Page last updated: 2024-09-04

hydroxyl radical and resveratrol

hydroxyl radical has been researched along with resveratrol in 23 studies

Compound Research Comparison

Studies
(hydroxyl radical)
Trials
(hydroxyl radical)
Recent Studies (post-2010)
(hydroxyl radical)
Studies
(resveratrol)
Trials
(resveratrol)
Recent Studies (post-2010) (resveratrol)
10,147263,65710,9312417,998

Protein Interaction Comparison

ProteinTaxonomyhydroxyl radical (IC50)resveratrol (IC50)
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
Chain A, Leukotriene A-4 hydrolaseHomo sapiens (human)212
M18 aspartyl aminopeptidasePlasmodium falciparum 3D72.242
VifHuman immunodeficiency virus 125.31
DNA dC->dU-editing enzyme APOBEC-3G isoform 1Homo sapiens (human)25.31
Transient receptor potential cation channel subfamily A member 1Homo sapiens (human)0.75
Amyloid-beta precursor proteinHomo sapiens (human)2.6
Cytochrome P450 1A2Homo sapiens (human)3
Prostaglandin G/H synthase 1Ovis aries (sheep)2.025
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)2.312
Luciferin 4-monooxygenasePhotinus pyralis (common eastern firefly)0.0589
Cytochrome P450 3A4Homo sapiens (human)0.6
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.685
DNA polymerase alpha catalytic subunitHomo sapiens (human)3.3
Polyunsaturated fatty acid 5-lipoxygenaseHomo sapiens (human)4.9
AromataseHomo sapiens (human)0.96
Cytochrome P450 2C9 Homo sapiens (human)7
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.685
TyrosinaseHomo sapiens (human)5.35
Ribosyldihydronicotinamide dehydrogenase [quinone]Homo sapiens (human)1.3972
Nuclear factor NF-kappa-B p105 subunitHomo sapiens (human)2.5
Amine oxidase [flavin-containing] AHomo sapiens (human)2.4945
Prostaglandin G/H synthase 1Homo sapiens (human)0.8517
Sodium-dependent noradrenaline transporter Homo sapiens (human)2.312
Amine oxidase [flavin-containing] BHomo sapiens (human)5.01
Dipeptidyl peptidase 4Homo sapiens (human)0.0006
Cytochrome P450 2C19Homo sapiens (human)3
Prostaglandin G/H synthase 2Homo sapiens (human)1.672
Prostaglandin G/H synthase 2Ovis aries (sheep)3.49
Nuclear factor NF-kappa-B p100 subunit Homo sapiens (human)2.5
Transcription factor p65Homo sapiens (human)2.5
Cytochrome P450 1B1Homo sapiens (human)1.4
Transient receptor potential cation channel subfamily A member 1Rattus norvegicus (Norway rat)1.63
large T antigenBetapolyomavirus macacae26.2

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (8.70)18.2507
2000's12 (52.17)29.6817
2010's9 (39.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lariccia, J; Nair, MG; Turrens, JF1
Fukuhara, K; Miyata, N1
Bagchi, D; Das, DK; Maulik, G; Sato, M1
Brundin, P; Burkitt, MJ; Emgard, M; Karlsson, J1
Burkitt, MJ; Duncan, J1
Beebe, SJ; Elliott, MS; Morris, GZ; Williams, RL1
Chang, EJ; Cho, SH; Choi, SW; Chung, SK; Kim, HJ; Park, HD1
Andreazza, AC; Salvador, M; Soares, DG1
Kerem, Z; Regev-Shoshani, G; Shoseyov, O1
Bertelli, A; Falchi, M; Morelli, R1
Fukuhara, K; Fukuzumi, S; Ikota, N; Imai, K; Miyata, N; Mochizuki, M; Nagakawa, M; Nakanishi, I; Ohkubo, K; Okuda, H; Ozawa, T; Urano, S1
Beaudeux, JL; Bonnefont-Rousselot, D; Camont, L; Couturier, M; Gardés-Albert, M; Jore, D; Legrand, A; Rhayem, Y; Thérond, P1
Caruso, F; Opazo, C; Rossi, M; Salciccioli, J1
Chou, DS; Hsiao, G; Lin, KH; Sheu, JR; Shih, CM1
Li, L; Liu, YZ; Luo, XJ; Peng, J; Tan, N; Xiang, DX; Yuan, Q; Zhang, YS1
Chen, G; Liu, X; Ma, C; Mou, Y; Pan, L; Wu, C; Yan, Y; Yang, J; Zhao, Y1
Bonnefont-Rousselot, D; Camont, L; Collin, F; Couturier, M; Gardès-Albert, M; Jore, D; Thérond, P1
Alvarez-Idaboy, JR; Iuga, C; Russo, N1
Chen, CH; Han, RM; Lai, W; Li, DD; Liang, R; Skibsted, LH; Zhang, JP1
Huang, L; Jia, X; Li, J; Li, X; Mao, F; Miao, H; Sun, Y; Yan, J1
Cho, EJ; Jang, M; Piao, XL1
Han, J; Hayashi, K; Okamoto, Y; Suga, K; Umakoshi, H1
Oh, WY; Shahidi, F1

Other Studies

23 other study(ies) available for hydroxyl radical and resveratrol

ArticleYear
Resveratrol has no effect on lipoprotein profile and does not prevent peroxidation of serum lipids in normal rats.
    Free radical research, 1997, Volume: 27, Issue:6

    Topics: Animals; Antioxidants; Female; Hydroxyl Radical; Lipid Peroxidation; Lipids; Lipoproteins; Rats; Reference Values; Resveratrol; Stilbenes

1997
Resveratrol as a new type of DNA-cleaving agent.
    Bioorganic & medicinal chemistry letters, 1998, Nov-17, Volume: 8, Issue:22

    Topics: Antineoplastic Agents, Phytogenic; Copper; DNA; DNA Damage; Hydroxyl Radical; Resveratrol; Stilbenes

1998
Myocardial protection by protykin, a novel extract of trans-resveratrol and emodin.
    Free radical research, 2000, Volume: 32, Issue:2

    Topics: Animals; Antioxidants; Blood Pressure; Coronary Vessels; Emodin; Fluoresceins; Free Radical Scavengers; Gamma Rays; Hydroxyl Radical; Male; Malondialdehyde; Myocardial Infarction; Myocardial Ischemia; Oxidative Stress; Peroxides; Polygonaceae; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Stilbenes

2000
trans-resveratrol protects embryonic mesencephalic cells from tert-butyl hydroperoxide: electron paramagnetic resonance spin trapping evidence for a radical scavenging mechanism.
    Journal of neurochemistry, 2000, Volume: 75, Issue:1

    Topics: Animals; Antioxidants; Coumarins; Electron Spin Resonance Spectroscopy; Female; Free Radical Scavengers; Free Radicals; Hydroxyl Radical; L-Lactate Dehydrogenase; Mesencephalon; Pregnancy; Rats; Rats, Sprague-Dawley; Resveratrol; Spin Labels; Stilbenes; tert-Butylhydroperoxide

2000
Effects of trans-resveratrol on copper-dependent hydroxyl-radical formation and DNA damage: evidence for hydroxyl-radical scavenging and a novel, glutathione-sparing mechanism of action.
    Archives of biochemistry and biophysics, 2000, Sep-15, Volume: 381, Issue:2

    Topics: Antioxidants; Ascorbic Acid; Copper; DNA; DNA Damage; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Glutathione; Humans; Hydrogen Peroxide; Hydroxyl Radical; In Vitro Techniques; Resveratrol; Stilbenes

2000
Resveratrol induces apoptosis in LNCaP cells and requires hydroxyl groups to decrease viability in LNCaP and DU 145 cells.
    The Prostate, 2002, Sep-01, Volume: 52, Issue:4

    Topics: Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Apoptosis; Caspases; Cell Survival; Diethylstilbestrol; Estrogens, Non-Steroidal; Humans; Hydroxyl Radical; Male; Prostatic Neoplasms; Resveratrol; Stilbenes; Tumor Cells, Cultured

2002
Antioxidative activity of resveratrol and its derivatives isolated from seeds of Paeonia lactiflora.
    Bioscience, biotechnology, and biochemistry, 2002, Volume: 66, Issue:9

    Topics: Animals; Antioxidants; Deoxyribose; Hepatocytes; Hydroxyl Radical; Lipid Peroxidation; Microsomes, Liver; Molecular Structure; Paeonia; Rats; Resveratrol; Seeds; Stilbenes

2002
Sequestering ability of butylated hydroxytoluene, propyl gallate, resveratrol, and vitamins C and E against ABTS, DPPH, and hydroxyl free radicals in chemical and biological systems.
    Journal of agricultural and food chemistry, 2003, Feb-12, Volume: 51, Issue:4

    Topics: Antioxidants; Apomorphine; Ascorbic Acid; Benzothiazoles; beta Carotene; Biphenyl Compounds; Butylated Hydroxytoluene; Hydrogen Peroxide; Hydroxyl Radical; Oxidation-Reduction; Paraquat; Picrates; Propyl Gallate; Resveratrol; Saccharomyces cerevisiae; Stilbenes; Sulfonic Acids; Vitamin E

2003
Influence of lipophilicity on the interactions of hydroxy stilbenes with cytochrome P450 3A4.
    Biochemical and biophysical research communications, 2004, Oct-15, Volume: 323, Issue:2

    Topics: Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Activation; Enzyme Inhibitors; Enzyme Stability; Hydroxyl Radical; Kinetics; Oxidation-Reduction; Protein Binding; Resveratrol; Solvents; Stilbenes; Substrate Specificity; Testosterone

2004
Effects of uvalino, a new autochthonous wine, on the inhibition of the production of hydroxyl radicals.
    Drugs under experimental and clinical research, 2004, Volume: 30, Issue:4

    Topics: Antioxidants; Cyclic N-Oxides; Drug Evaluation, Preclinical; Electron Spin Resonance Spectroscopy; Hydrogen Peroxide; Hydroxyl Radical; Iron; Medicine, Traditional; Resveratrol; Spin Trapping; Stilbenes; Wine

2004
Structural basis for DNA-cleaving activity of resveratrol in the presence of Cu(II).
    Bioorganic & medicinal chemistry, 2006, Mar-01, Volume: 14, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Binding Sites; Cations, Divalent; Copper; DNA; DNA Damage; Hydroxyl Radical; Reactive Oxygen Species; Resveratrol; Stilbenes; Structure-Activity Relationship

2006
Chain-breaking activity of resveratrol and piceatannol in a linoleate micellar model.
    Chemistry and physics of lipids, 2008, Volume: 155, Issue:1

    Topics: Chemistry, Physical; Chromatography, High Pressure Liquid; Dose-Response Relationship, Radiation; Free Radical Scavengers; Hydrogen-Ion Concentration; Hydroxyl Radical; Linoleic Acid; Lipid Peroxidation; Micelles; Models, Chemical; Oxidation-Reduction; Oxygen; Resveratrol; Stilbenes

2008
Crystal and molecular structure of piceatannol; scavenging features of resveratrol and piceatannol on hydroxyl and peroxyl radicals and docking with transthyretin.
    Journal of agricultural and food chemistry, 2008, Nov-26, Volume: 56, Issue:22

    Topics: Crystallization; Crystallography, X-Ray; Free Radical Scavengers; Hydrogen Bonding; Hydroxyl Radical; Molecular Structure; Peroxides; Prealbumin; Resveratrol; Stilbenes

2008
Mechanisms of resveratrol-induced platelet apoptosis.
    Cardiovascular research, 2009, Aug-01, Volume: 83, Issue:3

    Topics: Actins; Apoptosis; bcl-2-Associated X Protein; BH3 Interacting Domain Death Agonist Protein; Blood Platelets; Caspase 3; Caspase 8; Caspase 9; Caspase Inhibitors; Cell Survival; Cysteine Proteinase Inhibitors; Cytochromes c; Dose-Response Relationship, Drug; Gelsolin; Humans; Hydroxyl Radical; Membrane Potential, Mitochondrial; Mitochondria; Oligopeptides; P-Selectin; Phosphatidylserines; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Transport; Resveratrol; Signal Transduction; Stilbenes; Time Factors

2009
The role of the DDAH-ADMA pathway in the protective effect of resveratrol analog BTM-0512 on gastric mucosal injury.
    Canadian journal of physiology and pharmacology, 2010, Volume: 88, Issue:5

    Topics: Amidohydrolases; Animals; Anti-Ulcer Agents; Arginine; Disease Models, Animal; Ethanol; Hydroxyl Radical; Male; Molecular Structure; Nitric Oxide; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Stomach Ulcer; Superoxides

2010
Protection of resveratrol and its analogues against ethanol-induced oxidative DNA damage in human peripheral lymphocytes.
    Mutation research, 2011, Apr-03, Volume: 721, Issue:2

    Topics: Antioxidants; Cell Survival; Cells, Cultured; DNA Damage; DNA Repair; Ethanol; Female; Humans; Hydroxyl Radical; Lymphocytes; Male; Oxidation-Reduction; Resveratrol; Stilbenes

2011
Radical-induced oxidation of trans-resveratrol.
    Biochimie, 2012, Volume: 94, Issue:3

    Topics: Gamma Rays; Hydroxyl Radical; Oxidation-Reduction; Reactive Oxygen Species; Resveratrol; Stilbenes

2012
Antioxidant activity of trans-resveratrol toward hydroxyl and hydroperoxyl radicals: a quantum chemical and computational kinetics study.
    The Journal of organic chemistry, 2012, Apr-20, Volume: 77, Issue:8

    Topics: Antioxidants; Free Radical Scavengers; Hydroxyl Radical; Kinetics; Molecular Structure; Oxidation-Reduction; Peroxides; Quantum Theory; Resveratrol; Stilbenes; Water

2012
Hydroxyl radical reaction with trans-resveratrol: initial carbon radical adduct formation followed by rearrangement to phenoxyl radical.
    The journal of physical chemistry. B, 2012, Jun-21, Volume: 116, Issue:24

    Topics: Carbon; Electron Transport; Hydroxyl Radical; Isomerism; Models, Molecular; Phenols; Photolysis; Protons; Quantum Theory; Resveratrol; Spectrophotometry; Stilbenes

2012
New multi-target-directed small molecules against Alzheimer's disease: a combination of resveratrol and clioquinol.
    Organic & biomolecular chemistry, 2014, Aug-21, Volume: 12, Issue:31

    Topics: Absorption, Physiological; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Blood-Brain Barrier; Chelating Agents; Clioquinol; Copper; Drug Design; Hydroxyl Radical; Mice; Oxidation-Reduction; Permeability; Protein Aggregates; Resveratrol; Small Molecule Libraries; Spectrophotometry, Ultraviolet; Stilbenes

2014
Protective effects of resveratrol oligomers from Vitis amurensis against sodium nitroprusside-induced neurotoxicity in human neuroblastoma SH-SY5Y cells.
    Archives of pharmacal research, 2015, Volume: 38, Issue:6

    Topics: Antioxidants; Benzofurans; Cell Line; DNA Fragmentation; Free Radical Scavengers; Humans; Hydroxyl Radical; Neuroprotective Agents; Neurotoxicity Syndromes; Nitric Oxide; Nitroprusside; Phenols; Plant Roots; Reactive Nitrogen Species; Resveratrol; Stilbenes; Vitis

2015
Multi-Level Characterization of the Membrane Properties of Resveratrol-Incorporated Liposomes.
    The journal of physical chemistry. B, 2017, 04-27, Volume: 121, Issue:16

    Topics: Antioxidants; Cell Membrane; Hydroxyl Radical; Lipid Peroxidation; Liposomes; Membrane Fluidity; Resveratrol; Stilbenes

2017
Antioxidant activity of resveratrol ester derivatives in food and biological model systems.
    Food chemistry, 2018, Sep-30, Volume: 261

    Topics: Animals; Antioxidants; Cattle; Copper; Esterification; Esters; Food Additives; Free Radical Scavengers; Hydroxyl Radical; Lipoproteins, LDL; Meat; Models, Biological; Oxidation-Reduction; Resveratrol; Stilbenes

2018