Compounds > hydroxyl radical
Page last updated: 2024-09-04

hydroxyl radical and kanamycin a

hydroxyl radical has been researched along with kanamycin a in 6 studies

Compound Research Comparison

Studies
(hydroxyl radical)		Trials
(hydroxyl radical)		Recent Studies (post-2010)
(hydroxyl radical)		Studies
(kanamycin a)		Trials
(kanamycin a)		Recent Studies (post-2010) (kanamycin a)
10,147263,6577,169187946

Protein Interaction Comparison

ProteinTaxonomyhydroxyl radical (IC50)kanamycin a (IC50)
3-oxoacyl-[acyl-carrier-protein] synthase 3Escherichia coli K-126.8
Gap junction beta-2 proteinHomo sapiens (human)9.4

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's3 (50.00)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Butterfield, DA; Clerici, WJ; DiMartino, DL; Hensley, K1
Lesniak, W; Schacht, J; Sha, SH; Wang, AM1
Wright, GD1
Collins, JJ; Dwyer, DJ; Hayete, B; Kohanski, MA; Lawrence, CA1
Collins, JJ; Devadoss, B; Foti, JJ; Walker, GC; Winkler, JA1
Chueca, B; García-Gonzalo, D; Pagán, R1

Other Studies

6 other study(ies) available for hydroxyl radical and kanamycin a

ArticleYear
Direct detection of ototoxicant-induced reactive oxygen species generation in cochlear explants.
    Hearing research, 1996, Sep-01, Volume: 98, Issue:1-2

    Topics: Analgesics, Non-Narcotic; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Cisplatin; Cochlea; Cyclic N-Oxides; Diuretics; Electron Spin Resonance Spectroscopy; Ethacrynic Acid; Female; Furosemide; Gentamicins; Guinea Pigs; Hydrogen Peroxide; Hydroxyl Radical; Kanamycin; Male; Perilymph; Quinine; Spin Labels; Trimethyltin Compounds

1996
Tanshinone (Salviae miltiorrhizae extract) preparations attenuate aminoglycoside-induced free radical formation in vitro and ototoxicity in vivo.
    Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:6

    Topics: Abietanes; Animals; Anti-Bacterial Agents; Auditory Threshold; Cochlea; Drug Interactions; Drugs, Chinese Herbal; Evoked Potentials, Auditory, Brain Stem; Free Radical Scavengers; Gentamicins; Hearing Loss; Hydroxyl Radical; Kanamycin; Lipid Peroxidation; Male; Mice; Mice, Inbred CBA; Oxidants; Phenanthrenes; Superoxides

2003
On the road to bacterial cell death.
    Cell, 2007, Sep-07, Volume: 130, Issue:5

    Topics: Ampicillin; Anti-Bacterial Agents; Carbon-Sulfur Lyases; Cell Death; Citric Acid Cycle; DNA Damage; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Ferrous Compounds; Gene Expression Regulation, Bacterial; Hydrogen Peroxide; Hydroxyl Radical; Kanamycin; Membrane Proteins; Microbial Viability; Mutation; NAD; Norfloxacin; Oxidative Stress; Rec A Recombinases; Staphylococcus aureus; Time Factors

2007
A common mechanism of cellular death induced by bactericidal antibiotics.
    Cell, 2007, Sep-07, Volume: 130, Issue:5

    Topics: 2,2'-Dipyridyl; Ampicillin; Anti-Bacterial Agents; Carbon-Sulfur Lyases; Cell Death; Citric Acid Cycle; Colony Count, Microbial; DNA Damage; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Ferrous Compounds; Free Radical Scavengers; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Hydrogen Peroxide; Hydroxyl Radical; Hydroxyurea; Iron Chelating Agents; Kanamycin; Membrane Proteins; Microbial Viability; Mutation; NAD; Norfloxacin; Oxidative Stress; Rec A Recombinases; Staphylococcus aureus; Time Factors

2007
Oxidation of the guanine nucleotide pool underlies cell death by bactericidal antibiotics.
    Science (New York, N.Y.), 2012, Apr-20, Volume: 336, Issue:6079

    Topics: Ampicillin; Anti-Bacterial Agents; Deoxyguanine Nucleotides; DNA Breaks, Double-Stranded; DNA Glycosylases; DNA Polymerase beta; DNA Polymerase I; DNA Polymerase II; DNA-Directed DNA Polymerase; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Guanine; Guanine Nucleotides; Hydroxyl Radical; Kanamycin; Microbial Viability; Models, Biological; Norfloxacin; Oxidation-Reduction; Pyrophosphatases; RNA, Bacterial

2012
Differential mechanism of Escherichia coli Inactivation by (+)-limonene as a function of cell physiological state and drug's concentration.
    PloS one, 2014, Volume: 9, Issue:4

    Topics: Citric Acid Cycle; Cyclohexenes; Dose-Response Relationship, Drug; Escherichia coli; Free Radical Scavengers; Hydroxyl Radical; Iron; Kanamycin; Limonene; Terpenes

2014