hydroxyl radical has been researched along with daunorubicin in 13 studies
| Studies (hydroxyl radical) | Trials (hydroxyl radical) | Recent Studies (post-2010) (hydroxyl radical) | Studies (daunorubicin) | Trials (daunorubicin) | Recent Studies (post-2010) (daunorubicin) |
|---|---|---|---|---|---|
| 10,147 | 26 | 3,657 | 8,239 | 886 | 1,310 |
| Protein | Taxonomy | hydroxyl radical (IC50) | daunorubicin (IC50) |
|---|---|---|---|
| 72 kDa type IV collagenase | Homo sapiens (human) | 1.9 | |
| Multidrug resistance-associated protein 1 | Homo sapiens (human) | 8 | |
| Histone deacetylase 1 | Homo sapiens (human) | 0.047 | |
| Histone deacetylase 8 | Homo sapiens (human) | 0.22 | |
| Histone deacetylase 6 | Homo sapiens (human) | 0.02 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (53.85) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fisher, GR; Gutierrez, PL; Oldcorne, MA; Patterson, LH | 1 |
| Dikalov, SI; Frolova, EI; Godovikova, TS; Rumyantseva, GV; Sergejev, DS; Weiner, LM; Zarytova, VF | 1 |
| Collins, C; Dusre, L; Myers, CE; Sinha, BK | 1 |
| Alegria, AE; Riesz, P | 1 |
| Gianni, L; Muindi, J; Myers, C; Sinha, BK | 1 |
| Davies, KJ; Doroshow, JH | 1 |
| Glover, GP; Mariam, YH | 1 |
| Bredehorst, R; Panneerselvam, M; Vogel, CW | 1 |
| Muindi, JR; Myers, CE; Sinha, BK; Zweier, J | 1 |
| Weiner, LM | 1 |
| Ikeda, K; Kajiwara, K; Kishida, E; Kojo, S; Masuzawa, Y; Tanabe, E; Tokumaru, S | 1 |
| Hashimoto, R; Ikeda, K; Kajiwara, K; Kojo, S; Kuroi, R; Tokumaru, S | 1 |
| Fokt, I; Fox, KR; Phelps, RJ; Priebe, W; Webster, R | 1 |
13 other study(ies) available for hydroxyl radical and daunorubicin
| Article | Year |
|---|---|
NAD(P)H (quinone acceptor) oxidoreductase (DT-diaphorase)-mediated two-electron reduction of anthraquinone-based antitumour agents and generation of hydroxyl radicals.
Topics: Animals; Anthraquinones; Antineoplastic Agents; Daunorubicin; Dose-Response Relationship, Drug; Hydroxides; Hydroxyl Radical; Kinetics; Liver; Mitoxantrone; NAD(P)H Dehydrogenase (Quinone); NADP; Oxidation-Reduction; Rats; Structure-Activity Relationship; Superoxides | 1992 |
Hydroxyl radical generation by oligonucleotide derivatives of anthracycline antibiotic and synthetic quinone.
Topics: Base Sequence; Cyclic N-Oxides; Daunorubicin; Electron Spin Resonance Spectroscopy; Hydroxides; Hydroxyl Radical; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; NADPH-Ferrihemoprotein Reductase; Naphthoquinones; Oligonucleotides; Spin Labels | 1991 |
Resistance of paraquat and adriamycin in human breast tumor cells: role of free radical formation.
Topics: Breast Neoplasms; Chromium; Daunorubicin; DNA; Doxorubicin; Drug Resistance; Female; Humans; Hydroxides; Hydroxyl Radical; Paraquat; Tumor Cells, Cultured | 1989 |
Photochemistry of aqueous adriamycin and daunomycin. A spin trapping study with 17O enriched oxygen and water.
Topics: Daunorubicin; Doxorubicin; Electron Spin Resonance Spectroscopy; Hydroxides; Hydroxyl Radical; Oxygen Isotopes; Photochemistry; Water | 1988 |
Thiol-dependent DNA damage produced by anthracycline-iron complexes. The structure-activity relationships and molecular mechanisms.
Topics: Animals; Cattle; Daunorubicin; DNA; Dose-Response Relationship, Drug; Doxorubicin; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Iron; Oxygen Consumption; Spectrophotometry; Structure-Activity Relationship | 1985 |
Redox cycling of anthracyclines by cardiac mitochondria. II. Formation of superoxide anion, hydrogen peroxide, and hydroxyl radical.
Topics: Animals; Anthraquinones; Antibiotics, Antineoplastic; Cattle; Chemical Phenomena; Chemistry; Daunorubicin; Doxorubicin; Electron Spin Resonance Spectroscopy; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Methane; Mitochondria, Heart; Mitomycin; Mitomycins; Mitoxantrone; NAD; NADP; Naphthacenes; Oxidation-Reduction; Oxygen Consumption; Rotenone; Superoxides | 1986 |
Degradation of DNA by metalloanthracyclines: requirement for metal ions.
Topics: Acetates; Acetic Acid; Benzoates; Benzoic Acid; Catalase; Chemical Phenomena; Chemistry; Copper; Daunorubicin; DNA; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Mercaptoethanol; Oxygen; Poly dA-dT; Superoxide Dismutase | 1986 |
Doxorubicin enhances complement susceptibility of human melanoma cells by extracellular oxygen radical formation.
Topics: Catalase; Complement System Proteins; Daunorubicin; Doxorubicin; Free Radicals; Glutathione; Glutathione Disulfide; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Immunity, Cellular; Melanoma; Superoxide Dismutase; Superoxides | 1987 |
5-Iminodaunomycin. An anthracycline with unique properties.
Topics: Chemical Phenomena; Chemistry, Physical; Cyclic N-Oxides; Daunorubicin; DNA, Superhelical; DNA, Viral; Doxorubicin; Electron Spin Resonance Spectroscopy; Ferric Compounds; Hydrogen-Ion Concentration; Hydroxides; Hydroxyl Radical; Nitroso Compounds; Simian virus 40 | 1987 |
Oxygen radicals generation and DNA scission by anticancer and synthetic quinones.
Topics: Antineoplastic Agents; Cyclic N-Oxides; Daunorubicin; DNA Damage; Doxorubicin; Electron Spin Resonance Spectroscopy; Hydroxyl Radical; Kinetics; Mitomycin; Molecular Structure; NAD; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Quinones; Spectrophotometry, Ultraviolet; Spin Labels; Superoxides | 1994 |
Involvement of hydrogen peroxide and hydroxyl radical in chemically induced apoptosis of HL-60 cells.
Topics: Antineoplastic Agents; Apoptosis; Cisplatin; Cytarabine; Dactinomycin; Daunorubicin; HL-60 Cells; Humans; Hydrogen Peroxide; Hydroxyl Radical; Reactive Oxygen Species | 1999 |
Hydrogen peroxide and hydroxyl radical involvement in the activation of caspase-3 in chemically induced apoptosis of HL-60 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Apoptosis; Caspase 3; Caspases; Dactinomycin; Daunorubicin; Enzyme Activation; Enzyme Inhibitors; HL-60 Cells; Humans; Hydrogen Peroxide; Hydroxyl Radical; Nucleic Acid Synthesis Inhibitors | 2001 |
Sequence selective binding of bis-daunorubicin WP631 to DNA.
Topics: Antibiotics, Antineoplastic; Base Sequence; Binding Sites; Daunorubicin; Diethyl Pyrocarbonate; DNA; DNA Footprinting; Hydroxyl Radical; Molecular Structure; Potassium Permanganate | 2004 |