hydroxyl radical has been researched along with glutamic acid in 51 studies
| Studies (hydroxyl radical) | Trials (hydroxyl radical) | Recent Studies (post-2010) (hydroxyl radical) | Studies (glutamic acid) | Trials (glutamic acid) | Recent Studies (post-2010) (glutamic acid) |
|---|---|---|---|---|---|
| 10,147 | 26 | 3,657 | 41,757 | 452 | 12,876 |
| Protein | Taxonomy | hydroxyl radical (IC50) | glutamic acid (IC50) |
|---|---|---|---|
| Chain A, GLUTAMATE RECEPTOR SUBUNIT 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Chain A, Glutamate Receptor Subunit 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Chain B, Glutamate Receptor Subunit 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Metabotropic glutamate receptor 8 | Homo sapiens (human) | 0.0057 | |
| Glutamate receptor ionotropic, NMDA 2D | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 3B | Homo sapiens (human) | 0.07 | |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor 1 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor 2 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor 3 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | 0.38 | |
| Excitatory amino acid transporter 1 | Homo sapiens (human) | 207 | |
| Glutamate receptor 4 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2C | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 3A | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 0.1533 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (3.92) | 18.7374 |
| 1990's | 19 (37.25) | 18.2507 |
| 2000's | 19 (37.25) | 29.6817 |
| 2010's | 11 (21.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Calinon, F; Delbarre, B; Delbarre, G; Floyd, RA | 1 |
| Alesiani, M; Carlà, V; Cherici, G; Moroni, F; Pellegrini-Giampietro, DE | 1 |
| Berteloot, A | 1 |
| Alonso, O; Busto, R; Dietrich, WD; Ginsberg, MD; Globus, MY | 1 |
| Kuo, JS; Lin, NN; Liu, L; Tsai, PJ; Yang, CS | 2 |
| Boulu, RG; Callebert, J; Lancelot, E; Plotkine, M | 1 |
| Calinon, F; Delbarre, B; Delbarre, G | 1 |
| Gohda, K; Hakoshima, T; Oka, K; Tomita, K | 1 |
| Hiramatsu, M; Komatsu, M; Ueda, Y | 1 |
| Folz, RJ; Levin, ED; Piantadosi, CA; Schmechel, DE; Zhang, J | 1 |
| Ferger, B; Kuschinsky, K; Seyfried, C; van Amsterdam, C | 1 |
| Boulu, RG; Callebert, J; Lancelot, E; Lecanu, L; Plotkine, M; Revaud, ML | 1 |
| Quast, MJ; Wei, J | 1 |
| Ishikawa, T; Kawai, S; Marsala, M; Sakabe, T; Taguchi, T; Yamamoto, K | 1 |
| Boulu, RG; Callebert, J; Lancelot, E; Plotkine, M; Revaud, ML | 1 |
| Bringmann, G; Feineis, D; Gerlach, M; God, R; Heim, C; Lan, J; Riederer, P; Sontag, KH; Xiao, AY | 1 |
| Huguet, F; Piriou, A; Pontcharraud, R; Remblier, C; Tallineau, C | 1 |
| Glowinski, J; Israël, M; Mailly, F; Marin, P; Prémont, J | 1 |
| Barbanel, G; Cauquil-Caubère, I; Kamenka, JM; Oxhamre, C | 1 |
| Cheng, FC; Dryhurst, G; Han, J; Yang, Z | 1 |
| Ferger, B; Teismann, P | 2 |
| Gerlach, M; Heim, C; Kurz, T; Lan, J; Riederer, P; Sieklucka, M; Sontag, KH; Zhang, J | 1 |
| Li, Y; Wavak, D; Wolf, ME; Xue, CJ | 1 |
| Barbanel, G; Cambonie, G; Kamenka, JM; Laplanche, L | 1 |
| Barbanel, G; Cambonie, G; Kamenka, JM | 1 |
| Barbanel, G; Kamenka, JM; Laplanche, L; Michaud, M | 1 |
| Feldon, J; Ferger, B; Leng, A | 1 |
| Barbanel, G; Cambonie, G; Hirbec, H; Kamenka, JM; Michaud, M | 1 |
| Hirooka, Y; Ito, K; Kimura, Y; Kishi, T; Shimokawa, H; Takeshita, A | 1 |
| Endo, T; Hara, S; Kuriiwa, F; Kurosaki, K; Mukai, T | 1 |
| Huang, WT; Liao, JF; Lin, MT; Tsai, CC; Wang, JJ | 1 |
| Anderzhanova, E; Oja, SS; Saransaari, P | 1 |
| Chang, CP; Huang, WT; Kao, TY; Lin, MT | 1 |
| Huang, WT; Kao, CH; Kao, TY; Lin, MT | 1 |
| Dennis, DM; Glushakov, AV; Gravenstein, N; Martynyuk, AE; Seubert, CN; Sumners, C; Yarotskyy, V | 1 |
| McAdoo, DJ; Wu, P | 1 |
| Chang, CK; Chang, CP; Huang, WT; Lin, MT; Niu, KC | 1 |
| Huang, KF; Huang, WT; Lin, MT; Niu, KC | 1 |
| Chang, CP; Huang, KF; Huang, WT; Lin, KC; Lin, MT | 1 |
| Quan, JM; Wu, XH; Wu, YD; Zou, GL | 1 |
| Huang, WT; Kao, CH; Lin, MT; Wu, WS | 1 |
| Dziubina, A; Gołembiowska, K | 2 |
| Górska, A; Gołembiowska, K; Kamińska, K; Noworyta-Sokołowska, K; Wardas, J | 1 |
| Chang, CH; Chen, SH; Huang, WT; Kao, CH; Lin, CH | 1 |
| Ahn, MJ; Bae, JM; Bae, JY; Jang, I; Kang, SN; Kim, IS; Kwak, SS; Lee, CH; Lee, HS; Lee, SW; Yoon, KD | 1 |
| Górska, A; Gołembiowska, K; Noworyta-Sokołowska, K | 1 |
| Cui, H; Danish, M; Farooq, U; Fu, X; Gu, X; Lu, S; Miao, Z; Qiu, Z; Sui, Q; Xu, M; Zhang, X | 1 |
| Keshavarz, F; Mazarei, E | 1 |
2 review(s) available for hydroxyl radical and glutamic acid
| Article | Year |
|---|---|
Halogenated derivatives of aromatic amino acids exhibit balanced antiglutamatergic actions: potential applications for the treatment of neurological and neuropsychiatric disorders.
Topics: Animals; Brain; Brain Diseases; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Hydroxyl Radical; Mental Disorders; Neuroprotective Agents; Phenylalanine; Synaptic Transmission; Tyrosine | 2006 |
Microdialysis in central nervous system disorders and their treatment.
Topics: Animals; Brain Injuries; Calibration; Central Nervous System Diseases; Glutamic Acid; Hydroxyl Radical; Microdialysis; Neurons; Pain; Reactive Oxygen Species; Spinal Cord Injuries; Zinc | 2008 |
49 other study(ies) available for hydroxyl radical and glutamic acid
| Article | Year |
|---|---|
Glutamate accumulation and increased hydroxyl free radical formation in the abdominal aorta and heart of gerbil after ischemia/reperfusion insult.
Topics: Animals; Aorta, Abdominal; Female; Free Radicals; Gentisates; Gerbillinae; Glutamates; Glutamic Acid; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Male; Myocardium; Reperfusion Injury | 1992 |
Excitatory amino acid release from rat hippocampal slices as a consequence of free-radical formation.
Topics: Allopurinol; Amino Acids; Animals; Aspartic Acid; Catalase; Free Radicals; Glutamates; Glutamic Acid; Hippocampus; Hydroxides; Hydroxyl Radical; Male; Mannitol; Norepinephrine; Rats; Rats, Inbred Strains; Superoxide Dismutase; Superoxides; Xanthine; Xanthine Oxidase; Xanthines | 1988 |
Characteristics of glutamic acid transport by rabbit intestinal brush-border membrane vesicles. Effects of Na+-, K+- and H+-gradients.
Topics: Animals; Glutamates; Glutamic Acid; Hydrogen; Hydrogen-Ion Concentration; Hydroxides; Hydroxyl Radical; Intestines; Male; Mice; Microvilli; Osmolar Concentration; Potassium; Rabbits; Sodium | 1984 |
Glutamate release and free radical production following brain injury: effects of posttraumatic hypothermia.
Topics: Animals; Brain Injuries; Free Radicals; Gentisates; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Hypothermia; Male; Microdialysis; Rats; Rats, Sprague-Dawley | 1995 |
Elevated extracellular glutamate levels increased the formation of hydroxyl radical in the striatum of anesthetized rat.
Topics: Anesthesia; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Extracellular Space; Gentisates; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Kinetics; Male; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid | 1995 |
Striatal dopamine participates in glutamate-induced hydroxyl radical generation.
Topics: Animals; Clorgyline; Dopamine; Glutamic Acid; Hydroxyl Radical; Male; Microdialysis; Neostriatum; Rats; Rats, Sprague-Dawley; Salicylates; Selegiline | 1995 |
Action of trimetazidine on retina of gerbils after ischemia reperfusion insult: determination of .OH, amino acids, and electroretinogram.
Topics: Amino Acids; Animals; Aspartic Acid; Electroretinography; Female; gamma-Aminobutyric Acid; Gentisates; Gerbillinae; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Ischemia; Male; Reperfusion Injury; Retina; Retinal Vessels; Trimetazidine | 1994 |
Crystal structure of RNase T1 complexed with the product nucleotide 3'-GMP. Structural evidence for direct interaction of histidine 40 and glutamic acid 58 with the 2'-hydroxyl group of the ribose.
Topics: Binding Sites; Crystallography, X-Ray; Glutamates; Glutamic Acid; Guanosine Monophosphate; Histidine; Hydrogen Bonding; Hydroxyl Radical; Isomerism; Models, Molecular; Molecular Sequence Data; Protein Conformation; Ribonuclease T1 | 1994 |
In vivo evidence of hydroxyl radical formation induced by elevation of extracellular glutamate after cerebral ischemia in the cortex of anesthetized rats.
Topics: Animals; Brain Ischemia; Cerebral Cortex; Chromatography, High Pressure Liquid; Glutamic Acid; Hydroxyl Radical; Hydroxylation; Kinetics; Male; Microdialysis; Oxidative Stress; Perfusion; Rats; Rats, Sprague-Dawley; Time Factors | 1996 |
Free radical scavenging activity of the Japanese herbal medicine toki-shakuyaku-san (TJ-23) and its effect on superoxide dismutase activity, lipid peroxides, glutamate, and monoamine metabolites in aged rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amino Acids; Animals; Bepridil; Biogenic Monoamines; Biphenyl Compounds; Brain; Dopamine; Drugs, Chinese Herbal; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Glutamic Acid; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Hydroxyl Radical; Lipid Peroxides; Methoxyhydroxyphenylglycol; Mice; Neurotransmitter Agents; Norepinephrine; Organ Specificity; Picrates; Plants, Medicinal; Rats; Serotonin; Superoxide Dismutase; Superoxides; Thiobarbituric Acid Reactive Substances | 1996 |
Apoptosis and delayed neuronal damage after carbon monoxide poisoning in the rat.
Topics: Animals; Apoptosis; Behavior, Animal; Brain; Carbon Monoxide Poisoning; DNA Fragmentation; Glutamic Acid; Hydroxyl Radical; Hydroxylation; Male; Microdialysis; Microscopy, Electron; Neurons; Rats; Rats, Sprague-Dawley; Time Factors | 1997 |
Effects of alpha-phenyl-tert-butylnitrone and selegiline on hydroxyl free radicals in rat striatum produced by local application of glutamate.
Topics: Administration, Topical; Animals; Corpus Striatum; Cyclic N-Oxides; Free Radical Scavengers; Gentisates; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Monoamine Oxidase Inhibitors; Nitrogen Oxides; Rats; Rats, Wistar; Selegiline | 1998 |
Glutamate induces hydroxyl radical formation in vivo via activation of nitric oxide synthase in Sprague-Dawley rats.
Topics: Animals; Corpus Striatum; Enzyme Inhibitors; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid | 1998 |
Effect of nitric oxide synthase inhibitor on a hyperglycemic rat model of reversible focal ischemia: detection of excitatory amino acids release and hydroxyl radical formation.
Topics: Animals; Cell Survival; Citrulline; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Inhibitors; Glutamic Acid; Hydroxyl Radical; Hyperglycemia; Ischemic Attack, Transient; Magnetic Resonance Imaging; Male; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 1998 |
The hydroxyl radical scavenger Nicaraven inhibits glutamate release after spinal injury in rats.
Topics: Animals; Free Radical Scavengers; Glutamic Acid; Hydroxyl Radical; Hypothermia, Induced; Male; Niacinamide; Rats; Rats, Sprague-Dawley; Reference Values; Spinal Cord; Spinal Cord Injuries; Time Factors | 1998 |
A microdialysis study investigating the mechanisms of hydroxyl radical formation in rat striatum exposed to glutamate.
Topics: 2-Amino-5-phosphonovalerate; Animals; Corpus Striatum; Cyclic N-Oxides; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Iron Chelating Agents; Microdialysis; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitrogen Oxides; Quinacrine; Rats; Rats, Sprague-Dawley | 1998 |
1-Trichloromethyl-1,2,3,4-tetrahydro-beta-carboline increases extracellular serotonin and stimulates hydroxyl radical production in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aspartic Acid; Carbolines; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Homovanillic Acid; Hydroxybenzoates; Hydroxyindoleacetic Acid; Hydroxyl Radical; Male; Microdialysis; Rats; Rats, Wistar; Serotonin | 1998 |
Lactic acid-induced increase of extracellular dopamine measured by microdialysis in rat striatum: evidence for glutamatergic and oxidative mechanisms.
Topics: Acidosis, Lactic; Animals; Antioxidants; Chromans; Chromatography, High Pressure Liquid; Corpus Striatum; Dizocilpine Maleate; Dopamine; Electrochemistry; Gentisates; Glutamic Acid; Hydrogen-Ion Concentration; Hydroxybenzoates; Hydroxyl Radical; Kinetics; Lactic Acid; Male; Microdialysis; Rats; Rats, Sprague-Dawley | 1999 |
Increase in external glutamate and NMDA receptor activation contribute to H2O2-induced neuronal apoptosis.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Cell Survival; Cells, Cultured; Cerebral Cortex; Extracellular Space; Glutamic Acid; Hydrogen Peroxide; Hydroxyl Radical; Mice; NAD; Neurons; Oxidants; Poly(ADP-ribose) Polymerases; Receptors, N-Methyl-D-Aspartate | 1999 |
Recurrent glutamate stimulations potentiate the hydroxyl radicals response to glutamate.
Topics: Animals; Corpus Striatum; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Rats | 1999 |
Inhibitors of mitochondrial respiration, iron (II), and hydroxyl radical evoke release and extracellular hydrolysis of glutathione in rat striatum and substantia nigra: potential implications to Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Corpus Striatum; Cysteine; Glutamic Acid; Glutathione; Glycine; Hydrolysis; Hydroxyl Radical; Iron; Kinetics; Male; Microdialysis; Mitochondria; Models, Chemical; Nitro Compounds; Oxygen Consumption; Parkinson Disease; Perfusion; Propionates; Rats; Rats, Sprague-Dawley; Substantia Nigra | 1999 |
Comparison of the novel drug Ensaculin with MK-801 on the reduction of hydroxyl radical production in rat striatum after local application of glutamate.
Topics: Animals; Benzopyrans; Corpus Striatum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Gentisates; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; In Vitro Techniques; Male; Microdialysis; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2000 |
Cerebral oligaemia episode triggers free radical formation and late cognitive deficiencies.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aspartic Acid; Carotid Stenosis; Cognition Disorders; Corpus Striatum; Disease Models, Animal; Dopamine; Escape Reaction; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Homovanillic Acid; Hydroxybenzoates; Hydroxyl Radical; Ischemic Attack, Transient; Learning Disabilities; Male; Maze Learning; Memory Disorders; Microdialysis; Oxidative Stress; Psychomotor Performance; Rats; Rats, Wistar; Reaction Time; Reperfusion Injury; Spatial Behavior; Swimming; Time Factors | 2000 |
The salicylate hydroxylation assay to measure hydroxyl free radicals induced by local application of glutamate in vivo or induced by the Fenton reaction in vitro.
Topics: Animals; Dose-Response Relationship, Drug; Gentisates; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Male; Methods; Microdialysis; Rats; Rats, Wistar; Salicylates | 2000 |
Amphetamine increases glutamate efflux in the rat ventral tegmental area by a mechanism involving glutamate transporters and reactive oxygen species.
Topics: Amino Acid Transport System X-AG; Amphetamine; Animals; ATP-Binding Cassette Transporters; Behavior, Animal; Calcium; Central Nervous System Stimulants; Cyclic N-Oxides; Free Radical Scavengers; Glutamic Acid; Hydroxyl Radical; Male; Microdialysis; Motor Activity; Neuroprotective Agents; Nitrogen Oxides; Phenylalanine; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tyrosine; Ventral Tegmental Area | 2000 |
N-methyl-D-aspartate but not glutamate induces the release of hydroxyl radicals in the neonatal rat: modulation by group I metabotropic glutamate receptors.
Topics: Animals; Animals, Newborn; Corpus Striatum; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hydroxybenzoates; Hydroxyl Radical; Hypoxia-Ischemia, Brain; Ibotenic Acid; Indans; Microdialysis; N-Methylaspartate; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols | 2000 |
Glutamate inhibition of NMDA-induced hydroxyl radical release: an ontogenic study in rat.
Topics: Aging; Animals; Animals, Newborn; Brain; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hydroxyl Radical; Microdialysis; N-Methylaspartate; Neurons; Neurotoxins; Oxidative Stress; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Salicylates | 2001 |
Hydroxyl radicals release in rat striatum involves metabotropic glutamate receptors.
Topics: Analysis of Variance; Animals; Corpus Striatum; Cycloleucine; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hydroxyl Radical; Male; Methoxyhydroxyphenylglycol; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Time Factors | 2003 |
Rotenone increases glutamate-induced dopamine release but does not affect hydroxyl-free radical formation in rat striatum.
Topics: Amphetamine; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Densitometry; Dopamine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Electron Transport Complex I; Glutamic Acid; Hydroxyl Radical; Hypokinesia; Immunohistochemistry; Lactic Acid; Locomotion; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; Mitochondria; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Rotenone; Substantia Nigra; Tyrosine 3-Monooxygenase; Uncoupling Agents | 2003 |
Prenatal infection obliterates glutamate-related protection against free hydroxyl radicals in neonatal rat brain.
Topics: 2,3-Diketogulonic Acid; Aging; Animals; Animals, Newborn; Brain; Cell Membrane; Chromatography, High Pressure Liquid; Cyclohexanes; Cyclohexenes; Female; Fetal Diseases; Functional Laterality; Glutamic Acid; Hydroxyl Radical; Lipopolysaccharides; Male; Methoxyhydroxyphenylglycol; Neuroprotective Agents; Oxidative Stress; Piperidines; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Subcellular Fractions; Time Factors | 2004 |
Increased reactive oxygen species in rostral ventrolateral medulla contribute to neural mechanisms of hypertension in stroke-prone spontaneously hypertensive rats.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Animals; Blood Pressure; Brain Chemistry; Catalase; Cyclic N-Oxides; Deferoxamine; Genetic Predisposition to Disease; Genetic Therapy; Glutamic Acid; Hydrogen Peroxide; Hydroxyl Radical; Hypertension; Lipid Peroxidation; Male; Medulla Oblongata; Norepinephrine; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Recombinant Fusion Proteins; Spin Labels; Stroke; Superoxide Dismutase; Superoxides; Sympathetic Nervous System; Thiobarbituric Acid Reactive Substances; Transduction, Genetic; Vasomotor System | 2004 |
Characterization of hydroxyl radical generation in the striatum of free-moving rats due to carbon monoxide poisoning, as determined by in vivo microdialysis.
Topics: Animals; Carbon Monoxide Poisoning; Corpus Striatum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Quinoxalines; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Wakefulness | 2004 |
The antipyretic effects of baicalin in lipopolysaccharide-evoked fever in rabbits.
Topics: Analgesics, Non-Narcotic; Analysis of Variance; Animals; Body Temperature; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Fever; Flavonoids; Glutamic Acid; Hydroxyl Radical; Hypothalamus; Lipopolysaccharides; Male; Microdialysis; Rabbits; Time Factors; Tumor Necrosis Factor-alpha | 2006 |
Neuroprotective mechanisms of taurine in vivo.
Topics: Ammonium Chloride; Amphetamines; Animals; Brain; Brain Chemistry; Central Nervous System Stimulants; Dopamine; Glutamic Acid; Glycine; Hydroxyl Radical; Male; Microdialysis; N-Methylaspartate; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Sydnones; Taurine | 2006 |
Aspirin may exert its antipyresis by inhibiting the N-methyl-D-aspartate receptor-dependent hydroxyl radical pathways in the hypothalamus.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dinoprostone; Fever; Glutamic Acid; Hydroxyl Radical; Hypothalamus; Lipopolysaccharides; Male; Microdialysis; Rabbits; Receptors, N-Methyl-D-Aspartate; Stereotaxic Techniques | 2007 |
Lipopolysaccharide- and glutamate-induced hypothalamic hydroxyl radical elevation and fever can be suppressed by N-methyl-D-aspartate-receptor antagonists.
Topics: Animals; Dinoprostone; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fever; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Hypothalamus; Injections, Intraventricular; Isoquinolines; Lipopolysaccharides; Male; Rabbits; Random Allocation; Receptors, N-Methyl-D-Aspartate | 2007 |
Curcumin inhibits the increase of glutamate, hydroxyl radicals and PGE2 in the hypothalamus and reduces fever during LPS-induced systemic inflammation in rabbits.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Curcumin; Data Interpretation, Statistical; Dinoprostone; Fever; Glutamic Acid; Hydroxyl Radical; Hypothalamus; Inflammation; Injections, Intraventricular; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Male; Rabbits; Tumor Necrosis Factor-alpha | 2008 |
Hyperbaric oxygen causes both antiinflammation and antipyresis in rabbits.
Topics: Acetylcysteine; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents; Body Temperature; Dinoprostone; Glutamic Acid; Hydroxyl Radical; Hyperbaric Oxygenation; Hypothalamus; Injections; Interleukin-6; Lipopolysaccharides; Male; Oxygen; Rabbits | 2009 |
Interleukin-1 receptor antagonist inhibits the release of glutamate, hydroxyl radicals, and prostaglandin E(2) in the hypothalamus during pyrogen-induced fever in rabbits.
Topics: Animals; Body Temperature; Dinoprostone; Fever; Glutamic Acid; Hydroxyl Radical; Hypothalamus; Injections; Interleukin 1 Receptor Antagonist Protein; Interleukin-1beta; Lipopolysaccharides; Male; Pyrogens; Rabbits; Receptors, Interleukin-1; Time Factors | 2010 |
A theoretical study on the catalytic mechanism of Mus musculus adenosine deaminase.
Topics: Adenosine Deaminase; Animals; Catalysis; Energy Transfer; Glutamic Acid; Histidine; Hydroxyl Radical; Kinetics; Mice; Models, Chemical; Models, Molecular; Protein Conformation; Quantum Theory; Zinc | 2010 |
Central interleukin-10 attenuated lipopolysaccharide-induced changes in core temperature and hypothalamic glutamate, hydroxyl radicals and prostaglandin-E(2).
Topics: Animals; Body Temperature; Catechols; Dinoprostone; Fever; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Hypothalamus; Interleukin-10; Lipopolysaccharides; Male; Microdialysis; Rabbits; Tumor Necrosis Factor-alpha | 2011 |
Effect of adenosine A(2A) receptor antagonists and L-DOPA on hydroxyl radical, glutamate and dopamine in the striatum of 6-OHDA-treated rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine A2 Receptor Antagonists; Animals; Benserazide; Caffeine; Dopamine; Glutamic Acid; Hydroxyl Radical; Levodopa; Male; Microdialysis; Neostriatum; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Receptor, Adenosine A2A; Triazines; Triazoles | 2012 |
The effect of adenosine A(2A) receptor antagonists on hydroxyl radical, dopamine, and glutamate in the striatum of rats with altered function of VMAT2.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine A2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Animals; Caffeine; Corpus Striatum; Dopamine; Dopamine Agents; Extracellular Space; Glutamic Acid; Homovanillic Acid; Hydroxyl Radical; Levodopa; Male; Microdialysis; Oxidative Stress; Rats; Rats, Wistar; Reserpine; Triazines; Triazoles; Vesicular Monoamine Transport Proteins | 2012 |
Effects of adenosine receptor antagonists on the in vivo LPS-induced inflammation model of Parkinson's disease.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Corpus Striatum; Dopamine; Dopaminergic Neurons; Glutamic Acid; Hydroxyl Radical; Inflammation; Lipopolysaccharides; Male; Microinjections; Parkinson Disease; Purines; Rats; Receptor, Adenosine A2A | 2013 |
Tetramethylpyrazine decreases hypothalamic glutamate, hydroxyl radicals and prostaglandin-E2 and has antipyretic effects.
Topics: Animals; Antipyretics; Body Temperature; Dinoprostone; Glutamic Acid; Hydroxyl Radical; Hypothalamus; Lipopolysaccharides; Male; Pyrazines; Rabbits; Tumor Necrosis Factor-alpha | 2013 |
Enhanced antioxidant and protective activities on retinal ganglion cells of carotenoids-overexpressing transgenic carrot.
Topics: Acetone; Antioxidants; Biphenyl Compounds; Buthionine Sulfoximine; Carotenoids; Cell Death; Cell Line; Daucus carota; Glutamic Acid; Humans; Hydroxyl Radical; Oxidative Stress; Picrates; Plant Extracts; Plant Roots; Plants, Genetically Modified; Protective Agents; Retinal Ganglion Cells; Superoxides | 2013 |
LPS-induced oxidative stress and inflammatory reaction in the rat striatum.
Topics: Adenosine; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Glutamic Acid; Hydroxyl Radical; Inflammation; Injections, Intraperitoneal; Lipopolysaccharides; Microinjections; Nerve Degeneration; Neuroglia; Oxidative Stress | 2013 |
Enhanced degradation of benzene by percarbonate activated with Fe(II)-glutamate complex.
Topics: Anions; Benzene; Carbonates; Ferric Compounds; Ferrous Compounds; Glutamic Acid; Groundwater; Hydroxyl Radical; Oxidation-Reduction; Superoxides; Water Pollutants, Chemical; Water Purification | 2016 |
From Kinetics of OH Reaction with Glutamic Acid to Oxidative Damage to Proteins.
Topics: Glutamic Acid; Hydroxyl Radical; Kinetics; Models, Chemical; Oxidation-Reduction; Proteins; Quantum Theory | 2019 |