Page last updated: 2024-09-04

hydroxyl radical and caffeine

hydroxyl radical has been researched along with caffeine in 25 studies

Compound Research Comparison

Studies
(hydroxyl radical)
Trials
(hydroxyl radical)
Recent Studies (post-2010)
(hydroxyl radical)
Studies
(caffeine)
Trials
(caffeine)
Recent Studies (post-2010) (caffeine)
10,147263,65725,5012,3936,825

Protein Interaction Comparison

ProteinTaxonomyhydroxyl radical (IC50)caffeine (IC50)
AcetylcholinesteraseHomo sapiens (human)7.25

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.00)18.7374
1990's5 (20.00)18.2507
2000's6 (24.00)29.6817
2010's11 (44.00)24.3611
2020's2 (8.00)2.80

Authors

AuthorsStudies
Dalal, NS; Jain, AC; Shi, X1
Powers, EL1
Okabe, E; Sasaki, H1
Devasagayam, TP; Kamat, JP; Kesavan, PC; Mohan, H1
Fay, LB; Richoz, J; Stadler, RH; Turesky, RJ; Welti, DH1
Okabe, E; Wada, S1
Tamura, K; Wada-Takahashi, S1
Lin, JK; Lin, YS; Wu, SS1
Lin, JK; Lin, YS; Tsai, YJ; Tsay, JS1
Azam, S; Hadi, N; Hadi, SM; Khan, NU1
Fujita, S; Hara, Y; Ishizuka, M; Kazusaka, A; Maeda, Y; Nikaidou, S1
He, P; Jie, G; Tu, Y; Xu, Y; Yang, Z1
Hegde, KR; Varma, SD1
Dziubina, A; Gołembiowska, K2
Barreca, D; Bellocco, E; De Rosa, MC; Ficarra, S; Galtieri, A; Giardina, B; Laganà, G; Leuzzi, U; Pirolli, D; Russo, A; Tellone, E1
Chin, YP; Houtz, EF; Jacobs, LE; Weavers, LK1
Bai, QQ; Di, DL; Guo, M; Liu, YF; Zhang, TC; Zhao, JX1
Górska, A; Gołembiowska, K; Kamińska, K; Noworyta-Sokołowska, K; Wardas, J1
Ambrosi, P; Behr, GA; da Rocha, JB; Gelain, DP; Kolling, EA; Moreira, JC; Pires, AS; Rybarczyk-Filho, JL; Terra, SR; Zeidán-Chuliá, F1
Górska, AM; Gołembiowska, K; Noworyta-Sokołowska, K1
Ergul, B; Zhao, EH; Zhao, W1
Chen, L; Fang, J; Guo, K; Hou, S; Kong, X; Meng, F; Shang, C; Wu, Z; Xiao, H; Yang, X1
Kim, SH; Lee, MH; Tanaka, M; Watanabe, T1
Li, J; Liu, H; Meng, Y; Wang, X; Zhang, T1

Other Studies

25 other study(ies) available for hydroxyl radical and caffeine

ArticleYear
Antioxidant behaviour of caffeine: efficient scavenging of hydroxyl radicals.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1991, Volume: 29, Issue:1

    Topics: Antioxidants; Caffeine; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Ethanol; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Iron; NADP

1991
Purine and its analogues and radiation damage in Bacillus megaterium spores.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1986, Volume: 50, Issue:6

    Topics: Bacillus megaterium; Caffeine; DNA; Hydroxides; Hydroxyl Radical; Oxygen; Purines; Radiation Tolerance; Spores, Bacterial

1986
Modification by hydroxyl radicals of functional reactivity in rabbit lingual artery.
    Japanese journal of pharmacology, 1993, Volume: 62, Issue:3

    Topics: Animals; Arteries; Caffeine; Endothelium, Vascular; Ferric Compounds; Ferrous Compounds; Fumarates; Hydrogen Peroxide; Hydroxyl Radical; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nisoldipine; Norepinephrine; Rabbits; Sarcoplasmic Reticulum; Tongue; Vasodilator Agents

1993
Caffeine as an antioxidant: inhibition of lipid peroxidation induced by reactive oxygen species.
    Biochimica et biophysica acta, 1996, Jun-13, Volume: 1282, Issue:1

    Topics: Animals; Antioxidants; Ascorbic Acid; Caffeine; Female; Glutathione; Hydroxyl Radical; Lipid Peroxidation; Microsomes, Liver; Oxygen; Peroxides; Rats; Rats, Wistar; Reactive Oxygen Species; Singlet Oxygen; Thiobarbituric Acid Reactive Substances

1996
Oxidation of caffeine and related methylxanthines in ascorbate and polyphenol-driven Fenton-type oxidations.
    Free radical research, 1996, Volume: 24, Issue:3

    Topics: Animals; Ascorbic Acid; Caffeine; Catalase; Cattle; Chromatography, High Pressure Liquid; Edetic Acid; Ferrous Compounds; Hydroxyl Radical; Kinetics; Liver; Mass Spectrometry; Molecular Structure; Oxidation-Reduction; Phenols; Purines; Superoxide Dismutase; Xanthine; Xanthine Oxidase; Xanthines

1996
Susceptibility of caffeine- and Ins(1,4,5)P3-induced contractions to oxidants in permeabilized vascular smooth muscle.
    European journal of pharmacology, 1997, Feb-05, Volume: 320, Issue:1

    Topics: Animals; Caffeine; Calcium; Hydrogen Peroxide; Hydroxyl Radical; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Permeability; Rabbits; Reactive Oxygen Species; Superoxides; Type C Phospholipases; Vasoconstrictor Agents

1997
Actions of reactive oxygen species on AH/type 2 myenteric neurons in guinea pig distal colon.
    American journal of physiology. Gastrointestinal and liver physiology, 2000, Volume: 279, Issue:5

    Topics: Action Potentials; Animals; Caffeine; Colon; Guinea Pigs; Hydrogen Peroxide; Hydroxyl Radical; Hypoxanthine; Male; Myenteric Plexus; Neurons; Oxidants; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Reactive Oxygen Species; Xanthine Oxidase

2000
Determination of tea polyphenols and caffeine in tea flowers (Camellia sinensis) and their hydroxyl radical scavenging and nitric oxide suppressing effects.
    Journal of agricultural and food chemistry, 2003, Feb-12, Volume: 51, Issue:4

    Topics: Apoptosis; Caffeine; Camellia sinensis; Chromatography, High Pressure Liquid; Flavonoids; Flowers; Free Radical Scavengers; Hydroxyl Radical; Lipopolysaccharides; Nitric Oxide; Phenols; Plant Extracts; Polymers; Polyphenols

2003
Factors affecting the levels of tea polyphenols and caffeine in tea leaves.
    Journal of agricultural and food chemistry, 2003, Mar-26, Volume: 51, Issue:7

    Topics: Caffeine; Camellia sinensis; Catechin; Chromatography, High Pressure Liquid; Flavonoids; Free Radical Scavengers; Hot Temperature; Hydroxyl Radical; Phenols; Plant Extracts; Plant Leaves; Polymers; Tea

2003
Antioxidant and prooxidant properties of caffeine, theobromine and xanthine.
    Medical science monitor : international medical journal of experimental and clinical research, 2003, Volume: 9, Issue:9

    Topics: Animals; Antioxidants; Caffeine; Cattle; Copper; DNA; DNA Damage; Hydroxyl Radical; Oxidants; Plasmids; Theobromine; Uric Acid; Xanthine

2003
Effect of catechins on mutagenesis of Salmonella typhimurium TA 102 elicited by tert-butyl hydroperoxide (t-BuOOH).
    The Journal of veterinary medical science, 2005, Volume: 67, Issue:1

    Topics: Animals; Antimutagenic Agents; Caffeine; Catechin; Free Radical Scavengers; Hydroxyl Radical; Male; Mutagenicity Tests; Rats; Rats, Wistar; Salmonella typhimurium; Tea; tert-Butylhydroperoxide

2005
Study on the antioxidant activity of tea flowers (Camellia sinensis).
    Asia Pacific journal of clinical nutrition, 2007, Volume: 16 Suppl 1

    Topics: Antioxidants; Biphenyl Compounds; Caffeine; Catechin; Flowers; Food Technology; Free Radical Scavengers; Hydroxyl Radical; Oxidation-Reduction; Picrates; Plant Extracts; Tea

2007
Prevention of oxidative damage to lens by caffeine.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2010, Volume: 26, Issue:1

    Topics: Adenosine Triphosphate; Animals; Antioxidants; Biological Transport; Caffeine; Cyclic N-Oxides; Free Radical Scavengers; Glutathione; Hydroxyl Radical; In Vitro Techniques; Iron Compounds; Lens, Crystalline; Mice; Mice, Inbred Strains; Oxidative Stress; Reactive Oxygen Species; Rubidium; Sodium-Potassium-Exchanging ATPase; Spin Labels

2010
Effect of adenosine A(2A) receptor antagonists and L-DOPA on hydroxyl radical, glutamate and dopamine in the striatum of 6-OHDA-treated rats.
    Neurotoxicity research, 2012, Volume: 21, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine A2 Receptor Antagonists; Animals; Benserazide; Caffeine; Dopamine; Glutamic Acid; Hydroxyl Radical; Levodopa; Male; Microdialysis; Neostriatum; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Receptor, Adenosine A2A; Triazines; Triazoles

2012
Caffeine inhibits erythrocyte membrane derangement by antioxidant activity and by blocking caspase 3 activation.
    Biochimie, 2012, Volume: 94, Issue:2

    Topics: Anion Exchange Protein 1, Erythrocyte; Binding Sites; Biological Transport; Caffeine; Caspase 3; Erythrocyte Membrane; Erythrocytes; Heme; Hemoglobins; Humans; Hydroxyl Radical; Kinetics; Models, Molecular; NADP; Oxidation-Reduction; Oxygen; Pentose Phosphate Pathway; Protein Binding; Protein Conformation; Thermodynamics

2012
Photosensitized degradation of caffeine: role of fulvic acids and nitrate.
    Chemosphere, 2012, Volume: 86, Issue:2

    Topics: Benzopyrans; Caffeine; Environmental Restoration and Remediation; Hydrogen-Ion Concentration; Hydroxyl Radical; Nitrates; Photolysis; Sunlight; Waste Disposal, Fluid

2012
[Study on extraction process of available components of tea].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2011, Volume: 34, Issue:9

    Topics: Antioxidants; Caffeine; Catechin; Ethanol; Hydroxyl Radical; Solvents; Tea; Technology, Pharmaceutical; Temperature; Time Factors

2011
The effect of adenosine A(2A) receptor antagonists on hydroxyl radical, dopamine, and glutamate in the striatum of rats with altered function of VMAT2.
    Neurotoxicity research, 2012, Volume: 22, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine A2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Animals; Caffeine; Corpus Striatum; Dopamine; Dopamine Agents; Extracellular Space; Glutamic Acid; Homovanillic Acid; Hydroxyl Radical; Levodopa; Male; Microdialysis; Oxidative Stress; Rats; Rats, Wistar; Reserpine; Triazines; Triazoles; Vesicular Monoamine Transport Proteins

2012
Effects of adenosine receptor antagonists on the in vivo LPS-induced inflammation model of Parkinson's disease.
    Neurotoxicity research, 2013, Volume: 24, Issue:1

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Caffeine; Corpus Striatum; Dopamine; Dopaminergic Neurons; Glutamic Acid; Hydroxyl Radical; Inflammation; Lipopolysaccharides; Male; Microinjections; Parkinson Disease; Purines; Rats; Receptor, Adenosine A2A

2013
Major components of energy drinks (caffeine, taurine, and guarana) exert cytotoxic effects on human neuronal SH-SY5Y cells by decreasing reactive oxygen species production.
    Oxidative medicine and cellular longevity, 2013, Volume: 2013

    Topics: Antioxidants; Caffeine; Catalase; Cell Count; Cell Death; Cell Line, Tumor; Cell Shape; Cell Survival; Energy Drinks; Free Radical Scavengers; Humans; Hydroxyl Radical; Intracellular Space; Lipid Metabolism; Models, Biological; Nerve Degeneration; Neurites; Neurons; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Paullinia; Reactive Oxygen Species; Superoxide Dismutase; Taurine

2013
The effect of caffeine on MDMA-induced hydroxyl radical production in the mouse striatum.
    Pharmacological reports : PR, 2014, Volume: 66, Issue:4

    Topics: Animals; Caffeine; Corpus Striatum; Dose-Response Relationship, Drug; Hydroxyl Radical; Male; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Neuroprotective Agents; Neurotoxicity Syndromes

2014
Caffeine's antioxidant potency optically sensed with double-stranded DNA-encased single-walled carbon nanotubes.
    The journal of physical chemistry. B, 2015, Mar-12, Volume: 119, Issue:10

    Topics: Antioxidants; Ascorbic Acid; Caffeine; DNA; Electron Spin Resonance Spectroscopy; Hydrogen Peroxide; Hydroxyl Radical; Nanotubes, Carbon; Reactive Oxygen Species; Uric Acid

2015
Factors affecting the roles of reactive species in the degradation of micropollutants by the UV/chlorine process.
    Water research, 2017, 12-01, Volume: 126

    Topics: Ammonia; Anti-Infective Agents; Bicarbonates; Caffeine; Chlorides; Chlorine; DEET; Free Radical Scavengers; Halogenation; Hydrogen-Ion Concentration; Hydroxyl Radical; Kinetics; Metronidazole; Nalidixic Acid; Oxidation-Reduction; Ultraviolet Rays; Water; Water Pollutants, Chemical; Water Purification

2017
Enhanced decomposition of caffeine by water plasma combined with mist generator: Effect of operational parameter and decomposition pathway.
    Chemosphere, 2022, Volume: 307, Issue:Pt 3

    Topics: Caffeine; Carbon; Carbon Dioxide; Gases; Hydroxyl Radical; Nitrates; Wastewater; Water

2022
Mechanistic insights into UV photolysis of carbamazepine and caffeine: Active species, reaction sites, and toxicity evolution.
    Chemosphere, 2022, Volume: 308, Issue:Pt 3

    Topics: Caffeine; Carbamazepine; Ecosystem; Humans; Humic Substances; Hydroxyl Radical; Oxidation-Reduction; Oxygen Isotopes; Pharmaceutical Preparations; Photolysis; Singlet Oxygen; Ultraviolet Rays; Water; Water Pollutants, Chemical; Water Purification

2022