Compounds > hydroxyl radical
Page last updated: 2024-09-04

hydroxyl radical and dactinomycin

hydroxyl radical has been researched along with dactinomycin in 5 studies

Compound Research Comparison

Studies
(hydroxyl radical)		Trials
(hydroxyl radical)		Recent Studies (post-2010)
(hydroxyl radical)		Studies
(dactinomycin)		Trials
(dactinomycin)		Recent Studies (post-2010) (dactinomycin)
10,147263,65719,045355969

Protein Interaction Comparison

ProteinTaxonomyhydroxyl radical (IC50)dactinomycin (IC50)
RAD51Homo sapiens (human)32.1
Growth factor receptor-bound protein 2Homo sapiens (human)5
Discoidin domain-containing receptor 2Homo sapiens (human)9
Growth factor receptor-bound protein 2 Mus musculus (house mouse)5

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Churchill, ME; Hayes, JJ; Tullius, TD1
Eguchi, H; Koh, YH; Park, YS; Suzuki, K; Taniguchi, N1
Ikeda, K; Kajiwara, K; Kishida, E; Kojo, S; Masuzawa, Y; Tanabe, E; Tokumaru, S1
Haddad, JJ; Kanaan, SA; Land, SC; Saadé, NE; Safieh-Garabedian, B1
Hashimoto, R; Ikeda, K; Kajiwara, K; Kojo, S; Kuroi, R; Tokumaru, S1

Other Studies

5 other study(ies) available for hydroxyl radical and dactinomycin

ArticleYear
Detection of drug binding to DNA by hydroxyl radical footprinting. Relationship of distamycin binding sites to DNA structure and positioned nucleosomes on 5S RNA genes of Xenopus.
    Biochemistry, 1990, Jun-26, Volume: 29, Issue:25

    Topics: Animals; Base Composition; Base Sequence; Binding Sites; Cytosine; Dactinomycin; Distamycins; DNA; Edetic Acid; Guanine; Hydroxides; Hydroxyl Radical; Kinetics; Methods; Molecular Sequence Data; Nucleic Acid Conformation; Nucleosomes; RNA, Ribosomal; RNA, Ribosomal, 5S; Xenopus

1990
Acceleration of adhesion of cancer cells and neutrophils to endothelial cells in the absence of de novo protein synthesis: possible implication for involvement of hydroxyl radicals.
    Biochemical and biophysical research communications, 1999, Apr-02, Volume: 257, Issue:1

    Topics: Catalase; Cell Adhesion; Cell Membrane; Chelating Agents; Colonic Neoplasms; Cycloheximide; Dactinomycin; Edetic Acid; Endothelium, Vascular; Humans; Hydrogen Peroxide; Hydroxyl Radical; Hypoxanthine; Neutrophils; Nitrates; Protein Biosynthesis; Reactive Oxygen Species; Superoxide Dismutase; Tumor Cells, Cultured; Xanthine Oxidase

1999
Involvement of hydrogen peroxide and hydroxyl radical in chemically induced apoptosis of HL-60 cells.
    Biochemical pharmacology, 1999, Jun-15, Volume: 57, Issue:12

    Topics: Antineoplastic Agents; Apoptosis; Cisplatin; Cytarabine; Dactinomycin; Daunorubicin; HL-60 Cells; Humans; Hydrogen Peroxide; Hydroxyl Radical; Reactive Oxygen Species

1999
Chemioxyexcitation (delta pO2/ROS)-dependent release of IL-1 beta, IL-6 and TNF-alpha: evidence of cytokines as oxygen-sensitive mediators in the alveolar epithelium.
    Cytokine, 2001, Feb-07, Volume: 13, Issue:3

    Topics: Animals; Antioxidants; Catalase; Cells, Cultured; Cycloheximide; Cytokines; Dactinomycin; Female; Hydrogen Peroxide; Hydroxyl Radical; Interleukin-1; Interleukin-6; Mice; Oxidative Stress; Oxygen; Pulmonary Alveoli; Rats; Reactive Oxygen Species; Respiratory Mucosa; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2001
Hydrogen peroxide and hydroxyl radical involvement in the activation of caspase-3 in chemically induced apoptosis of HL-60 cells.
    Cellular and molecular life sciences : CMLS, 2001, Volume: 58, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Apoptosis; Caspase 3; Caspases; Dactinomycin; Daunorubicin; Enzyme Activation; Enzyme Inhibitors; HL-60 Cells; Humans; Hydrogen Peroxide; Hydroxyl Radical; Nucleic Acid Synthesis Inhibitors

2001