Page last updated: 2024-09-04

hydroxyl radical and cyclic gmp

hydroxyl radical has been researched along with cyclic gmp in 14 studies

Compound Research Comparison

Studies
(hydroxyl radical)
Trials
(hydroxyl radical)
Recent Studies (post-2010)
(hydroxyl radical)
Studies
(cyclic gmp)
Trials
(cyclic gmp)
Recent Studies (post-2010) (cyclic gmp)
10,147263,65722,3463334,062

Protein Interaction Comparison

ProteinTaxonomyhydroxyl radical (IC50)cyclic gmp (IC50)
Phosphodiesterase Bos taurus (cattle)0.1
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)2.4
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)2.4

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (57.14)18.2507
2000's4 (28.57)29.6817
2010's2 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Munkres, KD1
DeCampli, WM; Obayashi, DY; Wanna, FS; Young, JN1
Norisue, M; Okabe, E; Todoki, K1
Kaminski, PM; Wolin, MS; Xie, YW1
Cutler, RG; Kazama, S; Saito, K; Yoshioka, H1
Bassenge, E; Dikalov, S; Fink, B; Skatchkov, M; Stalleicken, D1
Altura, BM; Altura, BT; Yang, ZW; Zhang, A1
Chesnais, JM; Fischmeister, R; Mery, PF1
Dahlem, G; Ermert, L; Fink, L; Ghofrani, A; Grimminger, F; Guthmann, B; Haenze, J; König, P; Kummer, W; Rose, F; Seeger, W; Tenenbaum, T; Weissmann, N1
Allona, A; Angulo, J; Cuevas, P; Fernández, A; Gabancho, S; Martín-Morales, A; Moncada, I; Sáenz de Tejada, I1
Albrecht, J; Anderzhanova, E; Hilgier, W; Oja, SS; Saransaari, P1
Bast, A; de Vente, J; Haenen, GR; Rietjens, SJ1
Chen, WF; Chou, DS; Hou, SY; Hsiao, G; Jayakumar, T; Lee, JJ; Lee, YM; Sheu, JR1
Chou, DS; Hsiao, G; Hsu, MJ; Lin, KH; Lu, WJ; Sheu, JR1

Other Studies

14 other study(ies) available for hydroxyl radical and cyclic gmp

ArticleYear
Pharmacogenetics of cyclic guanylate, antioxidants, and antioxidant enzymes in Neurospora.
    Free radical biology & medicine, 1990, Volume: 9, Issue:1

    Topics: Aging; Antioxidants; Cell Differentiation; Culture Media; Cyclic GMP; Free Radicals; Gene Expression Regulation, Enzymologic; Hydroxides; Hydroxyl Radical; Mutation; Neurospora; Second Messenger Systems; Superoxide Dismutase; Theophylline

1990
Simultaneous manipulation of the nitric oxide and prostanoid pathways reduces myocardial reperfusion injury.
    The Journal of thoracic and cardiovascular surgery, 1995, Volume: 110, Issue:4 Pt 1

    Topics: Animals; Arginine; Aspirin; Cardioplegic Solutions; Coronary Circulation; Cyclic GMP; Glucose; Heart; Heart Rate; Hydroxyl Radical; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Rats; Rats, Sprague-Dawley; Tromethamine; Vascular Resistance

1995
Inhibition by hydroxyl radicals of calcitonin gene-related peptide-mediated neurogenic vasorelaxation in isolated canine lingual artery.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:1

    Topics: Animals; Benzopyrans; Calcitonin Gene-Related Peptide; Cromakalim; Cyclic GMP; Dogs; Female; Humans; Hydroxyl Radical; In Vitro Techniques; Male; Potassium Channels; Pyrroles; Vasodilation

1997
Inhibition of rat cardiac muscle contraction and mitochondrial respiration by endogenous peroxynitrite formation during posthypoxic reoxygenation.
    Circulation research, 1998, May-04, Volume: 82, Issue:8

    Topics: Animals; Bradykinin; Cyclic GMP; Free Radical Scavengers; Hydroxyl Radical; Hypoxia; In Vitro Techniques; Kinetics; Mannitol; Mitochondria, Heart; Myocardial Contraction; Nitrates; Nitric Oxide; Nitroarginine; Oxidants; Oxygen Consumption; Penicillamine; Rats; S-Nitroso-N-Acetylpenicillamine; Sodium Cyanide; Superoxide Dismutase

1998
Release of nitric oxide from a spin trap, N-tert-butyl-alpha-phenylnitrone, under various oxidative conditions.
    Biological & pharmaceutical bulletin, 1998, Volume: 21, Issue:4

    Topics: Animals; Cyclic GMP; Cyclic N-Oxides; Enzyme Inhibitors; Free Radical Scavengers; Free Radicals; Guanylate Cyclase; Hydroxyl Radical; In Vitro Techniques; Liver; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitrogen Oxides; Oxidation-Reduction; Spectrophotometry, Ultraviolet; Spin Trapping

1998
Formation of reactive oxygen species by pentaerithrityltetranitrate and glyceryl trinitrate in vitro and development of nitrate tolerance.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:2

    Topics: Animals; Blood Platelets; Cells, Cultured; Cyclic GMP; Drug Tolerance; Endothelium, Vascular; Hydroxyl Radical; Muscle, Smooth, Vascular; Nitrates; Nitroglycerin; Pentaerythritol Tetranitrate; Reactive Oxygen Species; Spin Trapping; Superoxides; Swine

1998
Endothelium-dependent relaxation to hydrogen peroxide in canine basilar artery: a potential new cerebral dilator mechanism.
    Brain research bulletin, 1998, Volume: 47, Issue:3

    Topics: Acetylcholine; Animals; Basilar Artery; Calcium; Cyclic GMP; Dogs; Endothelium, Vascular; Ferrous Compounds; Hydrogen Peroxide; Hydroxyl Radical; In Vitro Techniques; Intracellular Membranes; Male; Nitric Oxide; Osmolar Concentration; Vasodilation

1998
Peroxynitrite is a positive inotropic agent in atrial and ventricular fibres of the frog heart.
    The Journal of physiology, 1999, Dec-01, Volume: 521 Pt 2

    Topics: Aminoquinolines; Animals; Atrial Function; Catalase; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Heart Atria; Heart Ventricles; Hydroxyl Radical; Molsidomine; Muscle Fibers, Skeletal; Myocardial Contraction; Myocardium; Nitrates; Nitric Oxide Donors; Oxadiazoles; Oxidants; Quinoxalines; Rana esculenta; Sodium; Sodium-Calcium Exchanger; Ventricular Function

1999
Apical, but not basolateral, endotoxin preincubation protects alveolar epithelial cells against hydrogen peroxide-induced loss of barrier function: the role of nitric oxide synthesis.
    Journal of immunology (Baltimore, Md. : 1950), 2002, Aug-01, Volume: 169, Issue:3

    Topics: Animals; Cyclic GMP; Epithelial Cells; Hydrogen Peroxide; Hydroxyl Radical; Lipopolysaccharides; Male; Nitric Oxide; Nitric Oxide Synthase; Permeability; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; RNA, Messenger; Superoxides

2002
Activation and potentiation of the NO/cGMP pathway by NG-hydroxyl-L-arginine in rabbit corpus cavernosum under normoxic and hypoxic conditions and ageing.
    British journal of pharmacology, 2003, Volume: 138, Issue:1

    Topics: Aging; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Hydroxyl Radical; Hypoxia; In Vitro Techniques; Male; Nitric Oxide; Penis; Rabbits; Vasodilation

2003
Taurine reduces ammonia- and N-methyl-D-aspartate-induced accumulation of cyclic GMP and hydroxyl radicals in microdialysates of the rat striatum.
    European journal of pharmacology, 2003, May-02, Volume: 468, Issue:1

    Topics: Ammonium Chloride; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Cyclic GMP; Hydroxyl Radical; Male; Microdialysis; N-Methylaspartate; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Taurine

2003
The olive oil antioxidant hydroxytyrosol efficiently protects against the oxidative stress-induced impairment of the NObullet response of isolated rat aorta.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 292, Issue:4

    Topics: Animals; Antioxidants; Aorta; Benzene Derivatives; Cyclic GMP; Diet, Mediterranean; Free Radical Scavengers; Hydroxyl Radical; In Vitro Techniques; Male; Olive Oil; Oxidants; Oxidative Stress; Phenylethyl Alcohol; Plant Oils; Rats; Rats, Inbred Lew

2007
Cyclic nucleotides and mitogen-activated protein kinases: regulation of simvastatin in platelet activation.
    Journal of biomedical science, 2010, Jun-04, Volume: 17

    Topics: Calcium Signaling; Cell Adhesion Molecules; Collagen; Cyclic AMP; Cyclic GMP; Humans; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; MAP Kinase Signaling System; Microfilament Proteins; Mitogen-Activated Protein Kinase Kinases; Nitric Oxide; Nitric Oxide Synthase Type III; Nucleotides, Cyclic; Phospholipase C gamma; Phosphoproteins; Platelet Activation; Platelet Aggregation Inhibitors; Protein Kinase C; Signal Transduction; Simvastatin; Thromboxane A2

2010
Suppression of NF-κB signaling by andrographolide with a novel mechanism in human platelets: regulatory roles of the p38 MAPK-hydroxyl radical-ERK2 cascade.
    Biochemical pharmacology, 2012, Oct-01, Volume: 84, Issue:7

    Topics: Blood Platelets; Collagen; Cyclic GMP; Diterpenes; eIF-2 Kinase; Gene Expression Regulation; Humans; Hydroxyl Radical; I-kappa B Kinase; Mitogen-Activated Protein Kinase 1; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Platelet Activation; Platelet Aggregation Inhibitors; Signal Transduction

2012