Page last updated: 2024-09-04

hydroxyl radical and deoxyguanosine

hydroxyl radical has been researched along with deoxyguanosine in 102 studies

Compound Research Comparison

Studies (hydroxyl radical)	Trials (hydroxyl radical)	Recent Studies (post-2010) (hydroxyl radical)	Studies (deoxyguanosine)	Trials (deoxyguanosine)	Recent Studies (post-2010) (deoxyguanosine)
10,147	26	3,657	6,470	225	2,167

Research

Studies (102)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (2.94)	18.7374
1990's	38 (37.25)	18.2507
2000's	37 (36.27)	29.6817
2010's	20 (19.61)	24.3611
2020's	4 (3.92)	2.80

Authors

Authors	Studies
Dalal, NS; Gannett, PM; Shi, XG; Sun, XL	1
Floyd, RA; Park, JW	2
Dizdaroglu, M; Halliwell, B	1
Hernandez, L; Kasprzak, KS; North, SL	1
Chipman, JK; Faux, SP; Gao, M; Levy, LS	1
Akuzawa, S; Masuda, T; Ueno, Y; Yamaguchi, H	1
Chipman, JK; Davies, JE; Faux, SP; Smith, AJ; Winyard, PG	1
Ames, BN; Shigenaga, MK	1
Dalal, NS; Gannett, PM; Shi, XL; Toth, B	1
Eneff, K; Floyd, RA; Gutteridge, JM; West, M	1
Floyd, RA; Gutteridge, JM; Maidt, L; Price, S; Schneider, JE	1
Browning, MM; Eneff, KL; Floyd, RA; Schneider, JE; Zhu, X	1
Altmiller, DH; Floyd, RA; Rickard, RC; Watson, JJ; Wong, PK	1
Inanami, O; Kuwabara, M; Sato, F	1
Aust, SD; Spear, N	1
Fu, DJ; McLaughlin, LW; Rajur, SB	1
Costa, M; Dowjat, K; Huang, X; Kitahara, J; Zhitkovich, A	1
Almstadt, E; Appel, KE; Dahlhaus, M; Henschke, P; Lüttgert, S	1
Shi, X	1
Boveris, A; Cadenas, E; Giulivi, C	1
Almstadt, E; Appel, KE; Dahlhaus, M	1
Berger, M; Cadet, J; Constant, JF; Coulombeau, C; Laayoun, A; Lhomme, J	1
Birnboim, HC; Floyd, RA; Maidt, L; Raynor, T	1
Fischer-Nielsen, A; Jeding, IB; Loft, S	1
Jiang, JJ; Liu, KJ; Mao, Y; Shi, X	1
Jiang, H; Mao, Y; Saffiotti, U; Shi, X; Ye, J	1
Hiraku, Y; Kawanishi, S	1
Cadet, J; Douki, T	1
Adam, W; Andler, S; Saha-Möller, CR; Schönberger, A	1
Chen, F; Rojanasakul, Y; Shi, X; Ye, J; Zhang, X	1
Kuwabara, M; Matsuda, A; Ohshima, H; Ono, A; Sawamura, S	1
Cai, Q; Rahn, R; Wei, H; Zhang, X	1
Hill, J; Jackson, JH; Kuo, CY; Mitra, G; Rodriguez, H; Schwabacher, AW; Vollenweider, M	1
Chao, HT; Chen, CS; Pan, RL; Wei, YH	1
Baginski, TJ; Dykens, JA	1
Kawanishi, S; Oikawa, S	1
Chang, CY; Liu, TY; Wang, LC; Yang, JL	1
Cho, SH; Chung, MH; Kim, H	1
Arimoto, T; Kohno, M; Takano, H; Yoshikawa, T	1
Du, PC; Duh, PD; Yen, GC	1
Bretonniere, Y; Cadet, J; Douki, T	1
Bohannon, KE; Bruner, MW; Evans, RK; Volkin, DB; Wang, B; Xu, Z	1
Candeias, LP; Steenken, S	1
Hiraku, Y; Kawanishi, S; Murata, M; Ohnishi, S; Oikawa, S	1
Kim, RH; Park, JE; Park, JW	1
Kato, N; Morimoto, K; Takeuchi, T; Watanabe, K	1
Adam, W; Hartung, J; Okamoto, H; Saha-Möller, CR; Spehar, K	1
Degawa, M; Kawanishi, S; Murata, M; Ohnishi, S	1
Kawabata, T; Kondo, A; Kondo, T; Namba, M; Pu, H; Sakaguchi, M	1
Ashida, H; Danno, G; Kanazawa, K; Sakakibara, H; Sun, M	1
Hiai, H; Ishikawa, Y; Kume, M; Toyokuni, S; Yamagami, K; Yamamoto, Y; Yamaoka, Y	1
Jung, Y; Surh, Y	1
Harada, M; Ochi, T; Oya-Ohta, Y; Ueda, A; Yamamoto, K	1
Hirakawa, K; Hirosawa, I; Kawanishi, S; Oikawa, S	1
Choi, JY; Chung, MH; Doetsch, PW; Kim, JE; Kim, JS; You, HJ	1
Kim, RH; Kwon, OJ; Park, JW	1
Fukushima, S; Funae, Y; Imaoka, S; Kinoshita, A; Masuda, C; Morimura, K; Ogawa, M; Wanibuchi, H	1
Hofer, T; Möller, L	1
Chen, CL; Chi, CW; Liu, TY	1
Ito, H; Kawasaki, H; Kishimoto, Y; Maeta, Y; Miura, T; Mukoyama, T; Murawaki, Y; Nakai, Y; Oyama, K; Shiota, G; Udagawa, A; Yanagidani, A; Yashima, K	1
Iida, Y; Inanami, O; Kuwabara, M; Sawamura, S; Tsujitani, M; Yokoyama, K	1
Borm, PJ; Donaldson, K; Duffin, R; Höhr, D; Knaapen, AM; Schins, RP; Shi, T; Stone, V; Weishaupt, C	1
Kaneko, T; Tahara, S; Takabayashi, F	1
Frenkel, K; Huang, X; Maes, D; Mammone, T; Marenus, K; Pelle, E	1
Haneda, M; Htay, HH; Li, WH; Murakami, K; Naruse, M; Qiao, SL; Tsubouchi, R; Yokochi, T; Yoshino, M	1
Furihata, M; Hashimoto, K; Horino, T; Ito, H; Yamaguchi, T	1
Hiraku, Y; Inoue, S; Ito, K; Kawanishi, S	1
Hiraku, Y; Kawanishi, S; Mizutani, M; Murata, M; Oikawa, S; Sakano, K	1
Borm, PJ; Duffin, R; Li, H; Schins, RP; Shi, T; Weishaupt, C	1
Fiotakis, K; Valavanidis, A; Vlahoyianni, T	1
Fukushima, S; Kinoshita, A; Wanibuchi, H; Wei, M; Yunoki, T	1
Boussicault, F; Caminal, C; Chatgilialoglu, C; Kaloudis, P; Mulazzani, QG	1
Dizdaroglu, M; Jaruga, P	1
Anzai, K; Manda, K; Ueno, M	1
Aguar, M; Arduini, A; Asensi, MA; Brugada, M; Escrig, R; Ledo, A; Saenz, P; Sastre, J; Vento, M	1
Chatgilialoglu, C; D'Angelantonio, M; Guerra, M; Kaloudis, P; Mulazzani, QG	1
Inukai, M; Kurokawa, K; Moriwaki, N; Suzuki, T	1
Fujii, H; Igarashi, T; Machide, M; Oharazawa, H; Ohsawa, I; Ohta, S; Suzuki, H; Takahashi, H; Yokota, T	1
Auvré, F; Bergeron, F; Radicella, JP; Ravanat, JL	1
Barbati, S; Bonnefoy, A; Botta, A; Chiron, S	1
Hagiwara, S; Koga, H; Kusaka, J; Matsumoto, S; Nishida, T; Noguchi, T; Yokoi, I	1
Chatgilialoglu, C; Ferreri, C; Terzidis, MA	1
Hirasawa, T; Ishii, Y; Ito, R; Iwasaki, Y; Maruyama, Y; Nakazawa, H; Nishikawa, A; Saito, K; Umemura, T	1
Bobrowski, K; Chatgilialoglu, C; D'Angelantonio, M; Kciuk, G	1
Beach, DG; Gabryelski, W; Manderville, RA; Witham, AA	1
Song, Y; Wang, H; Yin, R; Zhang, D; Zhu, BZ	1
Abu Khadra, KM; Aljaberi, AM; Gagaa, MH; Issa, HS; Khalil, AM	1
Imase, M; Ishii, K; Oda, H; Ogasawara, Y; Wakabayashi, H	1
Hum Park, C; Ienaga, K; Yokozawa, T	1
Baldassarri, EJ; Chatgilialoglu, C; Fragneto, G; Mariani, P; Masiero, S; Pieraccini, S; Terzidis, MA	1
Nelson, BC; Petersen, EJ; Rabb, SA; Reipa, V; Stanley, DL; Watson, SS	1
Galisteo, J; Herraiz, T	1
Ajayakumar, MR; Alam, MJ; Ghaskadbi, S; Goswami, SK; Sharma, M; Thakur, A	1
Brooks, PJ	1
Gao, HY; Huang, CH; Li, F; Mao, L; Qin, L; Qu, N; Shao, B; Shao, J; Shen, C; Wang, YF; Xie, LN; Xu, D; Zhou, X; Zhu, BZ	1
Abe, M; Fujitaka, K; Fukuhara, K; Hamada, H; Hattori, N; Iwamoto, H; Kohno, N; Masuda, T; Nakashima, T	1
Bai, L; Deng, Z; Huang, Q; Liang, J; Shi, T; Wang, XL; Wang, Z; Wu, T; Zhao, YL	1
Tsuchida, N; Yamabe, S; Yamazaki, S	1
Dai, X; Greenberg, MM; Su, H; Zheng, L	1
Greenberg, MM; Zheng, L	1
Burrows, CJ; Fleming, AM	1

Reviews

5 review(s) available for hydroxyl radical and deoxyguanosine

Article	Year
The measurement of oxidative damage to DNA by HPLC and GC/MS techniques. Free radical research communications, 1992, Volume: 16, Issue:2 Topics: 8-Hydroxy-2'-Deoxyguanosine; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA Damage; Free Radicals; Gas Chromatography-Mass Spectrometry; Hydroxides; Hydroxyl Radical; Oxidation-Reduction	1992
8,5'-Cyclopurine-2'-deoxynucleosides in DNA: mechanisms of formation, measurement, repair and biological effects. DNA repair, 2008, Sep-01, Volume: 7, Issue:9 Topics: Animals; Chromatography, Liquid; Deoxyadenosines; Deoxyguanosine; DNA; DNA Repair; Gas Chromatography-Mass Spectrometry; Gene Expression Regulation; Humans; Hydroxyl Radical; Mass Spectrometry; Mice; Nucleic Acid Conformation	2008
Purine 5',8-cyclonucleoside lesions: chemistry and biology. Chemical Society reviews, 2011, Volume: 40, Issue:3 Topics: Cyclization; Deoxyadenosines; Deoxyguanosine; DNA Damage; Exoribonucleases; Hydroxyl Radical; Oxidation-Reduction; Stereoisomerism	2011
Daily hydroxyl radical scavenging capacity of mammals. Drug discoveries & therapeutics, 2014, Volume: 8, Issue:2 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Biomarkers; Creatinine; Deoxyguanosine; Free Radical Scavengers; Glomerular Filtration Rate; Humans; Hydroxyl Radical; Kidney; Kidney Failure, Chronic; Methylguanidine; Predictive Value of Tests; Rats; Severity of Illness Index; Time Factors	2014
The cyclopurine deoxynucleosides: DNA repair, biological effects, mechanistic insights, and unanswered questions. Free radical biology & medicine, 2017, Volume: 107 Topics: Animals; Deoxyadenosines; Deoxyguanosine; DNA; DNA Damage; DNA Repair; Humans; Hydroxyl Radical; Neurodegenerative Diseases; Risk; RNA Polymerase II; Skin Neoplasms; Transcription, Genetic; Ultraviolet Rays; Xeroderma Pigmentosum	2017

Other Studies

97 other study(ies) available for hydroxyl radical and deoxyguanosine

Article	Year
Deferoxamine inhibition of Cr(V)-mediated radical generation and deoxyguanine hydroxylation: ESR and HPLC evidence. Archives of biochemistry and biophysics, 1992, Volume: 293, Issue:2 Topics: Animals; Cattle; Chromates; Chromatography, High Pressure Liquid; Deferoxamine; Deoxyguanosine; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Hydroxylation; Oxidation-Reduction	1992
Lipid peroxidation products mediate the formation of 8-hydroxydeoxyguanosine in DNA. Free radical biology & medicine, 1992, Volume: 12, Issue:4 Topics: 8-Hydroxy-2'-Deoxyguanosine; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; DNA Damage; Free Radical Scavengers; Free Radicals; Hydroxides; Hydroxyl Radical; Lipid Peroxidation; Liposomes; Thiobarbiturates	1992
Reversal by nickel(II) of inhibitory effects of some scavengers of active oxygen species upon hydroxylation of 2'-deoxyguanosine in vitro. Chemico-biological interactions, 1992, Sep-14, Volume: 84, Issue:1 Topics: Ascorbic Acid; Deoxyguanosine; Ethanol; Free Radical Scavengers; Glutathione; Histidine; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Hydroxylation; Mannitol; Nickel; Oxidation-Reduction; Oxygen	1992
Production of 8-hydroxydeoxyguanosine in isolated DNA by chromium(VI) and chromium(V). Carcinogenesis, 1992, Volume: 13, Issue:9 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Cattle; Chromium; Deoxyguanosine; DNA; Glutathione; Hydroxides; Hydroxyl Radical; Oxidation-Reduction; Superoxides	1992
Radical-mediated modification of deoxyguanine and deoxyribose by luteoskyrin and related anthraquinones. Mutation research, 1992, Volume: 266, Issue:2 Topics: 3T3 Cells; 8-Hydroxy-2'-Deoxyguanosine; Animals; Anthraquinones; Cell Survival; Deoxyguanosine; Deoxyribose; Hydroxides; Hydroxyl Radical; Mice; Naphthoquinones	1992
Bleomycin-induced unscheduled DNA synthesis in non-permeabilized human and rat hepatocytes is not paralleled by 8-oxo-7,8-dihydrodeoxyguanosine formation. Biochemical pharmacology, 1992, Oct-06, Volume: 44, Issue:7 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Bleomycin; Deoxyguanosine; DNA; DNA Damage; Humans; Hydroxides; Hydroxyl Radical; Liver; Male; Malondialdehyde; Rats; Rats, Wistar	1992
Assays for 8-hydroxy-2'-deoxyguanosine: a biomarker of in vivo oxidative DNA damage. Free radical biology & medicine, 1991, Volume: 10, Issue:3-4 Topics: 8-Hydroxy-2'-Deoxyguanosine; Aging; Animals; Biomarkers; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; DNA Damage; DNA Repair; Free Radicals; Gamma Rays; Hydroxides; Hydroxyl Radical; Neoplasms, Experimental; Oxygen; Rats; Rats, Inbred F344	1991
8-Hydroxy-2'-deoxyguanosine formation during the catalytic oxidation of hydrazines in the presence of 2'-deoxyguanosine. Chemico-biological interactions, 1991, Volume: 80, Issue:1 Topics: 8-Hydroxy-2'-Deoxyguanosine; Chromatography, High Pressure Liquid; Cyclic N-Oxides; Deoxyguanosine; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrazines; Hydroxides; Hydroxyl Radical; Magnetic Resonance Spectroscopy; Spin Labels	1991
Bleomycin-iron damage to DNA with formation of 8-hydroxydeoxyguanosine and base propenals. Indications that xanthine oxidase generates superoxide from DNA degradation products. Free radical research communications, 1990, Volume: 10, Issue:3 Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Bleomycin; Cattle; Deoxyguanosine; DNA; DNA Damage; Electron Spin Resonance Spectroscopy; Free Radicals; Guanine; Hydroxides; Hydroxyl Radical; Iron; Superoxides; Thiobarbiturates; Xanthine Oxidase	1990
Methylene blue plus light mediates 8-hydroxy 2'-deoxyguanosine formation in DNA preferentially over strand breakage. Nucleic acids research, 1990, Feb-11, Volume: 18, Issue:3 Topics: 8-Hydroxy-2'-Deoxyguanosine; Catalase; Deferoxamine; Deoxyguanosine; DNA Damage; DNA, Superhelical; Free Radicals; Hydroxides; Hydroxyl Radical; Light; Magnesium; Mannitol; Methylene Blue; Plasmids; Thiopental; Thiourea	1990
Characterization of hydroxyl free radical mediated damage to plasmid pBR322 DNA. Mutation research, 1989, Volume: 214, Issue:1 Topics: Catalase; Deoxyguanosine; DNA Damage; DNA, Bacterial; DNA, Superhelical; Electrophoresis, Agar Gel; Escherichia coli; Free Radicals; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Kinetics; Oxygen Consumption; Plasmids; Salicylates	1989
Hydroxyl free radical adduct of deoxyguanosine: sensitive detection and mechanisms of formation. Free radical research communications, 1986, Volume: 1, Issue:3 Topics: 8-Hydroxy-2'-Deoxyguanosine; Chromatography, High Pressure Liquid; Deoxyguanosine; Electrochemistry; Ethanol; Free Radical Scavengers; Free Radicals; Hydroxyl Radical; Thiourea	1986
OH-induced free radicals in purine nucleosides and their homopolymers: e.s.r. and spin-trapping with 2-methyl-2-nitrosopropane. International journal of radiation biology and related studies in physics, chemistry, and medicine, 1986, Volume: 49, Issue:5 Topics: Adenosine; Chromatography, High Pressure Liquid; Deoxyadenosines; Deoxyguanosine; Electron Spin Resonance Spectroscopy; Guanosine; Hydroxides; Hydroxyl Radical; Inosine; Nitroso Compounds; Poly A; Poly I; Purine Nucleosides	1986
Effects of glutathione on Fenton reagent-dependent radical production and DNA oxidation. Archives of biochemistry and biophysics, 1995, Dec-01, Volume: 324, Issue:1 Topics: 8-Hydroxy-2'-Deoxyguanosine; Deoxyguanosine; DNA; DNA Damage; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Glutathione; Hydrogen Peroxide; Hydroxyl Radical; Iron; Oxidation-Reduction; Sulfhydryl Compounds	1995
Activity of the hammerhead ribozyme upon inversion of the stereocenters for the guanosine 2'-hydroxyls. Biochemistry, 1994, Nov-22, Volume: 33, Issue:46 Topics: Arabinose; Deoxyguanosine; Hydroxyl Radical; RNA; RNA, Catalytic; Stereoisomerism; Structure-Activity Relationship	1994
Heterochromatic proteins specifically enhance nickel-induced 8-oxo-dG formation. Carcinogenesis, 1995, Volume: 16, Issue:8 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Cricetinae; Cricetulus; Deoxyguanosine; Heterochromatin; Histones; Hydrogen Peroxide; Hydroxyl Radical; Male; Nickel; Nuclear Matrix; Nuclear Proteins	1995
Induction of 8-hydroxy-2-deoxyguanosine and single-strand breaks in DNA of V79 cells by tetrachloro-p-hydroquinone. Mutation research, 1995, Volume: 329, Issue:1 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Carcinogens, Environmental; Cells, Cultured; Cricetinae; Cricetulus; Deoxyguanosine; DNA Damage; DNA, Single-Stranded; Dose-Response Relationship, Drug; Fibroblasts; Hydroquinones; Hydroxyl Radical; Least-Squares Analysis; Lung; Oxidation-Reduction; Oxidative Stress; Pentachlorophenol; Reactive Oxygen Species	1995
Generation of SO3.- and OH radicals in SO3(2-) reactions with inorganic environmental pollutants and its implications to SO3(2-) toxicity. Journal of inorganic biochemistry, 1994, Nov-15, Volume: 56, Issue:3 Topics: 8-Hydroxy-2'-Deoxyguanosine; Chromatography, High Pressure Liquid; Cyclic N-Oxides; Deoxyguanosine; DNA Damage; Electrochemistry; Electron Spin Resonance Spectroscopy; Environmental Pollutants; Free Radicals; Hydrogen Peroxide; Hydroxyl Radical; Kinetics; Spin Labels; Sulfur Dioxide	1994
Hydroxyl radical generation during mitochondrial electron transfer and the formation of 8-hydroxydesoxyguanosine in mitochondrial DNA. Archives of biochemistry and biophysics, 1995, Feb-01, Volume: 316, Issue:2 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antimycin A; Cattle; Cellular Senescence; Chelating Agents; Cyclic N-Oxides; Deoxyguanosine; DNA, Mitochondrial; Electron Spin Resonance Spectroscopy; Electron Transport; Free Radicals; Hydrogen Peroxide; Hydroxyl Radical; Methacrylates; Mitochondria, Heart; Models, Chemical; Rotenone; Spin Labels; Submitochondrial Particles; Thiazoles	1995
The pentachlorophenol metabolite tetrachloro-p-hydroquinone induces the formation of 8-hydroxy-2-deoxyguanosine in liver DNA of male B6C3F1 mice. Toxicology letters, 1994, Volume: 74, Issue:3 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Deoxyguanosine; Diet; DNA; DNA Damage; Hydroquinones; Hydroxyl Radical; Injections, Intraperitoneal; Liver; Male; Mice; Oxidation-Reduction; Pentachlorophenol; Reactive Oxygen Species	1994
Aminothiols linked to quinoline and acridine chromophores efficiently decrease 7,8-dihydro-8-oxo-2'-deoxyguanosine formation in gamma-irradiated DNA. International journal of radiation biology, 1994, Volume: 66, Issue:3 Topics: 8-Hydroxy-2'-Deoxyguanosine; Acridines; Deoxyguanosine; DNA; Gamma Rays; Hydroxyl Radical; Intercalating Agents; Quinolines; Radiation-Protective Agents; Sulfhydryl Compounds	1994
8-Hydroxydeoxyguanosine in DNA from TPA-stimulated human granulocytes. Free radical research, 1994, Volume: 20, Issue:2 Topics: 8-Hydroxy-2'-Deoxyguanosine; Biomarkers; Deoxyguanosine; DNA; DNA Damage; Granulocytes; Humans; Hydroxyl Radical; In Vitro Techniques; Superoxides; Tetradecanoylphorbol Acetate	1994
Generation of strand breaks and formation of 8-hydroxy-2'-deoxyguanosine in DNA by a Thiol/Fe3+/O2-catalyzed oxidation system. Archives of biochemistry and biophysics, 1994, Volume: 312, Issue:1 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Catalysis; Cattle; Deoxyguanosine; Deuterium Oxide; DNA Damage; Enzymes; Ferric Compounds; Free Radical Scavengers; Hot Temperature; Hydrogen Peroxide; Hydroxyl Radical; Oxidation-Reduction; Oxygen; Sulfhydryl Compounds	1994
Radiation-induced formation of 8-hydroxy-2'-deoxyguanosine and its prevention by scavengers. Carcinogenesis, 1994, Volume: 15, Issue:8 Topics: 8-Hydroxy-2'-Deoxyguanosine; Aminosalicylic Acids; Animals; Ascorbic Acid; Cattle; Deoxyguanosine; Dose-Response Relationship, Radiation; Free Radical Scavengers; Glutathione; Hydroxyl Radical; Mesalamine	1994
Generation of reactive oxygen species by Co(II) from H2O2 in the presence of chelators in relation to DNA damage and 2'-deoxyguanosine hydroxylation. Journal of toxicology and environmental health, 1996, Volume: 47, Issue:1 Topics: Anserine; Azides; Chelating Agents; Chromatography, High Pressure Liquid; Cobalt; Deferoxamine; Deoxyguanosine; DNA Damage; Electron Spin Resonance Spectroscopy; Electrophoresis; Ethanol; Formates; Hydrogen Peroxide; Hydroxyl Radical; Hydroxylation; Mutagens; Oxidation-Reduction; Phenanthrolines; Reactive Oxygen Species; Sodium Azide; Spectrophotometry, Ultraviolet	1996
Vanadium(IV)-mediated free radical generation and related 2'-deoxyguanosine hydroxylation and DNA damage. Toxicology, 1996, Jan-08, Volume: 106, Issue:1-3 Topics: 8-Hydroxy-2'-Deoxyguanosine; Chelating Agents; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA Damage; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen Peroxide; Hydroxyl Radical; Hydroxylation; Kinetics; Lipid Peroxidation; Peroxides; Spectrophotometry, Ultraviolet; tert-Butylhydroperoxide; Vanadium	1996
Mechanism of oxidative DNA damage induced by delta-aminolevulinic acid in the presence of copper ion. Cancer research, 1996, Apr-15, Volume: 56, Issue:8 Topics: 8-Hydroxy-2'-Deoxyguanosine; Aminolevulinic Acid; Base Sequence; Catalase; Copper; Deoxyguanosine; DNA Damage; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Genes, ras; Hydroxyl Radical; Molecular Sequence Data; Oligodeoxyribonucleotides; Oxidation-Reduction; Phenanthrolines; Plasmids; Restriction Mapping	1996
Peroxynitrite mediated oxidation of purine bases of nucleosides and isolated DNA. Free radical research, 1996, Volume: 24, Issue:5 Topics: Deoxyadenosines; Deoxyguanosine; DNA; Gamma Rays; Hydroxyl Radical; In Vitro Techniques; Nitrates; Oxidation-Reduction; Purine Nucleosides; Radiation, Ionizing; Reactive Oxygen Species; Solutions; Water	1996
Inhibitory effect of ethyl oleate hydroperoxide and alcohol in photosensitized oxidative DNA damage. Journal of photochemistry and photobiology. B, Biology, 1996, Volume: 34, Issue:1 Topics: Animals; Cattle; Deoxyguanosine; DNA Damage; Guanine; Hydroxyl Radical; Molecular Structure; Oleic Acids; Oxidation-Reduction; Peroxides; Photosensitizing Agents; Xanthenes; Xanthones	1996
One-electron reduction of chromium(VI) by alpha-lipoic acid and related hydroxyl radical generation, dG hydroxylation and nuclear transcription factor-kappaB activation. Archives of biochemistry and biophysics, 1997, Feb-15, Volume: 338, Issue:2 Topics: Antioxidants; Carcinogens; Chromium; Deoxyguanosine; DNA-Binding Proteins; Electron Spin Resonance Spectroscopy; Humans; Hydroxyl Radical; Hydroxylation; NF-kappa B; Oxidation-Reduction; Thioctic Acid; Tumor Cells, Cultured	1997
Reactions between hydroxyl-radical-induced 7,8-dihydro-8-oxo-2'-deoxyguanosine precursor and the spin trap alpha-phenyl-N-tert-butylnitrone. Journal of radiation research, 1997, Volume: 38, Issue:1 Topics: 8-Hydroxy-2'-Deoxyguanosine; Chromatography, High Pressure Liquid; Cyclic N-Oxides; Deoxyguanosine; Electrochemistry; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Hydroxyl Radical; In Vitro Techniques; Nitrogen Oxides; Spin Labels	1997
Singlet oxygen involvement in ultraviolet (254 nm) radiation-induced formation of 8-hydroxy-deoxyguanosine in DNA. Free radical biology & medicine, 1997, Volume: 23, Issue:1 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Azides; Cattle; Deoxyguanosine; Deuterium Oxide; Dimethyl Sulfoxide; DNA; DNA Damage; Hydrogen Peroxide; Hydroxyl Radical; Iron; Mannitol; Oxygen; Singlet Oxygen; Sodium Azide; Thymus Gland; Ultraviolet Rays	1997
Stimulated human leukocytes cause activating mutations in the K-ras protooncogene. Oncogene, 1997, Jun-12, Volume: 14, Issue:23 Topics: 3T3 Cells; 8-Hydroxy-2'-Deoxyguanosine; Animals; Deoxyguanosine; DNA Damage; DNA, Neoplasm; Genes, ras; Humans; Hydroxyl Radical; Leukocytes; Lymphocyte Activation; Mice; Mutation; Plasmids; Purines; ras Proteins; Transfection; Xanthine Oxidase	1997
Hydroxyl radical-induced decline in motility and increase in lipid peroxidation and DNA modification in human sperm. Biochemistry and molecular biology international, 1997, Volume: 43, Issue:2 Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenosine Diphosphate; Deoxyguanosine; DNA; Ferrous Compounds; Humans; Hydrogen Peroxide; Hydroxyl Radical; Kinetics; Lipid Peroxidation; Male; Malondialdehyde; Sperm Motility; Spermatozoa; Xanthine; Xanthine Oxidase	1997
Urinary 8-hydroxydeoxyguanosine excretion as a non-invasive marker of neutrophil activation in animal models of inflammatory bowel disease. Scandinavian journal of gastroenterology, 1998, Volume: 33, Issue:6 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Chromatography, High Pressure Liquid; Deoxyguanosine; Dextran Sulfate; Enema; Hydroxyl Radical; Inflammatory Bowel Diseases; Intestines; Male; Neutrophil Activation; Peroxidase; Rats; Rats, Wistar; Trinitrobenzenesulfonic Acid	1998
Distinct mechanisms of site-specific DNA damage induced by endogenous reductants in the presence of iron(III) and copper(II). Biochimica et biophysica acta, 1998, Jul-30, Volume: 1399, Issue:1 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Ascorbic Acid; Cattle; Chlorides; Copper; Deoxyguanosine; DNA Damage; DNA Fragmentation; Ferric Compounds; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; NAD; Oxidation-Reduction	1998
Singlet oxygen is the major species participating in the induction of DNA strand breakage and 8-hydroxydeoxyguanosine adduct by lead acetate. Environmental and molecular mutagenesis, 1999, Volume: 33, Issue:3 Topics: 8-Hydroxy-2'-Deoxyguanosine; Catalase; Deoxyguanosine; Deuterium Oxide; DNA Adducts; DNA Damage; DNA, Superhelical; Dose-Response Relationship, Drug; Free Radical Scavengers; Half-Life; Hydrogen Peroxide; Hydroxyl Radical; Organometallic Compounds; Oxygen; Plasmids; Reactive Oxygen Species; Reducing Agents; Singlet Oxygen; Superoxide Dismutase; Zinc Acetate	1999
Exposure to hexavalent chromium does not increase 8-hydroxydeoxyguanosine levels in Korean chromate pigment workers. Industrial health, 1999, Volume: 37, Issue:3 Topics: 8-Hydroxy-2'-Deoxyguanosine; Air Pollutants, Occupational; Chromatography, High Pressure Liquid; Chromium; Deoxyguanosine; DNA; Environmental Monitoring; Female; Humans; Hydroxyl Radical; Korea; Lung; Male; Occupational Exposure	1999
Generation of reactive oxygen species and 8-hydroxy-2'-deoxyguanosine formation from diesel exhaust particle components in L1210 cells. Japanese journal of pharmacology, 1999, Volume: 80, Issue:1 Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylation; Animals; Cytochrome c Group; Deoxyguanosine; Electron Spin Resonance Spectroscopy; Enzyme-Linked Immunosorbent Assay; Hydroxyl Radical; Leukemia L1210; Male; Mice; Mice, Inbred DBA; Mice, Inbred ICR; Microsomes, Liver; NADH, NADPH Oxidoreductases; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Reactive Oxygen Species; Superoxides; Tumor Cells, Cultured; Vehicle Emissions	1999
Action of methanolic extract of mung bean hulls as inhibitors of lipid peroxidation and non-lipid oxidative damage. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1999, Volume: 37, Issue:11 Topics: Antioxidants; Deoxyguanosine; Drugs, Chinese Herbal; Fabaceae; Hydrogen Peroxide; Hydroxyl Radical; Iron Chelating Agents; Lipid Metabolism; Lipid Peroxidation; Lipids; Liposomes; Methanol; Oxidants; Oxidation-Reduction; Phospholipids; Plants, Medicinal	1999
Protection against radiation-induced degradation of DNA bases by polyamines. Radiation research, 2000, Volume: 153, Issue:1 Topics: 8-Hydroxy-2'-Deoxyguanosine; Amidines; Cytosine; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Dimethyl Sulfoxide; DNA; DNA Damage; Dose-Response Relationship, Drug; Gamma Rays; Gas Chromatography-Mass Spectrometry; Guanine; Hydroxyl Radical; Oxidation-Reduction; Polyamines; Purines; Putrescine; Pyrimidines; Radiation-Protective Agents; Solutions; Spermidine; Spermine	2000
Evaluation of degradation pathways for plasmid DNA in pharmaceutical formulations via accelerated stability studies. Journal of pharmaceutical sciences, 2000, Volume: 89, Issue:1 Topics: 8-Hydroxy-2'-Deoxyguanosine; Apurinic Acid; Buffers; Deoxyguanosine; DNA, Circular; DNA, Superhelical; Drug Stability; Drug Storage; Edetic Acid; Ethanol; Hydrogen-Ion Concentration; Hydroxyl Radical; Hydroxylation; Kinetics; Metals; Oxidation-Reduction; Phenylalanine; Phosphates; Plasmids; Predictive Value of Tests	2000
Reaction of HO* with guanine derivatives in aqueous solution: formation of two different redox-active OH-adduct radicals and their unimolecular transformation reactions. Properties of G(-H). Chemistry (Weinheim an der Bergstrasse, Germany), 2000, Feb-04, Volume: 6, Issue:3* Topics: Deoxyguanosine; DNA; Guanine; Hydrogen-Ion Concentration; Hydroxyl Radical; Models, Chemical; Oxidation-Reduction; Solutions; Spectrophotometry, Atomic	2000
Copper-dependent DNA damage induced by hydrazobenzene, an azobenzene metabolite. Free radical research, 2000, Volume: 32, Issue:6 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Azo Compounds; Catalase; Cattle; Chelating Agents; Copper; Deoxyguanosine; DNA; DNA Damage; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hydroxyl Radical; Oxidation-Reduction; Phenanthrolines; Phenylhydrazines; Piperidines	2000
Ceruloplasmin enhances DNA damage induced by hydrogen peroxide in vitro. Free radical research, 2000, Volume: 33, Issue:1 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Cattle; Ceruloplasmin; Copper; Deoxyguanosine; DNA Damage; Endopeptidases; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hydroxyl Radical; In Vitro Techniques; Oxidation-Reduction; Protein Conformation; Proteins	2000
Mechanism of oxidative DNA damage induction in a strict anaerobe, Prevotella melaninogenica. FEMS microbiology letters, 2000, Nov-01, Volume: 192, Issue:1 Topics: 8-Hydroxy-2'-Deoxyguanosine; Anaerobiosis; Deoxyguanosine; DNA Damage; Electron Spin Resonance Spectroscopy; Flow Cytometry; Hydrogen Peroxide; Hydroxyl Radical; Oxygen; Prevotella melaninogenica; Reactive Oxygen Species; Superoxides	2000
N-hydroxy-4-(4-chlorophenyl)thiazole-2(3H)-thione as a photochemical hydroxyl-radical source: photochemistry and oxidative damage of DNA (strand breaks) and 2'-deoxyguanosine (8-oxodG formation). Photochemistry and photobiology, 2000, Volume: 72, Issue:5 Topics: 8-Hydroxy-2'-Deoxyguanosine; Deoxyguanosine; DNA Damage; Hydroxyl Radical; In Vitro Techniques; Oxidation-Reduction; Photochemistry; Photolysis; Spectrophotometry; Thiazoles; Thiones	2000
Oxidative DNA damage induced by an N-hydroxy metabolite of carcinogenic 4-dimethylaminoazobenzene. Japanese journal of cancer research : Gann, 2001, Volume: 92, Issue:1 Topics: 8-Hydroxy-2'-Deoxyguanosine; Carcinogens; Catalase; Copper; Deoxyguanosine; DNA Adducts; DNA Damage; Hydrogen Peroxide; Hydroxyl Radical; NAD; Oxidation-Reduction; p-Aminoazobenzene; p-Dimethylaminoazobenzene	2001
Effects of oxygen concentrations on human fibroblasts treated with Fe(3+)-NTA. International journal of molecular medicine, 2001, Volume: 7, Issue:3 Topics: 8-Hydroxy-2'-Deoxyguanosine; Antioxidants; Blotting, Western; Catalase; Cell Line; Cell Survival; Deoxyguanosine; Ferric Compounds; Fibroblasts; Humans; Hydrogen Peroxide; Hydroxyl Radical; Immunohistochemistry; Mutagens; Nitrilotriacetic Acid; Oxygen; Reactive Oxygen Species; Superoxide Dismutase	2001
Dietary antioxidants fail in protection against oxidative genetic damage in in vitro evaluation. Bioscience, biotechnology, and biochemistry, 2000, Volume: 64, Issue:11 Topics: 8-Hydroxy-2'-Deoxyguanosine; Antimutagenic Agents; Antioxidants; Bepridil; Biphenyl Compounds; Carbolines; Deoxyguanosine; DNA, Bacterial; Flavonoids; Free Radical Scavengers; Hydroxyl Radical; Mutagenicity Tests; Phenols; Picrates; Polymers; Polyphenols; Salmonella	2000
Formation of 8-hydroxy-2'-deoxyguanosine and 4-hydroxy-2-nonenal-modified proteins in rat liver after ischemia-reperfusion: distinct localization of the two oxidatively modified products. Antioxidants & redox signaling, 2000,Spring, Volume: 2, Issue:1 Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Blotting, Western; Body Temperature; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA Adducts; DNA Damage; Hepatocytes; Hydroxyl Radical; Immunoenzyme Techniques; Ischemia; Liver; Liver Function Tests; Male; Molecular Weight; Nuclear Proteins; Oxidation-Reduction; Oxidative Stress; Proteins; Rats; Rats, Wistar; Reperfusion Injury; Specific Pathogen-Free Organisms; Time Factors	2000
Oxidative DNA damage and cytotoxicity induced by copper-stimulated redox cycling of salsolinol, a neurotoxic tetrahydroisoquinoline alkaloid. Free radical biology & medicine, 2001, Jun-15, Volume: 30, Issue:12 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Biomarkers; Catalase; Cattle; Chelating Agents; Copper; Deoxyguanosine; DNA Damage; DNA, Bacterial; DNA, Neoplasm; DNA, Superhelical; DNA, Viral; Drug Synergism; Free Radical Scavengers; Glutathione; Hydroxyl Radical; Isoquinolines; Neurotoxins; Oxidation-Reduction; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species; Salicylic Acid	2001
The biological activity of hydrogen peroxide VII. L-Histidine increases incorporation of H(2)O(2) into cells and enhances formation of 8-oxodeoxyguanosine by UV-C plus H(2)O(2) but not by H(2)O(2) alone. Mutation research, 2001, Jul-01, Volume: 478, Issue:1-2 Topics: 8-Hydroxy-2'-Deoxyguanosine; Cell-Free System; Cells, Cultured; Deoxyguanosine; DNA Adducts; Dose-Response Relationship, Drug; Drug Synergism; Histidine; Humans; Hydrogen Peroxide; Hydroxyl Radical; Time Factors; Ultraviolet Rays	2001
Site specificity and mechanism of oxidative DNA damage induced by carcinogenic catechol. Carcinogenesis, 2001, Volume: 22, Issue:8 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Carcinogens; Catalase; Catechols; Cattle; Cell Line; Copper; Deoxyguanosine; DNA; DNA Damage; Free Radical Scavengers; Humans; Hydroxyl Radical; NAD; Oxidative Stress; Phenanthrolines; Proto-Oncogene Mas	2001
Ntg2 of Saccharomyces cerevisiae repairs the oxidation products of 8-hydroxyguanine. Biochemical and biophysical research communications, 2001, Aug-03, Volume: 285, Issue:5 Topics: Borohydrides; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; DNA; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA-Formamidopyrimidine Glycosylase; Dose-Response Relationship, Radiation; Escherichia coli Proteins; Gamma Rays; Guanine; Hydrogen Peroxide; Hydroxyl Radical; Iron; Macromolecular Substances; N-Glycosyl Hydrolases; Oxidation-Reduction; Piperidines; Protein Binding; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Substrate Specificity; Thymidine	2001
Ceruloplasmin enhances DNA damage induced by cysteine/iron in vitro. Biochimie, 2001, Volume: 83, Issue:6 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Cattle; Ceruloplasmin; Copper; Cysteine; Deoxyguanosine; DNA; DNA Damage; Endopeptidases; Free Radical Scavengers; Hydroxyl Radical; In Vitro Techniques; Iron; Mutation; Oxidants; Oxidative Stress; Protein Conformation; Reactive Oxygen Species	2001
Formation of 8-hydroxydeoxyguanosine and cell-cycle arrest in the rat liver via generation of oxidative stress by phenobarbital: association with expression profiles of p21(WAF1/Cip1), cyclin D1 and Ogg1. Carcinogenesis, 2002, Volume: 23, Issue:2 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Apoptosis; Aryl Hydrocarbon Hydroxylases; Carcinogens; Cell Cycle; Cell Division; Cell Nucleus; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Cytoplasm; Deoxyguanosine; DNA Damage; DNA Repair; DNA-Formamidopyrimidine Glycosylase; DNA, Single-Stranded; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hepatocytes; Hydroxyl Radical; Immunohistochemistry; Liver; Male; Microsomes, Liver; N-Glycosyl Hydrolases; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Phenobarbital; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Steroid Hydroxylases; Time Factors	2002
Optimization of the workup procedure for the analysis of 8-oxo-7,8-dihydro-2'-deoxyguanosine with electrochemical detection. Chemical research in toxicology, 2002, Volume: 15, Issue:3 Topics: 8-Hydroxy-2'-Deoxyguanosine; Alkanesulfonic Acids; Animals; Antioxidants; Cells, Cultured; Cold Temperature; Deoxyguanosine; DNA; Electrochemistry; Guanidines; Humans; Hydroxyl Radical; Liver; Lymphocytes; Male; Methods; Organometallic Compounds; Rats; Thiocyanates	2002
Hydroxyl radical formation and oxidative DNA damage induced by areca quid in vivo. Journal of toxicology and environmental health. Part A, 2002, Volume: 65, Issue:3-4 Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Oral; Adult; Animals; Areca; Cricetinae; Deoxyguanosine; DNA Damage; Female; Humans; Hydroxyl Radical; Male; Mastication; Mouth Mucosa; Oxidative Stress; Saliva; Tyrosine	2002
Effects of Sho-Saiko-to on hepatocarcinogenesis and 8-hydroxy-2'-deoxyguanosine formation. Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:5 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anticarcinogenic Agents; Biomarkers, Tumor; Cell Count; Deoxyguanosine; Drugs, Chinese Herbal; Glutathione Transferase; Hydroxyl Radical; Liver Neoplasms; Male; Ornithine Decarboxylase; Oxidative Stress; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344	2002
Radiation-chemical properties of the hypoxic cell radiosensitizer doranidazole (PR-350). Journal of radiation research, 2002, Volume: 43, Issue:1 Topics: 8-Hydroxy-2'-Deoxyguanosine; Deoxyguanosine; DNA; DNA Adducts; DNA Damage; Hydroxyl Radical; Imidazoles; In Vitro Techniques; Pulse Radiolysis; Radiation-Sensitizing Agents; Radiochemistry	2002
Surface modification of quartz inhibits toxicity, particle uptake, and oxidative DNA damage in human lung epithelial cells. Chemical research in toxicology, 2002, Volume: 15, Issue:9 Topics: Cell Survival; Cells, Cultured; Comet Assay; Deoxyguanosine; DNA Damage; Electron Spin Resonance Spectroscopy; Epithelial Cells; Humans; Hydroxyl Radical; Immunohistochemistry; L-Lactate Dehydrogenase; Lung; Oxidation-Reduction; Particle Size; Quartz; Surface Properties	2002
Suppression of lipid hydroperoxide-induced oxidative damage to cellular DNA by esculetin. Biological & pharmaceutical bulletin, 2003, Volume: 26, Issue:6 Topics: 8-Hydroxy-2'-Deoxyguanosine; Antioxidants; Cations; Cell Line; Deoxyguanosine; DNA Damage; Esculin; Ferric Compounds; Humans; Hydroxyl Radical; Linoleic Acids; Lipid Peroxides; Oxidative Stress; Umbelliferones	2003
Ultraviolet-B-induced oxidative DNA base damage in primary normal human epidermal keratinocytes and inhibition by a hydroxyl radical scavenger. The Journal of investigative dermatology, 2003, Volume: 121, Issue:1 Topics: 8-Hydroxy-2'-Deoxyguanosine; Antineoplastic Agents; Antioxidants; beta Carotene; Cells, Cultured; Deoxyguanosine; Diuretics, Osmotic; DNA Damage; Epidermal Cells; Epidermis; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hydroxyl Radical; Keratinocytes; Mannitol; Oxidation-Reduction; Salicylates; Thiourea; Ultraviolet Rays	2003
Prooxidant activity of curcumin: copper-dependent formation of 8-hydroxy-2'-deoxyguanosine in DNA and induction of apoptotic cell death. Toxicology in vitro : an international journal published in association with BIBRA, 2004, Volume: 18, Issue:6 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cattle; Copper; Curcumin; Deoxyguanosine; DNA Damage; Flow Cytometry; HL-60 Cells; Humans; Hydroxyl Radical; Oxidants; Plasmids; Reactive Oxygen Species; Thymus Gland	2004
Suppressive effects of iron on TGF-beta1 production by renal proximal tubular epithelial cells. Nephron. Experimental nephrology, 2005, Volume: 100, Issue:1 Topics: 8-Hydroxy-2'-Deoxyguanosine; Acute Disease; Cell Culture Techniques; Deoxyguanosine; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Fibrosis; Humans; Hydroxyl Radical; Immunohistochemistry; Inflammation; Iron; Kidney; Kidney Diseases; Kidney Tubules, Proximal; Oxidants; Oxidative Stress; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1	2005
Mechanism of site-specific DNA damage induced by ozone. Mutation research, 2005, Aug-01, Volume: 585, Issue:1-2 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Catalase; Cattle; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; DNA Damage; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Genes, ras; Humans; Hydroxyl Radical; Luminescent Measurements; Ozone; Phosphorus Radioisotopes; Superoxide Dismutase	2005
Procyanidin B2 has anti- and pro-oxidant effects on metal-mediated DNA damage. Free radical biology & medicine, 2005, Oct-15, Volume: 39, Issue:8 Topics: 8-Hydroxy-2'-Deoxyguanosine; Antioxidants; Biflavonoids; Catechin; Cations, Divalent; Copper; Deoxyguanosine; DNA; DNA Damage; HL-60 Cells; Humans; Hydrogen Peroxide; Hydroxyl Radical; Iron; Oxidants; Proanthocyanidins	2005
Hydroxyl-radical-dependent DNA damage by ambient particulate matter from contrasting sampling locations. Environmental research, 2006, Volume: 101, Issue:1 Topics: 8-Hydroxy-2'-Deoxyguanosine; Air Pollutants; Cell Line; Deoxyguanosine; DNA; DNA Damage; Dust; Electron Spin Resonance Spectroscopy; Environmental Monitoring; Germany; Humans; Hydroxyl Radical; Particle Size	2006
Comparative study of the formation of oxidative damage marker 8-hydroxy-2'-deoxyguanosine (8-OHdG) adduct from the nucleoside 2'-deoxyguanosine by transition metals and suspensions of particulate matter in relation to metal content and redox reactivity. Free radical research, 2005, Volume: 39, Issue:10 Topics: 8-Hydroxy-2'-Deoxyguanosine; Biomarkers; Buffers; Chromatography, High Pressure Liquid; Deoxyguanosine; Edetic Acid; Electron Spin Resonance Spectroscopy; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxyl Radical; Metals; Molecular Structure; Oxidation-Reduction; Oxidative Stress; Solutions; Transition Elements	2005
Elevation of 8-hydroxydeoxyguanosine and cell proliferation via generation of oxidative stress by organic arsenicals contributes to their carcinogenicity in the rat liver and bladder. Toxicology and applied pharmacology, 2007, Jun-15, Volume: 221, Issue:3 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Arsenic Poisoning; Arsenicals; Carcinogenicity Tests; Carcinogens; Cell Proliferation; Cytochrome P-450 Enzyme System; Deoxyguanosine; Gene Expression Regulation; Hydroxyl Radical; Liver; Male; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Rats; Rats, Inbred F344; Urinary Bladder	2007
The fate of C5' radicals of purine nucleosides under oxidative conditions. Journal of the American Chemical Society, 2008, Jul-02, Volume: 130, Issue:26 Topics: Deoxyadenosines; Deoxyguanosine; Free Radicals; Hydroxyl Radical; Oxygen; Purine Nucleosides	2008
Cranial irradiation-induced inhibition of neurogenesis in hippocampal dentate gyrus of adult mice: attenuation by melatonin pretreatment. Journal of pineal research, 2009, Volume: 46, Issue:1 Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Analysis of Variance; Animals; Cranial Irradiation; Dentate Gyrus; Deoxyguanosine; Doublecortin Domain Proteins; Doublecortin Protein; Hydroxyl Radical; Immunohistochemistry; Ki-67 Antigen; Male; Melatonin; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Neurogenesis; Neuropeptides; Oxidative Stress; Photomicrography	2009
Human milk enhances antioxidant defenses against hydroxyl radical aggression in preterm infants. The American journal of clinical nutrition, 2009, Volume: 89, Issue:1 Topics: 8-Hydroxy-2'-Deoxyguanosine; Analysis of Variance; Antioxidants; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Cohort Studies; Deoxyguanosine; DNA Damage; Female; Gestational Age; Humans; Hydroxyl Radical; Infant Formula; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature; Male; Milk, Human; Oxidative Stress; Phenylalanine; Reactive Oxygen Species; Tandem Mass Spectrometry	2009
A reevaluation of the ambident reactivity of the guanine moiety towards hydroxyl radicals. Angewandte Chemie (International ed. in English), 2009, Volume: 48, Issue:12 Topics: Deoxyguanosine; Guanine; Hydroxyl Radical	2009
Effects of bromide upon reaction of nucleosides with hydrogen peroxide induced by ultraviolet light. Bioorganic & medicinal chemistry letters, 2009, Jun-15, Volume: 19, Issue:12 Topics: Bromides; Deoxyguanosine; Deoxyribonucleosides; Free Radicals; Hydrogen Peroxide; Hydroxyl Radical; Ultraviolet Rays	2009
Protection of the retina by rapid diffusion of hydrogen: administration of hydrogen-loaded eye drops in retinal ischemia-reperfusion injury. Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:1 Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Apoptosis; Biomarkers; Deoxyguanosine; Diffusion; Disease Models, Animal; Hydrogen; Hydroxyl Radical; Immunoenzyme Techniques; In Situ Nick-End Labeling; Male; Microscopy, Confocal; Neuroglia; Ophthalmic Solutions; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Retinal Diseases; Retinal Neurons; Vitreous Body	2010
HO* radicals induce an unexpected high proportion of tandem base lesions refractory to repair by DNA glycosylases. Proceedings of the National Academy of Sciences of the United States of America, 2010, Mar-23, Volume: 107, Issue:12 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Cattle; Deoxyadenosines; Deoxyguanosine; DNA; DNA Damage; DNA Glycosylases; DNA Repair; Gamma Rays; Hydroxyl Radical; In Vitro Techniques; Models, Biological; Oxidation-Reduction	2010
Secondary oxidation of cyclic 1,N2-propano and 1,N2-etheno-2'-deoxyguanosine DNA adducts. Consequences in oxidative stress biomarker development. Chemosphere, 2010, Volume: 80, Issue:9 Topics: Biomarkers; Chromatography, High Pressure Liquid; Deoxyadenosines; Deoxyguanosine; DNA Adducts; Environmental Monitoring; Hydrogen-Ion Concentration; Hydroxyl Radical; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Occupational Exposure; Oxidation-Reduction; Oxidative Stress	2010
Human atrial natriuretic peptide attenuates renal ischemia-reperfusion injury. The Journal of surgical research, 2012, Volume: 173, Issue:2 Topics: 8-Hydroxy-2'-Deoxyguanosine; Acute Kidney Injury; Animals; Atrial Natriuretic Factor; Biomarkers; Blood Urea Nitrogen; Cell Line; Deoxyguanosine; Humans; Hydroxyl Radical; Kidney; Male; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury	2012
Effect of interaction between phenolic compounds and copper ion on antioxidant and pro-oxidant activities. Toxicology in vitro : an international journal published in association with BIBRA, 2011, Volume: 25, Issue:7 Topics: 8-Hydroxy-2'-Deoxyguanosine; Biphenyl Compounds; Copper; Deoxyguanosine; DNA; DNA Damage; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Hydroxyl Radical; Phenols; Picrates	2011
New insights into the reaction paths of hydroxyl radicals with 2'-deoxyguanosine. Chemical research in toxicology, 2011, Dec-19, Volume: 24, Issue:12 Topics: Cyclization; Deoxyguanosine; DNA Adducts; DNA Damage; Hydroxyl Radical; Spectrophotometry, Ultraviolet	2011
Hydroxyl radical-induced oxidation of a phenolic C-linked 2'-deoxyguanosine adduct yields a reactive catechol. Chemical research in toxicology, 2012, Feb-20, Volume: 25, Issue:2 Topics: Acetylcysteine; Catechols; Copper; Deoxyguanosine; DNA Adducts; Edetic Acid; Ferrous Compounds; Hydrogen Peroxide; Hydroxyl Radical; Phenols	2012
Potent DNA damage by polyhalogenated quinones and H₂O₂ via a metal-independent and Intercalation-enhanced oxidation mechanism. Scientific reports, 2013, Volume: 3 Topics: 8-Hydroxy-2'-Deoxyguanosine; Deoxyguanosine; DNA; DNA Damage; Halogenation; Hydrogen Peroxide; Hydroxyl Radical; Intercalating Agents; Metals; Oxidation-Reduction; Quinones	2013
Assessment of oxidant/antioxidant status in saliva of cell phone users. Electromagnetic biology and medicine, 2014, Volume: 33, Issue:2 Topics: 8-Hydroxy-2'-Deoxyguanosine; Absorption, Radiation; Antioxidants; Cell Phone; Deoxyguanosine; Humans; Hydroxyl Radical; Male; Malondialdehyde; Oxidants; Oxidative Stress; Radio Waves; Reactive Oxygen Species; Saliva; Time Factors; Young Adult	2014
Lactoferrin directly scavenges hydroxyl radicals and undergoes oxidative self-degradation: a possible role in protection against oxidative DNA damage. International journal of molecular sciences, 2014, Jan-14, Volume: 15, Issue:1 Topics: 8-Hydroxy-2'-Deoxyguanosine; Deoxyguanosine; DNA; DNA Damage; Free Radical Scavengers; Hydroxyl Radical; Lactoferrin	2014
A lipophilic "fully-anti" dodecamer from a (5'S)-5',8-cyclo-2'-deoxyguanosine. Chemical communications (Cambridge, England), 2014, Sep-21, Volume: 50, Issue:73 Topics: Circular Dichroism; Deoxyguanosine; DNA; Hydroxyl Radical; Magnetic Resonance Spectroscopy; Molecular Conformation; Neutron Diffraction; Scattering, Small Angle	2014
DNA damaging potential of photoactivated p25 titanium dioxide nanoparticles. Chemical research in toxicology, 2014, Oct-20, Volume: 27, Issue:10 Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; DNA Damage; Electron Spin Resonance Spectroscopy; Gas Chromatography-Mass Spectrometry; Hydroxyl Radical; Light; Metal Nanoparticles; Tandem Mass Spectrometry; Titanium; Ultraviolet Rays	2014
Hydroxyl radical reactions and the radical scavenging activity of β-carboline alkaloids. Food chemistry, 2015, Apr-01, Volume: 172 Topics: 8-Hydroxy-2'-Deoxyguanosine; Alkaloids; Antioxidants; Ascorbic Acid; Carbolines; Chromatography, High Pressure Liquid; Deoxyguanosine; Hydrogen Peroxide; Hydroxyl Radical; Melatonin; Oxidative Stress; Oxidopamine	2015
Norepinephrine-induced apoptotic and hypertrophic responses in H9c2 cardiac myoblasts are characterized by different repertoire of reactive oxygen species generation. Redox biology, 2015, Volume: 5 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Apoptosis; Catalase; Cell Line; Deoxyguanosine; DNA Damage; Enzyme-Linked Immunosorbent Assay; Hydrogen Peroxide; Hydroxyl Radical; Microscopy, Fluorescence; Myoblasts, Cardiac; Norepinephrine; Rats; Reactive Oxygen Species; Superoxide Dismutase	2015
Mechanism of synergistic DNA damage induced by the hydroquinone metabolite of brominated phenolic environmental pollutants and Cu(II): Formation of DNA-Cu complex and site-specific production of hydroxyl radicals. Free radical biology & medicine, 2017, Volume: 104 Topics: 8-Hydroxy-2'-Deoxyguanosine; Chelating Agents; Copper; Deoxyguanosine; DNA Breaks, Double-Stranded; DNA Damage; Drinking Water; Environmental Pollutants; Humans; Hydroquinones; Hydroxyl Radical; Nitriles; Oxidation-Reduction; Phenanthrolines; Phenols; Polybrominated Biphenyls; Reactive Oxygen Species; Superoxide Dismutase	2017
Suplatast tosilate protects the lung against hyperoxic lung injury by scavenging hydroxyl radicals. Free radical biology & medicine, 2017, Volume: 106 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Arylsulfonates; Asthma; Bleomycin; Bronchoalveolar Lavage Fluid; Chemokine CCL2; Deoxyguanosine; DNA Damage; Humans; Hydroxyl Radical; Interleukin-6; Lipid Peroxidation; Lung; Lung Injury; Mice; Oxidative Stress; Reactive Oxygen Species; Sulfonium Compounds; Th2 Cells	2017
Mechanistic Investigation on ROS Resistance of Phosphorothioated DNA. Scientific reports, 2017, 02-20, Volume: 7 Topics: 8-Hydroxy-2'-Deoxyguanosine; Deoxyguanosine; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Gas Chromatography-Mass Spectrometry; Hydroxyl Radical; Oxidative Stress; Phosphates; Quantum Theory; Reactive Oxygen Species	2017
DFT Study of the Hydroxyl Radical Addition to 2'-Deoxyguanosine and the Guanine Base in Four Double-Stranded B-Form Dimers. The journal of physical chemistry. B, 2020, 02-27, Volume: 124, Issue:8 Topics: Density Functional Theory; Deoxyguanosine; Dimerization; Guanine; Hydroxyl Radical	2020
Independent Generation and Time-Resolved Detection of 2'-Deoxyguanosin-N2-yl Radicals. Angewandte Chemie (International ed. in English), 2020, 08-03, Volume: 59, Issue:32 Topics: Deoxyguanosine; Free Radicals; Hydroxyl Radical; Photolysis; Spectrophotometry, Ultraviolet; Ultraviolet Rays	2020
Independent Generation and Reactivity of 2'-Deoxyguanosin- The Journal of organic chemistry, 2020, 07-02, Volume: 85, Issue:13 Topics: 8-Hydroxy-2'-Deoxyguanosine; Deoxyguanosine; DNA Damage; Hydroxyl Radical; Oxidation-Reduction	2020
Iron Fenton oxidation of 2'-deoxyguanosine in physiological bicarbonate buffer yields products consistent with the reactive oxygen species carbonate radical anion not the hydroxyl radical. Chemical communications (Cambridge, England), 2020, Aug-25, Volume: 56, Issue:68 Topics: Anions; Bicarbonates; Carbonates; Deoxyadenosines; Deoxyguanosine; Free Radicals; Hydrogen Peroxide; Hydroxyl Radical; Iron; Oxidation-Reduction; Reactive Oxygen Species	2020