hydroxyl radical has been researched along with n-methylaspartate in 11 studies
| Studies (hydroxyl radical) | Trials (hydroxyl radical) | Recent Studies (post-2010) (hydroxyl radical) | Studies (n-methylaspartate) | Trials (n-methylaspartate) | Recent Studies (post-2010) (n-methylaspartate) |
|---|---|---|---|---|---|
| 10,147 | 26 | 3,657 | 10,408 | 59 | 1,902 |
| Protein | Taxonomy | hydroxyl radical (IC50) | n-methylaspartate (IC50) |
|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 5.175 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 5.175 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 5.175 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 5.175 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 5.175 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 5.175 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 5.175 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 7 (63.64) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bennett, JP; Hammer, B; Parker, WD | 1 |
| Beal, MF; Cipolloni, PB; Ferrante, RJ; Henshaw, DR; Jenkins, BG; Kowall, NW; Rosen, BR; Schulz, JB; Siwek, D | 1 |
| Acworth, IN; Maher, TJ; McCabe, DR | 1 |
| Ayata, C; Ayata, G; Beal, MF; Christie, RH; Endres, M; Ferrante, RJ; Hara, H; Huang, PL; Hyman, BT; Kim, A; Matthews, RT; Moskowitz, MA; Waeber, C | 1 |
| Barbanel, G; Kamenka, JM; Laplanche, L | 1 |
| Barbanel, G; Cambonie, G; Kamenka, JM; Laplanche, L | 1 |
| Barbanel, G; Cambonie, G; Kamenka, JM | 1 |
| Hayashi, Y; Kamada, H; Mitsuyama, Y; Nakajima, A; Ohya-Nishiguchi, H; Ueda, Y; Yokoyama, H | 1 |
| Albrecht, J; Anderzhanova, E; Hilgier, W; Oja, SS; Saransaari, P | 1 |
| Anderzhanova, E; Oja, SS; Saransaari, P | 1 |
| Hara, H; Inokuchi, Y; Ishibashi, T; Nakajima, Y; Otsubo, K; Shimazawa, M | 1 |
11 other study(ies) available for hydroxyl radical and n-methylaspartate
| Article | Year |
|---|---|
NMDA receptors increase OH radicals in vivo by using nitric oxide synthase and protein kinase C.
Topics: Alkaloids; Amino Acid Oxidoreductases; Analysis of Variance; Animals; Corpus Striatum; Dizocilpine Maleate; Hydroxyl Radical; Male; N-Methylaspartate; Neurons; Nitric Oxide Synthase; Protein Kinase C; Rats; Receptors, N-Methyl-D-Aspartate; Staurosporine | 1993 |
Involvement of free radicals in excitotoxicity in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Cell Death; Cells, Cultured; Cyclic N-Oxides; Dizocilpine Maleate; Electrophysiology; Free Radical Scavengers; Free Radicals; Hydroxyl Radical; Kainic Acid; Male; N-Methylaspartate; Neurons; Nitrogen Oxides; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 1995 |
Improved method for the estimation of hydroxyl free radical levels in vivo based on liquid chromatography with electrochemical detection.
Topics: Animals; Benzoates; Cerebral Cortex; Chromatography, High Pressure Liquid; Corpus Striatum; Dizocilpine Maleate; Drug Stability; Excitatory Amino Acid Antagonists; Free Radicals; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Kidney; Liver; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Salicylates; Sensitivity and Specificity | 1997 |
Mechanisms of reduced striatal NMDA excitotoxicity in type I nitric oxide synthase knock-out mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Binding Sites; Corpus Striatum; Dizocilpine Maleate; DNA Fragmentation; Excitatory Amino Acid Antagonists; Hydroxyl Radical; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Nitric Oxide Synthase; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Tyrosine | 1997 |
The novel non-competitive N-methyl-D-aspartate antagonist gacyclidine blocks the glutamate-induced release of hydroxyl radicals in the striatum under conditions in which dizocilpine does not. A microdialysis study in rats.
Topics: Animals; Binding, Competitive; Corpus Striatum; Cyclohexanes; Cyclohexenes; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamates; Hydroxyl Radical; Male; Microdialysis; N-Methylaspartate; Neuroprotective Agents; Oxidative Stress; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2000 |
N-methyl-D-aspartate but not glutamate induces the release of hydroxyl radicals in the neonatal rat: modulation by group I metabotropic glutamate receptors.
Topics: Animals; Animals, Newborn; Corpus Striatum; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hydroxybenzoates; Hydroxyl Radical; Hypoxia-Ischemia, Brain; Ibotenic Acid; Indans; Microdialysis; N-Methylaspartate; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols | 2000 |
Glutamate inhibition of NMDA-induced hydroxyl radical release: an ontogenic study in rat.
Topics: Aging; Animals; Animals, Newborn; Brain; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hydroxyl Radical; Microdialysis; N-Methylaspartate; Neurons; Neurotoxins; Oxidative Stress; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Salicylates | 2001 |
Nitric oxide and hydroxyl radicals initiate lipid peroxidation by NMDA receptor activation.
Topics: Animals; Blotting, Western; Cell Line; Electron Spin Resonance Spectroscopy; Excitatory Amino Acid Agonists; Hydroxyl Radical; Lipid Peroxidation; N-Methylaspartate; Nitric Oxide; PC12 Cells; Rats; Receptors, N-Methyl-D-Aspartate | 2002 |
Taurine reduces ammonia- and N-methyl-D-aspartate-induced accumulation of cyclic GMP and hydroxyl radicals in microdialysates of the rat striatum.
Topics: Ammonium Chloride; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Cyclic GMP; Hydroxyl Radical; Male; Microdialysis; N-Methylaspartate; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Taurine | 2003 |
Neuroprotective mechanisms of taurine in vivo.
Topics: Ammonium Chloride; Amphetamines; Animals; Brain; Brain Chemistry; Central Nervous System Stimulants; Dopamine; Glutamic Acid; Glycine; Hydroxyl Radical; Male; Microdialysis; N-Methylaspartate; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Sydnones; Taurine | 2006 |
Astaxanthin, a dietary carotenoid, protects retinal cells against oxidative stress in-vitro and in mice in-vivo.
Topics: Animals; Apoptosis; Carrier Proteins; Cell Survival; Cells, Cultured; Chromans; Dose-Response Relationship, Drug; Ferric Compounds; Fluoresceins; Hydrogen Peroxide; Hydroxyl Radical; In Situ Nick-End Labeling; Lipid Peroxidation; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Oxidative Stress; Phosphate-Binding Proteins; Rats; Reactive Oxygen Species; Retina; Retinal Diseases; Retinal Ganglion Cells; Xanthophylls | 2008 |