hydroxyl radical has been researched along with ametantrone in 2 studies
| Studies (hydroxyl radical) | Trials (hydroxyl radical) | Recent Studies (post-2010) (hydroxyl radical) | Studies (ametantrone) | Trials (ametantrone) | Recent Studies (post-2010) (ametantrone) |
|---|---|---|---|---|---|
| 10,147 | 26 | 3,657 | 93 | 1 | 8 |
| Protein | Taxonomy | hydroxyl radical (IC50) | ametantrone (IC50) |
|---|---|---|---|
| DNA topoisomerase 2-beta | Homo sapiens (human) | 0.03 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fisher, GR; Gutierrez, PL; Oldcorne, MA; Patterson, LH | 1 |
| Kharasch, ED; Novak, RF | 1 |
2 other study(ies) available for hydroxyl radical and ametantrone
| Article | Year |
|---|---|
NAD(P)H (quinone acceptor) oxidoreductase (DT-diaphorase)-mediated two-electron reduction of anthraquinone-based antitumour agents and generation of hydroxyl radicals.
Topics: Animals; Anthraquinones; Antineoplastic Agents; Daunorubicin; Dose-Response Relationship, Drug; Hydroxides; Hydroxyl Radical; Kinetics; Liver; Mitoxantrone; NAD(P)H Dehydrogenase (Quinone); NADP; Oxidation-Reduction; Rats; Structure-Activity Relationship; Superoxides | 1992 |
Mitoxantrone and ametantrone inhibit hydroperoxide-dependent initiation and propagation reactions in fatty acid peroxidation.
Topics: Anthraquinones; Antineoplastic Agents; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Kinetics; Linoleic Acid; Linoleic Acids; Lipid Peroxides; Micelles; Mitoxantrone; Spectrophotometry; Xanthine Oxidase | 1985 |