Compounds > hydroxyl radical
Page last updated: 2024-09-04

hydroxyl radical and carvedilol

hydroxyl radical has been researched along with carvedilol in 4 studies

Compound Research Comparison

Studies
(hydroxyl radical)		Trials
(hydroxyl radical)		Recent Studies (post-2010)
(hydroxyl radical)		Studies
(carvedilol)		Trials
(carvedilol)		Recent Studies (post-2010) (carvedilol)
10,147263,6572,9336801,052

Protein Interaction Comparison

ProteinTaxonomyhydroxyl radical (IC50)carvedilol (IC50)
Solute carrier family 22 member 2Homo sapiens (human)7.5
Solute carrier family 22 member 1 Homo sapiens (human)3.4
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.115
Potassium channel subfamily K member 2Homo sapiens (human)1.6
Beta-2 adrenergic receptorHomo sapiens (human)0.0002
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)0.538
ATP-dependent translocase ABCB1Homo sapiens (human)5.7333
Beta-1 adrenergic receptorHomo sapiens (human)0.0002
Alpha-2A adrenergic receptorHomo sapiens (human)0.106
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)4.1193
Beta-3 adrenergic receptorHomo sapiens (human)0.0042
D(2) dopamine receptorHomo sapiens (human)0.146
Alpha-2B adrenergic receptorHomo sapiens (human)0.094
Alpha-2C adrenergic receptorHomo sapiens (human)0.09
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.0058
D(1A) dopamine receptorHomo sapiens (human)1.498
Sodium-dependent noradrenaline transporter Homo sapiens (human)0.538
Alpha-1D adrenergic receptorHomo sapiens (human)0.0018
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.41
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.115
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.0058
Sodium-dependent serotonin transporterHomo sapiens (human)0.221
D(3) dopamine receptorHomo sapiens (human)0.577
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.023
5-hydroxytryptamine receptor 6Homo sapiens (human)1.519
Potassium channel subfamily K member 10Homo sapiens (human)7.6
Sodium-dependent dopamine transporter Homo sapiens (human)0.845
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)2.2346
Cytochrome P450 1B1Homo sapiens (human)1.1
Nuclear receptor subfamily 3 group C member 3 Bos taurus (cattle)4.1193

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Feuerstein, R; Yue, TL1
Kramer, JH; Weglicki, WB1
Franconi, F; Tadolini, B1
Bäumer, AT; Böhm, M; Cremers, B; Flesch, M; Maack, C; Südkamp, M1

Other Studies

4 other study(ies) available for hydroxyl radical and carvedilol

ArticleYear
A potent antioxidant, SB209995, inhibits oxygen-radical-mediated lipid peroxidation and cytotoxicity.
    Pharmacology, 1994, Volume: 48, Issue:6

    Topics: Animals; Antioxidants; Brain; Carbazoles; Carvedilol; Cattle; Cells, Cultured; Endothelium, Vascular; Free Radicals; Humans; Hydroxyl Radical; Lipid Peroxidation; Lipoproteins, LDL; Oxygen; Propanolamines; Rats; Superoxides; Xanthine Oxidase

1994
A hydroxylated analog of the beta-adrenoceptor antagonist, carvedilol, affords exceptional antioxidant protection to postischemic rat hearts.
    Free radical biology & medicine, 1996, Volume: 21, Issue:6

    Topics: Adrenergic beta-Antagonists; Alcohols; Animals; Antioxidants; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Hemodynamics; Hydroxyl Radical; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Myocardial Reperfusion Injury; Propanolamines; Rats; Rats, Sprague-Dawley

1996
Carvedilol inhibition of lipid peroxidation. A new antioxidative mechanism.
    Free radical research, 1998, Volume: 29, Issue:5

    Topics: Antioxidants; Carbazoles; Carvedilol; Chlorides; Ferric Compounds; Ferrous Compounds; Free Radical Scavengers; Hydroxyl Radical; Kinetics; Lipid Peroxidation; Lipid Peroxides; Liposomes; Oxidation-Reduction; Oxygen Consumption; Phosphatidylcholines; Propanolamines; Sonication; Superoxides

1998
Effect of beta-blockers on free radical-induced cardiac contractile dysfunction.
    Circulation, 1999, Jul-27, Volume: 100, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Calcium; Calcium-Transporting ATPases; Carbazoles; Carvedilol; Electric Stimulation; Female; Humans; Hydroxyl Radical; In Vitro Techniques; Male; Metoprolol; Middle Aged; Myocardial Contraction; Propanolamines; Receptors, Adrenergic, beta; Sarcoplasmic Reticulum

1999