Page last updated: 2024-09-04

hydroxyl radical and ng-nitroarginine methyl ester

hydroxyl radical has been researched along with ng-nitroarginine methyl ester in 29 studies

Compound Research Comparison

Studies
(hydroxyl radical)
Trials
(hydroxyl radical)
Recent Studies (post-2010)
(hydroxyl radical)
Studies
(ng-nitroarginine methyl ester)
Trials
(ng-nitroarginine methyl ester)
Recent Studies (post-2010) (ng-nitroarginine methyl ester)
10,147263,65712,6401172,342

Protein Interaction Comparison

ProteinTaxonomyhydroxyl radical (IC50)ng-nitroarginine methyl ester (IC50)
Neutrophil elastaseHomo sapiens (human)2.7
Nitric oxide synthase, endothelialHomo sapiens (human)2.1
Nitric oxide synthase, brainHomo sapiens (human)1.1167
Nitric oxide synthase, inducibleMus musculus (house mouse)2.6
Nitric oxide synthase, inducibleHomo sapiens (human)8
Collagenase 3Homo sapiens (human)2.7

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (37.93)18.2507
2000's15 (51.72)29.6817
2010's3 (10.34)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
DeCampli, WM; Obayashi, DY; Wanna, FS; Young, JN1
Boulu, RG; Callebert, J; Lancelot, E; Lerouet, D; Plotkine, M; Revaud, ML1
Langenstroer, P; Pieper, GM; Siebeneich, W1
Huang, NC; Quast, MJ; Wei, J1
Boulu, RG; Callebert, J; Lancelot, E; Lecanu, L; Plotkine, M; Revaud, ML1
Quast, MJ; Wei, J1
Baron, C; Beauchamp, M; Filep, JG; Paquette, Y1
Boulu, RG; Callebert, J; Lancelot, E; Plotkine, M; Revaud, ML1
Aeed, H; Avni, Y; Bruck, R; Halpern, Z; Matas, Z; Shirin, H; Zaidel, L1
Hindmarsh, JG; Jenner, P; Rose, S1
Altura, BM; Altura, BT; Yang, Z; Zhang, A1
Bennett, PB; Boso, AE; Demchenko, IT; Piantadosi, CA; Whorton, AR1
Ebihara, A; Obata, T; Yamanaka, Y1
Ambrosio, G; Berlowitz, CO; Bettini, M; Biondi, R; Kass, DA; L'Abbate, A; Lee, CI; Paolocci, N; Rossi, R; Xia, Y; Zweier, JL1
Ikeya, K; Kashimoto, S; Kumazawa, T; Kume, M1
Obata, T; Yamanaka, Y2
Dikshit, M; Raghavan, SA; Rajanikanth, M; Srivastava, P1
Arai, M; Chen, X; Fujiwara, H; Lu, C; Minatoguchi, S; Misao, Y; Takemura, G; Uno, Y; Wang, N1
Andriantsitohaina, R; Pechánová, O; Zenebe, W1
Ebinger, G; Hachimi-Idrissi, S; Michotte, Y; Sarre, S; Van Hemelrijck, A1
Obata, T1
Barton, M; Bhattacharya, I; Haas, E; Hofmann-Lehmann, R; Kretz, M; Minotti, R; Mundy, AL; Widmer, CC1
Endo, T; Hara, S; Kuriiwa, F; Kurosaki, K; Mizukami, H; Mukai, T1
Ito, S; Matsubayashi, K; Mori, T; Sawaguchi, T1
Chen, SC; Chen, WC1
Araújo, RM; Castro, AJ; Leite, EL; Nascimento, MS; Paiva, AA; Rocha, FA; Santos, ND; Will, LS; Xavier, CA1
Chen, S; Fan, S; Ikejima, T; Li, L; Onodera, S; Qi, M; Tashiro, S; Yu, Y1
Black, SM; Harris, VA; Kumar, S; Lu, Q; Rafikov, R; Sun, X1

Reviews

1 review(s) available for hydroxyl radical and ng-nitroarginine methyl ester

ArticleYear
Nitric oxide and MPP+-induced hydroxyl radical generation.
    Journal of neural transmission (Vienna, Austria : 1996), 2006, Volume: 113, Issue:9

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Brain Chemistry; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Enzyme Inhibitors; Estrogens, Conjugated (USP); Humans; Hydroxyl Radical; Microdialysis; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Oxidants; Potassium

2006

Other Studies

28 other study(ies) available for hydroxyl radical and ng-nitroarginine methyl ester

ArticleYear
Simultaneous manipulation of the nitric oxide and prostanoid pathways reduces myocardial reperfusion injury.
    The Journal of thoracic and cardiovascular surgery, 1995, Volume: 110, Issue:4 Pt 1

    Topics: Animals; Arginine; Aspirin; Cardioplegic Solutions; Coronary Circulation; Cyclic GMP; Glucose; Heart; Heart Rate; Hydroxyl Radical; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Rats; Rats, Sprague-Dawley; Tromethamine; Vascular Resistance

1995
Role of the L-arginine-nitric oxide pathway in the basal hydroxyl radical production in the striatum of awake rats as measured by brain microdialysis.
    Neuroscience letters, 1995, Dec-29, Volume: 202, Issue:1-2

    Topics: Animals; Antioxidants; Arginine; Chromatography, High Pressure Liquid; Consciousness; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Neostriatum; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley

1995
Diabetic-induced endothelial dysfunction in rat aorta: role of hydroxyl radicals.
    Cardiovascular research, 1997, Volume: 34, Issue:1

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Catalase; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Diuretics, Osmotic; Dose-Response Relationship, Drug; Endothelium, Vascular; Hydroxyl Radical; In Vitro Techniques; Indomethacin; Male; Mannitol; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; Nitroglycerin; Norepinephrine; Phenylacetates; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane; Sulfonamides; Superoxide Dismutase; Vasoconstrictor Agents; Vasodilator Agents

1997
Hydroxyl radical formation in hyperglycemic rats during middle cerebral artery occlusion/reperfusion.
    Free radical biology & medicine, 1997, Volume: 23, Issue:7

    Topics: Animals; Arterial Occlusive Diseases; Cerebral Arteries; Cerebral Infarction; Enzyme Inhibitors; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hyperglycemia; In Vitro Techniques; Magnetic Resonance Imaging; Male; Microdialysis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Reperfusion Injury

1997
Glutamate induces hydroxyl radical formation in vivo via activation of nitric oxide synthase in Sprague-Dawley rats.
    Neuroscience letters, 1998, Feb-20, Volume: 242, Issue:3

    Topics: Animals; Corpus Striatum; Enzyme Inhibitors; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid

1998
Effect of nitric oxide synthase inhibitor on a hyperglycemic rat model of reversible focal ischemia: detection of excitatory amino acids release and hydroxyl radical formation.
    Brain research, 1998, Apr-27, Volume: 791, Issue:1-2

    Topics: Animals; Cell Survival; Citrulline; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Inhibitors; Glutamic Acid; Hydroxyl Radical; Hyperglycemia; Ischemic Attack, Transient; Magnetic Resonance Imaging; Male; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley

1998
Peroxynitrite mediates IL-8 gene expression and production in lipopolysaccharide-stimulated human whole blood.
    Journal of immunology (Baltimore, Md. : 1950), 1998, Nov-15, Volume: 161, Issue:10

    Topics: Adult; Female; Gene Expression Regulation; Guanidines; Humans; Hydroxyl Radical; Interleukin-8; Lipopolysaccharides; Male; Middle Aged; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Pyrrolidines; RNA, Messenger; Thiocarbamates

1998
A microdialysis study investigating the mechanisms of hydroxyl radical formation in rat striatum exposed to glutamate.
    Brain research, 1998, Nov-02, Volume: 809, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Animals; Corpus Striatum; Cyclic N-Oxides; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Iron Chelating Agents; Microdialysis; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitrogen Oxides; Quinacrine; Rats; Rats, Sprague-Dawley

1998
The hydroxyl radical scavengers dimethylsulfoxide and dimethylthiourea protect rats against thioacetamide-induced fulminant hepatic failure.
    Journal of hepatology, 1999, Volume: 31, Issue:1

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Dimethyl Sulfoxide; Free Radical Scavengers; Hepatic Encephalopathy; Hydroxyl Radical; L-Lactate Dehydrogenase; Liver; Male; NG-Nitroarginine Methyl Ester; Pentoxifylline; Rats; Rats, Wistar; Thioacetamide; Thiourea

1999
Neuronal nitric oxide synthase inhibition reduces MPP+-evoked hydroxyl radical formation but not dopamine efflux in rat striatum.
    Journal of neural transmission (Vienna, Austria : 1996), 1999, Volume: 106, Issue:5-6

    Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroxybenzoates; Hydroxyl Radical; In Vitro Techniques; Indazoles; Male; Microdialysis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Wistar

1999
Hydrogen peroxide-induced endothelium-dependent relaxation of rat aorta involvement of Ca2+ and other cellular metabolites.
    General pharmacology, 1999, Volume: 33, Issue:4

    Topics: Animals; Aorta, Thoracic; Calcium; Chelating Agents; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Egtazic Acid; Endothelium, Vascular; Enzyme Inhibitors; Fatty Acids, Unsaturated; Hydrogen Peroxide; Hydroxyl Radical; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; omega-N-Methylarginine; Proadifen; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents

1999
Hyperbaric oxygen reduces cerebral blood flow by inactivating nitric oxide.
    Nitric oxide : biology and chemistry, 2000, Volume: 4, Issue:6

    Topics: Animals; Blood Flow Velocity; Blood Gas Analysis; Blood Pressure; Cerebrovascular Circulation; Corpus Striatum; Electroencephalography; Enzyme Inhibitors; Hydrazines; Hydroxybenzoates; Hydroxyl Radical; Hyperbaric Oxygenation; Injections, Intravenous; Microdialysis; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Sprague-Dawley; Superoxide Dismutase

2000
Effect of fluvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on nitric oxide-induced hydroxyl radical generation in the rat heart.
    Biochimica et biophysica acta, 2001, Apr-30, Volume: 1536, Issue:1

    Topics: Animals; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Fluvastatin; Heart; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Male; Microdialysis; Models, Chemical; Myocardial Ischemia; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Potassium Chloride; Rats; Rats, Wistar

2001
Oxygen radical-mediated reduction in basal and agonist-evoked NO release in isolated rat heart.
    Journal of molecular and cellular cardiology, 2001, Volume: 33, Issue:4

    Topics: Acetylcholine; Animals; Bradykinin; Cyclooxygenase Inhibitors; Electrolysis; Heart; Hydroxyl Radical; In Vitro Techniques; Indomethacin; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Superoxides

2001
[The influence of N-nitro-L-arginine methyl ester (L-NAME) on hydroxyl free radical formation in the post-ischemic reperfused heart of anesthetized rats].
    Masui. The Japanese journal of anesthesiology, 2001, Volume: 50, Issue:4

    Topics: Anesthetics, Inhalation; Animals; Drug Interactions; Enzyme Inhibitors; Hemodynamics; Hydroxyl Radical; In Vitro Techniques; Male; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar

2001
Nitric oxide enhances MPP(+)-induced hydroxyl radical generation via depolarization activated nitric oxide synthase in rat striatum.
    Brain research, 2001, Jun-01, Volume: 902, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; Allopurinol; Animals; Dopamine; Enzyme Inhibitors; Extracellular Space; Herbicides; Hydroxybenzoates; Hydroxyl Radical; Iron; Iron Chelating Agents; Male; Membrane Potentials; Microdialysis; Neostriatum; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Parkinson Disease; Potassium; Rats; Rats, Wistar

2001
Nitric oxide induces hydroxyl radical generation in rat hearts via depolarization-induced nitric oxide synthase activation.
    Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 364, Issue:1

    Topics: Allopurinol; Animals; Dose-Response Relationship, Drug; Enzyme Activation; Female; Heart; Hydroxyl Radical; Male; Microdialysis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Potassium; Potassium Chloride; Rats; Rats, Wistar; Tyramine

2001
Role of endogenous reactive oxygen derived species and cyclooxygenase mediators in 5-hydroxytryptamine-induced contractions in rat aorta: relationship to nitric oxide.
    Pharmacological research, 2002, Volume: 45, Issue:5

    Topics: Amitrole; Animals; Aorta; Catalase; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Serotonin; Superoxide Dismutase

2002
Quinaprilat reduces myocardial infarct size involving nitric oxide production and mitochondrial KATP channel in rabbits.
    Journal of cardiovascular pharmacology, 2003, Volume: 41, Issue:6

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Decanoic Acids; Heart Ventricles; Hemodynamics; Hydroxy Acids; Hydroxyl Radical; Male; Membrane Proteins; Mitochondria, Heart; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Potassium Channel Blockers; Potassium Channels; Rabbits; Tetrahydroisoquinolines

2003
Red wine polyphenols induce vasorelaxation by increased nitric oxide bioactivity.
    Physiological research, 2003, Volume: 52, Issue:4

    Topics: Acetylcholine; Animals; Arginine; Calcium Channel Blockers; Dose-Response Relationship, Drug; Femoral Artery; Flavonoids; Half-Life; Hydroxyl Radical; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; Oxidants; Phenols; Polyphenols; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents; Verapamil; Wine

2003
Post-ischaemic mild hypothermia inhibits apoptosis in the penumbral region by reducing neuronal nitric oxide synthase activity and thereby preventing endothelin-1-induced hydroxyl radical formation.
    The European journal of neuroscience, 2005, Volume: 22, Issue:6

    Topics: Amino Acids; Animals; Apoptosis; Body Temperature; Brain Ischemia; Caspase 3; Caspases; Cerebral Cortex; Cerebral Infarction; Endothelin-1; Enzyme Inhibitors; Extracellular Space; Hydroxyl Radical; Hypothermia; Immunohistochemistry; Male; Microdialysis; Neostriatum; NG-Nitroarginine Methyl Ester; Oxidants; Rats; Rats, Wistar

2005
Fat intake modifies vascular responsiveness and receptor expression of vasoconstrictors: implications for diet-induced obesity.
    Cardiovascular research, 2007, Jan-15, Volume: 73, Issue:2

    Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Blotting, Western; Cholesterol; Dietary Fats; Endothelin-1; Endothelium, Vascular; Gene Expression; Glucose Tolerance Test; Hydroxyl Radical; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Obesity; Receptors, Angiotensin; Receptors, Endothelin; Reverse Transcriptase Polymerase Chain Reaction; Vasoconstrictor Agents; Vasodilator Agents

2007
Role of nitric oxide system in hydroxyl radical generation in rat striatum due to carbon monoxide poisoning, as determined by microdialysis.
    Toxicology, 2007, Sep-24, Volume: 239, Issue:1-2

    Topics: Administration, Inhalation; Animals; Antimetabolites; Arginine; Carbon Monoxide; Carbon Monoxide Poisoning; Drug Interactions; Enzyme Inhibitors; Hydroxyl Radical; Inhalation Exposure; Male; Microdialysis; Neostriatum; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley

2007
Comparison of nitric oxide synthase inhibitors, phospholipase A2 inhibitor and free radical scavengers as attenuators of opioid withdrawal syndrome.
    Behavioural pharmacology, 2007, Volume: 18, Issue:8

    Topics: alpha-Tocopherol; Animals; Ascorbic Acid; Enzyme Inhibitors; Free Radical Scavengers; Hydroxyl Radical; Male; Mice; Naloxone; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Opioid-Related Disorders; Phospholipase A2 Inhibitors; Substance Withdrawal Syndrome; Superoxides

2007
Vascular leakage induced by exposure to arsenic via increased production of NO, hydroxyl radical and peroxynitrite.
    Microvascular research, 2008, Volume: 75, Issue:3

    Topics: Animals; Arsenites; Blood Vessels; Capillary Permeability; Carbon; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Inhibitors; Evans Blue; Free Radical Scavengers; Guanidines; Hydroxyl Radical; Injections, Intradermal; Injections, Intravenous; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Skin; Sodium Compounds; Thiourea; Tyrosine

2008
Antioxidant and anti-inflammatory effect of polysaccharides from Lobophora variegata on zymosan-induced arthritis in rats.
    International immunopharmacology, 2011, Volume: 11, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arthritis; Diclofenac; Edema; Hydroxyl Radical; Immunohistochemistry; Leukocytes; Magnetic Resonance Spectroscopy; Molybdenum; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Phaeophyceae; Phosphoric Acids; Polysaccharides; Rats; Rats, Wistar; Spectrophotometry, Infrared; Superoxides; Tumor Necrosis Factor-alpha; Zymosan

2011
Silibinin induced-autophagic and apoptotic death is associated with an increase in reactive oxygen and nitrogen species in HeLa cells.
    Free radical research, 2011, Volume: 45, Issue:11-12

    Topics: Acetylcysteine; Adenine; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Caspase 3; Cell Survival; Glutathione; HeLa Cells; Humans; Hydroxyl Radical; Membrane Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Reactive Nitrogen Species; Reactive Oxygen Species; Silybin; Silymarin

2011
Nitric oxide induces hypoxia ischemic injury in the neonatal brain via the disruption of neuronal iron metabolism.
    Redox biology, 2015, Volume: 6

    Topics: Aconitate Hydratase; Animals; Animals, Newborn; Cell Death; Cell Hypoxia; Culture Media; Deferoxamine; Ferritins; Gene Expression Regulation; Glucose; Hippocampus; Hydroxyl Radical; Hypoxia-Ischemia, Brain; Iron; Microtomy; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptors, Transferrin; Tissue Culture Techniques

2015