hydroxyl radical has been researched along with etoposide in 4 studies
| Studies (hydroxyl radical) | Trials (hydroxyl radical) | Recent Studies (post-2010) (hydroxyl radical) | Studies (etoposide) | Trials (etoposide) | Recent Studies (post-2010) (etoposide) |
|---|---|---|---|---|---|
| 10,147 | 26 | 3,657 | 18,306 | 3,693 | 4,900 |
| Protein | Taxonomy | hydroxyl radical (IC50) | etoposide (IC50) |
|---|---|---|---|
| nuclear receptor coactivator 1 isoform 1 [Homo sapiens] | Homo sapiens (human) | 1.153 | |
| nuclear receptor coactivator 3 isoform a | Homo sapiens (human) | 1.4284 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 3.187 | |
| Caspase-3 | Homo sapiens (human) | 1 | |
| DNA topoisomerase 2-beta | Homo sapiens (human) | 0.4299 | |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | 4.18 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Antholine, WM; Eliot, HM; Kalyanaraman, B; Sinha, BK | 1 |
| Eliot, HM; Kalayanaraman, B; Sinha, BK | 1 |
| Gao, D; Imakura, Y; Lee, KH; Sakurai, H; Takami, M; Tawa, R | 1 |
| Kaminskyy, VO; Piskunova, T; Tchevkina, EM; Zborovskaya, IB; Zhivotovsky, B | 1 |
4 other study(ies) available for hydroxyl radical and etoposide
| Article | Year |
|---|---|
Copper ion-dependent oxy-radical mediated DNA damage from dihydroxy derivative of etoposide.
Topics: Animals; Catalase; Copper; DNA Damage; Etoposide; Free Radicals; Hydrolysis; Hydroxides; Hydroxyl Radical; Superoxide Dismutase | 1990 |
Iron-dependent hydroxyl radical formation and DNA damage from a novel metabolite of the clinically active antitumor drug VP-16.
Topics: Breast Neoplasms; Cell Line; Cell Survival; DNA Damage; Drug Screening Assays, Antitumor; Electron Spin Resonance Spectroscopy; Etoposide; Female; Ferric Compounds; Free Radicals; Glutathione; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical | 1988 |
Binding affinity of Cu(II)-VP-16 (etoposide) complex and its analogues to DNA and hydroxyl radical generation during DNA strand breaks.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cattle; Circular Dichroism; Copper; DNA Damage; Etoposide; Hydroxyl Radical; Kinetics; Oxidation-Reduction | 1998 |
Suppression of basal autophagy reduces lung cancer cell proliferation and enhances caspase-dependent and -independent apoptosis by stimulating ROS formation.
Topics: Apoptosis; Autophagy; Carcinoma, Non-Small-Cell Lung; Caspases; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cisplatin; Drug Screening Assays, Antitumor; Etoposide; Free Radical Scavengers; Humans; Hydroxyl Radical; Lung Neoplasms; Membrane Potential, Mitochondrial; Mitochondrial Membranes; Permeability; Reactive Oxygen Species | 2012 |