hydroxyl radical has been researched along with chloroquine in 4 studies
| Studies (hydroxyl radical) | Trials (hydroxyl radical) | Recent Studies (post-2010) (hydroxyl radical) | Studies (chloroquine) | Trials (chloroquine) | Recent Studies (post-2010) (chloroquine) |
|---|---|---|---|---|---|
| 10,147 | 26 | 3,657 | 16,405 | 763 | 4,029 |
| Protein | Taxonomy | hydroxyl radical (IC50) | chloroquine (IC50) |
|---|---|---|---|
| glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | Plasmodium berghei | 43 | |
| Spike glycoprotein | Betacoronavirus England 1 | 5.47 | |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | 5.47 | |
| Transmembrane protease serine 2 | Homo sapiens (human) | 5.47 | |
| Dihydrofolate reductase | Bos taurus (cattle) | 0.0301 | |
| Amyloid-beta precursor protein | Homo sapiens (human) | 7 | |
| Histidine-rich protein PFHRP-II | Plasmodium falciparum (malaria parasite P. falciparum) | 0.2383 | |
| Procathepsin L | Homo sapiens (human) | 5.47 | |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | 5.47 | |
| Replicase polyprotein 1ab | Human coronavirus 229E | 5.47 | |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | 5.47 | |
| Spike glycoprotein | Severe acute respiratory syndrome coronavirus 2 | 3.58 | |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | 6.375 | |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | 1.5 | |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | 0.27 | |
| Beta-secretase 1 | Homo sapiens (human) | 7 | |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | 5.47 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 2.503 | |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | 6.235 | |
| Cysteine proteinase falcipain 2a | Plasmodium falciparum (malaria parasite P. falciparum) | 0.02 | |
| Cysteine proteinase falcipain 2a | Plasmodium falciparum (malaria parasite P. falciparum) | 0.2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maeda, M; Neda, H; Niitsu, Y; Sone, H; Urushizaki, I; Watanabe, N; Yamauchi, N | 1 |
| Ginsburg, H; Golenser, J | 1 |
| Alumasa, JN; Casabianca, LB; Comstock, E; de Dios, AC; Gorka, AP; Roepe, PD | 1 |
| Chen, Y; Ding, L; Shi, J; Yang, B; Yao, H | 1 |
1 review(s) available for hydroxyl radical and chloroquine
| Article | Year |
|---|---|
Redox metabolism in glucose-6-phosphate dehydrogenase deficient erythrocytes and its relation to antimalarial chemotherapy.
Topics: Animals; Antimalarials; Cells, Cultured; Chloroquine; Erythrocytes; Glucosephosphate Dehydrogenase Deficiency; Glutathione; Humans; Hydroxyl Radical; Malaria, Falciparum; Oxidation-Reduction; Plasmodium falciparum | 1999 |
3 other study(ies) available for hydroxyl radical and chloroquine
| Article | Year |
|---|---|
Cytocidal mechanism of TNF: effects of lysosomal enzyme and hydroxyl radical inhibitors on cytotoxicity.
Topics: Ammonium Chloride; Animals; Chloroquine; Cytotoxicity, Immunologic; Dimethyl Sulfoxide; Free Radicals; Hydroxides; Hydroxyl Radical; Leupeptins; Masoprocol; Methylamines; Mice; Muramidase; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1988 |
The hydroxyl functionality and a rigid proximal N are required for forming a novel non-covalent quinine-heme complex.
Topics: Amodiaquine; Antimalarials; Chloroquine; Dimerization; Dose-Response Relationship, Drug; Hemeproteins; Hemin; Hydroxyl Radical; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Malaria, Falciparum; Nitrogen; Plasmodium falciparum; Quinine | 2011 |
A Metal-Organic Framework (MOF) Fenton Nanoagent-Enabled Nanocatalytic Cancer Therapy in Synergy with Autophagy Inhibition.
Topics: Animals; Apoptosis; Autophagy; Catalysis; Cell Line, Tumor; Chloroquine; Drug Synergism; Female; Humans; Hydrogen Peroxide; Hydroxyl Radical; Iron; Kaplan-Meier Estimate; Metal-Organic Frameworks; Mice; Mice, Nude; Neoplasms; Oxidative Stress; Transplantation, Heterologous | 2020 |