hydroxyl radical has been researched along with oligonucleotides in 34 studies
| Studies (hydroxyl radical) | Trials (hydroxyl radical) | Recent Studies (post-2010) (hydroxyl radical) | Studies (oligonucleotides) | Trials (oligonucleotides) | Recent Studies (post-2010) (oligonucleotides) |
|---|---|---|---|---|---|
| 10,147 | 26 | 3,657 | 23,128 | 245 | 7,331 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (14.71) | 18.2507 |
| 2000's | 23 (67.65) | 29.6817 |
| 2010's | 6 (17.65) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ding, ZM; Hurley, LH | 1 |
| Dikalov, SI; Frolova, EI; Godovikova, TS; Rumyantseva, GV; Sergejev, DS; Weiner, LM; Zarytova, VF | 1 |
| Iwai, S; Kataoka, S; Nakamura, H; Ohtsuka, E; Wakasa, M | 1 |
| Herschlag, D; Khosla, M; Narlikar, GJ; Usman, N | 1 |
| Geacintov, NE; Jelinsky, S; Liu, T; Loechler, EL; Shukla, R | 1 |
| Joseph, S; Noller, HF | 1 |
| Bernhard, WA; Debije, MG; Strickler, MD | 1 |
| Barone, F; Cellai, L; Matzeu, M; Mazzei, F; Pedone, F | 1 |
| Beveridge, DL; Liu, Y | 1 |
| Chakrabarti, S; Makrigiorgos, GM; Maulik, G; Price, BD; Tetradis, S; Zhang, Y | 1 |
| Burdzy, A; Noyes, KT; Sowers, LC; Valinluck, V | 1 |
| Gorenstein, DG; Jerina, DM; Luxon, BA; Rice, JS; Sayer, JM; Shah, JH; Thiviyanathan, V; Volk, DE; Yagi, H; Yeh, HJ | 1 |
| Kamaike, K; Kawashima, E; Kayama, Y; Namiki, T | 1 |
| Brabec, V; Gibson, D; Kasparkova, J; Marini, V; Najajreh, Y; Novakova, O; Perez, JM | 1 |
| Angelov, D; Bednar, J; Bouvet, P; Cadet, J; Dimitrov, S; Hans, F; Lenouvel, F; Moudrianakis, EN; Müller, CW | 1 |
| Douglas, P; Kurz, EU; Lees-Miller, SP | 1 |
| Li, QH; Shao, L; Tan, Z; Wang, J | 1 |
| Bryant, KF; Coen, DM; Cox, JC; Ellington, AD; Hogle, JM; Wang, H | 1 |
| Seio, K; Sekine, M; Utagawa, E | 1 |
| Comelli, RN; Gonzalez, DH; Tron, AE | 1 |
| Lilley, DM; Liu, J | 1 |
| Chowdhury, G; Daniels, JS; Gates, KS; Greenberg, MM; Junnotula, V | 1 |
| Lippard, SJ; Ober, M | 1 |
| Silverman, SK | 1 |
| Böhm, G; Cortés, J; Galloway, IS; Hanefeld, U; Kellenberger, L; Leadlay, PF; Sauter, G; Staunton, J | 1 |
| Adelstein, SJ; Kassis, AI; Singh, A; Yang, Y | 1 |
| Chowdhury, G; Guengerich, FP | 1 |
| Albaek, N; Hansen, MH; Kumar, S; Nielsen, P; Petersen, M; Steffansen, SI | 1 |
| Fischer, B; Gottlieb, HE; Segal, M; Yavin, E; Zobel, E | 1 |
| Gilant, E; Nowicka, AM; Stojek, Z; Zabost, E | 1 |
| Lee, JE; Luo, D; Park, JH; Roh, YH; Ye, JJ | 1 |
| Korshun, VA; Kvach, MV; Prokhorenko, IA; Shmanai, VV; Stepanova, IA; Tsybulsky, DA | 1 |
| Bobrowski, K; Rak, J; Skotnicki, K; Westphal, K | 1 |
| Grewal, CS; Kent, OA; MacMillan, AM | 1 |
1 review(s) available for hydroxyl radical and oligonucleotides
| Article | Year |
|---|---|
Catalytic DNA (deoxyribozymes) for synthetic applications-current abilities and future prospects.
Topics: Base Sequence; DNA, Catalytic; Hydroxyl Radical; Oligonucleotides; RNA | 2008 |
33 other study(ies) available for hydroxyl radical and oligonucleotides
| Article | Year |
|---|---|
DNA interstrand cross-linking, DNA sequence specificity, and induced conformational changes produced by a dimeric analog of (+)-CC-1065.
Topics: Adenine; Antibiotics, Antineoplastic; Base Sequence; Copper; Cross-Linking Reagents; DNA; DNA Damage; DNA Fingerprinting; Duocarmycins; Electrophoresis; Hydroxides; Hydroxyl Radical; Indoles; Leucomycins; Molecular Sequence Data; Nucleic Acid Conformation; Oligonucleotides; Phenanthrolines; Structure-Activity Relationship; Urea | 1991 |
Hydroxyl radical generation by oligonucleotide derivatives of anthracycline antibiotic and synthetic quinone.
Topics: Base Sequence; Cyclic N-Oxides; Daunorubicin; Electron Spin Resonance Spectroscopy; Hydroxides; Hydroxyl Radical; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; NADPH-Ferrihemoprotein Reductase; Naphthoquinones; Oligonucleotides; Spin Labels | 1991 |
Recognition of 2'-hydroxyl groups by Escherichia coli ribonuclease HI.
Topics: Base Sequence; Deoxyuridine; Escherichia coli; Floxuridine; Hydrogen Bonding; Hydroxyl Radical; Kinetics; Models, Molecular; Molecular Sequence Data; Oligonucleotides; Protein Structure, Tertiary; Ribonuclease H; Ribonucleosides | 1995 |
Quantitating tertiary binding energies of 2' OH groups on the P1 duplex of the Tetrahymena ribozyme: intrinsic binding energy in an RNA enzyme.
Topics: Animals; Binding, Competitive; Catalysis; Energy Transfer; Hydroxyl Radical; Models, Chemical; Nucleic Acid Conformation; Oligonucleotides; Ribonuclease T1; RNA, Catalytic; Substrate Specificity; Tetrahymena | 1997 |
How stereochemistry affects mutagenesis by N2-deoxyguanosine adducts of 7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene: configuration of the adduct bond is more important than those of the hydroxyl groups.
Topics: Base Sequence; Benzopyrenes; DNA Adducts; Hydroxyl Radical; Molecular Conformation; Mutagenesis; Oligonucleotides; Plasmids; Stereoisomerism | 1997 |
Directed hydroxyl radical probing using iron(II) tethered to RNA.
Topics: Edetic Acid; Escherichia coli; Ferrous Compounds; Genetic Techniques; Hydroxyl Radical; Iron; Iron Chelating Agents; Nucleic Acid Heteroduplexes; Oligonucleotides; Organometallic Compounds; RNA; RNA, Ribosomal; RNA, Ribosomal, 23S; RNA, Transfer, Phe; Transcription, Genetic | 2000 |
On the efficiency of hole and electron transfer from the hydration layer to DNA: An EPR study of crystalline DNA X-irradiated at 4 K.
Topics: Cold Temperature; Crystallography, X-Ray; DNA; Electron Spin Resonance Spectroscopy; Electron Transport; Hydroxyl Radical; Models, Molecular; Oligonucleotides; Water | 2000 |
DNA, RNA and hybrid RNA-DNA oligomers of identical sequence: structural and dynamic differences.
Topics: Algorithms; Circular Dichroism; DNA; DNA Footprinting; Electrophoresis, Polyacrylamide Gel; Hydroxyl Radical; Nucleic Acid Conformation; Oligonucleotides; RNA; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thermodynamics | 2000 |
A refined prediction method for gel retardation of DNA oligonucleotides from dinucleotide step parameters: reconciliation of DNA bending models with crystal structure data.
Topics: Base Sequence; Crystallography, X-Ray; Deoxyribonuclease BamHI; DNA; DNA, Kinetoplast; Electrophoresis; Hydroxyl Radical; Models, Molecular; Molecular Sequence Data; Oligonucleotides; Predictive Value of Tests; Repetitive Sequences, Nucleic Acid; Software | 2001 |
Reproducible and inexpensive probe preparation for oligonucleotide arrays.
Topics: Ascorbic Acid; Biotinylation; Cost Savings; DNA Probes; DNA, Complementary; Edetic Acid; Ferrous Compounds; Ficusin; Flow Cytometry; Furocoumarins; Gene Deletion; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; Hydrogen Peroxide; Hydroxyl Radical; Microspheres; Neoplasms; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Oligonucleotides; Photochemistry; Polymerase Chain Reaction; Reproducibility of Results; Tumor Cells, Cultured; Ultraviolet Rays | 2001 |
Synthesis of stable-isotope enriched 5-methylpyrimidines and their use as probes of base reactivity in DNA.
Topics: Base Sequence; Carbon Isotopes; Deuterium; DNA; DNA Probes; Gas Chromatography-Mass Spectrometry; Hydroxyl Radical; Nitrogen Isotopes; Oligonucleotides; Pyrimidines; Reactive Oxygen Species; Thymidine; Thymine | 2002 |
Solution structure of a cis-opened (10R)-N6-deoxyadenosine adduct of (9S,10R)-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene in a DNA duplex.
Topics: Base Pairing; Benzopyrenes; Computer Simulation; Crystallography, X-Ray; Deoxyadenosines; DNA Adducts; Hydrocarbons; Hydroxyl Radical; Intercalating Agents; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Oligonucleotides; Protons; Software; Solutions | 2003 |
Novel base-labile protecting groups for 5'-hydroxyl protection in the synthesis of oligonucleotides.
Topics: Hydroxyl Radical; Oligonucleotides | 2002 |
Activation of trans geometry in bifunctional mononuclear platinum complexes by a piperidine ligand. Mechanistic studies on antitumor action.
Topics: Animals; Antineoplastic Agents; Base Sequence; CHO Cells; Cisplatin; Cricetinae; Cross-Linking Reagents; DNA; DNA Adducts; DNA Polymerase I; Dose-Response Relationship, Drug; HeLa Cells; HIV Reverse Transcriptase; Humans; Hydroxyl Radical; Ligands; Models, Chemical; Models, Theoretical; Molecular Sequence Data; Oligonucleotides; Piperidines; Platinum; Time Factors | 2003 |
The histone octamer is invisible when NF-kappaB binds to the nucleosome.
Topics: Animals; Binding Sites; Cryoelectron Microscopy; Deoxyribonuclease I; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Histones; Hydroxyl Radical; Lasers; NF-kappa B; NF-kappa B p50 Subunit; Nucleosomes; Oligonucleotides; Plasmids; Protein Binding; Time Factors; Transcription, Genetic; Ultraviolet Rays; Xenopus; Xenopus laevis | 2004 |
Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species.
Topics: Acetylcysteine; Androstadienes; Antibiotics, Antineoplastic; Antineoplastic Agents; Ascorbic Acid; Ataxia Telangiectasia Mutated Proteins; Binding Sites; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Cell Nucleus; DNA; DNA Damage; DNA-Binding Proteins; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Inhibitors; Histones; Humans; Hydroxyl Radical; Image Processing, Computer-Assisted; Immunoblotting; Immunoprecipitation; Microscopy, Fluorescence; Oligonucleotides; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Radiation, Ionizing; Reactive Oxygen Species; Serine; Signal Transduction; Threonine; Time Factors; Transcription, Genetic; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Wortmannin | 2004 |
Fragmentation and rapid shortening of telomere in HeLa cells in the early phase of hydroxyl radical-induced apoptosis.
Topics: Apoptosis; Cell Cycle; DNA; DNA Damage; DNA Fragmentation; HeLa Cells; Humans; Hydroxyl Radical; Oligonucleotides; Telomere; Transfection | 2005 |
Binding of herpes simplex virus-1 US11 to specific RNA sequences.
Topics: Base Sequence; Binding Sites; Consensus Sequence; Electrophoretic Mobility Shift Assay; Herpesvirus 1, Human; Hydroxyl Radical; Molecular Sequence Data; Oligonucleotides; Protein Structure, Tertiary; Ribonucleases; RNA; RNA-Binding Proteins; RNA, Double-Stranded; Viral Proteins | 2005 |
A new protecting group for the 5'-hydroxyl group having O-S single bond oxidatively cleavable under mild conditions.
Topics: Catalysis; Furans; Hydroxides; Hydroxyl Radical; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Biology; Oligonucleotides; Oxygen; Sulfur; Thymidine | 2005 |
Structure of homeodomain-leucine zipper/DNA complexes studied using hydroxyl radical cleavage of DNA and methylation interference.
Topics: Base Sequence; Binding Sites; DNA; DNA Footprinting; DNA Methylation; Electrophoretic Mobility Shift Assay; Helianthus; Homeodomain Proteins; Hydroxyl Radical; Leucine Zippers; Models, Molecular; Molecular Structure; Oligonucleotides; Plant Proteins; Protein Binding; Recombinant Proteins | 2005 |
The role of specific 2'-hydroxyl groups in the stabilization of the folded conformation of kink-turn RNA.
Topics: Archaeoglobus fulgidus; Crystallography, X-Ray; Deoxyribose; Electrophoresis, Polyacrylamide Gel; Fluorescence Resonance Energy Transfer; Haloarcula marismortui; Humans; Hydrogen Bonding; Hydroxyl Radical; Metals; Models, Molecular; Nucleic Acid Conformation; Oligonucleotides; RNA; RNA, Archaeal; RNA, Small Nuclear; Thermodynamics; Thermus thermophilus | 2007 |
DNA strand damage product analysis provides evidence that the tumor cell-specific cytotoxin tirapazamine produces hydroxyl radical and acts as a surrogate for O(2).
Topics: Antineoplastic Agents; Chromatography, High Pressure Liquid; Cytotoxins; DNA Damage; Furaldehyde; Hydrogen; Hydroxyl Radical; Malondialdehyde; Models, Chemical; Neoplasms; Oligonucleotides; Sugar Acids; Time Factors; Tirapazamine; Transcription, Genetic; Triazines | 2007 |
A 1,2-d(GpG) cisplatin intrastrand cross-link influences the rotational and translational setting of DNA in nucleosomes.
Topics: Cisplatin; Cross-Linking Reagents; Dinucleoside Phosphates; DNA; DNA Damage; Guanosine Monophosphate; Hydroxyl Radical; Nucleic Acid Conformation; Nucleosomes; Oligonucleotides; Rotation | 2008 |
A polylinker approach to reductive loop swaps in modular polyketide synthases.
Topics: Amino Acid Sequence; Biocatalysis; DNA; Hydroxyl Radical; Lactones; Molecular Sequence Data; Oligonucleotides; Oxidation-Reduction; Peptides; Polyketide Synthases; Protein Engineering; Protein Structure, Tertiary; Saccharopolyspora; Stereoisomerism; Substrate Specificity | 2008 |
Synthesis and application of molecular probe for detection of hydroxyl radicals produced by Na(125)I and gamma-rays in aqueous solution.
Topics: Coumarins; Fluorescent Dyes; Gamma Rays; Hydrogen-Ion Concentration; Hydroxyl Radical; Iodine Radioisotopes; Molecular Probes; Nucleic Acid Conformation; Oligonucleotides; Sodium Iodide; Solutions; Spermidine; Spermine; Water | 2008 |
Tandem mass spectrometry-based detection of c4'-oxidized abasic sites at specific positions in DNA fragments.
Topics: Antineoplastic Agents; Base Sequence; Bleomycin; Chromatography, High Pressure Liquid; DNA; DNA Damage; Hydroxyl Radical; Ions; Oligonucleotides; Oxidation-Reduction; Radiation, Ionizing; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2009 |
Synthesis of functionalized carbocyclic locked nucleic acid analogues by ring-closing diene and enyne metathesis and their influence on nucleic acid stability and structure.
Topics: Carbon; Chemistry, Organic; Circular Dichroism; DNA; Hydroxyl Radical; Kinetics; Models, Chemical; Molecular Conformation; Nucleic Acid Hybridization; Nucleic Acids; Oligonucleotides; RNA; Temperature; Thermodynamics | 2009 |
Oligonucleotides are potent antioxidants acting primarily through metal ion chelation.
Topics: Antioxidants; Base Composition; Chelating Agents; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Hydrogen Peroxide; Hydroxyl Radical; Magnetic Resonance Spectroscopy; Metals; Nitrogen; Oligonucleotides; Oxidation-Reduction | 2010 |
Influence of percentage of guanine molecules, OH radicals, UV irradiation and temperature on electrooxidation of short synthetic oligonucleotides.
Topics: Circular Dichroism; Electrochemical Techniques; Guanine; Hydroxyl Radical; Oligonucleotides; Oxidation-Reduction; Spectrophotometry, Ultraviolet; Temperature; Ultraviolet Rays | 2011 |
Systematic studies of UV stability and photopolymerization efficiency of DNA-based nanomaterials.
Topics: DNA; DNA Fragmentation; Hydroxyl Radical; Nanostructures; Nucleic Acid Conformation; Oligonucleotides; Photochemical Processes; Propane; Singlet Oxygen; Ultraviolet Rays | 2012 |
Non-nucleoside phosphoramidites of xanthene dyes (FAM, JOE, and TAMRA) for oligonucleotide labeling.
Topics: Aminophenols; Fluoresceins; Fluorescent Dyes; Hydroxyl Radical; Indicators and Reagents; Isomerism; Oligonucleotides; Organophosphorus Compounds; Rhodamines; Xanthenes | 2013 |
Radiation damage to single stranded oligonucleotide trimers labelled with 5-iodopyrimidines.
Topics: Chromatography, High Pressure Liquid; DNA, Single-Stranded; Electrons; Hydroxyl Radical; Idoxuridine; Iodine; Mass Spectrometry; Oligonucleotides; Pyrimidines; Radiation, Ionizing | 2016 |
Radical probing of spliceosome assembly.
Topics: Crystallography, X-Ray; DNA-Directed RNA Polymerases; Hydroxyl Radical; Molecular Probe Techniques; Molecular Probes; Oligonucleotides; RNA Precursors; RNA Splicing; Spliceosomes; Viral Proteins | 2017 |