycobacterial subpopulations confers differential susceptibility.
Topics: Anti-Bacterial Agents; Cyclic N-Oxides; Hydrogen Peroxide; Hydroxyl Radical; Isoniazid; Microbial Viability; Models, Biological; Mycobacterium smegmatis; Oxidative Stress; Phenotype; Reactive Oxygen Species; Rifampin; Spin Labels; Superoxides; Thiourea | 2019 |