hydroxyl radical has been researched along with aspirin in 19 studies
| Studies (hydroxyl radical) | Trials (hydroxyl radical) | Recent Studies (post-2010) (hydroxyl radical) | Studies (aspirin) | Trials (aspirin) | Recent Studies (post-2010) (aspirin) |
|---|---|---|---|---|---|
| 10,147 | 26 | 3,657 | 48,947 | 6,817 | 13,778 |
| Protein | Taxonomy | hydroxyl radical (IC50) | aspirin (IC50) |
|---|---|---|---|
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | 0.35 | |
| Integrin beta-3 | Homo sapiens (human) | 5 | |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 0.8252 | |
| Seed linoleate 13S-lipoxygenase-1 | Glycine max (soybean) | 1.375 | |
| Integrin alpha-IIb | Homo sapiens (human) | 5 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 2.271 | |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | 2.4 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 2.15 | |
| Urotensin-2 receptor | Rattus norvegicus (Norway rat) | 0.3 | |
| 4-aminobutyrate aminotransferase, mitochondrial | Rattus norvegicus (Norway rat) | 2.4 | |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | 0.35 | |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | 2.4081 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (10.53) | 18.7374 |
| 1990's | 10 (52.63) | 18.2507 |
| 2000's | 6 (31.58) | 29.6817 |
| 2010's | 1 (5.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cavallo, G; Chessa, MA; Milazzotto, F; Natale, E; Pensa, V; Ricci, R; Tubaro, E; Tubaro, M | 1 |
| DeMocko, C; Sagone, AL; Wells, RM | 1 |
| Bianchine, J; Greenwald, JE; Metz, EN; Sagone, AL; Singh, D | 1 |
| DeCampli, WM; Obayashi, DY; Wanna, FS; Young, JN | 1 |
| Coudray, C; Fatôme, M; Favier, A; Martin, S; Talla, M | 1 |
| Chandrakasan, G; Chithra, P; Lal, S | 1 |
| Böning, J; Davids, E; Foley, P; Gerlach, M; Riederer, P; Thome, J; Weijers, HG; Wiesbeck, GA; Zhang, J | 1 |
| Colavita, AR; FitzGerald, GA; Ghiselli, A; Iuliano, L; Leo, R; Pignatelli, P; Praticò, D; Pulcinelli, FM; Violi, F | 1 |
| Aprile, F; Frati, E; Front, P; Khatib, AM; Mitrovic, DR; Panasyuk, A | 1 |
| Aubin, N; Carter, C; Curet, O; Deffois, A | 1 |
| Barry, OP; FitzGerald, GA; Ghiselli, A; Iuliano, L; Pasin, M; Praticó, D; Sabatino, G; Violi, F | 1 |
| Castranova, V; Chen, F; Ding, M; Dong, Z; Leonard, SS; Shi, X; Vallyathan, V; Wang, S; Ye, J | 1 |
| Coudray, C; Favier, A | 1 |
| Chen, F; Flynn, DC; Jiang, BH; Leonard, SS; Qian, Y; Shi, X; Wang, L; Wang, S; Ye, J; Zhang, Z | 1 |
| Del Soldato, P; Felix, CC; Olds, CL; Pieper, GM; Siebeneich, W | 1 |
| Chang, CP; Huang, WT; Kao, TY; Lin, MT | 1 |
| Ito, N; Kashimoto, T; Nishimura, Y; Seki, T; Shiho, K; Sugiyama, M; Susa, N; Takeda-Homma, S; Ueno, S | 1 |
| Chen, W; Jia, Z; Li, J; Li, Y; Misra, HP; Zhou, K; Zhu, H | 1 |
| He, L; Ren, S; Sun, X; Wang, S; Zhu, F | 1 |
19 other study(ies) available for hydroxyl radical and aspirin
| Article | Year |
|---|---|
Demonstration of the formation of hydroxyl radicals in acute myocardial infarction in man using salicylate as probe.
Topics: Aspirin; Chromatography, High Pressure Liquid; Female; Free Radicals; Gentisates; Humans; Hydroxides; Hydroxybenzoates; Hydroxyl Radical; Isosorbide Dinitrate; Male; Middle Aged; Myocardial Infarction; Tissue Plasminogen Activator | 1992 |
Evidence that OH. production by human PMNs is related to prostaglandin metabolism.
Topics: Aspirin; Granulocytes; Humans; Hydrogen; Hydroxides; Hydroxyl Radical; Indomethacin; Neutrophils; Oxygen; Phagocytosis; Phenols; Prostaglandins; Zymosan | 1980 |
Evidence for the generation of hydroxyl radical during arachidonic acid metabolism by human platelets.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Carbon Dioxide; Cell Separation; Dimethyl Sulfoxide; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; Thromboxane B2; Time Factors | 1981 |
Simultaneous manipulation of the nitric oxide and prostanoid pathways reduces myocardial reperfusion injury.
Topics: Animals; Arginine; Aspirin; Cardioplegic Solutions; Coronary Circulation; Cyclic GMP; Glucose; Heart; Heart Rate; Hydroxyl Radical; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Rats; Rats, Sprague-Dawley; Tromethamine; Vascular Resistance | 1995 |
High-performance liquid chromatography-electrochemical determination of salicylate hydroxylation products as an in vivo marker of oxidative stress.
Topics: Adult; Aspirin; Calibration; Chromatography, High Pressure Liquid; Female; Free Radical Scavengers; Gentisates; Humans; Hydroxybenzoates; Hydroxyl Radical; Male; Oxidative Stress; Reproducibility of Results; Salicylates; Salicylic Acid; Thiobarbituric Acid Reactive Substances | 1995 |
The possible relevance of autoxidative glycosylation in glucose mediated alterations of proteins: an in vitro study on myofibrillar proteins.
Topics: Animals; Aspirin; Ca(2+) Mg(2+)-ATPase; Chlorides; Copper; Copper Sulfate; Edetic Acid; Ferric Compounds; Glucose; Glycosylation; Guanidines; Hydroxyl Radical; Kinetics; Male; Muscle Proteins; Myofibrils; Oxidation-Reduction; Rats | 1996 |
Evidence for increased oxidative stress in alcohol-dependent patients provided by quantification of in vivo salicylate hydroxylation products.
Topics: Adult; Alcoholism; Aspirin; Biotransformation; Female; Humans; Hydroxybenzoates; Hydroxyl Radical; Lipid Peroxidation; Male; Metabolic Clearance Rate; Middle Aged; Oxidative Stress; Reactive Oxygen Species | 1997 |
Platelet activation by superoxide anion and hydroxyl radicals intrinsically generated by platelets that had undergone anoxia and then reoxygenated.
Topics: Acridines; Aerobiosis; Aspirin; Benzoates; Blood Platelets; Catalase; Cell Hypoxia; Deoxyribose; Free Radical Scavengers; Humans; Hydroxyl Radical; In Vitro Techniques; Indomethacin; L-Lactate Dehydrogenase; Mannitol; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Superoxide Dismutase; Superoxides | 1997 |
Degradation of hyaluronic acid by photosensitized riboflavin in vitro. Modulation of the effect by transition metals, radical quenchers, and metal chelators.
Topics: Animals; Aspirin; Azides; Catalase; Cattle; Chelating Agents; Dimethyl Sulfoxide; Hyaluronic Acid; Hydrogen-Ion Concentration; Hydroxyl Radical; Mannitol; Metals; Oxygen; Reactive Oxygen Species; Riboflavin; Singlet Oxygen; Sodium Azide; Superoxide Dismutase; Synovial Fluid; Thiourea; Ultraviolet Rays; Viscosity | 1997 |
Aspirin and salicylate protect against MPTP-induced dopamine depletion in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Aspirin; Body Temperature; Corpus Striatum; Cyclooxygenase Inhibitors; Dexamethasone; Dopamine; Hydroxybenzoates; Hydroxyl Radical; Lysine; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase; MPTP Poisoning; Salicylates; Salicylic Acid; Serotonin; Synaptosomes | 1998 |
Iron-dependent human platelet activation and hydroxyl radical formation: involvement of protein kinase C.
Topics: Adult; Aspirin; Blood Platelets; Catalase; Chelating Agents; Collagen; Deferoxamine; Deoxyribose; Diuretics, Osmotic; Dose-Response Relationship, Drug; Edetic Acid; Enzyme Inhibitors; Female; Humans; Hydroxyl Radical; Indoles; Iron; Isoquinolines; Male; Maleimides; Mannitol; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Kinase C; Sulfonamides; Thromboxane A2; Thromboxane B2 | 1999 |
Antioxidant properties of aspirin: characterization of the ability of aspirin to inhibit silica-induced lipid peroxidation, DNA damage, NF-kappaB activation, and TNF-alpha production.
Topics: Animals; Antioxidants; Ascorbic Acid; Aspirin; Cells, Cultured; DNA Damage; Free Radical Scavengers; Hydroxyl Radical; Iron; Lipid Peroxidation; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Silicon Dioxide; Superoxides; Tumor Necrosis Factor-alpha | 1999 |
Determination of salicylate hydroxylation products as an in vivo oxidative stress marker.
Topics: Adult; Aspirin; Biomarkers; Chromatography, High Pressure Liquid; Humans; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Oxidative Stress; Salicylic Acid; Sensitivity and Specificity | 2000 |
Cr (VI) increases tyrosine phosphorylation through reactive oxygen species-mediated reactions.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Catalase; Cell Line; Chromium; Epithelial Cells; Formates; Hemostatics; Humans; Hydrogen Peroxide; Hydroxyl Radical; Lung; Phosphorylation; Protein-Tyrosine Kinases; Time Factors | 2001 |
Vascular protective actions of a nitric oxide aspirin analog in both in vitro and in vivo models of diabetes mellitus.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Aspirin; Diabetes Mellitus, Experimental; Electron Spin Resonance Spectroscopy; Electrophoretic Mobility Shift Assay; Endothelium, Vascular; Free Radical Scavengers; Gene Expression; Glucose; Hydroxyl Radical; Hyperglycemia; Isoprostanes; Muscle Relaxation; Muscle, Smooth, Vascular; NF-kappa B; Nitric Oxide; Norepinephrine; Rats; Rats, Sprague-Dawley; Superoxides; Vasodilation | 2002 |
Aspirin may exert its antipyresis by inhibiting the N-methyl-D-aspartate receptor-dependent hydroxyl radical pathways in the hypothalamus.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dinoprostone; Fever; Glutamic Acid; Hydroxyl Radical; Hypothalamus; Lipopolysaccharides; Male; Microdialysis; Rabbits; Receptors, N-Methyl-D-Aspartate; Stereotaxic Techniques | 2007 |
Estimation of hydroxyl radical generation by salicylate hydroxylation method in kidney of mice exposed to ferric nitrilotriacetate and potassium bromate.
Topics: Animals; Aspirin; Bromates; Comet Assay; DNA Adducts; DNA Damage; Ferric Compounds; Hydroxyl Radical; Hydroxylation; Kidney; Kidney Function Tests; Lipid Peroxidation; Male; Mice; Mice, Inbred ICR; Mixed Function Oxygenases; Nitrilotriacetic Acid; Salicylates | 2007 |
Inhibition of peroxynitrite-mediated DNA strand cleavage and hydroxyl radical formation by aspirin at pharmacologically relevant concentrations: implications for cancer intervention.
Topics: Anticarcinogenic Agents; Aspirin; Bacteriophage phi X 174; DNA Cleavage; Humans; Hydroxyl Radical; Molsidomine; Neoplasms; Peroxynitrous Acid; Plasmids | 2009 |
OH-initiated transformation and hydrolysis of aspirin in AOPs system: DFT and experimental studies.
Topics: Aspirin; Hydrogen Peroxide; Hydrolysis; Hydroxyl Radical; Kinetics; Oxidation-Reduction | 2017 |