Page last updated: 2024-09-04

hydroxyl radical and ibuprofen

hydroxyl radical has been researched along with ibuprofen in 17 studies

Compound Research Comparison

Studies
(hydroxyl radical)
Trials
(hydroxyl radical)
Recent Studies (post-2010)
(hydroxyl radical)
Studies
(ibuprofen)
Trials
(ibuprofen)
Recent Studies (post-2010) (ibuprofen)
10,147263,65710,2451,7814,267

Protein Interaction Comparison

ProteinTaxonomyhydroxyl radical (IC50)ibuprofen (IC50)
Prostaglandin G/H synthase 1 Bos taurus (cattle)2.9
Prostaglandin G/H synthase 2 Bos taurus (cattle)1.1
AlbuminBos taurus (cattle)3
Prostaglandin G/H synthase 1Ovis aries (sheep)4.0919
Prostaglandin G/H synthase 1Mus musculus (house mouse)0.22
Prostaglandin G/H synthase 1Homo sapiens (human)1.6273
Caspase-1Homo sapiens (human)7.2667
Substance-P receptorCavia porcellus (domestic guinea pig)1.1
Prostaglandin G/H synthase 2Homo sapiens (human)3.0687
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)1.3
Aldo-keto reductase family 1 member C3Homo sapiens (human)10
Caspase-3Homo sapiens (human)7.2667
Caspase-4Homo sapiens (human)7.2667
4-aminobutyrate aminotransferase, mitochondrialRattus norvegicus (Norway rat)1.1
Caspase-5Homo sapiens (human)7.2667
Caspase-9Homo sapiens (human)7.2667
Prostaglandin G/H synthase 2Ovis aries (sheep)1.1375
Mu-type opioid receptorCavia porcellus (domestic guinea pig)2.9
Fatty-acid amide hydrolase 1Rattus norvegicus (Norway rat)5
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.54
Solute carrier family 22 member 6Homo sapiens (human)8
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)1.3

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.88)18.7374
1990's3 (17.65)18.2507
2000's0 (0.00)29.6817
2010's11 (64.71)24.3611
2020's2 (11.76)2.80

Authors

AuthorsStudies
Hamburger, SA; McCay, PB1
Gurtner, GH; Hoidal, JR; Jafri, MH; Kennedy, TP; Michael, JR; Noah, W; Rao, NV1
Caplan, M; Hess, ML; Lucchesi, B; Romson, JL; Rowe, GT1
Althaus, JS; Andrus, PK; Hall, ED; VonVoigtlander, PF1
Lee, Y; von Gunten, U1
Gin, KY; Nguyen, TV; Reinhard, M; Xu, Y1
De Laurentiis, E; Kouras, S; Maddigapu, PR; Maurino, V; Minella, M; Minero, C; Pazzi, M; Richard, C; Vione, D1
Lin, YP; Yong, EL1
Dombi, A; Gajda-Schrantz, K; Gonter, K; Illés, E; Rácz, G; Takács, E; Wojnárovits, L1
Im, JK; Yoon, Y; Zoh, KD1
Feng, L; Li, L; Qi, F; Wang, H; Wang, X; Zhang, L1
Chehrenegar, B; Hu, J; Ong, SL1
Fang, J; Shang, C; Xiang, Y1
Banaschik, R; Bednarski, PJ; Jablonowski, H; Kolb, JF1
Darvishi Cheshmeh Soltani, R; Mashayekhi, M1
Cho, S; Hwang, I; Kim, C1
Kang, C; Li, J; Li, M; Liu, B; Xue, H; Zhang, G1

Other Studies

17 other study(ies) available for hydroxyl radical and ibuprofen

ArticleYear
Spin trapping of ibuprofen radicals: evidence that ibuprofen is a hydroxyl radical scavenger.
    Free radical research communications, 1990, Volume: 9, Issue:3-6

    Topics: Antioxidants; Electron Spin Resonance Spectroscopy; Free Radicals; Hydroxides; Hydroxyl Radical; Ibuprofen

1990
Ibuprofen prevents oxidant lung injury and in vitro lipid peroxidation by chelating iron.
    The Journal of clinical investigation, 1990, Volume: 86, Issue:5

    Topics: Animals; Chlorides; Ferric Compounds; Hydroxides; Hydroxyl Radical; Ibuprofen; Iron Chelating Agents; Lipid Peroxidation; Lung; Oxidation-Reduction; Perfusion; Phosgene; Prostaglandin-Endoperoxide Synthases; Rabbits

1990
Identification of hydrogen peroxide and hydroxyl radicals as mediators of leukocyte-induced myocardial dysfunction. Limitation of infarct size with neutrophil inhibition and depletion.
    Advances in myocardiology, 1985, Volume: 5

    Topics: Adenosine Triphosphatases; Animals; Butylated Hydroxytoluene; Calcium; Catalase; Dogs; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Ibuprofen; Indomethacin; Leukocytes; Male; Mannitol; Myocardial Infarction; Myocardium; Neutrophils; Sarcoplasmic Reticulum; Superoxide Dismutase; Tetradecanoylphorbol Acetate

1985
Hydroxyl radical production and lipid peroxidation parallels selective post-ischemic vulnerability in gerbil brain.
    Journal of neuroscience research, 1993, Volume: 34, Issue:1

    Topics: Animals; Brain; Brain Ischemia; Cerebral Cortex; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Free Radicals; Gentisates; Gerbillinae; Hippocampus; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Ibuprofen; Lipid Peroxides; Male; Proadifen; Reperfusion; Salicylates; Salicylic Acid; Vitamin E

1993
Oxidative transformation of micropollutants during municipal wastewater treatment: comparison of kinetic aspects of selective (chlorine, chlorine dioxide, ferrate VI, and ozone) and non-selective oxidants (hydroxyl radical).
    Water research, 2010, Volume: 44, Issue:2

    Topics: Ammonia; Atenolol; Bromides; Carbamazepine; Chlorine; Chlorine Compounds; Efficiency; Ethinyl Estradiol; Fresh Water; Hydroxyl Radical; Ibuprofen; Iron; Kinetics; Nitrites; Organic Chemicals; Oxidants; Oxidation-Reduction; Oxides; Ozone; Sulfamethoxazole; Waste Disposal, Fluid; Water Pollutants, Chemical

2010
Photodegradation kinetics of p-tert-octylphenol, 4-tert-octylphenoxy-acetic acid and ibuprofen under simulated solar conditions in surface water.
    Chemosphere, 2011, Volume: 85, Issue:5

    Topics: Acetic Acid; Analgesics, Non-Narcotic; Humic Substances; Hydrogen Peroxide; Hydroxyl Radical; Ibuprofen; Kinetics; Phenols; Photolysis; Sunlight; Surface-Active Agents; Water

2011
Modelling the photochemical fate of ibuprofen in surface waters.
    Water research, 2011, Dec-15, Volume: 45, Issue:20

    Topics: Absorption; Anthraquinones; Hydrogen-Ion Concentration; Hydroxyl Radical; Ibuprofen; Kinetics; Models, Chemical; Photochemistry; Photolysis; Riboflavin; Rose Bengal; Superoxides; Surface Properties; Ultraviolet Rays; Water Pollutants, Chemical

2011
Incorporation of initiation, promotion and inhibition in the Rct concept and its application in determining the initiation and inhibition capacities of natural water in ozonation.
    Water research, 2012, Apr-15, Volume: 46, Issue:6

    Topics: Alkalies; Formates; Hydrogen-Ion Concentration; Hydroxyl Radical; Ibuprofen; Methanol; Models, Chemical; Ozone; Singapore; tert-Butyl Alcohol; Water; Water Pollutants, Chemical; Water Purification

2012
Hydroxyl radical induced degradation of ibuprofen.
    The Science of the total environment, 2013, Mar-01, Volume: 447

    Topics: Aliivibrio fischeri; Animals; Chromatography, High Pressure Liquid; Daphnia; Ecotoxicology; Gamma Rays; Hydroxyl Radical; Hydroxylation; Ibuprofen; Luminescence; Mass Spectrometry; Pulse Radiolysis; Solutions; Spectrophotometry, Ultraviolet; Water Pollutants, Chemical

2013
Optimization of naproxen and ibuprofen removal in photolysis using a Box-Behnken design: effect of Fe(III), NO3-, and humic acid.
    Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 2014, Volume: 49, Issue:4

    Topics: Humic Substances; Hydroxyl Radical; Ibuprofen; Iron; Kinetics; Models, Theoretical; Naproxen; Nitrates; Photolysis; Regression Analysis; Ultraviolet Rays; Water Pollutants, Chemical; Water Purification

2014
Removal performance and mechanism of ibuprofen from water by catalytic ozonation using sludge-corncob activated carbon as catalyst.
    Journal of nanoscience and nanotechnology, 2014, Volume: 14, Issue:9

    Topics: Carbon; Hydrogen Peroxide; Hydroxyl Radical; Ibuprofen; Kinetics; Ozone; Sewage; Water Pollutants, Chemical; Water Purification; Zea mays

2014
Active removal of ibuprofen by Money plant enhanced by ferrous ions.
    Chemosphere, 2016, Volume: 144

    Topics: Araceae; Biodegradation, Environmental; Hydrogen Peroxide; Hydroxyl Radical; Ibuprofen; Iron; Oxidation-Reduction; Water Pollutants, Chemical

2016
Kinetics and pathways of ibuprofen degradation by the UV/chlorine advanced oxidation process.
    Water research, 2016, Mar-01, Volume: 90

    Topics: Chlorine; Disinfection; Drinking Water; Halogenation; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxyl Radical; Ibuprofen; Kinetics; Oxygen; Photochemistry; Temperature; Ultraviolet Rays; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Purification

2016
Degradation and intermediates of diclofenac as instructive example for decomposition of recalcitrant pharmaceuticals by hydroxyl radicals generated with pulsed corona plasma in water.
    Journal of hazardous materials, 2018, Jan-15, Volume: 342

    Topics: Carbamazepine; Diclofenac; Electron Spin Resonance Spectroscopy; Ethinyl Estradiol; Hydrogen Peroxide; Hydroxyl Radical; Ibuprofen; Water

2018
Decomposition of ibuprofen in water via an electrochemical process with nano-sized carbon black-coated carbon cloth as oxygen-permeable cathode integrated with ultrasound.
    Chemosphere, 2018, Volume: 194

    Topics: Carbon; Electrochemical Techniques; Electrodes; Hydrogen Peroxide; Hydroxyl Radical; Ibuprofen; Kinetics; Models, Theoretical; Nanoparticles; Oxygen; Sonication; Soot; Water Pollutants, Chemical; Water Purification

2018
Electrochemical degradation of ibuprofen using an activated-carbon-based continuous-flow three-dimensional electrode reactor (3DER).
    Chemosphere, 2020, Volume: 259

    Topics: Charcoal; Electrodes; Hydroxyl Radical; Ibuprofen; Kinetics; Oxidation-Reduction; Water; Water Pollutants, Chemical; Water Purification

2020
Hydroxyl radical dominated ibuprofen degradation by UV/percarbonate process: Response surface methodology optimization, toxicity, and cost evaluation.
    Chemosphere, 2023, Volume: 329

    Topics: Carbonates; Hydroxyl Radical; Ibuprofen; Oxidation-Reduction; Reactive Oxygen Species; Ultraviolet Rays; Water Pollutants, Chemical; Water Purification

2023