Page last updated: 2024-09-04

hydroxyl radical and metyrapone

hydroxyl radical has been researched along with metyrapone in 2 studies

Compound Research Comparison

Studies
(hydroxyl radical)
Trials
(hydroxyl radical)
Recent Studies (post-2010)
(hydroxyl radical)
Studies
(metyrapone)
Trials
(metyrapone)
Recent Studies (post-2010) (metyrapone)
10,147263,6573,415128250

Protein Interaction Comparison

ProteinTaxonomyhydroxyl radical (IC50)metyrapone (IC50)
Cytochrome P450 1A2Homo sapiens (human)4.8
Cytochrome P450 3A4Homo sapiens (human)2.8659
Cytochrome P450 2C8Homo sapiens (human)5
Cytochrome P450 2D6Homo sapiens (human)4.6
Cytochrome P450 11B1, mitochondrial Bos taurus (cattle)7.83
Cytochrome P450 11B1, mitochondrialRattus norvegicus (Norway rat)4.7357
Cytochrome P450 11B1, mitochondrialHomo sapiens (human)0.0181
Cytochrome P450 11B2, mitochondrialHomo sapiens (human)0.0838
Cytochrome P450 2C19Homo sapiens (human)5

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cederbaum, AI; Krikun, G1
Aldern, KA; Harris, SE; Hornsby, PJ1

Other Studies

2 other study(ies) available for hydroxyl radical and metyrapone

ArticleYear
Evaluation of microsomal pathways of oxidation of alcohols and hydroxyl radical scavenging agents with carbon monoxide and cobalt protoporphyrin IX.
    Biochemical pharmacology, 1985, Aug-15, Volume: 34, Issue:16

    Topics: Alcohols; Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Deferoxamine; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Male; Metyrapone; Microsomes, Liver; Oxidation-Reduction; Porphyrins; Proadifen; Protoporphyrins; Rats; Rats, Inbred Strains; Superoxides

1985
Mode of action of sulfoxides in preventing loss of activity of 11 beta-hydroxylase in cultured bovine adrenocortical cells.
    Chemico-biological interactions, 1984, Volume: 51, Issue:3

    Topics: Adrenal Cortex; Animals; Cattle; Cells, Cultured; Dimethyl Sulfoxide; Free Radicals; Hydrocortisone; Hydroxides; Hydroxyl Radical; Metyrapone; Radiation-Protective Agents; Steroid 11-beta-Hydroxylase; Steroid Hydroxylases; Sulfoxides

1984