hydroxyl radical has been researched along with thioctic acid in 18 studies
Studies (hydroxyl radical) | Trials (hydroxyl radical) | Recent Studies (post-2010) (hydroxyl radical) | Studies (thioctic acid) | Trials (thioctic acid) | Recent Studies (post-2010) (thioctic acid) |
---|---|---|---|---|---|
10,147 | 26 | 3,657 | 4,628 | 322 | 1,947 |
Protein | Taxonomy | hydroxyl radical (IC50) | thioctic acid (IC50) |
---|---|---|---|
Ubiquitin-like modifier activating enzyme 2 | Homo sapiens (human) | 2.68 | |
SUMO1 activating enzyme subunit 1 | Homo sapiens (human) | 2.68 | |
hexokinase | Trypanosoma brucei brucei TREU927 | 0.2008 | |
SUMO-conjugating enzyme UBC9 | Homo sapiens (human) | 2.68 | |
eukaryotic translation initiation factor 4 gamma 1 isoform 4 | Homo sapiens (human) | 16.56 | |
eukaryotic translation initiation factor 4E isoform 1 | Mus musculus (house mouse) | 16.56 | |
Vif | Human immunodeficiency virus 1 | 7.67 | |
Tat | Human immunodeficiency virus 1 | 5.891 | |
DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | 7.67 | |
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase | Mycobacterium tuberculosis H37Rv | 3.91 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 4 (22.22) | 18.2507 |
2000's | 12 (66.67) | 29.6817 |
2010's | 2 (11.11) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Packer, L; Suzuki, YJ; Tsuchiya, M | 1 |
Packer, L; Tritschler, HJ; Witt, EH | 1 |
Han, D; Matsugo, S; Packer, L; Trischler, HJ; Yan, LJ | 1 |
Chen, F; Rojanasakul, Y; Shi, X; Ye, J; Zhang, X | 1 |
Arivazhagan, P; Panneerselvam, C; Ramanathan, K | 1 |
Choi, DW; Choi, EH; Dugan, LL; Kim-Han, JS; Sheline, CT | 1 |
Brunk, UT; Eaton, JW; Persson, HL; Tirosh, O; Yu, Z | 1 |
Chow, CK; Gaetke, LM | 1 |
Avila, E; Díaz-Cruz, A; Guinzberg, R; Piña, E; Ramírez, G; Serret, M | 1 |
Chang, CP; Huang, WT; Lin, MT | 1 |
Afantitis, A; Athanasellis, G; Bouloumbasi, D; Detsi, A; Hadjipavlou-Litina, DJ; Igglessi-Markopoulou, O; Kontogiorgis, C; Koufaki, M; Melagraki, G; Prousis, KC | 1 |
Barrera, D; Maldonado, PD; Medina-Campos, ON; Mendoza-Patiño, N; Pedraza-Chaverri, J; Rocha, D; Segoviano-Murillo, S | 1 |
Bryla, J; Dudziak, M; Malinska, D; Szymanski, K; Winiarska, K | 1 |
Arul, V; Baraneedharan, U; Davis, GD; Jayakumar, R; Jesudason, EP; Kumar, MS; Masilamoni, JG; Paul, SF; Sakthivelu, IV | 1 |
Delemasure, S; Ghibu, S; Mogosan, C; Muresan, A; Richard, C; Vergely, C | 1 |
Jia, Z; Li, Y; Misra, BR; Misra, HP; Vitto, MJ; Zhu, H | 1 |
Banerjee, S; Baxi, D; Joshi, N; Mukherjee, R; Ramachandran, AV; Singh, PK | 1 |
Brizzolari, A; Campisi, GM; Foti, MC; Razzaghi-Asl, N; Santaniello, E; Saso, L | 1 |
3 review(s) available for hydroxyl radical and thioctic acid
Article | Year |
---|---|
alpha-Lipoic acid as a biological antioxidant.
Topics: Animals; Antioxidants; Disease; Humans; Hydroxyl Radical; Molecular Structure; Reactive Oxygen Species; Thioctic Acid | 1995 |
Copper toxicity, oxidative stress, and antioxidant nutrients.
Topics: Animals; Antioxidants; Ascorbic Acid; beta Carotene; Copper; Flavonoids; Humans; Hydroxyl Radical; Oxidative Stress; Phenols; Polymers; Polyphenols; Thioctic Acid; Vitamin E; Zinc | 2003 |
[An endogenous dithiol with antioxidant properties: alpha-lipoic acid, potential uses in cardiovascular diseases].
Topics: 8,11,14-Eicosatrienoic Acid; Animal Experimentation; Animals; Antioxidants; Cardiovascular Diseases; Diabetes Mellitus; Endothelium, Vascular; Free Radical Scavengers; Humans; Hydroxyl Radical; Insulin Resistance; Neurodegenerative Diseases; Oxidation-Reduction; Randomized Controlled Trials as Topic; Rats; Thioctic Acid; Toluene; Vitamin B Complex | 2008 |
15 other study(ies) available for hydroxyl radical and thioctic acid
Article | Year |
---|---|
Thioctic acid and dihydrolipoic acid are novel antioxidants which interact with reactive oxygen species.
Topics: Antioxidants; Binding, Competitive; Electron Spin Resonance Spectroscopy; Epinephrine; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Kinetics; Oxygen; Superoxides; Thioctic Acid | 1991 |
Elucidation of antioxidant activity of alpha-lipoic acid toward hydroxyl radical.
Topics: Antioxidants; Apolipoproteins B; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Humans; Hydroxyl Radical; Kinetics; Naphthalenes; Radiation-Sensitizing Agents; Salicylates; Salicylic Acid; Serum Albumin, Bovine; Spin Labels; Thioctic Acid; Ultraviolet Rays | 1995 |
One-electron reduction of chromium(VI) by alpha-lipoic acid and related hydroxyl radical generation, dG hydroxylation and nuclear transcription factor-kappaB activation.
Topics: Antioxidants; Carcinogens; Chromium; Deoxyguanosine; DNA-Binding Proteins; Electron Spin Resonance Spectroscopy; Humans; Hydroxyl Radical; Hydroxylation; NF-kappa B; Oxidation-Reduction; Thioctic Acid; Tumor Cells, Cultured | 1997 |
Effect of DL-alpha-lipoic acid on glutathione metabolic enzymes in aged rats.
Topics: Aging; Animals; Antioxidants; Dietary Supplements; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Hydroxyl Radical; Kidney; Liver; Male; Rats; Rats, Wistar; Thioctic Acid | 2001 |
Cofactors of mitochondrial enzymes attenuate copper-induced death in vitro and in vivo.
Topics: Animals; Apoptosis; Cell Death; Cells, Cultured; Cerebral Cortex; Copper; Embryo, Mammalian; Free Radical Scavengers; Hydroxyl Radical; Longevity; Mice; Neurons; Neuroprotective Agents; Rats; Rats, Long-Evans; Thiamine; Thioctic Acid | 2002 |
Prevention of oxidant-induced cell death by lysosomotropic iron chelators.
Topics: Animals; Antioxidants; Apoptosis; Caspases; Cells, Cultured; Deferoxamine; Electron Spin Resonance Spectroscopy; Enzyme Activation; Free Radicals; Hydrogen Peroxide; Hydroxyl Radical; Iron; Iron Chelating Agents; Lysosomes; Macrophages; Membrane Potentials; Mice; Mitochondria; Oxidation-Reduction; Oxidative Stress; Thioctic Acid | 2003 |
Prophylactic action of lipoic acid on oxidative stress and growth performance in broilers at risk of developing ascites syndrome.
Topics: Animals; Ascites; Chickens; Dietary Supplements; Dose-Response Relationship, Drug; Eating; Glutathione; Hydroxyl Radical; Oxidative Stress; Oxygen; Poultry Diseases; Random Allocation; Risk Factors; Syndrome; Thiobarbituric Acid Reactive Substances; Thioctic Acid | 2003 |
An NMDA receptor-dependent hydroxyl radical pathway in the rabbit hypothalamus may mediate lipopolysaccharide fever.
Topics: Acetylcysteine; Analgesics, Non-Narcotic; Animals; Antioxidants; Body Temperature; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Fever; Hydroxybenzoates; Hydroxyl Radical; Isoquinolines; Lipopolysaccharides; Male; Rabbits; Receptors, N-Methyl-D-Aspartate; Thioctic Acid | 2006 |
Design and synthesis of novel quinolinone-3-aminoamides and their alpha-lipoic acid adducts as antioxidant and anti-inflammatory agents.
Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Biphenyl Compounds; Carrageenan; Dimethyl Sulfoxide; Edema; Female; Hydrazines; Hydroxyl Radical; Lipoxygenase Inhibitors; Male; Oxidation-Reduction; Picrates; Quinolones; Rats; Rats, Inbred F344; Structure-Activity Relationship; Thioctic Acid | 2007 |
S-allylcysteine scavenges singlet oxygen and hypochlorous acid and protects LLC-PK(1) cells of potassium dichromate-induced toxicity.
Topics: Animals; Cell Survival; Cysteine; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Hypochlorous Acid; LLC-PK1 Cells; Potassium Dichromate; Pyruvic Acid; Reactive Oxygen Species; Superoxides; Swine; Thioctic Acid; Thiourea | 2007 |
Lipoic acid ameliorates oxidative stress and renal injury in alloxan diabetic rabbits.
Topics: Animals; Antioxidants; Blood Glucose; Creatine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glutathione; Hydroxyl Radical; Kidney Cortex; Liver; Oxidation-Reduction; Oxidative Stress; Rabbits; Thioctic Acid; Time Factors; Urea | 2008 |
Radioprotective effect of DL-alpha-lipoic acid on mice skin fibroblasts.
Topics: Animals; Antioxidants; Catalase; Cells, Cultured; Electron Spin Resonance Spectroscopy; Fibroblasts; Gamma Rays; Glutathione Reductase; Hydroxyl Radical; Interleukin-1beta; Lipid Peroxidation; Mice; Nitric Oxide; Radiation-Protective Agents; Reactive Oxygen Species; Skin; Superoxide Dismutase; Thioctic Acid | 2009 |
Alpha-lipoic acid potently inhibits peroxynitrite-mediated DNA strand breakage and hydroxyl radical formation: implications for the neuroprotective effects of alpha-lipoic acid.
Topics: Animals; Antioxidants; DNA Breaks, Double-Stranded; Electron Spin Resonance Spectroscopy; Humans; Hydroxyl Radical; Molsidomine; Neuroprotective Agents; Nitric Oxide Donors; Oxidative Stress; Oxygen Consumption; Peroxynitrous Acid; Thioctic Acid | 2009 |
A combination of melatonin and alpha lipoic acid has greater cardioprotective effect than either of them singly against cadmium-induced oxidative damage.
Topics: Animals; Antioxidants; Ascorbic Acid; Biomarkers; Cadmium Chloride; Drug Synergism; Drug Therapy, Combination; Enzymes; Female; Glutathione; Heart Diseases; Hydrogen Peroxide; Hydroxyl Radical; Lipid Peroxidation; Malondialdehyde; Melatonin; Metallothionein; Myocardium; Oxidative Stress; Rats; Thioctic Acid; Vitamin E | 2011 |
Effect of organic co-solvents in the evaluation of the hydroxyl radical scavenging activity by the 2-deoxyribose degradation assay: The paradigmatic case of α-lipoic acid.
Topics: Acetonitriles; Deoxyribose; Free Radical Scavengers; Hydroxyl Radical; Organic Chemicals; Solubility; Solvents; Thioctic Acid | 2017 |