Page last updated: 2024-09-04

hydroxyl radical and deferiprone

hydroxyl radical has been researched along with deferiprone in 5 studies

Compound Research Comparison

Studies
(hydroxyl radical)
Trials
(hydroxyl radical)
Recent Studies (post-2010)
(hydroxyl radical)
Studies
(deferiprone)
Trials
(deferiprone)
Recent Studies (post-2010) (deferiprone)
10,147263,6571,016142409

Protein Interaction Comparison

ProteinTaxonomyhydroxyl radical (IC50)deferiprone (IC50)
Lysine-specific demethylase 6AHomo sapiens (human)4.2
Lysine-specific demethylase 4AHomo sapiens (human)3.275
Lysine-specific demethylase 5CHomo sapiens (human)5.6
Lysine-specific demethylase 2BHomo sapiens (human)8.1
Deoxyhypusine hydroxylaseHomo sapiens (human)5
Lysine-specific demethylase 2AHomo sapiens (human)6.8

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abdallah, MA; Brissot, P; Cillard, J; Cillard, P; Lescoat, G; Morel, I; Ocaktan, AZ; Pasdeloup, N; Sergent, O1
Brissot, P; Chantrel-Groussard, K; Gaboriau, F; Hider, RC; Lescoat, G; Loyer, P; Pasdeloup, N; Rakba, N1
Devanur, LD; Hider, RC; Neubert, H1
Kobzeva, TV; Kontoghiorghes, GJ; Polyakov, NE; Timoshnikov, VA1
Kobzeva, T; Kontoghiorghes, GJ; Polyakov, NE; Selyutina, OY; Timoshnikov, VA1

Other Studies

5 other study(ies) available for hydroxyl radical and deferiprone

ArticleYear
Antioxidant and free radical scavenging activities of the iron chelators pyoverdin and hydroxypyrid-4-ones in iron-loaded hepatocyte cultures: comparison of their mechanism of protection with that of desferrioxamine.
    Free radical biology & medicine, 1992, Volume: 13, Issue:5

    Topics: Animals; Antioxidants; Calcium-Binding Proteins; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclic N-Oxides; Deferiprone; Deferoxamine; Ethanol; Free Radical Scavengers; Free Radicals; Hydroxides; Hydroxyl Radical; Iron; Iron Chelating Agents; Kinetics; Lipid Peroxidation; Liver; Malondialdehyde; Oligopeptides; Photolysis; Pigments, Biological; Pyridones; Rats; Rats, Sprague-Dawley

1992
Iron mobilization, cytoprotection, and inhibition of cell proliferation in normal and transformed rat hepatocyte cultures by the hydroxypyridinone CP411, compared to CP20: a biological and physicochemical study.
    Biochemical pharmacology, 2004, Apr-15, Volume: 67, Issue:8

    Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Division; Cells, Cultured; Cytoprotection; Deferiprone; Hepatocytes; Hydroxyl Radical; Iron; Iron Chelating Agents; Male; Mass Spectrometry; Piperidines; Pyridones; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured

2004
The fenton activity of iron(III) in the presence of deferiprone.
    Journal of pharmaceutical sciences, 2008, Volume: 97, Issue:4

    Topics: Ascorbic Acid; Deferiprone; Edetic Acid; Hydrogen Peroxide; Hydroxyl Radical; Iron; Iron Chelating Agents; Oxidation-Reduction; Pyridones; Spectrometry, Mass, Electrospray Ionization

2008
Inhibition of Fe(2+)- and Fe(3+)- induced hydroxyl radical production by the iron-chelating drug deferiprone.
    Free radical biology & medicine, 2015, Volume: 78

    Topics: Deferiprone; Electron Spin Resonance Spectroscopy; Humans; Hydroxyl Radical; Iron; Iron Chelating Agents; Oxidation-Reduction; Pyridones; Reactive Oxygen Species; Spin Trapping; Ultraviolet Rays

2015
Effective inhibition of copper-catalyzed production of hydroxyl radicals by deferiprone.
    Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2019, Volume: 24, Issue:3

    Topics: Catalysis; Chelating Agents; Copper; Deferiprone; Hydroxyl Radical; Linoleic Acid; Lipid Peroxidation; Oxidation-Reduction

2019