hydroxyl radical has been researched along with pergolide in 4 studies
| Studies (hydroxyl radical) | Trials (hydroxyl radical) | Recent Studies (post-2010) (hydroxyl radical) | Studies (pergolide) | Trials (pergolide) | Recent Studies (post-2010) (pergolide) |
|---|---|---|---|---|---|
| 10,147 | 26 | 3,657 | 845 | 123 | 87 |
| Protein | Taxonomy | hydroxyl radical (IC50) | pergolide (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.379 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.385 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.264 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.2 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.111 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.385 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.064 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 1.41 | |
| D | Rattus norvegicus (Norway rat) | 0.0031 | |
| D(3) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0031 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.2 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.041 | |
| D(2) dopamine receptor | Bos taurus (cattle) | 0.0603 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 0.679 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.041 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.041 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 1.513 | |
| D(1B) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0031 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.014 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.379 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.2 | |
| 5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | 0.385 | |
| D(4) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0031 | |
| 5-hydroxytryptamine receptor 1F | Rattus norvegicus (Norway rat) | 0.385 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.385 | |
| 5-hydroxytryptamine receptor 6 | Rattus norvegicus (Norway rat) | 0.385 | |
| 5-hydroxytryptamine receptor 7 | Rattus norvegicus (Norway rat) | 0.385 | |
| 5-hydroxytryptamine receptor 5A | Rattus norvegicus (Norway rat) | 0.385 | |
| 5-hydroxytryptamine receptor 5B | Rattus norvegicus (Norway rat) | 0.385 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.0054 | |
| 5-hydroxytryptamine receptor 3A | Rattus norvegicus (Norway rat) | 0.385 | |
| Alpha-synuclein | Homo sapiens (human) | 7.9 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.076 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 0.039 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0031 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 0.1202 | |
| 5-hydroxytryptamine receptor 4 | Rattus norvegicus (Norway rat) | 0.385 | |
| D | Bos taurus (cattle) | 0.0603 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.385 | |
| 5-hydroxytryptamine receptor 3B | Rattus norvegicus (Norway rat) | 0.385 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Asanuma, M; Gómez-Vargas, M; Iwata, E; Kondo, Y; Nishibayashi-Asanuma, S; Ogawa, N | 1 |
| Blunt, SB; Opacka-Juffry, J; Wilson, AW | 1 |
| Chuda, M; Hayabara, T; Ihara, Y; Kuroda, S | 1 |
| Ferger, B; Mierau, J; Teismann, P | 1 |
4 other study(ies) available for hydroxyl radical and pergolide
| Article | Year |
|---|---|
Pergolide scavenges both hydroxyl and nitric oxide free radicals in vitro and inhibits lipid peroxidation in different regions of the rat brain.
Topics: Animals; Benzoates; Brain Chemistry; Corpus Striatum; Cyclic N-Oxides; Dopamine Agonists; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Gyrus Cinguli; Hydroxyl Radical; Imidazoles; Lipid Peroxidation; Male; Nitric Oxide; Nucleus Accumbens; Oxidation-Reduction; Pergolide; Phospholipids; Rats; Rats, Sprague-Dawley; Substantia Nigra; Telencephalon | 1998 |
Effects of pergolide treatment on in vivo hydroxyl free radical formation during infusion of 6-hydroxydopamine in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Chromatography, High Pressure Liquid; Dopamine; Free Radical Scavengers; Hydroxyl Radical; Injections; Male; Neostriatum; Oxidopamine; Pergolide; Rats; Rats, Sprague-Dawley; Sympatholytics | 1998 |
Hydroxyl radical and superoxide dismutase in blood of patients with Parkinson's disease: relationship to clinical data.
Topics: Age Factors; Age of Onset; Aged; Antiparkinson Agents; Bromocriptine; Disease Progression; Erythrocytes; Humans; Hydroxyl Radical; Levodopa; Middle Aged; Multiple System Atrophy; Parkinson Disease; Pergolide; Severity of Illness Index; Statistics as Topic; Superoxide Dismutase; Time Factors | 1999 |
The dopamine agonist pramipexole scavenges hydroxyl free radicals induced by striatal application of 6-hydroxydopamine in rats: an in vivo microdialysis study.
Topics: Adrenergic Agents; Animals; Benzothiazoles; Corpus Striatum; Dopamine; Dopamine Agonists; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Oxidopamine; Pergolide; Pramipexole; Rats; Rats, Wistar; Thiazoles | 2000 |