hydroxyl radical has been researched along with kainic acid in 11 studies
| Studies (hydroxyl radical) | Trials (hydroxyl radical) | Recent Studies (post-2010) (hydroxyl radical) | Studies (kainic acid) | Trials (kainic acid) | Recent Studies (post-2010) (kainic acid) |
|---|---|---|---|---|---|
| 10,147 | 26 | 3,657 | 9,540 | 3 | 1,775 |
| Protein | Taxonomy | hydroxyl radical (IC50) | kainic acid (IC50) |
|---|---|---|---|
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | 4.2857 | |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | 4.2857 | |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | 4.2857 | |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | 4.2857 | |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | 0.0126 | |
| Glutamate receptor ionotropic, kainate 1 | Homo sapiens (human) | 0.077 | |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | 0.0126 | |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | 0.0126 | |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | 0.0126 | |
| Glutamate receptor ionotropic, kainate 2 | Homo sapiens (human) | 0.077 | |
| Glutamate receptor ionotropic, kainate 3 | Homo sapiens (human) | 0.077 | |
| Glutamate receptor ionotropic, kainate 4 | Homo sapiens (human) | 0.077 | |
| Glutamate receptor ionotropic, kainate 5 | Homo sapiens (human) | 0.077 | |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | 0.0126 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dykens, JA; Stern, A; Trenkner, E | 1 |
| Beal, MF; Cipolloni, PB; Ferrante, RJ; Henshaw, DR; Jenkins, BG; Kowall, NW; Rosen, BR; Schulz, JB; Siwek, D | 1 |
| Cutler, RC; Joseph, JA | 1 |
| Ayata, C; Ayata, G; Beal, MF; Christie, RH; Endres, M; Ferrante, RJ; Hara, H; Huang, PL; Hyman, BT; Kim, A; Matthews, RT; Moskowitz, MA; Waeber, C | 1 |
| Mohanan, PV; Yamamoto, HA | 2 |
| Cheng, H; Fu, YS; Guo, JW | 1 |
| Ballini, C; Colivicchi, MA; Della Corte, L; Fattori, M; Freinbichler, W; Linert, W; Tipton, KF | 1 |
| Cooper, WJ; Jones, KG; Mezykk, SP | 1 |
| Chung, CK; Chung, YH; Jeong, JH; Kim, DJ; Kim, HC; Kim, HJ; Lee, SY; Nam, Y; Ong, WY; Park, ES; Shin, EJ; Tran, TV; Wie, MB | 1 |
| Mitch, WA; Parker, KM | 1 |
1 review(s) available for hydroxyl radical and kainic acid
| Article | Year |
|---|---|
The role of oxidative stress in signal transduction changes and cell loss in senescence.
Topics: Aging; Animals; Antioxidants; Brain; Brain Diseases; Cyclic N-Oxides; Free Radicals; Humans; Hydroxyl Radical; Kainic Acid; Neurons; Nitrogen Oxides; Oxidative Stress; Signal Transduction; Spin Labels | 1994 |
10 other study(ies) available for hydroxyl radical and kainic acid
| Article | Year |
|---|---|
Mechanism of kainate toxicity to cerebellar neurons in vitro is analogous to reperfusion tissue injury.
Topics: Allopurinol; Animals; Cell Survival; Cells, Cultured; Cerebellum; Endopeptidases; Hydroxides; Hydroxyl Radical; Ischemia; Kainic Acid; Mannitol; Mice; NADPH Dehydrogenase; Nervous System Diseases; Neurons; Perfusion; Protease Inhibitors; Serine Endopeptidases; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1987 |
Involvement of free radicals in excitotoxicity in vivo.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Cell Death; Cells, Cultured; Cyclic N-Oxides; Dizocilpine Maleate; Electrophysiology; Free Radical Scavengers; Free Radicals; Hydroxyl Radical; Kainic Acid; Male; N-Methylaspartate; Neurons; Nitrogen Oxides; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 1995 |
Mechanisms of reduced striatal NMDA excitotoxicity in type I nitric oxide synthase knock-out mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Binding Sites; Corpus Striatum; Dizocilpine Maleate; DNA Fragmentation; Excitatory Amino Acid Antagonists; Hydroxyl Radical; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Nitric Oxide Synthase; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Tyrosine | 1997 |
Preventive effect of melatonin against DNA damage induced by cyanide, kainate, glutathione/Fe(3+)/O(2), or H(2)O(2)/Fe(2+).
Topics: Animals; Brain; DNA; DNA Damage; Dose-Response Relationship, Drug; Glutathione; Hydrogen Peroxide; Hydroxyl Radical; Iron; Kainic Acid; Lipid Peroxidation; Male; Melatonin; Mice; Mice, Inbred Strains; Potassium Cyanide | 2001 |
Preventive effect of melatonin against brain mitochondria DNA damage, lipid peroxidation and seizures induced by kainic acid.
Topics: Animals; Brain; DNA Damage; DNA, Mitochondrial; Free Radical Scavengers; Hydroxyl Radical; Kainic Acid; Lipid Peroxidation; Male; Melatonin; Mice; Seizures | 2002 |
Ability of GDNF to diminish free radical production leads to protection against kainate-induced excitotoxicity in hippocampus.
Topics: Animals; Free Radical Scavengers; Free Radicals; Glial Cell Line-Derived Neurotrophic Factor; Glutathione Peroxidase; Hippocampus; Hydroxyl Radical; Kainic Acid; Male; Nerve Growth Factors; Neurons; Neuroprotective Agents; Neurotoxins; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reaction Time; Superoxide Dismutase | 2004 |
Validation of a robust and sensitive method for detecting hydroxyl radical formation together with evoked neurotransmitter release in brain microdialysis.
Topics: Amino Acids; Animals; Brain; Brain Chemistry; Dose-Response Relationship, Drug; Fluorescence; Hydroxyl Radical; Iron; Kainic Acid; Male; Microdialysis; Neurochemistry; Neurotoxins; Neurotransmitter Agents; o-Phthalaldehyde; Phthalic Acids; Rats; Rats, Wistar; Reactive Oxygen Species; Synaptic Transmission | 2008 |
Bimolecular rate constant determination for the reaction of hydroxyl radicals with domoic and kainic acid in aqueous solution.
Topics: Hydroxyl Radical; Kainic Acid; Models, Chemical; Molecular Structure; Oxidation-Reduction; Solutions; Water Pollutants, Chemical | 2009 |
Ceruloplasmin is an endogenous protectant against kainate neurotoxicity.
Topics: Adolescent; Adult; Animals; CA1 Region, Hippocampal; Case-Control Studies; Ceruloplasmin; Epilepsy; Female; Glutathione; Humans; Hydroxyl Radical; Kainic Acid; Lipid Peroxidation; Male; Middle Aged; Oxidative Stress; Rats, Sprague-Dawley; Young Adult | 2015 |
Halogen radicals contribute to photooxidation in coastal and estuarine waters.
Topics: Carbonates; Estuaries; Fresh Water; Halogens; Harmful Algal Bloom; Hydroxyl Radical; Iron; Kainic Acid; Kinetics; Light; Marine Toxins; Nitrates; Photolysis; Seawater; Sulfides | 2016 |