hydroxyl radical has been researched along with guanine in 59 studies
| Studies (hydroxyl radical) | Trials (hydroxyl radical) | Recent Studies (post-2010) (hydroxyl radical) | Studies (guanine) | Trials (guanine) | Recent Studies (post-2010) (guanine) |
|---|---|---|---|---|---|
| 10,147 | 26 | 3,657 | 16,278 | 822 | 4,809 |
| Protein | Taxonomy | hydroxyl radical (IC50) | guanine (IC50) |
|---|---|---|---|
| Purine nucleoside phosphorylase | Homo sapiens (human) | 5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.69) | 18.7374 |
| 1990's | 14 (23.73) | 18.2507 |
| 2000's | 21 (35.59) | 29.6817 |
| 2010's | 20 (33.90) | 24.3611 |
| 2020's | 3 (5.08) | 2.80 |
| Authors | Studies |
|---|---|
| Churchill, ME; Hayes, JJ; Tullius, TD | 1 |
| Eneff, K; Floyd, RA; Gutteridge, JM; West, M | 1 |
| Eneff, KL; Floyd, RA; Hogsett, WE; Tingey, DT; West, MS | 1 |
| Aruoma, OI; Chimel, K; Cross, CE; Halliwell, B; Jenner, A; Spencer, JP; Wu, R | 1 |
| Bailly, C; Møllegaard, NE; Nielsen, PE; Waring, MJ | 1 |
| Ballmaier, D; Epe, B | 1 |
| Carpenter, ML; Cassidy, SA; Fox, KR | 1 |
| Dalal, N; Ding, M; Gannett, PM; Knapton, AD; Liu, K; Mao, Y; Rojanasakul, Y; Shi, X | 1 |
| Floyd, RA; Maidt, ML; Phillips, JR; Price, S; Pye, Q; Schneider, JE | 1 |
| Schulz, WA; Sies, H; Steenken, S | 1 |
| Adam, W; Andler, S; Saha-Möller, CR; Schönberger, A | 1 |
| Alam, ZI; Cairns, N; Daniel, SE; Halliwell, B; Jenner, A; Jenner, P; Lees, AJ; Marsden, CD | 1 |
| Zastawny, TH | 1 |
| Bechara, EJ; Cadet, J; Di Mascio, P; Douki, T; Medeiros, MH; Onuki, J | 1 |
| Akiyama, K; Aoyagi, K; Ienaga, K; Koyama, A; Kuzure, Y; Nagase, S; Nakamura, K; Narita, M; Takemura, K | 1 |
| Bretonniere, Y; Cadet, J; Douki, T | 1 |
| La, DK; Nakamura, J; Swenberg, JA | 1 |
| Candeias, LP; Steenken, S | 1 |
| Hazen, SL; Shen, Z; Wu, W | 1 |
| Acero, JL; Canonica, S; Eggen, RI; Schweigert, N; von Gunten, U; Zehnder, AJ | 1 |
| Malins, DC; Ostrander, GK; Polissar, NL; Vinson, MA | 1 |
| Aguilera, JA; Milligan, JR; Nguyen, JV; Ward, JF | 1 |
| Choi, JY; Chung, MH; Doetsch, PW; Kim, JE; Kim, JS; You, HJ | 1 |
| Barker, EA; Johnson, PM; Malins, DC; Polissar, NL; Vinson, MA; Wheeler, TM | 1 |
| Anastassopoulou, J; Theophanides, T | 1 |
| González, A; Kosinski, C; Kurbanyan, K; Lueras, AM; Mah, DA; Nguyen, KL; Rivas, EV; Stemp, ED; Steryo, M; To, P | 1 |
| Cadet, J; Douki, T; Gasparutto, D; Ravanat, JL | 1 |
| Gao, X; Gershon, PD; Li, C; Xia, Y | 1 |
| Jena, NR; Mishra, PC | 1 |
| Eriksson, LA; Zhang, Rb | 1 |
| Jeong, HG; Lee, KJ | 1 |
| Bruskov, VI; Chernikov, AV; Gudkov, SV; Shtarkman, IN | 1 |
| Barone, V; Cadet, J; Cimino, P; Grand, A; Labet, V; Morell, C | 1 |
| Chatgilialoglu, C; D'Angelantonio, M; Guerra, M; Kaloudis, P; Mulazzani, QG | 1 |
| Abolfath, RM | 1 |
| Andrievsky, GV; Bruskov, VI; Gudkov, SV; Tykhomyrov, AA | 1 |
| Gilant, E; Nowicka, AM; Stojek, Z; Zabost, E | 1 |
| Cadet, J; Douki, T | 1 |
| Naumov, S; Phadatare, SD; Rao, BS; Sharma, GK; Sharma, KK | 1 |
| Kumar, A; Pottiboyina, V; Sevilla, MD | 1 |
| Abolfath, RM; Biswas, PK; Brabec, T; Kodym, R; Papiez, L; Rajnarayanam, R | 1 |
| Collins, JJ; Devadoss, B; Foti, JJ; Walker, GC; Winkler, JA | 1 |
| Geacintov, NE; Liu, Y; Liu, Z; Shafirovich, V | 1 |
| Gu, X; Li, H; Li, P; Liu, J; Meng, F; Wang, L; Yue, Q; Zhang, S; Zhang, W; Zhao, J | 1 |
| Berezhnov, AV; Bruskov, VI; Chernikov, AV; Garmash, SA; Gudkov, SV; Ivanov, VE; Karp, OE; Smirnova, VS; Usacheva, AM | 1 |
| Chen, J; Gai, P; Yang, Y; Zhang, H; Zhang, X; Zhou, J | 1 |
| Chaban, GM; Huo, WM; Wang, D | 1 |
| Kobayashi, J; Suzuki, M; Takao, M; Takatori, K; Yamasaki, A; Yoshikawa, Y; Zhang-Akiyama, QM | 1 |
| Gordhan, BG; Hassim, F; Kana, BD; Papadopoulos, AO | 1 |
| Milhøj, BO; Sauer, SP | 1 |
| Aranda, J; Bellili, A; Dumont, E; Grüber, R; Tuñón, I | 1 |
| Bilotti, K; Delaney, S; Tarantino, ME | 1 |
| Bhattacharjee, K; Shukla, PK | 1 |
| Li, C; Liu, P; Wang, D; Wang, S | 1 |
| Hebert, SP; Schlegel, HB | 1 |
| Kellett, A; McKee, V; Molphy, Z | 1 |
| Tsuchida, N; Yamabe, S; Yamazaki, S | 1 |
| Burrows, CJ; Fleming, AM | 1 |
| Wang, Y; Wei, S | 1 |
3 review(s) available for hydroxyl radical and guanine
| Article | Year |
|---|---|
[DNA oxidative damages--free radical modification of bases and sugar moieties].
Topics: Adenine; Anaerobiosis; Carbohydrate Metabolism; Cytosine; DNA; Free Radicals; Guanine; Hydroxyl Radical; Mutagenesis; Oxidation-Reduction; Purines; Pyrimidines | 1997 |
Magnesium-DNA interactions and the possible relation of magnesium to carcinogenesis. Irradiation and free radicals.
Topics: Animals; Cations, Divalent; DNA; DNA Damage; DNA Repair; Guanine; Guanosine Monophosphate; Humans; Hydrogen Bonding; Hydroxyl Radical; Immunologic Deficiency Syndromes; Magnesium; Magnesium Deficiency; Neoplasms; Nucleic Acid Conformation; Oxidative Stress; Radiation Injuries; Radiation Tolerance; Radiotherapy; Rats; Superoxides; Whole-Body Irradiation | 2002 |
Oxidative damage to DNA: formation, measurement and biochemical features.
Topics: Animals; DNA Adducts; DNA Damage; Guanine; Humans; Hydroxyl Radical; Mutagenesis; Oxidation-Reduction; Oxidative Stress; Oxygen; Radiation Dosage; Reactive Oxygen Species | 2003 |
56 other study(ies) available for hydroxyl radical and guanine
| Article | Year |
|---|---|
Detection of drug binding to DNA by hydroxyl radical footprinting. Relationship of distamycin binding sites to DNA structure and positioned nucleosomes on 5S RNA genes of Xenopus.
Topics: Animals; Base Composition; Base Sequence; Binding Sites; Cytosine; Dactinomycin; Distamycins; DNA; Edetic Acid; Guanine; Hydroxides; Hydroxyl Radical; Kinetics; Methods; Molecular Sequence Data; Nucleic Acid Conformation; Nucleosomes; RNA, Ribosomal; RNA, Ribosomal, 5S; Xenopus | 1990 |
Bleomycin-iron damage to DNA with formation of 8-hydroxydeoxyguanosine and base propenals. Indications that xanthine oxidase generates superoxide from DNA degradation products.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Bleomycin; Cattle; Deoxyguanosine; DNA; DNA Damage; Electron Spin Resonance Spectroscopy; Free Radicals; Guanine; Hydroxides; Hydroxyl Radical; Iron; Superoxides; Thiobarbiturates; Xanthine Oxidase | 1990 |
Hydroxyl free radical mediated formation of 8-hydroxyguanine in isolated DNA.
Topics: Animals; Cattle; DNA; DNA Damage; Guanine; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Thiourea; Ultraviolet Rays | 1988 |
DNA damage in human respiratory tract epithelial cells: damage by gas phase cigarette smoke apparently involves attack by reactive nitrogen species in addition to oxygen radicals.
Topics: Adenine; Bronchi; Cell Line; DNA; DNA Damage; Epithelium; Guanine; Humans; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; Smoke; Smoking; Xanthine; Xanthines | 1995 |
The influence of the 2-amino group of guanine on DNA conformation. Uranyl and DNase I probing of inosine/diaminopurine substituted DNA.
Topics: Base Sequence; Binding Sites; Deoxyribonuclease I; DNA Primers; DNA, Bacterial; Escherichia coli; Guanine; Hydroxyl Radical; In Vitro Techniques; Ligands; Molecular Sequence Data; Molecular Structure; Nucleic Acid Conformation; Photochemistry; Polymerase Chain Reaction; Promoter Regions, Genetic; Uranyl Nitrate | 1995 |
Oxidative DNA damage induced by potassium bromate under cell-free conditions and in mammalian cells.
Topics: Animals; Bromates; Bromine; Carcinogens; Cattle; Cell-Free System; Cells, Cultured; DNA Damage; DNA, Viral; Free Radical Scavengers; Free Radicals; Glutathione; Guanine; Hydroxyl Radical; Kidney; Leukemia L1210; Mice; Oxidation-Reduction; Reactive Oxygen Species | 1995 |
Interaction of mithramycin with isolated GC and CG sites.
Topics: Adenine; Base Sequence; Binding Sites; Carbohydrate Sequence; Cytosine; Deoxyribonuclease I; DNA; Electrophoresis, Polyacrylamide Gel; Guanine; Hydroxyl Radical; Molecular Sequence Data; Molecular Structure; Plicamycin; Thymine | 1994 |
Reaction of Cr(VI) with ascorbate and hydrogen peroxide generates hydroxyl radicals and causes DNA damage: role of a Cr(IV)-mediated Fenton-like reaction.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Ascorbic Acid; Chromium; DNA; DNA Damage; Guanine; Hydrogen Peroxide; Hydroxyl Radical; Hydroxylation | 1994 |
Methylene blue and rose bengal photoinactivation of RNA bacteriophages: comparative studies of 8-oxoguanine formation in isolated RNA.
Topics: Centrifugation, Density Gradient; Guanine; Hydroxides; Hydroxyl Radical; Iron Chelating Agents; Light; Methylene Blue; Oxygen; Photochemistry; RNA Phages; RNA, Viral; Rose Bengal; Singlet Oxygen; Temperature | 1993 |
Adjacent guanines as preferred sites for strand breaks in plasmid DNA irradiated with 193 nm and 248 nm UV laser light.
Topics: Base Sequence; DNA Damage; DNA, Single-Stranded; Guanine; Hydroxyl Radical; Lasers; Molecular Sequence Data; Nucleic Acid Conformation; Photolysis; Plasmids; Restriction Mapping; Ultraviolet Rays | 1996 |
Inhibitory effect of ethyl oleate hydroperoxide and alcohol in photosensitized oxidative DNA damage.
Topics: Animals; Cattle; Deoxyguanosine; DNA Damage; Guanine; Hydroxyl Radical; Molecular Structure; Oleic Acids; Oxidation-Reduction; Peroxides; Photosensitizing Agents; Xanthenes; Xanthones | 1996 |
Oxidative DNA damage in the parkinsonian brain: an apparent selective increase in 8-hydroxyguanine levels in substantia nigra.
Topics: Aged; Aged, 80 and over; Aging; Base Composition; DNA; DNA Damage; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Hydroxyl Radical; Middle Aged; Nitrates; Oxidants; Oxidation-Reduction; Parkinson Disease; Pyrimidines; Reference Values; Regression Analysis; Substantia Nigra | 1997 |
Hydroxyl radicals are involved in the oxidation of isolated and cellular DNA bases by 5-aminolevulinic acid.
Topics: Aminolevulinic Acid; Animals; Base Composition; Cattle; Cytosine; DNA; Guanine; Hydroxyl Radical; Male; Oxidation-Reduction; Rats; Rats, Wistar | 1998 |
Synthesis of creatol, a hydroxyl radical adduct of creatinine and its increase by puromycin aminonucleoside in isolated rat hepatocytes.
Topics: Animals; Cells, Cultured; Creatinine; Dimethyl Sulfoxide; Guanine; Hydroxyl Radical; Liver; Male; Puromycin Aminonucleoside; Rats; Rats, Wistar | 1998 |
Protection against radiation-induced degradation of DNA bases by polyamines.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Amidines; Cytosine; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Dimethyl Sulfoxide; DNA; DNA Damage; Dose-Response Relationship, Drug; Gamma Rays; Gas Chromatography-Mass Spectrometry; Guanine; Hydroxyl Radical; Oxidation-Reduction; Polyamines; Purines; Putrescine; Pyrimidines; Radiation-Protective Agents; Solutions; Spermidine; Spermine | 2000 |
5'-nicked apurinic/apyrimidinic sites are resistant to beta-elimination by beta-polymerase and are persistent in human cultured cells after oxidative stress.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Cattle; Deoxyribonuclease (Pyrimidine Dimer); DNA; DNA Damage; DNA Polymerase beta; DNA Repair; Dose-Response Relationship, Drug; Endodeoxyribonucleases; Escherichia coli; Escherichia coli Proteins; Guanine; HeLa Cells; Humans; Hydrogen Peroxide; Hydroxyl Radical; Oxidative Stress; Rats; Reactive Oxygen Species; Thymus Gland; Time Factors | 2000 |
Reaction of HO* with guanine derivatives in aqueous solution: formation of two different redox-active OH-adduct radicals and their unimolecular transformation reactions. Properties of G(-H)*.
Topics: Deoxyguanosine; DNA; Guanine; Hydrogen-Ion Concentration; Hydroxyl Radical; Models, Chemical; Oxidation-Reduction; Solutions; Spectrophotometry, Atomic | 2000 |
Activated leukocytes oxidatively damage DNA, RNA, and the nucleotide pool through halide-dependent formation of hydroxyl radical.
Topics: Animals; Bromates; DNA Damage; Eosinophils; Guanine; Halogens; Humans; Hydroxyl Radical; Hypochlorous Acid; Leukocytes; Liver; Mutagens; Neutrophils; Nucleotides; Oxidative Stress; Peroxidases; Reactive Oxygen Species; RNA | 2000 |
DNA degradation by the mixture of copper and catechol is caused by DNA-copper-hydroperoxo complexes, probably DNA-Cu(I)OOH.
Topics: Catechols; Copper; DNA; DNA Damage; Free Radical Scavengers; Guanine; Hydroxyl Radical; Osmolar Concentration; Piperidines; Reactive Oxygen Species | 2000 |
Single 8-oxo-guanine and 8-oxo-adenine lesions induce marked changes in the backbone structure of a 25-base DNA strand.
Topics: Adenine; DNA; DNA Damage; Guanine; Hydroxyl Radical; Multivariate Analysis; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Spectroscopy, Fourier Transform Infrared | 2000 |
Redox reactivity of guanyl radicals in plasmid DNA.
Topics: Bromides; DNA Damage; DNA-Formamidopyrimidine Glycosylase; DNA, Bacterial; DNA, Superhelical; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Free Radical Scavengers; Free Radicals; Gamma Rays; Guanine; Hydroxyl Radical; Iodides; N-Glycosyl Hydrolases; Oxidation-Reduction; Plasmids; Thiocyanates | 2001 |
Ntg2 of Saccharomyces cerevisiae repairs the oxidation products of 8-hydroxyguanine.
Topics: Borohydrides; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; DNA; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA-Formamidopyrimidine Glycosylase; Dose-Response Relationship, Radiation; Escherichia coli Proteins; Gamma Rays; Guanine; Hydrogen Peroxide; Hydroxyl Radical; Iron; Macromolecular Substances; N-Glycosyl Hydrolases; Oxidation-Reduction; Piperidines; Protein Binding; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Substrate Specificity; Thymidine | 2001 |
Age-related radical-induced DNA damage is linked to prostate cancer.
Topics: Adenine; Age Factors; Cell Transformation, Neoplastic; DNA; DNA Damage; DNA, Neoplasm; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Hydroxyl Radical; Logistic Models; Male; Middle Aged; Models, Biological; Prostate; Prostatic Neoplasms; Pyrimidines | 2001 |
DNA-protein cross-linking via guanine oxidation: dependence upon protein and photosensitizer.
Topics: Animals; Base Sequence; Cattle; Cross-Linking Reagents; Cytochrome c Group; DNA; DNA Damage; Electrochemistry; Electrophoresis, Polyacrylamide Gel; Guanine; Heme; Histones; Horses; Hydroxyl Radical; Molecular Sequence Data; Oxidation-Reduction; Photochemistry; Photosensitizing Agents; Piperidines; Serum Albumin, Bovine | 2003 |
Mechanism of RNA 2'-O-methylation: evidence that the catalytic lysine acts to steer rather than deprotonate the target nucleophile.
Topics: Carbon Isotopes; Catalytic Domain; Guanine; Hydrogen-Ion Concentration; Hydroxides; Hydroxyl Radical; Lysine; Methyltransferases; Nuclear Magnetic Resonance, Biomolecular; Osmolar Concentration; Protons; RNA Caps; RNA, Viral; Substrate Specificity; Vaccinia virus; Viral Proteins | 2004 |
Mechanisms of formation of 8-oxoguanine due to reactions of one and two OH* radicals and the H2O2 molecule with guanine: A quantum computational study.
Topics: Binding, Competitive; Computer Simulation; Guanine; Hydrogen Peroxide; Hydroxyl Radical; Models, Chemical; Models, Molecular; Molecular Structure; Quantum Theory; Thermodynamics | 2005 |
Effects of OH radical addition on proton transfer in the guanine-cytosine base pair.
Topics: Base Pairing; Cytosine; Guanine; Hydrogen Bonding; Hydroxyl Radical; Models, Chemical; Molecular Structure; Nucleic Acid Conformation; Protons; Thermodynamics | 2007 |
Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage.
Topics: Animals; Cell Survival; Comet Assay; Diterpenes; DNA Damage; Dose-Response Relationship, Drug; Fibroblasts; Free Radical Scavengers; Guanine; Hydrogen Peroxide; Hydroxyl Radical; Lipid Peroxidation; Mice; NIH 3T3 Cells; Oxidants; Oxidative Stress; Reactive Oxygen Species; Superoxides; Time Factors | 2007 |
Effect of amino acids on X-ray-induced hydrogen peroxide and hydroxyl radical formation in water and 8-oxoguanine in DNA.
Topics: Amino Acids; Antioxidants; DNA; DNA Damage; Free Radical Scavengers; Guanine; Hydrogen Peroxide; Hydroxyl Radical; Water; X-Rays | 2008 |
Formation of cross-linked adducts between guanine and thymine mediated by hydroxyl radical and one-electron oxidation: a theoretical study.
Topics: Electrons; Gases; Guanine; Hydroxyl Radical; Kinetics; Models, Molecular; Molecular Structure; Oxidation-Reduction; Thermodynamics; Thymine | 2008 |
A reevaluation of the ambident reactivity of the guanine moiety towards hydroxyl radicals.
Topics: Deoxyguanosine; Guanine; Hydroxyl Radical | 2009 |
Optical control of DNA base radio sensitivity.
Topics: Diffusion; DNA; DNA Damage; Electrons; Guanine; Hydroxyl Radical; Light; Magnetics; Models, Molecular; Molecular Conformation; Optical Phenomena; Oxygen; Quantum Theory; Radio Waves; Solutions; Thermodynamics; Time Factors | 2009 |
Peculiarities of the antioxidant and radioprotective effects of hydrated C60 fullerene nanostuctures in vitro and in vivo.
Topics: Animals; Antioxidants; Apoptosis; Cell Line; Coumarins; DNA Damage; Free Radical Scavengers; Fullerenes; Guanine; Hydroxyl Radical; Injections, Intraperitoneal; Intestinal Mucosa; Male; Mice; Nanostructures; Nanotechnology; Oxidation-Reduction; Oxidative Stress; Radiation Injuries, Experimental; Radiation-Protective Agents; Radiation, Ionizing; Rats; Water; Weight Gain | 2009 |
Influence of percentage of guanine molecules, OH radicals, UV irradiation and temperature on electrooxidation of short synthetic oligonucleotides.
Topics: Circular Dichroism; Electrochemical Techniques; Guanine; Hydroxyl Radical; Oligonucleotides; Oxidation-Reduction; Spectrophotometry, Ultraviolet; Temperature; Ultraviolet Rays | 2011 |
Oxidatively generated damage to DNA by UVA radiation in cells and human skin.
Topics: Cells, Cultured; DNA Breaks, Double-Stranded; DNA Damage; Guanine; Humans; Hydroxyl Radical; Oxidative Stress; Singlet Oxygen; Skin; Ultraviolet Rays | 2011 |
Spectral characterization of guanine C4-OH adduct: a radiation and quantum chemical study.
Topics: Guanine; Hydrogen-Ion Concentration; Hydroxyl Radical; Quantum Theory; Superoxides | 2011 |
Hydroxyl radical (OH•) reaction with guanine in an aqueous environment: a DFT study.
Topics: Guanine; Hydrogen; Hydroxyl Radical; Kinetics; Models, Molecular; Molecular Conformation; Quantum Theory; Water | 2011 |
Multiscale QM/MM molecular dynamics study on the first steps of guanine damage by free hydroxyl radicals in solution.
Topics: DNA; Guanine; Hydroxyl Radical; Molecular Dynamics Simulation; Solutions | 2012 |
Oxidation of the guanine nucleotide pool underlies cell death by bactericidal antibiotics.
Topics: Ampicillin; Anti-Bacterial Agents; Deoxyguanine Nucleotides; DNA Breaks, Double-Stranded; DNA Glycosylases; DNA Polymerase beta; DNA Polymerase I; DNA Polymerase II; DNA-Directed DNA Polymerase; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Guanine; Guanine Nucleotides; Hydroxyl Radical; Kanamycin; Microbial Viability; Models, Biological; Norfloxacin; Oxidation-Reduction; Pyrophosphatases; RNA, Bacterial | 2012 |
Proton-coupled hole hopping in nucleosomal and free DNA initiated by site-specific hole injection.
Topics: 2-Aminopurine; Base Sequence; DNA; DNA Damage; Guanine; Histones; Hydroxyl Radical; Models, Molecular; Molecular Sequence Data; Nucleosomes; Oxidation-Reduction; Protein Multimerization; Protein Refolding; Protons; Recombinant Proteins | 2012 |
Electrochemical antioxidant detection technique based on guanine-bonded graphene and magnetic nanoparticles composite materials.
Topics: Antioxidants; Biosensing Techniques; Electrochemical Techniques; Ferric Compounds; Graphite; Guanine; Humans; Hydrogen Peroxide; Hydroxyl Radical; Magnetic Fields; Metal Nanoparticles; Oxidation-Reduction; Oxygen | 2012 |
Pro-oxidative, genotoxic and cytotoxic properties of uranyl ions.
Topics: Animals; Blood Proteins; Bone Marrow; DNA Damage; Guanine; Hot Temperature; Hydrogen Peroxide; Hydroxyl Radical; Ions; Lasers; Male; Mice; Mortality; Mutagenicity Tests; Reactive Oxygen Species; Uranium; Uranyl Nitrate; X-Rays | 2014 |
Electrochemical evaluation of total antioxidant capacities in fruit juice based on the guanine/graphene nanoribbon/glassy carbon electrode.
Topics: Antioxidants; Ascorbic Acid; Beverages; Biosensing Techniques; Electrochemical Techniques; Electrodes; Fruit; Graphite; Guanine; Humans; Hydroxyl Radical; Limit of Detection; Nanotubes, Carbon; Reference Standards; Reproducibility of Results | 2013 |
Ab initio study of guanine damage by hydroxyl radical.
Topics: Guanine; Hydrogen; Hydroxyl Radical; Molecular Structure; Water | 2015 |
Excess processing of oxidative damaged bases causes hypersensitivity to oxidative stress and low dose rate irradiation.
Topics: Biomarkers; DNA Breaks, Double-Stranded; DNA Damage; DNA Glycosylases; DNA Repair; Enzyme Induction; Gamma Rays; Guanine; Heavy Ions; HeLa Cells; Histones; Humans; Hydrogen Peroxide; Hydroxyl Radical; Micronucleus Tests; Oxidative Stress; Radiation Tolerance; Recombinant Fusion Proteins; Transfection; Ultraviolet Rays | 2015 |
A combinatorial role for MutY and Fpg DNA glycosylases in mutation avoidance in Mycobacterium smegmatis.
Topics: DNA Glycosylases; DNA Repair; DNA-Formamidopyrimidine Glycosylase; Genome, Bacterial; Guanine; Hydroxyl Radical; Mutagenesis; Mutagens; Mutation; Mycobacterium smegmatis; Oxidative Stress; Pyrimidines | 2015 |
Insight into the Mechanism of the Initial Reaction of an OH Radical with DNA/RNA Nucleobases: A Computational Investigation of Radiation Damage.
Topics: Adenine; Computer Simulation; DNA; Guanine; Hydroxyl Radical; Kinetics; RNA; Thymine; Uracil | 2015 |
Free energy profiles for two ubiquitous damaging agents: methylation and hydroxylation of guanine in B-DNA.
Topics: DNA Methylation; DNA, B-Form; Energy Transfer; Entropy; Guanine; Hydroxyl Radical; Hydroxylation | 2017 |
Human Oxoguanine Glycosylase 1 Removes Solution Accessible 8-Oxo-7,8-dihydroguanine Lesions from Globally Substituted Nucleosomes Except in the Dyad Region.
Topics: DNA; DNA Glycosylases; DNA Repair; Guanine; Humans; Hydroxyl Radical; Models, Molecular; Nucleosomes; Structure-Activity Relationship | 2018 |
Does 8-Nitroguanine Form 8-Oxoguanine? An Insight from Its Reaction with
Topics: Guanine; Hydroxyl Radical; Quantum Theory | 2018 |
Catalytic Effect of Aqueous Solution in Water-Assisted Proton-Transfer Mechanism of 8-Hydroxy Guanine Radical.
Topics: Catalysis; Guanine; Hydroxyl Radical; Protons; Quantum Theory; Solutions; Thermodynamics; Water | 2018 |
Computational Study of the Oxidation of Guanine To Form 5-Carboxyamido-5-formamido-2-iminohydantoin (2Ih).
Topics: Guanine; Hydantoins; Hydroxyl Radical; Oxidation-Reduction | 2019 |
Copper
Topics: Copper; Crystallography, X-Ray; Cytosine; Deoxyribonucleases; DNA; DNA Cleavage; DNA Damage; Guanine; Hydroxyl Radical; Intercalating Agents; Organometallic Compounds; Oxidation-Reduction; Quinoxalines; Superoxides | 2019 |
DFT Study of the Hydroxyl Radical Addition to 2'-Deoxyguanosine and the Guanine Base in Four Double-Stranded B-Form Dimers.
Topics: Density Functional Theory; Deoxyguanosine; Dimerization; Guanine; Hydroxyl Radical | 2020 |
Chemistry of ROS-mediated oxidation to the guanine base in DNA and its biological consequences.
Topics: DNA; DNA Damage; DNA Repair; Guanine; Hydroxyl Radical; Oxidation-Reduction; Reactive Oxygen Species | 2022 |
Theoretical insights into the reaction mechanism of hydroxyl radicals and guanine in G-quadruplex DNA.
Topics: Free Radicals; G-Quadruplexes; Guanine; Hydrogen; Hydrogen Bonding; Hydroxyl Radical | 2023 |