Page last updated: 2024-09-04

hydroxyl radical and metallothionein

hydroxyl radical has been researched along with metallothionein in 34 studies

Compound Research Comparison

Studies (hydroxyl radical)	Trials (hydroxyl radical)	Recent Studies (post-2010) (hydroxyl radical)	Studies (metallothionein)	Trials (metallothionein)	Recent Studies (post-2010) (metallothionein)
10,147	26	3,657	9,390	41	2,223

Research

Studies (34)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (5.88)	18.7374
1990's	16 (47.06)	18.2507
2000's	13 (38.24)	29.6817
2010's	3 (8.82)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chen, W; Du, XH; Yang, CL; Zou, WZ	1
Buchman, C; Dixon, W; Karin, M; Skroch, P; Tullius, TD	1
Abel, J; de Ruiter, N	1
Metodiewa, D; Płonka, A; Szymańska, J; Zelazowski, A	1
Du, XH; Yang, CL	1
Chen, W; Du, XH; Han, YX; Yang, CL; Zhao, JH	1
Felix, K; Hartmann, HJ; Lengfelder, E; Weser, U	1
Chubatsu, LS; Meneghini, R	1
Ozawa, T; Rui, M; Suzuki, KT; Ueda, J	1
Nakamura, M; Nakayama, K; Ohyama, T; Shishido, N; Yumino, K	1
Hiramoto, K; Kikugawa, K; Ojima, N	1
Meneghini, R	1
Ebadi, M; Hiramatsu, M; Kumari, MV	2
Chen, Y; Ru, B; Xiong, Y	1
Byrnes, RW; Elgohary, WG; Krezoski, SO; Petering, DH; Sidhu, S	1
Burke, WJ; Ebadi, M; el-Sayed, MA; Folks, DG; Hiramatsu, M	1
O'Brien, P; Salacinski, HJ	1
Borisenko, GG; Fabisiak, JP; Kagan, VE; Korotaeva, A; Lazo, JS; Pitt, BR; Tyurin, VA; Tyurina, YY	1
Borisenko, GG; Fabisiak, JP; Kagan, VE; Lazo, JS; Liu, SX; Pitt, BR; Tyurin, VA	1
Fujimura, H; Nagano, S; Sakoda, S; Satoh, M; Sumi, H; Tohyama, C; Yanagihara, T	1
Nakamura, M; Nakayama, K; Ohyama, T; Shishido, N; Takazawa, A	1
Choi, CY; Hahm, KS; Jeong, HG; Lee, DG; Moon, AR; Oh, DH; You, HJ	1
Nair, KM; Sreedhar, B; Subramaniyan, R	1
Akashi, K; Ishida, Y; Nishimura, N; Yokota, A	1
Baldacchino, G; Bataille, C; Coppo, M; Cosson, RP; Pin, S; Renault, JP; Trehen, C; Vigneron, G	1
Camus, L; Gomiero, A; Marangon, I; Nasci, C; Pampanin, DM; Volpato, E	1
Benedetti, M; Bocchetti, R; Fattorini, D; Gorbi, S; Machella, N; Notti, A; Piva, F; Regoli, F; Tedesco, S	1
Cai, B; Chen, D; Huang, ZX; Sun, HZ; Teng, XC; Wang, KQ; Wang, Y; Xie, Y; Zhang, MJ; Zheng, Q; Zhou, GM	1
Ayuk-Takem, LT; Badisa, RB; Badisa, VL; Ikediobi, CO; Latinwo, LM; Nwoga, J; Odewumi, CO; West, J	1
Faller, P; Meloni, G; Vasák, M	1
Wu, R; Zhang, Q; Zhang, Z; Zhu, J	1
Banerjee, S; Baxi, D; Joshi, N; Mukherjee, R; Ramachandran, AV; Singh, PK	1
Feng, S; Han, S; Huang, P; Li, J; Meng, P; Shi, L; Sun, H; Sun, Z; Wang, J; Wang, M	1

Reviews

1 review(s) available for hydroxyl radical and metallothionein

Article	Year
Iron homeostasis, oxidative stress, and DNA damage. Free radical biology & medicine, 1997, Volume: 23, Issue:5 Topics: Animals; Calcium; Cell Nucleus; DNA Damage; Homeostasis; Humans; Hydroxyl Radical; Iron; Metallothionein; Oxidative Stress	1997

Other Studies

33 other study(ies) available for hydroxyl radical and metallothionein

Article	Year
Protective effect of zinc-induced metallothionein synthesis on gentamicin nephrotoxicity in rats. Renal failure, 1991, Volume: 13, Issue:4 Topics: Acute Kidney Injury; Animals; Free Radical Scavengers; Gentamicins; Hydroxides; Hydroxyl Radical; Kidney Cortex; Kidney Tubular Necrosis, Acute; Male; Malondialdehyde; Metallothionein; Rats; Rats, Inbred Strains; Sulfates; Superoxide Dismutase; Zinc; Zinc Sulfate	1991
A single amino acid change in CUP2 alters its mode of DNA binding. Molecular and cellular biology, 1990, Volume: 10, Issue:9 Topics: Base Composition; Base Sequence; Cloning, Molecular; Copper; Deoxyribonuclease I; DNA-Binding Proteins; DNA, Fungal; Free Radicals; Fungal Proteins; Gene Expression Regulation, Fungal; Genes, Fungal; Hydroxides; Hydroxyl Radical; Metallothionein; Models, Molecular; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Nucleotide Mapping; Oligonucleotide Probes; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transcription Factors; Transcription, Genetic	1990
Inhibition of hydroxyl-radical-generated DNA degradation by metallothionein. Toxicology letters, 1989, Volume: 47, Issue:2 Topics: Catalase; DNA; DNA Damage; Electrophoresis, Agar Gel; Free Radicals; Glutathione; Hydroxides; Hydroxyl Radical; Metallothionein; Superoxide Dismutase	1989
ESR investigations at low temperatures of oxygen radical interaction with rat chromochelatin and metallothioneins. Biochemical and biophysical research communications, 1982, Sep-30, Volume: 108, Issue:2 Topics: Animals; Carrier Proteins; Electron Spin Resonance Spectroscopy; Gamma Rays; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Kidney; Liver; Metalloproteins; Metallothionein; Oxygen; Rats; Superoxides	1982
Mechanism of gentamicin nephrotoxicity in rats and the protective effect of zinc-induced metallothionein synthesis. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1994, Volume: 9 Suppl 4 Topics: Acute Kidney Injury; Animals; DNA; Free Radicals; Gentamicins; Hydroxyl Radical; In Vitro Techniques; Kidney; Kidney Cortex; Kidney Tubular Necrosis, Acute; Kidney Tubules, Proximal; Male; Metallothionein; Rats; Rats, Wistar; Reactive Oxygen Species; Sodium-Potassium-Exchanging ATPase; Zinc	1994
Zinc-induced metallothionein synthesis could protect from gentamicin nephrotoxicity in suspended proximal tubules of rats. Renal failure, 1994, Volume: 16, Issue:1 Topics: Animals; DNA; Free Radical Scavengers; Gentamicins; Hydroxyl Radical; Kidney Tubules, Proximal; Male; Malondialdehyde; Metallothionein; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Zinc	1994
A pulse radiolytic study on the reaction of hydroxyl and superoxide radicals with yeast Cu(I)-thionein. Biochimica et biophysica acta, 1993, Nov-10, Volume: 1203, Issue:1 Topics: Binding Sites; Carrier Proteins; Free Radicals; Glutathione; Hydroxyl Radical; Metallothionein; Models, Chemical; Organometallic Compounds; Pulse Radiolysis; Saccharomyces cerevisiae; Superoxides	1993
Metallothionein protects DNA from oxidative damage. The Biochemical journal, 1993, Apr-01, Volume: 291 ( Pt 1) Topics: Animals; Antioxidants; Cell Line; Cell Nucleus; Cricetinae; Cricetulus; DNA; DNA Damage; Free Radical Scavengers; Gene Expression; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Metallothionein; Promoter Regions, Genetic; RNA, Antisense; RNA, Messenger; Simian virus 40; Transfection; Zinc	1993
Production of hydroxyl radicals by copper-containing metallothionein: roles as prooxidant. Toxicology and applied pharmacology, 1996, Volume: 141, Issue:1 Topics: Animals; Copper; Hydrogen Peroxide; Hydroxyl Radical; Liver; Male; Metallothionein; Oxidation-Reduction; Rats; Rats, Wistar; Spectrophotometry, Atomic; Zinc	1996
Metal-induced hydroxyl radical generation by Cu(+)-metallothioneins from LEC rat liver. Biochemical and biophysical research communications, 1997, Feb-24, Volume: 231, Issue:3 Topics: Animals; Catalase; Copper; Electron Spin Resonance Spectroscopy; Hydroxyl Radical; Liver; Metallothionein; Oxidation-Reduction; Rats; Superoxide Dismutase	1997
Conversion of nitroxide radicals by phenolic and thiol antioxidants. Free radical research, 1997, Volume: 27, Issue:1 Topics: Antioxidants; Chromans; Cyclic N-Oxides; Cysteine; Dimethyl Sulfoxide; Electron Spin Resonance Spectroscopy; Ethanol; Free Radical Scavengers; Free Radicals; Glutathione; Hydroxyl Radical; Mercaptoethanol; Metallothionein; Nitrogen Oxides; Phenols; Sulfhydryl Compounds	1997
Free radical scavenging actions of metallothionein isoforms I and II. Free radical research, 1998, Volume: 29, Issue:2 Topics: Animals; Bepridil; Biphenyl Compounds; Chromatography, High Pressure Liquid; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Hydroxyl Radical; Liver; Male; Metallothionein; Oxygen; Picrates; Rats; Rats, Sprague-Dawley; Singlet Oxygen; Superoxides; Zinc	1998
The expressed alpha domain of mouse metallothionein-I from Escherichia coli displays independent structure and function. Biochemistry and molecular biology international, 1998, Volume: 46, Issue:2 Topics: Amino Acids; Animals; Cadmium; Circular Dichroism; Cloning, Molecular; Cytochrome c Group; Dithionitrobenzoic Acid; Escherichia coli; Free Radical Scavengers; Hydrogen-Ion Concentration; Hydroxyl Radical; Metallothionein; Mice; Microscopy, Atomic Force; Molecular Weight; Recombinant Fusion Proteins; Spectrophotometry, Ultraviolet; Zinc	1998
Protection of DNA in HL-60 cells from damage generated by hydroxyl radicals produced by reaction of H2O2 with cell iron by zinc-metallothionein. Chemico-biological interactions, 1998, Sep-04, Volume: 115, Issue:2 Topics: Antioxidants; Cell Nucleus; Cell Survival; Cesium Radioisotopes; Chlorides; DNA Damage; DNA, Single-Stranded; Free Radical Scavengers; Gamma Rays; HL-60 Cells; Humans; Hydrogen Peroxide; Hydroxyl Radical; Iron; Metallothionein; Zinc Compounds	1998
Metallothionein isoforms provide neuroprotection against 6-hydroxydopamine-generated hydroxyl radicals and superoxide anions. Proceedings of the Western Pharmacology Society, 1998, Volume: 41 Topics: Animals; Anions; Brain; Cells, Cultured; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Hydroxyl Radical; Metallothionein; Mice; Mitochondria; Neuroprotective Agents; Oxidopamine; Protein Isoforms; Spin Labels; Superoxides	1998
Evidence that the reactions of cadmium in the presence of metallothionein can produce hydroxyl radicals. Archives of toxicology, 1998, Volume: 72, Issue:11 Topics: Cadmium; Copper; Cyclic N-Oxides; DNA Damage; Dose-Response Relationship, Drug; Drug Interactions; Electron Spin Resonance Spectroscopy; Hydroxyl Radical; Lipid Peroxidation; Metallothionein; Reproducibility of Results	1998
Redox regulation of copper-metallothionein. Archives of biochemistry and biophysics, 1999, Mar-01, Volume: 363, Issue:1 Topics: Animals; Antioxidants; Ascorbic Acid; Cell Survival; Cell-Free System; Copper; Cytoprotection; Dehydroascorbic Acid; Electron Spin Resonance Spectroscopy; HL-60 Cells; Humans; Hydrogen Peroxide; Hydroxyl Radical; Lipid Peroxidation; Metallothionein; Oxidation-Reduction; Oxidative Stress; Rabbits	1999
Free radical scavenging actions of hippocampal metallothionein isoforms and of antimetallothioneins: an electron spin resonance spectroscopic study. Cellular and molecular biology (Noisy-le-Grand, France), 2000, Volume: 46, Issue:3 Topics: Animals; Bepridil; Biphenyl Compounds; Cells, Cultured; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Hippocampus; Hydroxyl Radical; Male; Metallothionein; Picrates; Piperidones; Protein Isoforms; Rats; Rats, Sprague-Dawley; Superoxides; tert-Butylhydroperoxide; Triacetoneamine-N-Oxyl	2000
Reconstitution of apo-superoxide dismutase by nitric oxide-induced copper transfer from metallothioneins. Chemical research in toxicology, 2000, Volume: 13, Issue:9 Topics: Animals; Ascorbic Acid; Azetidines; Copper; Electrophoresis, Polyacrylamide Gel; Hydroxyl Radical; Metallothionein; Molecular Chaperones; Nitric Oxide; Nitric Oxide Donors; Rabbits; Superoxide Dismutase; Zinc	2000
Reduction of metallothioneins promotes the disease expression of familial amyotrophic lateral sclerosis mice in a dose-dependent manner. The European journal of neuroscience, 2001, Volume: 13, Issue:7 Topics: Amyotrophic Lateral Sclerosis; Animals; Copper; Disease Models, Animal; Gene Dosage; Gene Expression Regulation, Enzymologic; Humans; Hydroxyl Radical; Metallothionein; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Transgenic; Oxidative Stress; Spinal Cord; Superoxide Dismutase	2001
Cu-metallothioneins (Cu(I)8-MTs) in LEC rat livers 13 weeks after birth still act as antioxidants. Archives of biochemistry and biophysics, 2001, Mar-15, Volume: 387, Issue:2 Topics: Animals; Antioxidants; Binding, Competitive; Cadmium Chloride; Copper; Cyclic N-Oxides; Cytosol; DNA; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Glutathione; Hepatolenticular Degeneration; Hydroxyl Radical; Liver; Male; Mercuric Chloride; Metallothionein; Oxidation-Reduction; Rats; Rats, Inbred LEC; Reactive Oxygen Species; Superoxide Dismutase	2001
Protective effect of metallothionein-III on DNA damage in response to reactive oxygen species. Biochimica et biophysica acta, 2002, Oct-10, Volume: 1573, Issue:1 Topics: DNA Damage; Edetic Acid; Ethidium; Ethylmaleimide; Fluorescence; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hydroxyl Radical; Metallothionein; Metallothionein 3; Nerve Tissue Proteins; Neuroprotective Agents; Nitrilotriacetic Acid; Plasmids; Recombinant Proteins	2002
A protective role for zinc on intestinal peroxidative damage during oral iron repletion. Biochemical and biophysical research communications, 2004, Jun-11, Volume: 318, Issue:4 Topics: Aconitate Hydratase; Administration, Oral; Animals; Catalase; Cytosol; Electron Spin Resonance Spectroscopy; Female; Glutathione Peroxidase; Hemoglobins; Hydroxyl Radical; Intestinal Mucosa; Iron; Iron Deficiencies; Lipid Peroxidation; Liver; Metallothionein; Protective Agents; Rats; Rats, Inbred WKY; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Zinc	2004
Potent hydroxyl radical-scavenging activity of drought-induced type-2 metallothionein in wild watermelon. Biochemical and biophysical research communications, 2004, Oct-08, Volume: 323, Issue:1 Topics: Amino Acid Sequence; Arabidopsis Proteins; Catalysis; Citrullus; Cloning, Molecular; Disasters; DNA; DNA, Complementary; Dose-Response Relationship, Drug; Gene Expression Profiling; Hydroxyl Radical; Metallothionein; Molecular Sequence Data; Oxidative Stress; Phylogeny; Plant Proteins; Recombinant Proteins; RNA; RNA, Messenger; Sequence Homology, Amino Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors	2004
Effect of pressure on pulse radiolysis reduction of proteins. Biochimica et biophysica acta, 2005, Aug-05, Volume: 1724, Issue:3 Topics: Animals; Bivalvia; Hydroxyl Radical; Metallothionein; Myoglobin; Oxidation-Reduction; Pressure; Pulse Radiolysis; Superoxides	2005
Susceptibility to oxidative stress of mussels (Mytilus galloprovincialis) in the Venice Lagoon (Italy). Marine pollution bulletin, 2005, Volume: 50, Issue:12 Topics: Animals; Biomarkers; Catalase; Environmental Monitoring; Free Radical Scavengers; Hemolymph; Hydroxyl Radical; Italy; Malondialdehyde; Metallothionein; Mytilus; Oxidative Stress; Peroxides; Peroxynitrous Acid; Principal Component Analysis; Statistics as Topic	2005
Use of the land snail Helix aspersa as sentinel organism for monitoring ecotoxicologic effects of urban pollution: an integrated approach. Environmental health perspectives, 2006, Volume: 114, Issue:1 Topics: Air Pollutants; Animals; Cities; DNA Damage; Environmental Monitoring; Environmental Pollution; Gastrointestinal Tract; Helix, Snails; Hydroxyl Radical; Italy; Metallothionein; Metals, Heavy; Peroxides; Polycyclic Aromatic Hydrocarbons; Vehicle Emissions	2006
The role of Thr5 in human neuron growth inhibitory factor. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2006, Volume: 11, Issue:4 Topics: Animals; Base Sequence; Cell Survival; Cells, Cultured; Circular Dichroism; Dose-Response Relationship, Drug; Humans; Hydroxyl Radical; Mass Spectrometry; Metallothionein; Metallothionein 3; Mutant Proteins; Mutation; Nerve Tissue Proteins; Neurites; Neurons; Rats; Rats, Wistar; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Threonine	2006
Mechanism of DNA damage by cadmium and interplay of antioxidant enzymes and agents. Environmental toxicology, 2007, Volume: 22, Issue:2 Topics: Cadmium; Catalase; Chelating Agents; Dimethyl Sulfoxide; DNA; DNA Breaks, Single-Stranded; Edetic Acid; Ethanol; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Mannitol; Metallothionein; Oxidants; Plasmids; Superoxide Dismutase; Temperature	2007
Redox silencing of copper in metal-linked neurodegenerative disorders: reaction of Zn7metallothionein-3 with Cu2+ ions. The Journal of biological chemistry, 2007, Jun-01, Volume: 282, Issue:22 Topics: Alzheimer Disease; Amyloid beta-Peptides; Brain; Cations, Divalent; Circular Dichroism; Copper; Cytoprotection; Down-Regulation; Humans; Hydroxyl Radical; Metallothionein; Neurons; Oxidation-Reduction; Protein Binding; Recombinant Proteins; Spectrophotometry, Ultraviolet; Zinc	2007
HbMT2, an ethephon-induced metallothionein gene from Hevea brasiliensis responds to H(2)O(2) stress. Plant physiology and biochemistry : PPB, 2010, Volume: 48, Issue:8 Topics: Amino Acid Sequence; Base Sequence; Copper; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Free Radical Scavengers; Gene Expression Profiling; Gene Expression Regulation, Plant; Hevea; Hydrogen Peroxide; Hydroxyl Radical; Hydroxylation; Metallothionein; Molecular Sequence Data; Organophosphorus Compounds; Oxidants; Phylogeny; Plant Growth Regulators; Plant Proteins; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Salicylates; Sequence Homology, Amino Acid; Stress, Physiological; Zinc	2010
A combination of melatonin and alpha lipoic acid has greater cardioprotective effect than either of them singly against cadmium-induced oxidative damage. Cardiovascular toxicology, 2011, Volume: 11, Issue:1 Topics: Animals; Antioxidants; Ascorbic Acid; Biomarkers; Cadmium Chloride; Drug Synergism; Drug Therapy, Combination; Enzymes; Female; Glutathione; Heart Diseases; Hydrogen Peroxide; Hydroxyl Radical; Lipid Peroxidation; Malondialdehyde; Melatonin; Metallothionein; Myocardium; Oxidative Stress; Rats; Thioctic Acid; Vitamin E	2011
Time-dependent toxicity of cadmium telluride quantum dots on liver and kidneys in mice: histopathological changes with elevated free cadmium ions and hydroxyl radicals. International journal of nanomedicine, 2016, Volume: 11 Topics: Animals; Cadmium; Cadmium Compounds; Chromatography, High Pressure Liquid; Humans; Hydroxyl Radical; Immunohistochemistry; Ions; Kidney; Liver; Male; Metallothionein; Mice, Inbred ICR; Quantum Dots; Tellurium; Time Factors	2016