hydroxyl radical has been researched along with allopurinol in 263 studies
| Studies (hydroxyl radical) | Trials (hydroxyl radical) | Recent Studies (post-2010) (hydroxyl radical) | Studies (allopurinol) | Trials (allopurinol) | Recent Studies (post-2010) (allopurinol) |
|---|---|---|---|---|---|
| 10,147 | 26 | 3,657 | 15,096 | 743 | 3,363 |
| Protein | Taxonomy | hydroxyl radical (IC50) | allopurinol (IC50) |
|---|---|---|---|
| Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase | Rattus norvegicus (Norway rat) | 3.3765 | |
| Xanthine dehydrogenase/oxidase | Homo sapiens (human) | 3.1861 | |
| Xanthine dehydrogenase/oxidase | Bos taurus (cattle) | 5.0758 | |
| Histamine H3 receptor | Cavia porcellus (domestic guinea pig) | 8.69 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 87 (33.08) | 18.7374 |
| 1990's | 110 (41.83) | 18.2507 |
| 2000's | 54 (20.53) | 29.6817 |
| 2010's | 12 (4.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ciofani, G; Cuccurullo, F; de Gioia, S; Di Ilio, C; Lapenna, D; Marzio, L; Mezzetti, A | 1 |
| Halliwell, B; Hoult, JR; Payá, M | 1 |
| Arakawa, T; Kobayashi, K; Sakuma, H | 1 |
| Deby, C; Deby-Dupont, G; Emerit, I; Franchimont, P; Henrotin, Y | 1 |
| Butler, J; de Mol, NJ; Hoey, BM; Janssen, LH; Lusthof, KJ; Reinhoudt, DN; Richter, W; Verboom, W | 1 |
| Aisen, P; Barthakur, SR; Egan, TJ | 1 |
| Miura, T; Muraoka, S; Ogiso, T | 1 |
| Hori, H; Nakagawa, Y; Niijima, T; Ojima, H; Terada, H | 1 |
| Guidot, DM; Leff, JA; Repine, JE; Terada, LS; Willingham, IR | 1 |
| Pang, JA; Smith, S; Thomas, MJ | 1 |
| Antczak, A; Nowak, D; Piasecka, G; Pietras, T | 1 |
| Benes, L; Stefek, M | 2 |
| Colton, C; Gilbert, D; Grossman, Y; Yao, J | 1 |
| Dongari, AI; Miyasaki, KT | 1 |
| Eneff, K; Floyd, RA; Gutteridge, JM; West, M | 1 |
| Spragg, RG | 1 |
| Freeman, D; Hollander, D; Krugliak, P; Ma, TY; Nguyen, T | 1 |
| Salim, AS | 5 |
| Burkitt, MJ; Gilbert, BC | 1 |
| Griot, C; Peterhans, E; Richard, A; Stocker, R; Vandevelde, M | 1 |
| Halliwell, B; Kaur, H | 1 |
| Babbs, CF; Cusumano, JC; Smith, JB | 1 |
| Han, ZW; Ju, HS; Li, XJ; Xin, WJ; Zhao, BL | 1 |
| Callahan, HL; Crouch, RK; James, ER | 1 |
| Doria, M; Gordon, JH; Keshavarzian, A; Morgan, G; Sedghi, S | 1 |
| Lloyd, RV; Mason, RP | 1 |
| Britigan, BE; Buettner, GR; Lilleg, DM; Pou, S; Rosen, GM | 1 |
| Bromont, C; Constantin, M; Fickat, R; Massingham, R | 1 |
| Gibbs, DF; Phan, SH; Ryan, US; Varani, J; Ward, PA | 1 |
| Bagchi, D; Das, DK; Prasad, R | 1 |
| Coulombe, RA; Grover, TA; Keller, RJ; Piette, LH; Sharma, RP | 1 |
| Cederbaum, AI; Puntarulo, S | 2 |
| Aruoma, OI; Halliwell, B | 1 |
| Kuppusamy, P; Zweier, JL | 1 |
| Friedl, HP; Guilds, LS; Mahrougui, M; Till, GO; Trentz, O; Ward, PA | 1 |
| Hiraishi, H; Ota, S; Shiga, J; Sugimoto, T; Terano, A | 1 |
| Bacon, BR; Grisham, MB; Inauen, W; Kvietys, PR | 1 |
| Becker, BF; Gerlach, E; Leipert, B; Ozçelik, T; Reinholz, N | 1 |
| Aruoma, OI; Halliwell, B; Laughton, MJ | 1 |
| Barta, E | 1 |
| Brunahl, D; Damerau, B; Nolte, R; Vogt, W; von Zabern, I | 1 |
| LaMont, JT | 1 |
| Friedl, HP; Till, GO; Trentz, O; Ward, PA | 1 |
| Amma, EL; Griffith, EH; Huber, KR; Roberts, J; Sridhar, R | 1 |
| Castelli, A; Martorana, GE; Meucci, E; Miggiano, GA; Mordente, A; Santini, SA | 1 |
| Clement, R; Das, DK; Engelman, RM; Otani, H; Prasad, MR; Rao, PS | 1 |
| McCord, JM; Turrens, JF | 1 |
| Campbell, TJ | 1 |
| Boegheim, JP; Dubbelman, TM; Van der Zee, J; Van Steveninck, J | 1 |
| Hess, ML; Schrier, GM | 1 |
| Cochrane, CG; Hyslop, PA; Jackson, JH; Schraufstätter, I | 1 |
| Belluk, B; Gupta, M; Singal, PK | 1 |
| Butler, J; Halliwell, B; Hoey, BM | 1 |
| Buc-Calderon, P; Roberfroid, M | 1 |
| Alexander, NM; Bagnell, R; Hale, B; Kelner, MJ | 1 |
| Archibald, FS; Cheton, PL | 1 |
| Betts, WH; Cleland, LG; Vernon-Roberts, B; Whitehouse, MW | 1 |
| Alesiani, M; Carlà, V; Cherici, G; Moroni, F; Pellegrini-Giampietro, DE | 1 |
| Aust, SD; Morehouse, LA; Thomas, CE | 1 |
| Guth, PH; Itoh, M | 1 |
| Crute, SL; Greenfield, LJ; Hess, ML; Loughlin, V; Stewart, JR | 1 |
| Kharasch, ED; Novak, RF | 1 |
| Weaver, WM; Wilson, CB | 1 |
| Kontos, HA | 1 |
| de Mello Filho, AC; Meneghini, R | 1 |
| Fellman, JH; Roth, ES | 1 |
| Sutton, HC; Winterbourn, CC | 2 |
| Hanaki, A; Ozawa, T | 1 |
| Imamura, S; Miyachi, Y; Niwa, Y; Yoshioka, A | 2 |
| Winterbourn, CC | 2 |
| Fitzgeorge, RB; Jepras, RI | 1 |
| Cataldi de Flombaum, MA; Stoppani, AO | 1 |
| Weiss, SJ | 1 |
| Cederbaum, AI; Winston, GW | 1 |
| Kikuchi, T; Komiyama, T; Sugiura, Y | 1 |
| Rosen, GM; Turner, MJ | 1 |
| Aisen, P; Doi, K; Sibille, JC | 1 |
| Shimada, O; Yasuda, H | 1 |
| Grootveld, M; Gutteridge, JM; Halliwell, B; Moorhouse, PC; Quinlan, JG | 1 |
| Fridovich, I; Mashino, T | 1 |
| Dykens, JA; Stern, A; Trenkner, E | 1 |
| Lauwerys, R; Scailteur, V | 1 |
| Granger, DN; Parks, DA; Shah, AK | 1 |
| Miyachi, Y; Niwa, Y; Sakane, T | 1 |
| Arfors, KE; Del Maestro, RF; Planker, M | 1 |
| Gutteridge, JM | 2 |
| Carlin, G; Djursäter, R | 1 |
| Mittag, T | 1 |
| Arfors, KE; Björk, J; del Maestro, RF | 1 |
| Rosen, H | 1 |
| Cederbaum, AI; Cohen, G; Klein, SM | 1 |
| Chauhan, J; Darbre, A; Halliwell, B; Richmond, R | 1 |
| Bannister, JV; Bannister, WH; Hill, HA; Thornalley, PJ | 1 |
| Leutchev, SI; Ljutakova, SG; Russanov, EM | 1 |
| Aust, SD; Svingen, BA; Tien, M | 1 |
| Berl, L; Cederbaum, AI | 1 |
| Klebanoff, SJ | 1 |
| Gutteridge, JM; Halliwell, B | 1 |
| Belvedere, G; Tursi, F | 1 |
| Henderson, WR; Klebanoff, SJ | 1 |
| Mori, I; Motohashi, N | 1 |
| Granger, DN; Parks, DA | 1 |
| Cederbaum, AI; Cohen, G; Qureshi, A | 1 |
| Gutteridge, JM; Quinlan, GJ; Wilkins, S | 1 |
| Ito, H; Odajima, C; Okabe, E; Todoki, K | 1 |
| Bryant, RG; Eaton, JW; Graf, E; Mahoney, JR | 1 |
| Burton, KP; Ghai, G; McCord, JM | 1 |
| Cederbaum, AI; Feierman, DE; Winston, GW | 1 |
| Anderson, RF; Hille, R; Patel, KB | 1 |
| Coudray, C; Favier, A; Rachidi, S | 1 |
| Aruoma, OI; Butler, J; Halliwell, B; Scott, BC | 1 |
| Benedict, CR; Pakala, R | 1 |
| Dzwigaj, S; Pezerat, H | 1 |
| Arai, T; Iizuka, I; Kojima, S; Kubota, K; Mori, H; Ona, S | 1 |
| Kabuto, H; Liu, J; Mori, A; Toma, J; Yokoi, I | 1 |
| Aizenman, E | 1 |
| Mombourquette, MJ; Richardson, JS; Weil, JA; Zhao, W | 1 |
| Hasinoff, BB; Malisza, KL | 1 |
| Felix, CC; Kalyanaraman, B; Pieper, GM; Roza, AM; Turk, M | 1 |
| Mao, Y; Shi, X; Zang, L | 1 |
| Scaduto, RC | 1 |
| Hassoun, PM; Lanzillo, JJ; White, AC; Yu, FS; Zulueta, JJ | 1 |
| Droy-Lefaix, MT; Gardès-Albert, M; Marcocci, L; Packer, L; Sekaki, A | 1 |
| Dreher, D; Junod, AF | 1 |
| Lokesh, BR; Reddy, AC | 1 |
| Ichikawa, H; Kondo, M; Minamiyama, Y; Naito, Y; Takahashi, S; Tanigawa, T; Yoshikawa, T | 1 |
| Bannenberg, GL; Moldéus, P; Shertzer, HG; Zhu, H | 1 |
| Arai, T; Makino, K; Mori, H; Mori, K; Tsutsui, H | 1 |
| Feuerstein, R; Yue, TL | 1 |
| Matsumoto, T; Moriguchi, R; Yamada, H | 1 |
| Fraisse, L; Rabion, A; Roche, B; Seris, JL; Verlhac, JB | 1 |
| Manso, CF; Mira, ML; Queiroz, MJ; Silva, MM | 1 |
| Frei, B; Lynch, SM | 1 |
| Campisi, A; Castorina, C; Di Giacomo, C; Fichera, C; Latteri, F; Pinturo, R; Russo, A; Sorrenti, V; Vanella, A | 1 |
| Dalal, NS; Shi, X | 1 |
| Hori, H; Nakagawa, Y; Terada, H; Yamamoto, I | 1 |
| Lopaschuk, GD; Mao, GD; Poznansky, MJ; Thomas, PD | 1 |
| Fukui, K; Hatanaka, R; Iwabuchi, S; Koyama, K; Narita, J; Suzuki, S; Takahashi, S; Takaya, S; Takeuchi, K; Yamada, Y | 1 |
| Thomas, C; Vile, GF; Winterbourn, CC | 1 |
| Darley-Usmar, VM; Hogg, N; Moncada, S; Wilson, MT | 1 |
| Manso, CF; Mira, ML | 1 |
| Adams, JD; Cadenas, E; Kim, SS; Klaidman, LK; Leung, AC | 1 |
| Adams, JD; Klaidman, LK | 1 |
| Kijlstra, A; Kuizenga, A; van Haeringen, NJ | 1 |
| Adams, G; Bernotas, RC; Carr, AA; Hay, DA; Nieduzak, TR; Ohlweiler, DF; Thomas, CE; Vaz, R | 1 |
| Khatchikian, G; Xia, Y; Zweier, JL | 1 |
| Lee, YT; Tsai, KL; Wang, BS; Wang, SM; Wu, JC; Wu, ML | 1 |
| Fay, LB; Richoz, J; Stadler, RH; Turesky, RJ; Welti, DH | 1 |
| Babin-Chevaye, C; Franzini, E; Hakim, J; Marquetty, C; Pasquier, C; Sellak, H | 1 |
| Bartsch, H; Owen, RW; Spiegelhalder, B; Wimonwatwatee, T | 1 |
| Itoh, T; Kamisaki, Y; Nakamoto, K; Wada, K | 1 |
| Doi, M; Ishida, T; Murakami, S; Otsuka, M; Satake, H; Shibasaki, M; Sugiura, Y | 1 |
| Dhople, AM | 1 |
| Clerici, WJ; Yang, L | 1 |
| Albasini, A; Costantino, L; Rastelli, G | 1 |
| Karolczak, S; Metodiewa, D; Skolimowski, J | 1 |
| Cho, SW; Hahm, KB; Kim, JH; Kim, YS; Lee, SI; Park, IS; Youn, JK | 1 |
| Fujimoto, Y; Fujita, T; Nishida, H; Sakamoto, Y; Sakuma, S; Uchiyama, T; Yoshioka, K | 1 |
| Akiyama, K; Aoyagi, K; Koyama, A; Nagase, S; Takemura, K; Tomida, C | 1 |
| Itoh, T; Kamisaki, Y; Kishimoto, Y; Kitano, M; Nakamoto, K; Wada, K | 1 |
| Masaki, H; Sakurai, H | 1 |
| Obata, T; Yamanaka, Y | 3 |
| Hill, J; Jackson, JH; Kuo, CY; Mitra, G; Rodriguez, H; Schwabacher, AW; Vollenweider, M | 1 |
| Kimura, K | 1 |
| Kerjaschki, D; Riedle, B | 1 |
| Chao, HT; Chen, CS; Pan, RL; Wei, YH | 1 |
| Dietz, R; Li, PF; von Harsdorf, R | 1 |
| Dorey, G; Nepveu, F; Rolland, Y; Souchard, JP; Spedding, M | 1 |
| Chu, LH; Gau, RJ; Lu, FJ | 1 |
| Elbim, C; Gougerot-Pocidalo, MA; Grange, MJ; Marquetty, C; Pasquier, C; Rollet-Labelle, E | 1 |
| Brunet, J; Farine, JC; Garay, RP; Hannaert, P | 1 |
| Abad, MJ; Benedí, J; Bermejo, P; Carretero, E; Chiriboga, X; de las Heras, B; Gómez-Serranillos, P; Iglesias, I; Liso, PA; Ortega, T; Slowing, K; Toledo, C; Villar, A | 1 |
| Pallauf, J; Rimbach, G | 1 |
| Arita, M; Kiyosue, T; Tokube, K | 1 |
| Hermes-Lima, M; Nagy, E; Ponka, P; Schulman, HM | 1 |
| Andrieu, V; Da Costa, L; Franzini, E; Gozin, A; Pasquier, C; Rollet-Labelle, E | 1 |
| Brackett, DJ; McCay, PB; Wallis, G; Wilson, MF | 1 |
| Burkhardt, G; Horsch, E; Köhler, H; Kuhlmann, MK; Wagner, M | 1 |
| Ali, SF; Hussain, S | 1 |
| Eguchi, H; Koh, YH; Park, YS; Suzuki, K; Taniguchi, N | 1 |
| Bruchelt, G; Gerber, CE; Schweinsberg, F; Speer, CP; Stegmann, H | 1 |
| Az-ma, T; Saeki, N; Yuge, O | 1 |
| Bulera, SJ; de la Iglesia, FA; Festerling, TA; Theiss, JC | 1 |
| Graziewicz, MA; Oliński, R; Tudek, B; Zastawny, TH | 1 |
| Kawai, Y; Nakagawa, Y; Ogamo, A | 1 |
| Carloni, P; Damiani, E; Greci, L; Stipa, P | 1 |
| Courderot-Masuyer, C; Dalloz, F; Maupoil, V; Rochette, L | 1 |
| Bartsch, H; Owen, RW; Spiegelhalder, B | 1 |
| Graziewicz, MA; Oliński, R; Siedlecki, J; Speina, E; Tudek, B; Zastawny, TH | 1 |
| Ding, M; Rojanasakul, Y; Shi, X; Ye, J; Zhang, X | 1 |
| Blume, R; Brömme, HJ; Ebelt, H; Mörke, W; Peschke, D; Peschke, E | 1 |
| Joseph, J; Kalyanaraman, B; Karoui, H; Martásek, P; Nsanzumuhire, C; Tordo, P; Vasquez-Vivar, J; Zhang, H | 1 |
| Barth, ED; Casara, P; Dorey, G; Halpern, HJ; Rosen, GM; Spedding, M; Tsai, P | 1 |
| Belcher, JD; Choong, S; Hebbel, RP; Osarogiagbon, UR; Paller, MS; Vercellotti, GM | 1 |
| Tamura, K; Wada-Takahashi, S | 1 |
| Hara, A; Ito, Z; Kusakari, J; Tabuchi, K; Tsuji, S | 1 |
| Gillespie, MN; Grishko, V; LeDoux, SP; Solomon, M; Wilson, GL | 1 |
| Azuma, M; Houchi, H; Kameda, T; Kirima, K; Tamaki, T; Tsuchiya, K; Yoshizumi, M | 1 |
| Kubota, S; Obata, T; Yamanaka, Y | 1 |
| Chang, MC; Chen, SY; Hahn, LJ; Jeng, JH; Liao, CH; Lin, BR; Tung, YY | 1 |
| Burkitt, MJ; Jones, CM; Lawrence, A; Wardman, P | 1 |
| Kamendulis, LM; Klaunig, JE; Zhang, H | 1 |
| Baxter, GF; CsonkA, C; Csont, T; Dux, L; Ferdinandy, P; Görbe, A; Onody, A; Schulz, R | 1 |
| Chen, R; Stenken, JA | 1 |
| Guo, Q; Moini, H; Packe, L | 1 |
| Mikuni, T; Tatsuta, M | 1 |
| Chan, CP; Chang, MC; Huang, CS; Jeng, JH; Lan, WH; Lin, CP; Yeung, SY | 1 |
| Iwabuchi, H; Kamiichi, H; Mimura, H; Miura, S; Nakamura, T; Ro, S; Yakabi, K | 1 |
| Furuse, Y; Hisatome, I; Igawa, O; Kinugasa, Y; Ogino, K; Shigemasa, C; Shiomi, T; Tsutsui, H; Yamamoto, T | 1 |
| Elstner, EF; Schempp, H; Toth, A; Weiser, D | 1 |
| De Pascual-Teresa, S; Ewins, BA; Matsugo, S; Minihane, AM; Rimbach, G; Turner, R; Uchida, Y; VafeiAdou, K; Weinberg, PD | 1 |
| Bridts, CH; Cos, P; De Clerck, LS; Dombrecht, EJ; Schuerwegh, AJ; Stevens, WJ; Van Offel, JF; Vanden Berghe, D | 1 |
| Freisleben, HJ; Murakami, A; Rumampuk, RJ; Safitri, R; Tarigan, P | 1 |
| Hyodo, F; Kasazaki, K; Utsumi, H; Yasukawa, K | 1 |
| Fujimoto, Y; Sakuma, S; Uno, E | 1 |
| Elstner, EF; Janisch, KM; Milde, J | 1 |
| Akamatsu, H; Mikawa, K; Nishina, K; Niwa, Y; Obara, H | 1 |
| Ho, CT; Liao, CH; Lin, JK | 1 |
| Casagrande, R; Di Mambro, VM; Fonseca, MJ; Georgetti, SR; Marquele, FD; Valim, YM | 1 |
| Burlando, B; Viarengo, A | 1 |
| Campa, A; Catalani, LH; Kettle, AJ; Maghzal, GJ; Rodrigues, MR; Silva, SO; Ximenes, VF | 1 |
| Lee, J; Simurdiak, M; Zhao, H | 1 |
| Obata, T | 1 |
| Anderson, R; Fickl, H; Grimmer, H; Oommen, J; Ramafi, GJ; Steel, HC; Theron, AJ; Visser, SS | 1 |
| Antus, S; Balla, G; Balla, J; Nagy, E; Seres, I; Ujhelyi, L; Varga, Z | 1 |
| Chen, DF; Chen, JK; Lei, GQ; Liao, ZX; Liu, ZJ; Wu, Q; Yao, H; Zhou, TS | 1 |
| Huang, SS; Zheng, RL | 1 |
| Chen, KT; Chien, SP; Chuang, YC; Hsu, DZ; Huang, BM; Li, YH; Liu, MY | 1 |
| Chekulayev, V; Chekulayeva, L; Oginskaya, E; Shevchuk, I | 1 |
| Andrade, PB; Baptista, P; Ribeiro, B; Seabra, RM; Valentão, P | 1 |
| Chen, KT; Chien, SP; Hsu, DZ; Liu, MY | 1 |
| Aboy, AL; Bassani, VL; Behr, GA; Bordignon, CL; Dal-Pizzol, F; Henriques, AT; Lorenzi, R; Moreira, JC; Pasquali, MA; Ravazolo, LG; Reginatto, FH; Silva, EG; Silva, FA; Zanotto-Filho, A | 1 |
| Batista, MT; Correia, HS; Dinis, TC | 1 |
| Kato, M; Kohno, M; Niwano, Y; Sato, E | 1 |
| Kohno, M; Nakashima, T; Niwano, Y; Sato, E | 1 |
| Hsu, DZ; Hsu, HF; Lin, YM; Liu, MY; Wan, CH | 1 |
| Kamibayashi, M; Kohno, M; Mokudai, T; Niwano, Y; Sato, E | 1 |
| Aisen, E; Esteso, MC; Fernández-Santos, MR; García-Alvarez, O; Garde, JJ; Maroto-Morales, A; Martínez-Pastor, F | 1 |
| Hiramoto, K; Inukai, Y; Kaji, H; Maiguma, T; Makino, K; Ono, H; Teshima, D | 1 |
| Du, D; Li, Y; Ma, X; Zhang, J; Zhang, Y; Zhou, X | 1 |
| Busto, MD; Cavia-Saiz, M; Muñiz, P; Ortega, N; Perez-Mateos, M; Pilar-Izquierdo, MC | 1 |
| Pospišil, P; Prasad, A | 1 |
| Arimboor, R; Arumughan, C | 2 |
| Kumar, B; Nile, SH; Park, SW | 1 |
| Chandrasekaran, VR; Hsu, DZ; Liu, MY | 1 |
| Iagupols'kyĭ, IuL; Kotsiuruba, AV; Moĭbenko, OO; Rovenets', RA; Sagach, VF; Strutyns'ka, NA; Strutyns'kyĭ, RB | 1 |
| Begum, AB; Hegdekatte, R; Khanum, SA; Naveen, P; Ranganatha, VL; Zameer, F | 1 |
| Kop"iak, BS; Kotsiuruba, AV; Sahach, VF; Sharipov, RR | 1 |
| Sakamoto, K; Tatsumi, H; Tsuchiya, Y | 1 |
| Brigante, M; Cimafonte, M; Fabio, GD; Gravante, R; Mailhot, G; Marino, CD; Romanucci, V; Zarrelli, A | 1 |
6 review(s) available for hydroxyl radical and allopurinol
| Article | Year |
|---|---|
Active oxygen species, articular inflammation and cartilage damage.
Topics: Aging; Animals; Antioxidants; Arthritis; Cartilage, Articular; DNA Damage; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; Inflammation; Joints; Lipid Peroxidation; Xanthine Oxidase | 1992 |
The role of free oxygen radicals in the mechanism of ischaemic-reperfusion myocardial injury.
Topics: Animals; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; Myocardial Reperfusion Injury; Oxygen; Superoxides; Xanthine Oxidase | 1989 |
George E. Brown memorial lecture. Oxygen radicals in cerebral vascular injury.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Arterioles; Blood Proteins; Blood-Brain Barrier; Bradykinin; Brain; Brain Injuries; Cardiovascular Agents; Catalase; Cerebrovascular Circulation; Cerebrovascular Disorders; Cyclooxygenase Inhibitors; Endothelium; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Hypertension; Leukocytes; Leukotrienes; Lipid Peroxides; Muscle, Smooth, Vascular; Peroxidases; Prostaglandin-Endoperoxide Synthases; Prostaglandins G; Superoxide Dismutase; Superoxides; Vasodilation; Xanthine Oxidase | 1985 |
Role of hydroxyl radical in polymorphonuclear leukocyte-mediated bactericidal activity.
Topics: Acetaldehyde; Blood Bactericidal Activity; Cyclic N-Oxides; Free Radicals; Halogens; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Neutrophils; Oxygen; Peroxidase; Phagocytosis; Xanthine Oxidase | 1980 |
[Alcohol and free oxygen radicals].
Topics: Animals; Biotransformation; Ethanol; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; Lipid Peroxidation; Oxygen Consumption; Xanthine Dehydrogenase; Xanthine Oxidase | 1993 |
Beneficial effect of sesame oil on heavy metal toxicity.
Topics: Benzodioxoles; Chelating Agents; Heavy Metal Poisoning; Humans; Hydroxyl Radical; Interleukin-1beta; Iron; Kidney; Lipid Peroxidation; Liver; Nitric Oxide; Phenols; Poisoning; Sesame Oil; Superoxides; Tumor Necrosis Factor-alpha; Xanthine Oxidase | 2014 |
3 trial(s) available for hydroxyl radical and allopurinol
| Article | Year |
|---|---|
Oxygen-derived free radicals and the prevention of duodenal ulcer relapse: a new approach.
Topics: Allopurinol; Cimetidine; Dimethyl Sulfoxide; Duodenal Ulcer; Female; Follow-Up Studies; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; Male; Middle Aged; Prospective Studies; Random Allocation; Recurrence; Smoking | 1990 |
Scavenging free radicals to prevent stress-induced gastric mucosal injury.
Topics: Adult; Allopurinol; Dimethyl Sulfoxide; Female; Free Radicals; Gastric Mucosa; Humans; Hydroxides; Hydroxyl Radical; Male; Middle Aged; Prospective Studies; Randomized Controlled Trials as Topic; Stomach Ulcer; Stress, Physiological; Superoxides | 1989 |
Role of free radical scavengers in the management of refractory duodenal ulceration. A new approach.
Topics: Adult; Aged; Alcohol Drinking; Allopurinol; Cimetidine; Dimethyl Sulfoxide; Double-Blind Method; Drug Therapy, Combination; Duodenal Ulcer; Female; Free Radical Scavengers; Humans; Hydroxyl Radical; Male; Middle Aged; Prospective Studies; Recurrence; Smoking; Xanthine Oxidase | 1994 |
254 other study(ies) available for hydroxyl radical and allopurinol
| Article | Year |
|---|---|
Heparin: does it act as an antioxidant in vivo?
Topics: Animals; Antioxidants; Free Radicals; Heparin; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; Lipid Peroxidation; Superoxides; Xanthine Oxidase | 1992 |
Interactions of a series of coumarins with reactive oxygen species. Scavenging of superoxide, hypochlorous acid and hydroxyl radicals.
Topics: Animals; Coumarins; Female; Free Radical Scavengers; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Hypochlorous Acid; Inflammation; Lipid Peroxidation; Male; Microsomes, Liver; Rats; Rats, Inbred Strains; Superoxides; Xanthine Oxidase | 1992 |
Effects of active oxygen species on damage to and prostaglandin synthesis in cultured rat gastric cells.
Topics: Animals; Catalase; Cells, Cultured; Gastric Mucosa; Hydroxides; Hydroxyl Radical; Indomethacin; Male; Oxygen; Prostaglandins; Rats; Rats, Inbred Strains; Xanthine; Xanthine Oxidase; Xanthines | 1992 |
Redox cycling of potential antitumor aziridinyl quinones.
Topics: Antineoplastic Agents; Aziridines; DNA Damage; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Oxidation-Reduction; Quinones; Reactive Oxygen Species; Superoxides; Xanthine Oxidase | 1992 |
Catalysis of the Haber-Weiss reaction by iron-diethylenetriaminepentaacetate.
Topics: Catalase; Catalysis; Electron Spin Resonance Spectroscopy; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Iron; Oxidation-Reduction; Pentetic Acid; Superoxide Dismutase; Superoxides; Xanthine; Xanthine Oxidase; Xanthines | 1992 |
Oxidative damage to bovine serum albumin induced by hydroxyl radical generating systems of xanthine oxidase + EDTA-Fe3+ and ascorbate + EDTA-Fe3+.
Topics: Amines; Animals; Ascorbic Acid; Cattle; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Ferric Compounds; Fluorescence; Hydroxides; Hydroxyl Radical; Oxidation-Reduction; Serum Albumin, Bovine; Sodium Dodecyl Sulfate; Sulfhydryl Compounds; Xanthine Oxidase | 1992 |
Biologically active cyanine dyes as probes for the identification of active oxygen species.
Topics: Coloring Agents; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Indicators and Reagents; Indoles; Iron; Superoxides; Xanthine; Xanthine Oxidase; Xanthines | 1992 |
Inactivation of xanthine oxidase by hydrogen peroxide involves site-directed hydroxyl radical formation.
Topics: Dimethyl Sulfoxide; Enzyme Activation; Formaldehyde; Free Radical Scavengers; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Pentetic Acid; Substrate Specificity; Superoxide Dismutase; Xanthine Oxidase | 1991 |
The use of water-soluble radical scavengers to detect hydroxyl radical formation by polymorphonuclear leukocytes.
Topics: Allopurinol; Benzoates; Benzoic Acid; Cytochrome c Group; Dimethyl Sulfoxide; Free Radical Scavengers; Free Radicals; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; L-Lactate Dehydrogenase; Mannitol; Neutrophils; Oxidation-Reduction; Solubility; Tetradecanoylphorbol Acetate; Thiourea; Water | 1991 |
Effect of ascorbic acid on hydroxyl radical generation by chemical, enzymatic and cellular systems. Importance for antioxidant prevention of pulmonary emphysema.
Topics: Animals; Antioxidants; Ascorbic Acid; Deoxyribose; Dithiothreitol; Edetic Acid; Ferrous Compounds; Free Radicals; Glutathione; Hydroxides; Hydroxyl Radical; Macrophages; Male; Mannitol; Mercaptoethanol; Mice; Neutrophils; Oxidation-Reduction; Pulmonary Emphysema; Tetradecanoylphorbol Acetate; Xanthine Oxidase | 1991 |
Pyridoindole stobadine is a potent scavenger of hydroxyl radicals.
Topics: Animals; Binding, Competitive; Carbolines; Deoxyribose; Electron Transport; Ethylenes; Free Radical Scavengers; Hydroxides; Hydroxyl Radical; Kinetics; Male; Methionine; Microsomes, Liver; NADP; Oxidation-Reduction; Rats; Rats, Inbred Strains; Xanthine; Xanthine Oxidase; Xanthines | 1991 |
The effect of xanthine/xanthine oxidase generated reactive oxygen species on synaptic transmission.
Topics: Action Potentials; Animals; Decapodiformes; Depression, Chemical; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Membrane Potentials; Nephropidae; Neuromuscular Junction; Oxygen; Superoxides; Synapses; Synaptic Transmission; Xanthine; Xanthine Oxidase; Xanthines | 1991 |
Sensitivity of Actinobacillus actinomycetemcomitans and Haemophilus aphrophilus to oxidative killing.
Topics: Aggregatibacter actinomycetemcomitans; Blood Bactericidal Activity; Free Radicals; Haemophilus; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Microbial Sensitivity Tests; Oxidants; Oxidation-Reduction; Phagocytes; Superoxide Dismutase; Superoxides; Xanthine Oxidase; Xanthines | 1991 |
Bleomycin-iron damage to DNA with formation of 8-hydroxydeoxyguanosine and base propenals. Indications that xanthine oxidase generates superoxide from DNA degradation products.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Bleomycin; Cattle; Deoxyguanosine; DNA; DNA Damage; Electron Spin Resonance Spectroscopy; Free Radicals; Guanine; Hydroxides; Hydroxyl Radical; Iron; Superoxides; Thiobarbiturates; Xanthine Oxidase | 1990 |
DNA strand break formation following exposure of bovine pulmonary artery and aortic endothelial cells to reactive oxygen products.
Topics: Animals; Aorta; Cattle; Cells, Cultured; Chromium; DNA Damage; Endothelium, Vascular; Free Radicals; Glucose Oxidase; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; L-Lactate Dehydrogenase; Pulmonary Artery; Superoxides; Xanthine Oxidase | 1991 |
Oxygen free radical injury of IEC-18 small intestinal epithelial cell monolayers.
Topics: Animals; Catalase; Cell Line; Deferoxamine; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Intestine, Small; Microscopy, Phase-Contrast; Rats; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1991 |
A possible new approach to the problem of refractory peptic ulceration. A role for free radical scavengers?
Topics: Adult; Allopurinol; Chronic Disease; Cimetidine; Dimethyl Sulfoxide; Duodenal Ulcer; Female; Free Radical Scavengers; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; Male; Middle Aged; Stomach Ulcer | 1991 |
Model studies of the iron-catalysed Haber-Weiss cycle and the ascorbate-driven Fenton reaction.
Topics: Ascorbic Acid; Citrates; Citric Acid; Edetic Acid; Electron Spin Resonance Spectroscopy; Ferric Compounds; Ferrous Compounds; Hydroxides; Hydroxyl Radical; Hydroxylation; Iron; Nitrilotriacetic Acid; Oxidation-Reduction; Pentetic Acid; Phytic Acid; Salicylates; Salicylic Acid; Succinates; Succinic Acid; Xanthine; Xanthine Oxidase; Xanthines | 1990 |
Selective degeneration of oligodendrocytes mediated by reactive oxygen species.
Topics: Animals; Benzamides; Brain; Cell Survival; Cells, Cultured; Demyelinating Diseases; Dogs; Free Radical Scavengers; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Oligodendroglia; Oxygen; Superoxides; Theophylline; Xanthine; Xanthine Oxidase; Xanthines | 1990 |
Action of biologically-relevant oxidizing species upon uric acid. Identification of uric acid oxidation products.
Topics: Allantoin; Ceruloplasmin; Chromatography, High Pressure Liquid; Edetic Acid; Ferric Compounds; Hemoglobins; Hydantoins; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Hypochlorous Acid; Hypoxanthine; Hypoxanthines; Imidazoles; Kinetics; Molecular Structure; Myoglobin; Oxidation-Reduction; Oxonic Acid; Uric Acid; Xanthine Oxidase | 1990 |
Quantitative effects of iron chelators on hydroxyl radical production by the superoxide-driven fenton reaction.
Topics: Chemical Phenomena; Chemistry; Free Radicals; Hydroxides; Hydroxyl Radical; Iron Chelating Agents; Sulfinic Acids; Superoxides; Xanthine Oxidase | 1990 |
Scavenging effect of berbamine on active oxygen radicals in phorbol ester-stimulated human polymorphonuclear leukocytes.
Topics: Alkaloids; Benzylisoquinolines; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; Neutrophils; Oxygen Consumption; Riboflavin; Spin Labels; Superoxides; Tetradecanoylphorbol Acetate; Xanthine Oxidase | 1990 |
Hydrogen peroxide is the most toxic oxygen species for Onchocerca cervicalis microfilariae.
Topics: Animals; Catalase; Glucose Oxidase; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Microfilariae; Onchocerca; Oxygen; Rose Bengal; Singlet Oxygen; Superoxide Dismutase; Superoxides; Thiourea; Xanthine; Xanthine Oxidase; Xanthines | 1990 |
Role of reactive oxygen metabolites in experimental colitis.
Topics: Animals; Colitis; Female; Free Radicals; Hydroxides; Hydroxyl Radical; Oxygen; Rats; Superoxides; Xanthine Oxidase | 1990 |
Evidence against transition metal-independent hydroxyl radical generation by xanthine oxidase.
Topics: Catalase; Deferoxamine; Electron Spin Resonance Spectroscopy; Free Radicals; Hydroxides; Hydroxyl Radical; Kinetics; Metals; Spin Labels; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1990 |
Hydroxyl radical is not a product of the reaction of xanthine oxidase and xanthine. The confounding problem of adventitious iron bound to xanthine oxidase.
Topics: Animals; Cattle; Electron Spin Resonance Spectroscopy; Female; Free Radicals; Hydroxides; Hydroxyl Radical; Iron; Iron Chelating Agents; Milk; Protein Binding; Xanthine; Xanthine Oxidase; Xanthines | 1990 |
Studies on the activity of bepridil as a scavenger of free radicals.
Topics: Allopurinol; Alloxan; Animals; Antioxidants; Bepridil; Biphenyl Compounds; Cytochrome c Group; Deoxyribose; Diabetes Mellitus, Experimental; Drug Interactions; Free Radical Scavengers; Hydroxides; Hydroxyl Radical; Mice; Oxidation-Reduction; Picrates; Superoxide Dismutase | 1990 |
H2O2-mediated cytotoxicity of rat pulmonary endothelial cells. Changes in adenosine triphosphate and purine products and effects of protective interventions.
Topics: Adenosine Triphosphate; Animals; Catalase; Chromatography, High Pressure Liquid; Chromium Isotopes; Endothelium; Enzyme Activation; Hydrogen Peroxide; Hydrolysis; Hydroxides; Hydroxyl Radical; Hypoxanthines; Kinetics; Pulmonary Artery; Rats; Rats, Inbred Strains; Superoxides; Xanthine Oxidase; Xanthines | 1990 |
Direct scavenging of free radicals by captopril, an angiotensin converting enzyme inhibitor.
Topics: Allopurinol; Captopril; Cytochrome c Group; Free Radicals; Hydroxides; Hydroxyl Radical; Hypochlorous Acid; Kinetics; Superoxide Dismutase; Superoxides; Thiourea | 1989 |
Importance of hydroxyl radical in the vanadium-stimulated oxidation of NADH.
Topics: Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxides; Hydroxyl Radical; NAD; Oxidation-Reduction; Spectrophotometry; Spin Labels; Superoxides; Vanadates; Vanadium; Xanthine; Xanthine Oxidase; Xanthines | 1989 |
Chemiluminescence from acetaldehyde oxidation by xanthine oxidase involves generation of and interactions with hydroxyl radicals.
Topics: Acetaldehyde; Catalase; Humans; Hydroxides; Hydroxyl Radical; Liver; Liver Diseases, Alcoholic; Luminescent Measurements; Superoxide Dismutase; Xanthine Oxidase | 1989 |
Inactivation of alpha 1-antiproteinase by hydroxyl radicals. The effect of uric acid.
Topics: alpha 1-Antitrypsin; Ascorbic Acid; Blood Proteins; Chemical Phenomena; Chemistry; Edetic Acid; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxides; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; Indomethacin; Iron; Nitrous Oxide; Pancreatic Elastase; Piroxicam; Protease Inhibitors; Pulse Radiolysis; Superoxides; Uric Acid; Xanthine Oxidase | 1989 |
Characterization of free radical generation by xanthine oxidase. Evidence for hydroxyl radical generation.
Topics: Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Hydroxides; Hydroxyl Radical; Kinetics; Spin Labels; Uric Acid; Xanthine Oxidase | 1989 |
Role of xanthine oxidase in thermal injury of skin.
Topics: Animals; Burns; Edema; Enzyme Inhibitors; Free Radicals; Hydroxides; Hydroxyl Radical; Microcirculation; Oxygen; Rats; Skin; Xanthine Oxidase | 1989 |
Role of oxygen-derived free radicals in the mechanism of chronic gastric ulceration in the rat: implications for cytoprotection.
Topics: Allopurinol; Animals; Chronic Disease; Dimethyl Sulfoxide; Female; Free Radicals; Gastric Acid; Hydroxides; Hydroxyl Radical; Male; Rats; Rats, Inbred Strains; Reserpine; Stomach Ulcer; Superoxides | 1989 |
Role of superoxide and hydroxyl radicals in rat gastric mucosal injury induced by ethanol.
Topics: Allopurinol; Animals; Dimethyl Sulfoxide; Ethanol; Free Radicals; Gastric Mucosa; Hydroxides; Hydroxyl Radical; Male; Microscopy, Electron, Scanning; Rats; Rats, Inbred Strains; Superoxide Dismutase | 1989 |
Xanthine oxidase-induced injury to endothelium: role of intracellular iron and hydroxyl radical.
Topics: Animals; Deferoxamine; Endothelium, Vascular; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; Intracellular Membranes; Iron; Malondialdehyde; Xanthine Oxidase | 1989 |
Uric acid as radical scavenger and antioxidant in the heart.
Topics: Acetylcholine; Adenosine; Allopurinol; Animals; Antioxidants; Coronary Vessels; Dimethyl Sulfoxide; Free Radicals; Guinea Pigs; Heart; Hydroxides; Hydroxyl Radical; Male; Myocardium; Oxidation-Reduction; Superoxides; Uric Acid; Xanthine Oxidase | 1989 |
Carnosine, homocarnosine and anserine: could they act as antioxidants in vivo?
Topics: alpha 1-Antitrypsin; Animals; Anserine; Antioxidants; Carnosine; Dipeptides; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; Kinetics; Lipid Peroxidation; Liposomes; Microsomes, Liver; Pancreatic Elastase; Rats; Superoxides; Xanthine Oxidase | 1989 |
Non-enzymic activation of the fifth component of human complement, by oxygen radicals. Some properties of the activation product, C5b-like C5.
Topics: Complement Activation; Complement C5; Complement C5a; Complement C5b; Complement C6; Free Radicals; Humans; Hydrogen-Ion Concentration; Hydroxides; Hydroxyl Radical; Iron; Kinetics; Xanthine Oxidase | 1989 |
Oxygen radicals stimulate gallbladder glycoprotein secretion.
Topics: Animals; Free Radicals; Gallbladder; Guinea Pigs; Hydroxides; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; Mucins; Organ Culture Techniques; Oxygen; Superoxides; Xanthine Oxidase | 1989 |
Roles of histamine, complement and xanthine oxidase in thermal injury of skin.
Topics: Animals; Burns; Cimetidine; Complement Inactivator Proteins; Complement System Proteins; Cromolyn Sodium; Edema; Elapid Venoms; Endothelium, Vascular; Histamine; Histamine H1 Antagonists; Hydroxides; Hydroxyl Radical; Kinetics; Male; Radioimmunoassay; Rats; Skin; Superoxides; Uric Acid; Xanthine Oxidase | 1989 |
Superoxide dismutase-like activities of copper(II) complexes tested in serum.
Topics: Animals; Cattle; Copper; Copper Sulfate; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Hydroxides; Hydroxyl Radical; Nitroblue Tetrazolium; Oxidation-Reduction; Spin Labels; Superoxide Dismutase; Superoxides; Xanthine; Xanthine Oxidase; Xanthines | 1987 |
Alkaline phosphatase inactivation by mixed function oxidation systems.
Topics: Alkaline Phosphatase; Antioxidants; Ascorbic Acid; Catalase; Cations, Divalent; Copper; Ferric Compounds; Ferrous Compounds; Free Radicals; Glutathione; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Kinetics; Mercaptoethanol; Metals; Mixed Function Oxygenases; Oxidation-Reduction; Peroxidase; Superoxide Dismutase; Thiourea; Uric Acid; Vitamin E; Xanthine Oxidase | 1987 |
Role of xanthine oxidase inhibitor as free radical scavenger: a novel mechanism of action of allopurinol and oxypurinol in myocardial salvage.
Topics: Adenosine Triphosphate; Allopurinol; Animals; Coronary Disease; Female; Free Radicals; Heart; Hydroxides; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; Male; Myocardium; Oxypurinol; Phosphocreatine; Pyrimidines; Swine; Xanthine; Xanthine Oxidase; Xanthines | 1987 |
How relevant is the reoxidation of ferrocytochrome c by hydrogen peroxide when determining superoxide anion production?
Topics: Anions; Chromatography, Gel; Cytochrome c Group; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Kinetics; Oxidation-Reduction; Photolysis; Superoxides; Ultraviolet Rays; Uric Acid; Xanthine Oxidase | 1988 |
A possible role for free radicals in cardiac reperfusion phenomena.
Topics: Animals; Arrhythmias, Cardiac; Coronary Circulation; Coronary Disease; Free Radicals; Hydroxides; Hydroxyl Radical; Superoxides; Xanthine Oxidase | 1987 |
The influence of porphyrins on iron-catalysed generation of hydroxyl radicals.
Topics: Catalysis; Electron Spin Resonance Spectroscopy; Free Radicals; Hematoporphyrin Derivative; Hematoporphyrins; Horseradish Peroxidase; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; Iron; NADP; Porphyrins; Superoxide Dismutase; Xanthine Oxidase | 1988 |
Quantitative identification of superoxide anion as a negative inotropic species.
Topics: Animals; Catalase; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Rabbits; Superoxides; Xanthine; Xanthine Oxidase; Xanthines | 1988 |
Oxidant-induced DNA damage of target cells.
Topics: Animals; Cell Line; Cell Survival; DNA Damage; DNA Repair; Extracellular Space; Free Radicals; Glucose Oxidase; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Hypochlorous Acid; Intracellular Fluid; Macrophage Activation; Mice; Neutrophils; Rabbits; Xanthine Oxidase | 1988 |
Contracture and cell damage in calcium paradox is not caused by lipid peroxidation.
Topics: Allopurinol; Animals; Calcium; Hydroxides; Hydroxyl Radical; Lipid Peroxides; Male; Mannitol; Microscopy, Electron; Myocardial Contraction; Myocardium; Rats; Rats, Inbred Strains; Xanthine Oxidase | 1988 |
On the specificity of allopurinol and oxypurinol as inhibitors of xanthine oxidase. A pulse radiolysis determination of rate constants for reaction of allopurinol and oxypurinol with hydroxyl radicals.
Topics: Allopurinol; Free Radicals; Hydroxides; Hydroxyl Radical; Kinetics; Oxypurinol; Pyrimidines; Xanthine Oxidase | 1988 |
Inhibition of O2-.- and HO.- mediated processes by a new class of free radical scavengers: the N-acyl dehydroalanines.
Topics: Alanine; Catalase; Free Radicals; Hydroxides; Hydroxyl Radical; Indicators and Reagents; Structure-Activity Relationship; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1988 |
Potential of methylene blue to block oxygen radical generation in reperfusion injury.
Topics: Animals; Cattle; Cytochrome c Group; Female; Free Radicals; Hydroxides; Hydroxyl Radical; Kinetics; Liver; Methylene Blue; Milk; Rats; Reperfusion Injury; Superoxides; Xanthine Oxidase | 1988 |
Manganese complexes and the generation and scavenging of hydroxyl free radicals.
Topics: Ascorbic Acid; Chemical Phenomena; Chemistry; Diphosphates; DNA Damage; DNA, Bacterial; Edetic Acid; Ethylenes; Ferric Compounds; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Iron; Magnesium; Magnesium Compounds; Manganese; Mannitol; Methionine; Plasmids; Polyphosphates; Superoxides; Xanthine Oxidase | 1988 |
In vitro antioxidant properties of potential biotransformation products of salicylate, sulphasalazine and amidopyrine.
Topics: Aminopyrine; Antioxidants; Biotransformation; Free Radicals; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Luminescent Measurements; Phenols; Salicylates; Salicylic Acid; Structure-Activity Relationship; Sulfasalazine; Xanthine Oxidase | 1985 |
Excitatory amino acid release from rat hippocampal slices as a consequence of free-radical formation.
Topics: Allopurinol; Amino Acids; Animals; Aspartic Acid; Catalase; Free Radicals; Glutamates; Glutamic Acid; Hippocampus; Hydroxides; Hydroxyl Radical; Male; Mannitol; Norepinephrine; Rats; Rats, Inbred Strains; Superoxide Dismutase; Superoxides; Xanthine; Xanthine Oxidase; Xanthines | 1988 |
Ferritin and superoxide-dependent lipid peroxidation.
Topics: Animals; Catalase; Cattle; Electron Spin Resonance Spectroscopy; Ferritins; Hydroxides; Hydroxyl Radical; Iron; Lipid Peroxides; Male; Mannitol; Phospholipids; Rats; Rats, Inbred Strains; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1985 |
Role of oxygen-derived free radicals in hemorrhagic shock-induced gastric lesions in the rat.
Topics: Allopurinol; Animals; Blood Pressure; Dimethyl Sulfoxide; Free Radicals; Gastric Mucosa; Hydroxides; Hydroxyl Radical; Ischemia; Male; Rats; Rats, Inbred Strains; Shock, Hemorrhagic; Stomach Diseases; Superoxide Dismutase; Superoxides | 1985 |
Prevention of free radical-induced myocardial reperfusion injury with allopurinol.
Topics: Allopurinol; Animals; Blood Pressure; Coronary Disease; Dogs; Free Radicals; Heart Arrest, Induced; Hydrogen-Ion Concentration; Hydroxides; Hydroxyl Radical; Hypertonic Solutions; Mannitol; Myocardium; Oxidation-Reduction; Oxygen; Perfusion; Potassium; Potassium Compounds; Superoxide Dismutase; Superoxides | 1985 |
Mitoxantrone and ametantrone inhibit hydroperoxide-dependent initiation and propagation reactions in fatty acid peroxidation.
Topics: Anthraquinones; Antineoplastic Agents; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Kinetics; Linoleic Acid; Linoleic Acids; Lipid Peroxides; Micelles; Mitoxantrone; Spectrophotometry; Xanthine Oxidase | 1985 |
Comparative susceptibility of group B streptococci and Staphylococcus aureus to killing by oxygen metabolites.
Topics: Acetaldehyde; Catalase; Free Radicals; Glutathione; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Oxygen; Phagocytes; Staphylococcus aureus; Streptococcus agalactiae; Xanthine Oxidase | 1985 |
Protection of mammalian cells by o-phenanthroline from lethal and DNA-damaging effects produced by active oxygen species.
Topics: Acetaldehyde; Animals; Cell Line; Cell Survival; Chelating Agents; Chemical Phenomena; Chemistry; DNA; Electron Spin Resonance Spectroscopy; Ferrous Compounds; Fibroblasts; Free Radicals; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Iron Chelating Agents; Mice; Oxidation-Reduction; Phenanthrolines; Superoxides; Xanthine Oxidase | 1985 |
The biological oxidation of hypotaurine to taurine: hypotaurine as an antioxidant.
Topics: Animals; Antioxidants; Female; Genitalia; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Kinetics; Male; Mice; Microsomes, Liver; NADP; Oxidation-Reduction; Rats; Taurine; Xanthine Oxidase | 1985 |
Iron and xanthine oxidase catalyze formation of an oxidant species distinguishable from OH.: comparison with the Haber-Weiss reaction.
Topics: Catalysis; Deoxyribose; Ferredoxin-NADP Reductase; Formates; Free Radicals; Gamma Rays; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Iron; Oxidation-Reduction; Oxygen; Paraquat; Superoxides; Xanthine Oxidase | 1986 |
Spin-trapping of superoxide ion by a water-soluble, nitroso-aromatic spin-trap.
Topics: Benzenesulfonates; Chemical Phenomena; Chemistry; Dimethyl Sulfoxide; Electron Spin Resonance Spectroscopy; Free Radicals; Hydroxides; Hydroxyl Radical; Kinetics; Nitroso Compounds; Solutions; Spin Labels; Superoxides; Water; Xanthine; Xanthine Oxidase; Xanthines | 1986 |
Anti-oxidant effects of retinoids on inflammatory skin diseases.
Topics: Antioxidants; Dermatitis; Etretinate; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Luminescent Measurements; Neutrophils; Retinoids; Superoxides; Xanthine; Xanthine Oxidase; Xanthines; Zymosan | 1986 |
Myeloperoxidase as an effective inhibitor of hydroxyl radical production. Implications for the oxidative reactions of neutrophils.
Topics: Edetic Acid; Ferric Compounds; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Peroxidase; Xanthine Oxidase | 1986 |
The effect of oxygen-dependent antimicrobial systems on strains of Legionella pneumophila of different virulence.
Topics: Catalase; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Legionella; Peroxidase; Superoxide Dismutase; Virulence; Xanthine Oxidase | 1986 |
Inactivation of mitochondrial adenosine triphosphatase from Trypanosoma cruzi by oxygen radicals.
Topics: Adenosine Triphosphatases; Animals; Ascorbic Acid; Catalase; Cattle; Copper; Erythrocytes; Free Radicals; Hydroxides; Hydroxyl Radical; Kinetics; Liver; Mitochondria; Superoxide Dismutase; Trypanosoma cruzi; Xanthine Oxidase | 1986 |
Oxygen, ischemia and inflammation.
Topics: Animals; Bromides; Chlorides; Free Radicals; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Inflammation; Iodides; Ischemia; Microcirculation; Neutrophils; Oxygen; Peroxidase; Superoxide Dismutase; Xanthine Oxidase | 1986 |
Differential effects of the cytochrome P-450/reductase ratio on the oxidation of ethanol and the hydroxyl radical scavenging agent 2-keto-4-thiomethylbutyric acid (KMBA).
Topics: Animals; Cytochrome P-450 Enzyme System; Edetic Acid; Ethanol; Hydroxides; Hydroxyl Radical; Male; Methionine; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Rats; Rats, Inbred Strains; Xanthine Oxidase | 1986 |
Interactions of anticancer quinone drugs, aclacinomycin A, adriamycin, carbazilquinone, and mitomycin C, with NADPH-cytochrome P-450 reductase, xanthine oxidase and oxygen.
Topics: Aclarubicin; Animals; Antineoplastic Agents; Azirines; Carbazilquinone; Doxorubicin; Drug Interactions; Electron Spin Resonance Spectroscopy; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Kinetics; Mitomycin; Mitomycins; NADPH-Ferrihemoprotein Reductase; Naphthacenes; Oxygen; Spectrophotometry, Ultraviolet; Superoxides; Xanthine Oxidase | 1986 |
Spin trapping of superoxide and hydroxyl radicals with substituted pyrroline 1-oxides.
Topics: Animals; Cattle; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Glutathione Peroxidase; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Indicators and Reagents; Kinetics; Male; Portal Vein; Rats; Rats, Inbred Strains; Spin Labels; Structure-Activity Relationship; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1986 |
Hydroxyl radical formation and iron-binding proteins. Stimulation by the purple acid phosphatases.
Topics: Acid Phosphatase; Animals; Cattle; Chemical Phenomena; Chemistry; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; Isoenzymes; Lactoferrin; Metalloproteins; Oxidation-Reduction; Spleen; Superoxides; Tartrate-Resistant Acid Phosphatase; Transferrin; Xanthine Oxidase | 1987 |
Hydroxyl radical scavenging action of tinoridine.
Topics: Adenosine Diphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytochrome c Group; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Iron; Lipid Peroxides; Male; Microsomes, Liver; Oxidation-Reduction; Pyridines; Rats; Rats, Inbred Strains; Superoxide Dismutase; Thienopyridines; Xanthine Oxidase | 1986 |
Allopurinol and oxypurinol are hydroxyl radical scavengers.
Topics: Allopurinol; Ascorbic Acid; Chromatography, High Pressure Liquid; Deoxyribose; Ferric Compounds; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Hypochlorous Acid; Kinetics; Oxypurinol; Peroxidase; Pyrimidines; Xanthine Oxidase | 1987 |
Superoxide radical initiates the autoxidation of dihydroxyacetone.
Topics: Catalase; Chelating Agents; Dihydroxyacetone; Free Radicals; Hydrogen-Ion Concentration; Hydroxides; Hydroxyl Radical; Kinetics; Oxidation-Reduction; Superoxide Dismutase; Superoxides; Trioses; Xanthine Oxidase | 1987 |
Production of 4-hydroxypyrazole from the interaction of the alcohol dehydrogenase inhibitor pyrazole with hydroxyl radical.
Topics: Alcohol Dehydrogenase; Animals; Free Radicals; Hydroxides; Hydroxyl Radical; Kinetics; Male; Microsomes, Liver; Pyrazoles; Rats; Rats, Inbred Strains; Xanthine Oxidase | 1987 |
Decreased hydroxyl radical generation from polymorphonuclear leucocytes in the presence of D-penicillamine and thiopronine.
Topics: Adult; Amino Acids, Sulfur; Cell-Free System; Free Radicals; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Hydroxylation; In Vitro Techniques; Neutrophils; Penicillamine; Tiopronin; Xanthine; Xanthine Oxidase; Xanthines | 1987 |
The ability of scavengers to distinguish OH. production in the iron-catalyzed Haber-Weiss reaction: comparison of four assays for OH.
Topics: Benzoates; Benzoic Acid; Catalysis; Deoxyribose; Formates; Free Radicals; Hydroxides; Hydroxyl Radical; Iron; Methionine; Oxidation-Reduction; Xanthine Oxidase | 1987 |
Mechanism of kainate toxicity to cerebellar neurons in vitro is analogous to reperfusion tissue injury.
Topics: Allopurinol; Animals; Cell Survival; Cells, Cultured; Cerebellum; Endopeptidases; Hydroxides; Hydroxyl Radical; Ischemia; Kainic Acid; Mannitol; Mice; NADPH Dehydrogenase; Nervous System Diseases; Neurons; Perfusion; Protease Inhibitors; Serine Endopeptidases; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1987 |
In vivo and in vitro oxidative biotransformation of dimethylformamide in rat.
Topics: Animals; Ascorbic Acid; Biotransformation; Dimethylformamide; Edetic Acid; Ferric Compounds; Formamides; Formates; Free Radicals; Hydroxides; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Male; Microsomes, Liver; Oxidation-Reduction; Rats; Rats, Inbred Strains; Xanthine Oxidase | 1984 |
Oxygen radicals: effects on intestinal vascular permeability.
Topics: Animals; Capillaries; Cats; Dimethyl Sulfoxide; Female; Free Radicals; Hydroxides; Hydroxyl Radical; Ileum; Lymph; Male; Regional Blood Flow; Superoxide Dismutase; Superoxides; Xanthine; Xanthine Oxidase; Xanthines | 1984 |
Dissociation of the inhibitory effect of dapsone on the generation of oxygen intermediates--in comparison with that of colchicine and various scavengers.
Topics: Colchicine; Dapsone; Free Radicals; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Luminescent Measurements; Neutrophils; Oxygen; Superoxides; Xanthine Oxidase | 1984 |
Evidence for the participation of superoxide anion radical in altering the adhesive interaction between granulocytes and endothelium, in vivo.
Topics: Animals; Cell Adhesion; Cheek; Cricetinae; Endothelium; Free Radicals; Granulocytes; Hydroxides; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; Male; Mesocricetus; Superoxide Dismutase; Superoxides; Veins; Venules; Xanthine Oxidase | 1982 |
Streptonigrin-induced deoxyribose degradation: inhibition by superoxide dismutase, hydroxyl radical scavengers and iron chelators.
Topics: Catalase; Chelating Agents; Deoxyribose; Hydroxides; Hydroxyl Radical; Iron; Streptonigrin; Superoxide Dismutase; Xanthine Oxidase | 1984 |
Hydroxyl radical production from hydrogen peroxide and enzymatically generated paraquat radicals: catalytic requirements and oxygen dependence.
Topics: Anaerobiosis; Chemical Phenomena; Chemistry; Deoxyribose; Edetic Acid; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Oxygen; Paraquat; Pentetic Acid; Superoxide Dismutase; Xanthine Oxidase | 1984 |
Xanthine oxidase induced depolymerization of hyaluronic acid in the presence of ferritin.
Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Deferoxamine; Edetic Acid; Ferritins; Hyaluronic Acid; Hydroxides; Hydroxyl Radical; Superoxides; Viscosity; Xanthine Oxidase | 1984 |
Role of oxygen radicals in ocular inflammation and cellular damage.
Topics: Animals; Anterior Chamber; Copper; Eye; Eye Diseases; Fatty Acids, Unsaturated; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Inflammation; Leukocytes; Lipid Peroxides; Oxidation-Reduction; Oxygen; Rabbits; Superoxides; Xanthine Oxidase | 1984 |
Evidence for participation of hydroxyl radical in increased microvascular permeability.
Topics: Animals; Capillary Permeability; Catalase; Cricetinae; Dextrans; Dimethyl Sulfoxide; Free Radicals; Hydroxides; Hydroxyl Radical; Inflammation; Methionine; Superoxide Dismutase; Xanthine Oxidase | 1980 |
Production of formaldehyde during metabolism of dimethyl sulfoxide by hydroxyl radical generating systems.
Topics: Animals; Ascorbic Acid; Chemical Phenomena; Chemistry; Dimethyl Sulfoxide; Edetic Acid; Formaldehyde; Free Radicals; Hydroxides; Hydroxyl Radical; Iron; Kinetics; Male; Microsomes, Liver; Rats; Rats, Inbred Strains; Xanthine Oxidase | 1981 |
Superoxide-dependent formation of hydroxyl radicals: detection of hydroxyl radicals by the hydroxylation of aromatic compounds.
Topics: Chemistry, Organic; Chromatography, Gas; Colorimetry; Free Radicals; Hydroxides; Hydroxyl Radical; Hydroxylation; Hypoxanthine; Hypoxanthines; Organic Chemistry Phenomena; Oxygen; Phenols; Salicylates; Superoxides; Xanthine Oxidase | 1981 |
Enhanced production of hydroxyl radicals by the xanthine-xanthine oxidase reaction in the presence of lactoferrin.
Topics: Animals; Cattle; Electron Spin Resonance Spectroscopy; Female; Free Radicals; Hydroxides; Hydroxyl Radical; Kinetics; Lactoferrin; Lactoglobulins; Milk; Superoxides; Swine; Xanthine Oxidase; Xanthines | 1982 |
Effect of CuSO4 and Cu(II)(Gly)2 on some indirect assays for superoxide dismutase activity.
Topics: Animals; Copper; Copper Sulfate; Cytochrome c Group; Dianisidine; Free Radicals; Glycine; Hydroxides; Hydroxyl Radical; Light; Nitroblue Tetrazolium; Organometallic Compounds; Oxidation-Reduction; Rats; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1982 |
An investigation into the role of hydroxyl radical in xanthine oxidase-dependent lipid peroxidation.
Topics: Animals; Cattle; Erythrocytes; Free Radicals; Hydroxides; Hydroxyl Radical; Iron; Kinetics; Lipid Peroxides; Liposomes; Liver; Superoxide Dismutase; Xanthine Oxidase | 1982 |
Pyrazole and 4-methylpyrazole inhibit oxidation of ethanol and dimethyl sulfoxide by hydroxyl radicals generated from ascorbate, xanthine oxidase, and rat liver microsomes.
Topics: Animals; Ascorbic Acid; Dimethyl Sulfoxide; Ethanol; Fomepizole; Free Radicals; Hydroxides; Hydroxyl Radical; Kinetics; Male; Microsomes, Liver; Oxidation-Reduction; Pyrazoles; Rats; Rats, Inbred Strains; Xanthine Oxidase | 1982 |
Iodination catalyzed by the xanthine oxidase system: role of hydroxyl radicals.
Topics: Acetaldehyde; Chlorides; Edetic Acid; Ferrous Compounds; Free Radicals; Hydroxides; Hydroxyl Radical; Iodides; Peroxidase; Peroxidases; Serum Albumin; Xanthine Oxidase | 1982 |
The role of the superoxide and hydroxyl radicals in the degradation of DNA and deoxyribose induced by a copper-phenanthroline complex.
Topics: Biotransformation; Deoxyribose; DNA; Free Radicals; Hydroxides; Hydroxyl Radical; Mercaptoethanol; NAD; Oxygen; Phenanthrolines; Superoxides; Thiobarbiturates; Xanthine Oxidase | 1982 |
The role of superoxide and hydroxyl radicals in phospholipid peroxidation catalysed by iron salts.
Topics: Animals; Catalase; Cattle; Erythrocytes; Hydroxides; Hydroxyl Radical; Iron; Lipid Peroxides; Liver; Oxygen; Phospholipids; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1982 |
Styrene oxidation to styrene oxide by hydroxyl radicals produced during reaction of xanthine with xanthine oxidase in the presence of Fe3+.
Topics: Chemical Phenomena; Chemistry; Epoxy Compounds; Ethers, Cyclic; Ferric Compounds; Free Radicals; Hydroxides; Hydroxyl Radical; Oxidation-Reduction; Styrene; Styrenes; Xanthine; Xanthine Oxidase; Xanthines | 1983 |
Leukotriene B4, C4, D4 and E4 inactivation by hydroxyl radicals.
Topics: Animals; Cattle; Female; Free Radicals; Hydroxides; Hydroxyl Radical; Kinetics; Leukotriene B4; Leukotriene E4; Milk; SRS-A; Structure-Activity Relationship; Xanthine Oxidase | 1983 |
Superoxide-dependent formation of hydroxyl radical catalyzed by transferrin.
Topics: Animals; Catalysis; Cattle; Chemical Phenomena; Chemistry; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; Hydroxylation; Hypoxanthines; Oxygen; Superoxides; Transferrin; Xanthine Oxidase | 1983 |
Ischemia-induced vascular changes: role of xanthine oxidase and hydroxyl radicals.
Topics: Allopurinol; Animals; Cats; Dimethyl Sulfoxide; Free Radicals; Hydroxides; Hydroxyl Radical; Ileum; Ischemia; Microcirculation; Xanthine Oxidase | 1983 |
Production of formaldehyde and acetone by hydroxyl-radical generating systems during the metabolism of tertiary butyl alcohol.
Topics: Acetone; Animals; Ascorbic Acid; Butanols; Chemical Phenomena; Chemistry; Cytochrome P-450 Enzyme System; Edetic Acid; Formaldehyde; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Iron; Male; Microsomes, Liver; Models, Chemical; Oxidation-Reduction; Rats; Rats, Inbred Strains; tert-Butyl Alcohol; Xanthine; Xanthine Oxidase; Xanthines | 1983 |
Mitomycin C-induced deoxyribose degradation inhibited by superoxide dismutase. A reaction involving iron, hydroxyl and semiquinone radicals.
Topics: Animals; Benzoquinones; Cattle; Deferoxamine; Deoxyribose; Edetic Acid; Humans; Hydroxides; Hydroxyl Radical; Iron; Mitomycin; Mitomycins; Pentetic Acid; Quinones; Superoxide Dismutase; Xanthine Oxidase | 1984 |
Free radicals-induced changes in mesenteric microvascular dimensions in the anesthetized cat.
Topics: Anesthesia; Animals; Cats; Female; Free Radicals; Hydrogen-Ion Concentration; Hydroxides; Hydroxyl Radical; Lipid Peroxides; Male; Mesentery; Microcirculation; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1983 |
Iron-catalyzed hydroxyl radical formation. Stringent requirement for free iron coordination site.
Topics: Chelating Agents; Free Radicals; Hydroxides; Hydroxyl Radical; Iron; Kinetics; Magnetic Resonance Spectroscopy; Spectrophotometry; Xanthine Oxidase | 1984 |
Myocardial alterations due to free-radical generation.
Topics: Animals; Cattle; Free Radicals; Heart Ventricles; Hydroxides; Hydroxyl Radical; Liver; Male; Microscopy, Electron; Mitochondria, Heart; Myocardium; Rabbits; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1984 |
The role of iron chelates in hydroxyl radical production by rat liver microsomes, NADPH-cytochrome P-450 reductase and xanthine oxidase.
Topics: Animals; Catalase; Catalysis; Free Radicals; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Iron Chelating Agents; Male; Methionine; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Rats; Rats, Inbred Strains; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1984 |
Inactivation of xanthine oxidase by oxidative radical attack.
Topics: Hydrogen-Ion Concentration; Hydroxyl Radical; Oxidation-Reduction; Pulse Radiolysis; Xanthine Oxidase | 1995 |
Effect of zinc on superoxide-dependent hydroxyl radical production in vitro.
Topics: Copper; Edetic Acid; Ethylenes; Humans; Hydroxyl Radical; Indicators and Reagents; Iron; Ligands; Methionine; Plasma; Superoxide Dismutase; Superoxides; Xanthine Oxidase; Zinc | 1993 |
Evaluation of the antioxidant actions of ferulic acid and catechins.
Topics: Antioxidants; Bleomycin; Catechin; Coumaric Acids; Cytochrome c Group; DNA Damage; Free Radicals; Hydroxyl Radical; Hypochlorous Acid; Hypoxanthine; Hypoxanthines; Lipid Peroxidation; Liposomes; Peroxides; Superoxides; Xanthine Oxidase | 1993 |
Novel 21-aminosteroidlike compounds prevent iron-induced free radical-mediated injury to vascular endothelial cells.
Topics: Allopurinol; Animals; Antimetabolites; Antioxidants; Aorta; Butylated Hydroxytoluene; Cattle; Cell Count; Cell Membrane; Cell Survival; Chromans; Deferoxamine; Dogs; Endothelium, Vascular; Free Radical Scavengers; Free Radicals; Hydroxyl Radical; Iron; Iron Chelating Agents; Lipid Peroxidation; Piperazines; Pregnatrienes; Probucol; Pulmonary Artery; Siderophores | 1995 |
Singlet oxygen-trapping reaction as a method of (1)O2 detection: role of some reducing agents.
Topics: Ascorbic Acid; Cations; Cyclic N-Oxides; Deferoxamine; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Iron; Oxidation-Reduction; Oxygen; Piperidones; Reactive Oxygen Species; Triacetoneamine-N-Oxyl; Ultraviolet Rays; Xanthine Oxidase | 1995 |
Antioxidative activity of 5,6,7,8-tetrahydrobiopterin and its inhibitory effect on paraquat-induced cell toxicity in cultured rat hepatocytes.
Topics: Animals; Antioxidants; Biopterins; Cell Survival; Cells, Cultured; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Hydroxyl Radical; Lipid Peroxides; Liver; Luminescent Measurements; Macrophages; Male; Paraquat; Rats; Rats, Wistar; Superoxides; Tetradecanoylphorbol Acetate; Xanthine; Xanthine Oxidase; Xanthines | 1995 |
Adenosines scavenged hydroxyl radicals and prevented posttraumatic epilepsy.
Topics: 2-Chloroadenosine; Adenosine; Animals; Chlorides; Cyclic N-Oxides; Electroencephalography; Electron Spin Resonance Spectroscopy; Epilepsy, Post-Traumatic; Ferric Compounds; Free Radical Scavengers; Free Radicals; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; Male; Rats; Rats, Sprague-Dawley; Spin Labels; Superoxides; Xanthine Oxidase | 1995 |
Modulation of N-methyl-D-aspartate receptors by hydroxyl radicals in rat cortical neurons in vitro.
Topics: Animals; Anions; Cerebral Cortex; Dithiothreitol; Hydrogen Peroxide; Hydroxyl Radical; Mannitol; Neurons; Oxidation-Reduction; Rats; Receptors, N-Methyl-D-Aspartate; Spectrophotometry; Superoxides; Xanthine; Xanthine Oxidase; Xanthines | 1995 |
An in vitro EPR study of the free-radical scavenging actions of the lazaroid antioxidants U-74500A and U-78517F.
Topics: Antioxidants; Chromans; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Ferrous Compounds; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; Piperazines; Pregnatrienes; Superoxides; Xanthine Oxidase | 1995 |
Production of hydroxyl radical by iron(III)-anthraquinone complexes through self-reduction and through reductive activation by the xanthine oxidase/hypoxanthine system.
Topics: Antibiotics, Antineoplastic; Cyclic N-Oxides; Doxorubicin; Electron Spin Resonance Spectroscopy; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; Iron; Kinetics; Models, Theoretical; Molecular Structure; Organometallic Compounds; Oxidation-Reduction; Spin Labels; Structure-Activity Relationship; Xanthine Oxidase | 1995 |
Detection by ESR of DMPO hydroxyl adduct formation from islets of Langerhans.
Topics: Animals; Catalase; Cells, Cultured; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Iron; Islets of Langerhans; Male; Oxypurinol; Protein Denaturation; Rats; Rats, Wistar; Superoxide Dismutase; Xanthine Oxidase | 1995 |
Singlet oxygen generation in the superoxide reaction.
Topics: Azides; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen Peroxide; Hydroxyl Radical; Oxygen; Singlet Oxygen; Sodium Azide; Spin Labels; Superoxide Dismutase; Superoxides; Xanthine; Xanthine Oxidase; Xanthines | 1995 |
Oxidation of DMSO and methanesulfinic acid by the hydroxyl radical.
Topics: Chromatography, High Pressure Liquid; Dimethyl Sulfoxide; False Negative Reactions; Hydroxyl Radical; Oxidation-Reduction; Sulfinic Acids; Xanthine; Xanthine Oxidase; Xanthines | 1995 |
Effect of nitric oxide and cell redox status on the regulation of endothelial cell xanthine dehydrogenase.
Topics: Animals; Catalase; Cattle; Cells, Cultured; Endothelium, Vascular; Extracellular Space; Free Radical Scavengers; Glutathione; Hydrogen Peroxide; Hydroxyl Radical; Intracellular Membranes; Nitric Oxide; Oxidation-Reduction; Oxygen; Pulmonary Artery; Vitamin K; Xanthine Dehydrogenase; Xanthine Oxidase | 1995 |
Antioxidant action of Ginkgo biloba extract EGb 761.
Topics: Antioxidants; Free Radical Scavengers; Free Radicals; Gamma Rays; Ginkgo biloba; Hydroxyl Radical; Indicators and Reagents; Kinetics; Liposomes; Nitric Oxide; Oxyhemoglobins; Peroxides; Plant Extracts; Plants, Medicinal; Spectrophotometry; Superoxides; Water; Xanthine Oxidase | 1994 |
Differential effects of superoxide, hydrogen peroxide, and hydroxyl radical on intracellular calcium in human endothelial cells.
Topics: Calcium; Cells, Cultured; Endothelium, Vascular; Homeostasis; Humans; Hydrogen Peroxide; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; Oxidative Stress; Phenanthrolines; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1995 |
Studies on the inhibitory effects of curcumin and eugenol on the formation of reactive oxygen species and the oxidation of ferrous iron.
Topics: Curcumin; Deoxyribose; Eugenol; Hydroxyl Radical; Iron; Lipid Peroxidation; Oxidation-Reduction; Reactive Oxygen Species; Superoxides; Xanthine; Xanthine Oxidase; Xanthines | 1994 |
Antioxidative effects of a processed grain food.
Topics: Animals; Antioxidants; Brain; Edible Grain; Electron Spin Resonance Spectroscopy; Fermentation; Free Radical Scavengers; Glycine max; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; Lipid Peroxidation; Male; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Spin Labels; Superoxides; Tea; Thiobarbituric Acid Reactive Substances; Xanthine Oxidase | 1994 |
Oxidation pathways for the intracellular probe 2',7'-dichlorofluorescein.
Topics: Fluoresceins; Hydrogen Peroxide; Hydroxyl Radical; In Vitro Techniques; Iron; Oxidation-Reduction; Oxidative Stress; Superoxides; Xanthine Oxidase | 1994 |
Use of M4PO and oxygen-17 in the study on hydroxyl radical generation in the hypoxanthine-xanthine oxidase reaction.
Topics: Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; Isotope Labeling; Kinetics; Oxygen Isotopes; Spin Labels; Xanthine Oxidase | 1994 |
A potent antioxidant, SB209995, inhibits oxygen-radical-mediated lipid peroxidation and cytotoxicity.
Topics: Animals; Antioxidants; Brain; Carbazoles; Carvedilol; Cattle; Cells, Cultured; Endothelium, Vascular; Free Radicals; Humans; Hydroxyl Radical; Lipid Peroxidation; Lipoproteins, LDL; Oxygen; Propanolamines; Rats; Superoxides; Xanthine Oxidase | 1994 |
Role of polymorphonuclear leucocytes and oxygen-derived free radicals in the formation of gastric lesions induced by HCl/ethanol, and a possible mechanism of protection by anti-ulcer polysaccharide.
Topics: Allopurinol; Animals; Anti-Ulcer Agents; Carrageenan; Cattle; Cyclophosphamide; Ethanol; Free Radical Scavengers; Gastric Mucosa; Hydrochloric Acid; Hydroxides; Hydroxyl Radical; Male; Mice; Mice, Inbred ICR; Neutrophils; Pectins; Rabbits; Reactive Oxygen Species; Stomach Ulcer; Superoxides | 1993 |
Inhibition of the iron-catalysed formation of hydroxyl radicals by nitrosouracil derivatives: protection of mitochondrial membranes against lipid peroxidation.
Topics: Animals; Catalase; Cattle; Deoxyribose; Hydrogen Peroxide; Hydroxyl Radical; Intracellular Membranes; Iron; Lipid Peroxidation; Mitochondria, Heart; Nitroso Compounds; Oxygen; Thiobarbituric Acid Reactive Substances; Uracil; Xanthine; Xanthine Oxidase; Xanthines | 1993 |
Angiotensin converting enzyme inhibitors as oxygen free radical scavengers.
Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Catalase; Chlorides; Deoxyribose; Dimethyl Sulfoxide; Edetic Acid; Enalaprilat; Ferric Compounds; Free Radical Scavengers; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; Lisinopril; Luminescent Measurements; Superoxide Dismutase; Xanthine Oxidase | 1993 |
Mechanisms of copper- and iron-dependent oxidative modification of human low density lipoprotein.
Topics: Azoles; Copper; Glutathione; Humans; Hydrogen Peroxide; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; Iron; Isoindoles; Lipid Peroxidation; Lipoproteins, LDL; Organoselenium Compounds; Oxidation-Reduction; Superoxides; Xanthine Oxidase | 1993 |
Effect of acetyl-L-carnitine on lipid peroxidation and xanthine oxidase activity in rat skeletal muscle.
Topics: Acetylcarnitine; Animals; Dimethyl Sulfoxide; Hydroxyl Radical; Kinetics; Lipid Peroxidation; Male; Malondialdehyde; Microsomes; Muscles; Rats; Rats, Wistar; Xanthine Dehydrogenase; Xanthine Oxidase | 1993 |
Vanadate-mediated hydroxyl radical generation from superoxide radical in the presence of NADH: Haber-Weiss vs Fenton mechanism.
Topics: Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Hydroxyl Radical; NAD; Superoxides; Vanadates; Xanthine; Xanthine Oxidase; Xanthines | 1993 |
Characteristic bleaching profiles of cyanine dyes depending on active oxygen species in the controlled Fenton reaction.
Topics: Coloring Agents; Ferric Compounds; Ferrous Compounds; Free Radicals; Hydrogen Peroxide; Hydroxyl Radical; Reactive Oxygen Species; Superoxides; Thiazoles; Xanthine Oxidase | 1993 |
Superoxide dismutase (SOD)-catalase conjugates. Role of hydrogen peroxide and the Fenton reaction in SOD toxicity.
Topics: Animals; Catalase; Chromatography, Gel; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Heart; Heart Rate; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Iron; Metabolic Clearance Rate; Rats; Rats, Sprague-Dawley; Spin Labels; Superoxide Dismutase; Systole; Xanthine Oxidase | 1993 |
Role of endothelium for tissue damage by active oxygen radicals in heart-lung transplantation.
Topics: Allopurinol; Animals; Dogs; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; Free Radicals; Granulocytes; Heart-Lung Transplantation; Hydroxides; Hydroxyl Radical; Luminescent Measurements; Oxygen; Reperfusion Injury | 1993 |
The hydrolysis product of ICRF-187 promotes iron-catalysed hydroxyl radical production via the Fenton reaction.
Topics: Ascorbic Acid; Chelating Agents; Deoxyribose; Dimethyl Sulfoxide; Doxorubicin; Edetic Acid; Ethylenediamines; Ferric Compounds; Glycine; Hydrogen Peroxide; Hydrolysis; Hydroxides; Hydroxyl Radical; Iron; Kinetics; Oxidation-Reduction; Paraquat; Razoxane; Superoxides; Thiobarbituric Acid Reactive Substances; Xanthine Oxidase | 1993 |
The oxidation of alpha-tocopherol in human low-density lipoprotein by the simultaneous generation of superoxide and nitric oxide.
Topics: Acetaldehyde; Catalase; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; Lipoproteins, LDL; Molsidomine; Nitric Oxide; Nitrogen Dioxide; Oxidation-Reduction; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Superoxides; Thiobarbiturates; Vitamin E; Xanthine Oxidase | 1993 |
Redox cycling of MPP+: evidence for a new mechanism involving hydride transfer with xanthine oxidase, aldehyde dehydrogenase, and lipoamide dehydrogenase.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Aldehyde Dehydrogenase; Dihydrolipoamide Dehydrogenase; Electron Spin Resonance Spectroscopy; Hydroxides; Hydroxyl Radical; NAD; Oxidation-Reduction; Photolysis; Superoxides; Ultraviolet Rays; Xanthine Oxidase | 1993 |
Acrolein-induced oxygen radical formation.
Topics: Acrolein; Aldehyde Dehydrogenase; Electron Spin Resonance Spectroscopy; Free Radicals; Glutathione; Hydroxides; Hydroxyl Radical; Lipid Peroxidation; Oxidation-Reduction; Oxygen; Superoxides; Xanthine Oxidase | 1993 |
Inhibition of hydroxyl radical formation by human tears.
Topics: Eye Proteins; Female; Humans; Hydrogen Peroxide; Hydroxyl Radical; Hydroxylation; Male; Superoxides; Tears; Xanthine; Xanthine Oxidase; Xanthines | 1987 |
Characterization of the radical trapping activity of a novel series of cyclic nitrone spin traps.
Topics: Animals; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Hydroxyl Radical; Iron; Isoquinolines; Lipid Peroxidation; Liposomes; Mice; Models, Molecular; Models, Structural; Nitrogen Oxides; Oxidative Stress; Spin Labels; Structure-Activity Relationship; Superoxides; Xanthine Oxidase | 1996 |
Adenosine deaminase inhibition prevents free radical-mediated injury in the postischemic heart.
Topics: Adenine; Adenine Nucleotides; Adenosine Deaminase Inhibitors; Animals; Coronary Circulation; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Female; Free Radicals; Hydroxyl Radical; Myocardial Ischemia; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxides; Xanthine Oxidase | 1996 |
Mechanism of hydrogen peroxide and hydroxyl free radical-induced intracellular acidification in cultured rat cardiac myoblasts.
Topics: Acidosis; Acids; Adenosine Triphosphate; Animals; Calcium; Carrier Proteins; Cells, Cultured; Hydrogen Peroxide; Hydrolysis; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; Intracellular Membranes; Male; Myocardium; Rats; Rats, Wistar; Reactive Oxygen Species; Xanthine Oxidase | 1996 |
Oxidation of caffeine and related methylxanthines in ascorbate and polyphenol-driven Fenton-type oxidations.
Topics: Animals; Ascorbic Acid; Caffeine; Catalase; Cattle; Chromatography, High Pressure Liquid; Edetic Acid; Ferrous Compounds; Hydroxyl Radical; Kinetics; Liver; Mass Spectrometry; Molecular Structure; Oxidation-Reduction; Phenols; Purines; Superoxide Dismutase; Xanthine; Xanthine Oxidase; Xanthines | 1996 |
Inhibition of human neutrophil binding to hydrogen peroxide-treated endothelial cells by cAMP and hydroxyl radical scavengers.
Topics: 1-Methyl-3-isobutylxanthine; Analysis of Variance; Bucladesine; Cell Adhesion; Cells, Cultured; Cyclic AMP; Deferoxamine; Endothelium, Vascular; Free Radical Scavengers; Glutathione; Humans; Hydrogen Peroxide; Hydroxyl Radical; Hypoxanthine; Isoproterenol; Neutrophils; Pentoxifylline; Tetradecanoylphorbol Acetate; Thrombin; Transferrin; Umbilical Veins; Xanthine Oxidase | 1996 |
A high performance liquid chromatography system for quantification of hydroxyl radical formation by determination of dihydroxy benzoic acids.
Topics: Chromatography, High Pressure Liquid; Colorectal Neoplasms; Humans; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Hypoxanthine; Iron; Oxidation-Reduction; Reactive Oxygen Species; Salicylates; Salicylic Acid; Xanthine Oxidase | 1996 |
Effect of cystathionine as a scavenger of superoxide generated from human leukocytes or derived from xanthine oxidase in vitro.
Topics: Cystathionine; Erythrocyte Membrane; Free Radical Scavengers; Humans; Hydroxyl Radical; Imidazoles; Leukocytes; Lipid Peroxidation; Pyrazines; Superoxides; Xanthine Oxidase | 1996 |
An artificial CuII complex with intriguing oxygen radical-quenching profile. X-ray structure, cytochrome c assay, and ESR study.
Topics: Copper; Crystallography, X-Ray; Cytochrome c Group; Electron Spin Resonance Spectroscopy; Free Radicals; Hydroxyl Radical; Models, Molecular; Oxygen; Xanthine Oxidase | 1996 |
In vitro susceptibility of Mycobacterium leprae to oxygen-mediated damage.
Topics: Animals; Antioxidants; Armadillos; Catalase; Cell Line; Glutathione Peroxidase; Hydrogen Peroxide; Hydroxyl Radical; Lactoperoxidase; Mycobacterium leprae; Oxidants; Potassium Iodide; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1996 |
Direct effects of intraperilymphatic reactive oxygen species generation on cochlear function.
Topics: Action Potentials; Analysis of Variance; Animals; Antidotes; Auditory Threshold; Catalase; Cochlea; Cochlear Microphonic Potentials; Deferoxamine; Enzyme Inhibitors; Guinea Pigs; Hydrogen Peroxide; Hydroxyl Radical; Perilymph; Potassium Cyanide; Reactive Oxygen Species; Spectrophotometry, Ultraviolet; Superoxide Dismutase; Superoxides; Xanthine; Xanthine Oxidase; Xanthines | 1996 |
Natural polyhydroxylated compounds as inhibitors of xanthine oxidase.
Topics: Benzofurans; Enzyme Inhibitors; Flavonoids; Hydroxyl Radical; Molecular Conformation; Structure-Activity Relationship; Xanthine Oxidase | 1996 |
Tempace and troxyl-novel synthesized 2,2,6,6-tetramethylpiperidine derivatives as antioxidants and radioprotectors.
Topics: Antioxidants; Cobalt Radioisotopes; Cyclic N-Oxides; Deoxyribose; Dose-Response Relationship, Drug; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Iron; Oxidation-Reduction; Piperidines; Radiation-Protective Agents; Spin Labels; Superoxide Dismutase; Superoxides; Thiobarbituric Acid Reactive Substances; Xanthine; Xanthine Oxidase; Xanthines | 1996 |
Role of rebamipide on induction of heat-shock proteins and protection against reactive oxygen metabolite-mediated cell damage in cultured gastric mucosal cells.
Topics: Alanine; Animals; Anti-Ulcer Agents; Catalase; Cell Death; Cells, Cultured; Free Radical Scavengers; Gastric Mucosa; HSP70 Heat-Shock Proteins; Hydroxyl Radical; Hypoxanthine; Lipid Peroxidation; Quinolones; Rabbits; Reactive Oxygen Species; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Xanthine Oxidase | 1997 |
Peroxynitrite induces the conversion of xanthine dehydrogenase to oxidase in rabbit liver.
Topics: Animals; Cytosol; Dimethyl Sulfoxide; Dithiothreitol; Dose-Response Relationship, Drug; Free Radical Scavengers; Hydroxyl Radical; Kinetics; Liver; Male; Mannitol; Nitrates; Rabbits; Xanthine Dehydrogenase; Xanthine Oxidase | 1997 |
Synthesis of guanidinosuccinate from argininosuccinate and reactive oxygen in vitro.
Topics: Argininosuccinic Acid; Dimethyl Sulfoxide; Guanidines; Hydroxyl Radical; Reactive Oxygen Species; Succinates; Superoxides; Xanthine Oxidase | 1996 |
Effects of sucralfate on acute gastric mucosal injury and gastric ulcer induced by ischemia-reperfusion in rats.
Topics: Animals; Anti-Ulcer Agents; Erythrocyte Membrane; Gastric Mucosa; Hydroxyl Radical; Leukocytes; Lipid Peroxides; Male; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Stomach Ulcer; Sucralfate; Superoxides; Thiobarbituric Acid Reactive Substances; Xanthine Oxidase | 1997 |
Increased generation of hydrogen peroxide possibly from mitochondrial respiratory chain after UVB irradiation of murine fibroblasts.
Topics: Allopurinol; Animals; Catalase; Cells, Cultured; Chelating Agents; Electron Transport; Fibroblasts; Hydrogen Peroxide; Hydroxyl Radical; Mice; Mice, Inbred ICR; Mitochondria; Skin; Superoxides; Thenoyltrifluoroacetone; Ultraviolet Rays; Xanthine Oxidase | 1997 |
Protective effect of diltiazem on myocardial ischemic injury associated with .OH generation.
Topics: Allopurinol; Animals; Calcium Channel Blockers; Diltiazem; Heart Rate; Hydroxybenzoates; Hydroxyl Radical; Male; Myocardial Reperfusion Injury; Norepinephrine; Rats; Rats, Wistar; Salicylates; Salicylic Acid; Xanthine; Xanthine Oxidase; Xanthines | 1997 |
Stimulated human leukocytes cause activating mutations in the K-ras protooncogene.
Topics: 3T3 Cells; 8-Hydroxy-2'-Deoxyguanosine; Animals; Deoxyguanosine; DNA Damage; DNA, Neoplasm; Genes, ras; Humans; Hydroxyl Radical; Leukocytes; Lymphocyte Activation; Mice; Mutation; Plasmids; Purines; ras Proteins; Transfection; Xanthine Oxidase | 1997 |
Mechanisms of active oxygen species reduction by non-steroidal anti-inflammatory drugs.
Topics: Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Electron Spin Resonance Spectroscopy; Horseradish Peroxidase; Hydrogen Peroxide; Hydroxyl Radical; Hypoxanthine; Kinetics; Oxidation-Reduction; Reactive Oxygen Species; Spectrophotometry; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1997 |
Reactive oxygen species cause direct damage of Engelbreth-Holm-Swarm matrix.
Topics: Animals; Biopolymers; Collagen; Cross-Linking Reagents; Dimerization; Dose-Response Relationship, Drug; Extracellular Matrix; Extracellular Matrix Proteins; Hydrogen Peroxide; Hydroxyl Radical; Iron; Laminin; Membrane Glycoproteins; Metalloendopeptidases; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Oxidation-Reduction; Reactive Oxygen Species; Tyrosine; Xanthine Oxidase | 1997 |
Hydroxyl radical-induced decline in motility and increase in lipid peroxidation and DNA modification in human sperm.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenosine Diphosphate; Deoxyguanosine; DNA; Ferrous Compounds; Humans; Hydrogen Peroxide; Hydroxyl Radical; Kinetics; Lipid Peroxidation; Male; Malondialdehyde; Sperm Motility; Spermatozoa; Xanthine; Xanthine Oxidase | 1997 |
Differential effect of hydrogen peroxide and superoxide anion on apoptosis and proliferation of vascular smooth muscle cells.
Topics: Animals; Anions; Apoptosis; Cell Division; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Ferrous Compounds; Hydrogen Peroxide; Hydroxyl Radical; Male; Muscle, Smooth, Vascular; Oxidants; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Superoxides; Xanthine; Xanthine Oxidase | 1997 |
2-2'-Pyridylisatogen, a selective allosteric modulator of P2 receptors, is a spin trapping agent.
Topics: Allosteric Regulation; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Hydrogen Peroxide; Hydroxyl Radical; Iron; Isatin; Kinetics; Molecular Structure; Nitrogen Oxides; Receptors, Purinergic P2; Spin Labels; Spin Trapping; Superoxides; Xanthine; Xanthine Oxidase | 1998 |
Free radical-scavenging properties of lignin.
Topics: Animals; Dietary Fiber; Enzyme Inhibitors; Free Radical Scavengers; Free Radicals; Glucosephosphate Dehydrogenase; HeLa Cells; Humans; Hydrogen-Ion Concentration; Hydroxyl Radical; Lignin; Lipid Peroxidation; Methylphenazonium Methosulfate; NAD; Nitroblue Tetrazolium; Rats; Rats, Wistar; Superoxides; Uric Acid; Xanthine Oxidase | 1998 |
Hydroxyl radical as a potential intracellular mediator of polymorphonuclear neutrophil apoptosis.
Topics: Apoptosis; Catalase; DNA Fragmentation; Flow Cytometry; Glucose Oxidase; Glutathione; Humans; Hydrogen Peroxide; Hydroxyl Radical; Iron; Iron Chelating Agents; Neutrophils; Oxidation-Reduction; Superoxide Dismutase; Superoxides; Xanthine Oxidase | 1998 |
In vitro antioxidant properties of calcium dobesilate.
Topics: Animals; Antioxidants; Aorta; Calcium; Calcium Dobesilate; Cattle; Cells, Cultured; Endothelium, Vascular; Erythrocyte Membrane; Free Radical Scavengers; Hemostatics; Humans; Hydroxyl Radical; Lipid Peroxidation; Luminescent Measurements; Neutrophils; Platelet Activating Factor; Potassium; Superoxides; Xanthine; Xanthine Oxidase | 1998 |
Antiinflammatory and antioxidant activity of plants used in traditional medicine in Ecuador.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Ecuador; Edema; Ethanol; Female; Free Radical Scavengers; Hydroxyl Radical; In Vitro Techniques; Lipid Peroxidation; Male; Medicine, Traditional; Mice; Microsomes; Microsomes, Liver; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar; Superoxides; Xanthine Oxidase | 1998 |
Phytic acid inhibits free radical formation in vitro but does not affect liver oxidant or antioxidant status in growing rats.
Topics: Animals; Antioxidants; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Glutathione; Hydroxyl Radical; Iron; Liver; Male; Oxidants; Oxidation-Reduction; Phytic Acid; Rats; Spin Labels; Superoxides; Thiobarbituric Acid Reactive Substances; Vitamin E; Xanthine; Xanthine Oxidase | 1998 |
Effects of hydroxyl radicals on KATP channels in guinea-pig ventricular myocytes.
Topics: Adenosine Triphosphate; Animals; Ferric Compounds; Glyburide; Guinea Pigs; Heart; Heart Ventricles; Hydrogen Peroxide; Hydroxyl Radical; Hypoxanthine; Patch-Clamp Techniques; Potassium Channels; Superoxides; Ventricular Function; Xanthine Oxidase | 1998 |
The iron chelator pyridoxal isonicotinoyl hydrazone (PIH) protects plasmid pUC-18 DNA against *OH-mediated strand breaks.
Topics: Antioxidants; DNA Damage; Ferrous Compounds; Hydroxyl Radical; Hypoxanthine; Iron Chelating Agents; Isoniazid; Oxidation-Reduction; Plasmids; Pyridoxal; Xanthine Oxidase | 1998 |
Reactive oxygen species activate focal adhesion kinase, paxillin and p130cas tyrosine phosphorylation in endothelial cells.
Topics: Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Crk-Associated Substrate Protein; Cytochalasin D; Cytoskeletal Proteins; Cytoskeleton; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Hydroxyl Radical; Hypoxanthine; Immunohistochemistry; Iron Chelating Agents; Microscopy, Fluorescence; Neutrophils; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proteins; Reactive Oxygen Species; Retinoblastoma-Like Protein p130; Xanthine Oxidase | 1998 |
Spin trapping and electron paramagnetic resonance spectroscopy.
Topics: Animals; Electron Spin Resonance Spectroscopy; Female; Free Radicals; Hydroxyl Radical; In Vitro Techniques; Male; Microsomes, Liver; Nitric Oxide; Rats; Rats, Sprague-Dawley; Spin Labels; Xanthine Oxidase | 1998 |
Inhibition of oxidant-induced lipid peroxidation in cultured renal tubular epithelial cells (LLC-PK1) by quercetin.
Topics: Animals; Cell Survival; Epithelial Cells; Flavonoids; Hydrogen Peroxide; Hydroxyl Radical; Hypoxanthine; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Lipid Peroxidation; LLC-PK1 Cells; Malondialdehyde; Molecular Structure; Oxidants; Quercetin; Structure-Activity Relationship; Superoxides; Swine; Xanthine Oxidase | 1998 |
Manganese scavenges superoxide and hydroxyl radicals: an in vitro study in rats.
Topics: Animals; Brain; Brain Chemistry; Chlorides; Hydroxyl Radical; In Vitro Techniques; Male; Manganese Compounds; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides; Xanthine; Xanthine Oxidase | 1999 |
Acceleration of adhesion of cancer cells and neutrophils to endothelial cells in the absence of de novo protein synthesis: possible implication for involvement of hydroxyl radicals.
Topics: Catalase; Cell Adhesion; Cell Membrane; Chelating Agents; Colonic Neoplasms; Cycloheximide; Dactinomycin; Edetic Acid; Endothelium, Vascular; Humans; Hydrogen Peroxide; Hydroxyl Radical; Hypoxanthine; Neutrophils; Nitrates; Protein Biosynthesis; Reactive Oxygen Species; Superoxide Dismutase; Tumor Cells, Cultured; Xanthine Oxidase | 1999 |
Presence of bleomycin-detectable free iron in the alveolar system of preterm infants.
Topics: Albumins; Bleomycin; Bronchoalveolar Lavage Fluid; Electron Spin Resonance Spectroscopy; Ferritins; Humans; Hydrogen Peroxide; Hydroxyl Radical; Infant, Newborn; Infant, Premature; Iron; Lactoferrin; Oxidation-Reduction; Pulmonary Alveoli; Reactive Oxygen Species; Respiratory Distress Syndrome, Newborn; Transferrin; Xanthine; Xanthine Oxidase | 1999 |
Cytosolic Ca2+ movements of endothelial cells exposed to reactive oxygen intermediates: role of hydroxyl radical-mediated redox alteration of cell-membrane Ca2+ channels.
Topics: Animals; Aorta; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Cell Respiration; Cells, Cultured; Cyclic N-Oxides; Cytosol; Dithiothreitol; Endothelium, Vascular; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Iron Chelating Agents; Nickel; Oxidants; Oxidation-Reduction; Phenanthrolines; Reactive Oxygen Species; Swine; Xanthine; Xanthine Oxidase | 1999 |
In vitro photogenotoxic activity of clinafloxacin: a paradigm predicting photocarcinogenicity.
Topics: Allopurinol; Animals; Anti-Infective Agents; Carcinogenicity Tests; CHO Cells; Cricetinae; DNA; Fluoroquinolones; Free Radical Scavengers; Hydroxyl Radical; Keratinocytes; Male; Mice; Mice, Inbred Strains; Mutagenicity Tests; Ultraviolet Rays | 1999 |
SOS-dependent A-->G transitions induced by hydroxyl radical generating system hypoxanthine/xanthine oxidase/Fe3+/EDTA are accompanied by the increase of Fapy-adenine content in M13 mp18 phage DNA.
Topics: Bacteriophage M13; Base Sequence; DNA Damage; DNA, Single-Stranded; DNA, Viral; Edetic Acid; Ferric Compounds; Genes, Viral; Hydroxyl Radical; Hypoxanthine; Molecular Sequence Data; Mutagenesis; Mutation; Oxidative Stress; Point Mutation; Pyrimidines; SOS Response, Genetics; Xanthine Oxidase | 1999 |
Formation of the aldehydic choline glycerophospholipids in human red blood cell membrane peroxidized with an azo initiator.
Topics: Aldehydes; Amidines; Chromatography, High Pressure Liquid; Erythrocyte Membrane; Fatty Acids, Unsaturated; Free Radicals; Glycerophospholipids; Glycerylphosphorylcholine; Humans; Hydroxyl Radical; Iron; Lipid Peroxidation; Lipid Peroxides; Oxadiazoles; Oxidants; Oxidation-Reduction; Sulfonamides; Thiobarbituric Acid Reactive Substances; Xanthine; Xanthine Oxidase | 1999 |
Reactivity of an indolinonic aminoxyl with superoxide anion and hydroxyl radicals.
Topics: Cyclic N-Oxides; Deoxyribose; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Hydroxyl Radical; Hypoxanthine; Molecular Structure; Spectrophotometry; Superoxides; Thiobarbituric Acid Reactive Substances; Xanthine Oxidase | 1999 |
Antioxidant properties of aminoguanidine.
Topics: Antioxidants; Cyclic N-Oxides; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Fluorescence; Guanidines; Hydroxyl Radical; Phycocyanin; Spin Labels; Spin Trapping; Xanthine Oxidase | 1999 |
Generation of reactive oxygen species by the faecal matrix.
Topics: Ascorbic Acid; Bacteria; Catechols; Chromatography, High Pressure Liquid; Edetic Acid; Feces; Free Radical Scavengers; Gentisates; Humans; Hydroxybenzoates; Hydroxyl Radical; Hypoxanthine; Phytic Acid; Reactive Oxygen Species; Salicylic Acid; Xanthine Oxidase | 2000 |
Fapyadenine is a moderately efficient chain terminator for prokaryotic DNA polymerases.
Topics: Animals; Bacterial Proteins; Bacteriophage M13; Cattle; DNA Damage; DNA Polymerase beta; DNA Polymerase I; DNA Replication; DNA-Directed DNA Polymerase; DNA-Formamidopyrimidine Glycosylase; DNA, Single-Stranded; DNA, Viral; Edetic Acid; Escherichia coli Proteins; Hydroxyl Radical; Hypoxanthine; Iron; N-Glycosyl Hydrolases; Oxidation-Reduction; Oxidative Stress; Poly A; Pyrimidines; Templates, Genetic; Xanthine Oxidase | 2000 |
On the role of hydroxyl radical and the effect of tetrandrine on nuclear factor--kappaB activation by phorbol 12-myristate 13-acetate.
Topics: Alkaloids; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Benzylisoquinolines; Carcinogens; DNA-Binding Proteins; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hydroxyl Radical; Jurkat Cells; NF-kappa B; Oxidants; Phosphorylation; Superoxides; Tetradecanoylphorbol Acetate; Xanthine; Xanthine Oxidase | 2000 |
Influence of melatonin on free radical-induced changes in rat pancreatic beta-cells in vitro.
Topics: Alloxan; Animals; Electron Spin Resonance Spectroscopy; Female; Free Radical Scavengers; Free Radicals; Hydroxyl Radical; Hypoxanthine; In Situ Nick-End Labeling; Insulin; Insulin Secretion; Islets of Langerhans; Lipid Peroxidation; Male; Melatonin; Necrosis; Rats; Rats, Wistar; Reactive Oxygen Species; Xanthine Oxidase | 2000 |
Detection of superoxide anion using an isotopically labeled nitrone spin trap: potential biological applications.
Topics: Calmodulin; Citrulline; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Half-Life; Hydroxyl Radical; Kinetics; NADP; Nitric Oxide Synthase; Nitrogen Isotopes; Nitrogen Oxides; Reperfusion Injury; Sensitivity and Specificity; Spin Labels; Spin Trapping; Superoxides; Xanthine; Xanthine Oxidase | 2000 |
A one-step synthesis of 2-(2-Pyridyl)-3H-indol-3-one N-oxide: is it an efficient spin trap for hydroxyl radical?
Topics: Electron Spin Resonance Spectroscopy; Hydroxyl Radical; Indicators and Reagents; Indoles; Molecular Structure; Pyridines; Spin Labels; Xanthine; Xanthine Oxidase | 2000 |
Reperfusion injury pathophysiology in sickle transgenic mice.
Topics: Allopurinol; Anemia, Sickle Cell; Animals; Biomarkers; Enzyme Inhibitors; Ethane; Hemoglobin, Sickle; Humans; Hydroxybenzoates; Hydroxyl Radical; Kidney; Lipid Peroxidation; Liver; Mice; Mice, Inbred C57BL; Mice, Transgenic; NF-kappa B; Reference Values; Reperfusion Injury; Salicylic Acid; Xanthine Dehydrogenase; Xanthine Oxidase | 2000 |
Actions of reactive oxygen species on AH/type 2 myenteric neurons in guinea pig distal colon.
Topics: Action Potentials; Animals; Caffeine; Colon; Guinea Pigs; Hydrogen Peroxide; Hydroxyl Radical; Hypoxanthine; Male; Myenteric Plexus; Neurons; Oxidants; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Reactive Oxygen Species; Xanthine Oxidase | 2000 |
Does xanthine oxidase contribute to the hydroxyl radical generation in ischemia and reperfusion of the cochlea?
Topics: Action Potentials; Allopurinol; Animals; Cochlea; Enzyme Inhibitors; Free Radical Scavengers; Guinea Pigs; Hydroxyl Radical; Ischemia; Oxypurinol; Reperfusion Injury; Thiourea; Xanthine Oxidase | 2001 |
Oxygen radical-induced mitochondrial DNA damage and repair in pulmonary vascular endothelial cell phenotypes.
Topics: Animals; Cell Death; Cells, Cultured; DNA Damage; DNA Mutational Analysis; DNA Repair; DNA, Mitochondrial; Dose-Response Relationship, Drug; Endothelium, Vascular; Hydroxyl Radical; Microcirculation; Phenotype; Polymerase Chain Reaction; Pulmonary Artery; Pulmonary Veins; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxides; Vitamin K; Xanthine Oxidase | 2001 |
Electron paramagnetic resonance study on free radical scavenging and/or generating activity of dopamine-4-O-sulfate.
Topics: Dopamine; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Horseradish Peroxidase; Hydroxyl Radical; Periodic Acid; Spectrophotometry, Ultraviolet; Superoxides; Ultraviolet Rays; Xanthine Oxidase | 2001 |
Nitric oxide enhances MPP(+)-induced hydroxyl radical generation via depolarization activated nitric oxide synthase in rat striatum.
Topics: 1-Methyl-4-phenylpyridinium; Allopurinol; Animals; Dopamine; Enzyme Inhibitors; Extracellular Space; Herbicides; Hydroxybenzoates; Hydroxyl Radical; Iron; Iron Chelating Agents; Male; Membrane Potentials; Microdialysis; Neostriatum; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Parkinson Disease; Potassium; Rats; Rats, Wistar | 2001 |
Allopurinol suppresses para-nonylphenol and 1-methyl-4-phenylpyridinium ion (MPP(+))-induced hydroxyl radical generation in rat striatum.
Topics: 1-Methyl-4-phenylpyridinium; Allopurinol; Animals; Dose-Response Relationship, Drug; Drug Interactions; Free Radical Scavengers; Hazardous Substances; Hydroxyl Radical; Male; Microdialysis; Neostriatum; Nerve Degeneration; Parkinson Disease; Parkinson Disease, Secondary; Phenols; Rats; Rats, Wistar | 2001 |
Nitric oxide induces hydroxyl radical generation in rat hearts via depolarization-induced nitric oxide synthase activation.
Topics: Allopurinol; Animals; Dose-Response Relationship, Drug; Enzyme Activation; Female; Heart; Hydroxyl Radical; Male; Microdialysis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Potassium; Potassium Chloride; Rats; Rats, Wistar; Tyramine | 2001 |
Modulation of platelet aggregation by areca nut and betel leaf ingredients: roles of reactive oxygen species and cyclooxygenase.
Topics: Animals; Arachidonic Acid; Areca; Blood Platelets; Collagen; Free Radical Scavengers; Hydroxyl Radical; Oxidation-Reduction; Plant Extracts; Plant Leaves; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Rabbits; Reactive Oxygen Species; Superoxides; Thromboxane B2; Xanthine Oxidase | 2002 |
Electron paramagnetic resonance spin trapping investigation into the kinetics of glutathione oxidation by the superoxide radical: re-evaluation of the rate constant.
Topics: Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Glutathione; Hydroxyl Radical; Hypoxanthine; In Vitro Techniques; Kinetics; Oxidation-Reduction; Spin Trapping; Superoxides; Xanthine Oxidase | 2002 |
Mechanisms for the induction of oxidative stress in Syrian hamster embryo cells by acrylonitrile.
Topics: Acrylonitrile; Animals; Carcinogens; Catalase; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Dose-Response Relationship, Drug; Drug Synergism; Embryo, Mammalian; Glutathione; Hydroxybenzoates; Hydroxyl Radical; Mesocricetus; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase; Time Factors; Triazoles; Xanthine Oxidase | 2002 |
Nitrate tolerance does not increase production of peroxynitrite in the heart.
Topics: Animals; Aorta, Thoracic; Biomarkers; Drug Tolerance; Heart; Heart Ventricles; Hydroxyl Radical; In Vitro Techniques; Male; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin; Peroxynitrous Acid; Rats; Rats, Wistar; Reactive Oxygen Species; Time; Xanthine Dehydrogenase; Xanthine Oxidase | 2002 |
An in vitro hydroxyl radical generation assay for microdialysis sampling calibration.
Topics: Ascorbic Acid; Calibration; Chromatography, High Pressure Liquid; Hydroxybenzoates; Hydroxyl Radical; Hypoxanthine; Microdialysis; Uric Acid; Xanthine; Xanthine Oxidase | 2002 |
Xanthine oxidase and xanthine dehydrogenase inhibition by the procyanidin-rich French maritime pine bark extract, pycnogenol: a protein binding effect.
Topics: Antioxidants; Ascorbate Oxidase; Biflavonoids; Catechin; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Flavonoids; Free Radical Scavengers; Glucose Oxidase; Hydroxyl Radical; Oxidation-Reduction; Plant Extracts; Proanthocyanidins; Protein Binding; Superoxides; Xanthine Dehydrogenase; Xanthine Oxidase | 2002 |
Production of hydroxyl free radical in the xanthine oxidase system with addition of 1-methyl-3-nitro-1-nitrosoguanidine.
Topics: Cell-Free System; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Humans; Hydrogen Peroxide; Hydroxyl Radical; Methylnitronitrosoguanidine; Spin Labels; Stomach Neoplasms; Xanthine Oxidase | 2002 |
In vitro studies on the activity of japanese kampo herbal medicines Oren-Gedoku-To (TJ-15) and Toki-Shakuyaku-San (TJ-23) as scavengers of free radicals.
Topics: Animals; Ascorbic Acid; Biphenyl Compounds; Drugs, Chinese Herbal; Electron Transport; Free Radical Scavengers; Hydroxyl Radical; In Vitro Techniques; Iron; Lipid Peroxidation; Male; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Oxidants; Oxidative Stress; Picrates; Rats; Rats, Wistar; Superoxides; Xanthine Oxidase | 1994 |
Scavenging property of three cresol isomers against H2O2, hypochlorite, superoxide and hydroxyl radicals.
Topics: Acridines; Cresols; DNA Damage; Drug Interactions; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Hypochlorous Acid; Isomerism; Luminescent Measurements; Superoxides; Xanthine; Xanthine Oxidase | 2002 |
Neutrophil-derived hydroxyl radicals mediate interleukin-8-induced increases in tetragastrin-stimulated acid secretion in rats.
Topics: Allopurinol; Animals; Dimethyl Sulfoxide; Gastric Acid; Hydroxyl Radical; Interleukin-8; Male; Neutrophils; Oxidants; Rats; Rats, Wistar; Superoxide Dismutase; Tetragastrin | 2003 |
Allopurinol improves cardiac dysfunction after ischemia-reperfusion via reduction of oxidative stress in isolated perfused rat hearts.
Topics: Adenine Nucleotides; Allopurinol; Animals; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Heart; Hydroxyl Radical; In Vitro Techniques; L-Lactate Dehydrogenase; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Oxidative Stress; Perfusion; Pressure; Purines; Rats; Spin Labels; Thiobarbituric Acid Reactive Substances; Ventricular Function, Left; Xanthine Oxidase | 2003 |
Antioxidative properties of Iberis amara extracts in biochemical model reactions.
Topics: Adolescent; Adult; alpha-Linolenic Acid; Antioxidants; Brassicaceae; Chromatography, Gas; Ethylenes; Female; Humans; Hydroxyl Radical; In Vitro Techniques; Indicators and Reagents; Light; Lipid Peroxidation; Lipoproteins, LDL; Male; Models, Biological; Oxidation-Reduction; Peroxidase; Peroxynitrous Acid; Plant Extracts; Plants, Medicinal; Rose Bengal; Xanthine Oxidase | 2003 |
Antioxidant and free radical scavenging activity of isoflavone metabolites.
Topics: Animals; Antioxidants; Blotting, Western; Cell Line; Cell Survival; Electron Spin Resonance Spectroscopy; Ferric Compounds; Free Radical Scavengers; Glycine max; Hydroxyl Radical; Isoflavones; Macrophages; Mice; Nitric Oxide; Oxidants; Oxidation-Reduction; Superoxides; Xanthine Oxidase | 2003 |
Selective in vitro antioxidant properties of bisphosphonates.
Topics: Animals; Antioxidants; Biphenyl Compounds; Diphosphates; Diphosphonates; Fatty Acids; Ferrous Compounds; Free Radical Scavengers; Free Radicals; Hydroxyl Radical; Lipid Peroxidation; Microsomes, Liver; Picrates; Rats; Xanthine Oxidase | 2004 |
Antioxidant activity in vitro of two aromatic compounds from Caesalpinia sappan L.
Topics: Antioxidants; Benzofurans; Benzopyrans; Caesalpinia; Chromatography, Thin Layer; Enzyme Inhibitors; Free Radical Scavengers; Hydroxyl Radical; Plant Bark; Superoxides; Xanthine Oxidase | 2003 |
Non-invasive analysis of reactive oxygen species generated in rats with water immersion restraint-induced gastric lesions using in vivo electron spin resonance spectroscopy.
Topics: Allopurinol; Animals; Antioxidants; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Gastric Mucosa; Hydroxyl Radical; Immersion; Magnetic Resonance Imaging; Male; Models, Animal; Neutrophil Infiltration; Peroxidase; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Stomach Ulcer; Stress, Physiological | 2004 |
Effects of reactive oxygen and nitrogen species on cyclooxygenase-1 and -2 activities.
Topics: Animals; Catalase; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Hydrogen Peroxide; Hydroxyl Radical; Male; Nitric Oxide; Peroxynitrous Acid; Placenta; Pregnancy; Prostaglandin-Endoperoxide Synthases; Reactive Nitrogen Species; Reactive Oxygen Species; Seminal Vesicles; Sheep; Superoxides; Triazenes; Xanthine; Xanthine Oxidase | 2004 |
Evaluation and standardisation of the antioxidant properties of two Indian remedies with biochemical test assays.
Topics: Antioxidants; Cell Survival; Extracellular Space; Granulocytes; Humans; Hyaluronic Acid; Hydrogen Peroxide; Hydroxyl Radical; Hydroxylamine; Hypoxanthine; In Vitro Techniques; India; Leukocytes; Medicine, Ayurvedic; Oxidants; Peroxidase; Phenols; Reactive Oxygen Species; Superoxides; Uric Acid; Xanthine Oxidase | 2005 |
Effects of edaravone on human neutrophil function.
Topics: Antipyrine; Calcium; Chemotaxis; Dose-Response Relationship, Drug; Edaravone; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hydroxyl Radical; In Vitro Techniques; Neutrophils; Phagocytosis; Reactive Oxygen Species; Reference Values; Xanthine; Xanthine Oxidase | 2005 |
Effects of garcinol on free radical generation and NO production in embryonic rat cortical neurons and astrocytes.
Topics: Animals; Astrocytes; Brain; Cell Survival; Cells, Cultured; DNA; Enzyme Inhibitors; Free Radicals; Hydrogen Peroxide; Hydroxyl Radical; Iron; Lipopolysaccharides; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Terpenes; Xanthine Oxidase | 2005 |
Assessment of the antioxidant activities of Brazilian extracts of propolis alone and in topical pharmaceutical formulations.
Topics: Antioxidants; Area Under Curve; Chemistry, Pharmaceutical; Culture Media; Deoxyribose; Dose-Response Relationship, Drug; Drug Industry; Ethanol; Flavonoids; Free Radical Scavengers; Glycols; Hydrogen Peroxide; Hydroxyl Radical; Inhibitory Concentration 50; Iron; Lipid Peroxidation; Luminol; Phenols; Polyphenols; Propolis; Xanthine; Xanthine Oxidase | 2005 |
Ca2+ is mobilized by hydroxyl radical but not by superoxide in RTH-149 cells: the oxidative switching-on of Ca2+ signaling.
Topics: Animals; Calcium Signaling; Carcinoma, Hepatocellular; Cell Line, Tumor; Estrenes; Fluorescent Dyes; Hydroxyl Radical; Hypoxanthine; Oxidants; Oxidation-Reduction; Pyrrolidinones; Rhodamines; Superoxides; Trout; Verapamil; Xanthine Oxidase | 2005 |
Superoxide-dependent oxidation of melatonin by myeloperoxidase.
Topics: Animals; Antioxidants; Catalase; Catalysis; Cattle; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dimerization; Dose-Response Relationship, Drug; Free Radicals; Heme; Humans; Hydrogen Peroxide; Hydroxyl Radical; Hypochlorous Acid; Kynuramine; Liver; Mass Spectrometry; Melatonin; Models, Chemical; Neutrophils; Oxygen; Ozone; Peroxidase; Protein Binding; Superoxides; Taurine; Time Factors; Xanthine Oxidase | 2005 |
Reconstitution and characterization of aminopyrrolnitrin oxygenase, a Rieske N-oxygenase that catalyzes unusual arylamine oxidation.
Topics: Amines; Binding Sites; Cloning, Molecular; Escherichia coli; Free Radical Scavengers; Heterocyclic Compounds; Hydroxyl Radical; Iron; Oxygen; Oxygenases; Pseudomonas fluorescens; Pyrrolnitrin; Substrate Specificity; Superoxide Dismutase; Xanthine Oxidase | 2005 |
Allopurinol suppresses 2-bromoethylamine and 1-methyl-4-phenylpyridinium ion (MPP(+))-induced hydroxyl radical generation in rat striatum.
Topics: 1-Methyl-4-phenylpyridinium; Allopurinol; Amine Oxidase (Copper-Containing); Animals; Corpus Striatum; Drug Synergism; Enzyme Inhibitors; Ethylamines; Hydroxyl Radical; Male; Microdialysis; Oxidative Stress; Rats; Rats, Wistar | 2006 |
Vanadium promotes hydroxyl radical formation by activated human neutrophils.
Topics: Adenosine Triphosphate; Adult; Carcinogens; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Humans; Hydrogen Peroxide; Hydroxyl Radical; Iodine; Luminescence; Neutrophil Activation; Neutrophils; Oxidants; Peroxidase; Phorbol Esters; Spin Labels; Superoxides; Trace Elements; Vanadium; Xanthine; Xanthine Oxidase | 2006 |
Structure prerequisite for antioxidant activity of silybin in different biochemical systems in vitro.
Topics: Antioxidants; Cholesterol, LDL; Cytosol; Free Radical Scavengers; Humans; Hydroxyl Radical; Molecular Structure; Neutrophils; Oxidation-Reduction; Protein Kinase C; Silybin; Silymarin; Superoxides; Thiobarbituric Acid Reactive Substances; Xanthine Oxidase | 2006 |
Antioxidative flavanone glycosides from the branches and leaves of Viscum coloratum.
Topics: Antioxidants; Carbohydrate Conformation; Carbohydrate Sequence; Flavanones; Free Radical Scavengers; Glucosides; Hydroxyl Radical; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Oxidants; Plant Extracts; Plant Leaves; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Superoxides; Viscum; Xanthine Oxidase | 2006 |
Biphasic regulation of angiogenesis by reactive oxygen species.
Topics: Catalase; Cell Adhesion; Cell Movement; Cell Proliferation; Endothelial Cells; Humans; Hydrogen Peroxide; Hydroxyl Radical; Indicators and Reagents; Neovascularization, Physiologic; Reactive Oxygen Species; Superoxide Dismutase; Umbilical Veins; Xanthine Oxidase | 2006 |
Sesame oil attenuates acute iron-induced lipid peroxidation-associated hepatic damage in mice.
Topics: Animals; Hydroxyl Radical; Iron; Lipid Peroxidation; Liver; Liver Diseases; Male; Mice; Mice, Inbred BALB C; Oxidative Stress; Sesame Oil; Superoxides; Xanthine Oxidase | 2006 |
Influence of heating on the activity of xanthine oxidase in tumor cells subjected to the phototoxic action of hematoporphyrin derivative.
Topics: Animals; Carcinoma, Ehrlich Tumor; Female; Hematoporphyrin Derivative; Hematoporphyrin Photoradiation; Hydrogen Peroxide; Hydroxyl Radical; Hyperthermia, Induced; Mice; Oxidation-Reduction; Photosensitizing Agents; Superoxides; Tumor Cells, Cultured; Xanthine Oxidase | 2007 |
Phenolic compounds, organic acids profiles and antioxidative properties of beefsteak fungus (Fistulina hepatica).
Topics: Acids; Antioxidants; Basidiomycota; Chromatography, High Pressure Liquid; Free Radical Scavengers; Hydroxyl Radical; Hypochlorous Acid; Indicators and Reagents; Nitroblue Tetrazolium; Phenols; Spectrophotometry, Ultraviolet; Xanthine Oxidase | 2007 |
The effect of sesamol on systemic oxidative stress and hepatic dysfunction in acutely iron-intoxicated mice.
Topics: Acute Disease; Animals; Antioxidants; Aspartate Aminotransferases; Benzodioxoles; Hydroxyl Radical; Iron; Lipid Peroxidation; Liver; Male; Mice; Mice, Inbred BALB C; Oxidative Stress; Phenols; Superoxides; Xanthine Oxidase | 2007 |
Antioxidant activities and free radical scavenging potential of Bauhinia microstachya (RADDI) MACBR. (Caesalpinaceae) extracts linked to their polyphenol content.
Topics: Antioxidants; Bauhinia; Chromans; Chromatography, High Pressure Liquid; Ethanol; Flavonoids; Free Radical Scavengers; Hydroxyl Radical; Luminescence; Nitric Oxide; Phenols; Plant Extracts; Plant Leaves; Polyphenols; Solvents; Spectrophotometry, Ultraviolet; Superoxides; Thiobarbituric Acid Reactive Substances; Water; Xanthine Oxidase | 2007 |
The activity of an extract and fraction of Agrimonia eupatoria L. against reactive species.
Topics: Agrimonia; Flavonoids; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Hypochlorous Acid; Peroxynitrous Acid; Plant Extracts; Reactive Oxygen Species; Superoxides; Xanthine Oxidase | 2007 |
Clindamycin phosphate scavenges hydroxyl radical.
Topics: Anti-Bacterial Agents; Clindamycin; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Hydroxyl Radical; Oxidation-Reduction; Spin Trapping; Superoxides; Xanthine Oxidase | 2007 |
Ciclopirox olamine directly scavenges hydroxyl radical.
Topics: Antifungal Agents; Ciclopirox; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Humans; Hydroxyl Radical; Pyridones; Superoxides; Ultrasonography; Xanthine Oxidase | 2008 |
The prophylactic protective effect of sesamol against ferric-nitrilotriacetate-induced acute renal injury in mice.
Topics: Animals; Antioxidants; Benzodioxoles; Blood Urea Nitrogen; Chelating Agents; Creatinine; Dose-Response Relationship, Drug; Ferric Compounds; Hydroxyl Radical; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Mice; Mice, Inbred BALB C; Nitrilotriacetic Acid; Oxidants; Phenols; Protective Agents; Proteins; Superoxides; Xanthine Oxidase | 2008 |
Existence of a new reactive intermediate oxygen species in hypoxanthine and xanthine oxidase reaction.
Topics: Hydroxyl Radical; Hypoxanthine; Luminol; Reactive Oxygen Species; Xanthine Oxidase | 2008 |
Reactive oxygen species generators affect quality parameters and apoptosis markers differently in red deer spermatozoa.
Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Caspases; Catalase; Cell Survival; Deer; Enzyme Activation; Flow Cytometry; Hydrogen Peroxide; Hydroxyl Radical; Iron; Male; Membrane Potential, Mitochondrial; Microscopy, Fluorescence; Oxidative Stress; Reactive Oxygen Species; Sperm Motility; Spermatozoa; Superoxides; Time Factors; Xanthine Oxidase | 2009 |
Radical scavenging activity of bisbenzylisoquinoline alkaloids and traditional prophylactics against chemotherapy-induced oral mucositis.
Topics: Allopurinol; Antimetabolites, Antineoplastic; Antineoplastic Agents; Benzothiazoles; Benzylisoquinolines; Biphenyl Compounds; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Hydroxyl Radical; Mucositis; Oxidants; Picrates; Reactive Oxygen Species; Structure-Activity Relationship; Sulfonic Acids | 2009 |
Cellular and molecular mechanisms of 17beta-estradiol postconditioning protection against gastric mucosal injury induced by ischemia/reperfusion in rats.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Cell Proliferation; Estradiol; Estrogen Antagonists; Fulvestrant; Gastric Mucosa; Hydroxyl Radical; Male; Malondialdehyde; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase; Xanthine Oxidase | 2010 |
Antioxidant properties, radical scavenging activity and biomolecule protection capacity of flavonoid naringenin and its glycoside naringin: a comparative study.
Topics: Animals; Antioxidants; Cattle; Chelating Agents; DNA Fragmentation; Dose-Response Relationship, Drug; Flavanones; Free Radical Scavengers; Glutathione; Glycosides; Glycosylation; Hydroxyl Radical; Lipid Peroxidation; Male; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Superoxides; Xanthine Oxidase | 2010 |
Two-dimensional imaging of spontaneous ultra-weak photon emission from the human skin: role of reactive oxygen species.
Topics: Adult; Diagnostic Imaging; Electron Spin Resonance Spectroscopy; Hand; Head; Humans; Hydrogen Peroxide; Hydroxyl Radical; Iron; Male; Oxidative Stress; Photometry; Photons; Reactive Oxygen Species; Skin; Skin Physiological Phenomena; Superoxides; Torso; Xanthine; Xanthine Oxidase | 2011 |
HPLC-DAD-MS/MS profiling of antioxidant flavonoid glycosides in sea buckthorn (Hippophae rhamnoides L.) seeds.
Topics: Antioxidants; Chromatography, High Pressure Liquid; Flavonoids; Glycosides; Hippophae; Hydroxyl Radical; Iron Chelating Agents; Molecular Structure; Seeds; Tandem Mass Spectrometry; Xanthine Oxidase | 2012 |
Effect of polymerization on antioxidant and xanthine oxidase inhibitory potential of sea buckthorn (H. rhamnoides) proanthocyanidins.
Topics: Antioxidants; Benzothiazoles; Catechin; Chelating Agents; Free Radical Scavengers; Hippophae; Hydroxyl Radical; Iron; Polymerization; Proanthocyanidins; Seeds; Sulfonic Acids; Superoxides; Xanthine Oxidase | 2012 |
In vitro evaluation of selected benzimidazole derivatives as an antioxidant and xanthine oxidase inhibitors.
Topics: Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds; Catechol Oxidase; Cattle; Enzyme Inhibitors; Hydroxyl Radical; Milk; Picrates; Protein Binding; Xanthine Oxidase | 2013 |
[Biochemical mechanisms of the cardioprotective effect of the K(ATP) channels opener flocalin (medicinal form) in ischemia-reperfusion of myocardium].
Topics: Animals; Apoptosis; Arginase; Cardiotonic Agents; Dogs; Heart; Heme Oxygenase (Decyclizing); Hydroxyl Radical; Lipoxygenase; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Peroxynitrous Acid; Pinacidil; Tablets; Xanthine Oxidase | 2013 |
Synthesis, xanthine oxidase inhibition, and antioxidant screening of benzophenone tagged thiazolidinone analogs.
Topics: Antioxidants; Benzophenones; Biphenyl Compounds; Humans; Hydrogen Bonding; Hydroxyl Radical; Lipid Peroxidation; Milk, Human; Molecular Docking Simulation; Molecular Structure; Picrates; Thiazolidines; Xanthine Oxidase | 2014 |
[Induction of oxidative stress in heart mitochondria in brain focal ischemia-reperfusion and protective effect of ecdysterone].
Topics: Animals; Brain Ischemia; Cardiotonic Agents; Ecdysterone; Heart; Hydrogen Peroxide; Hydroxyl Radical; Invertebrate Hormones; Lipid Peroxidation; Lipoxygenase; Malondialdehyde; Mitochondria, Heart; Oxidative Stress; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Reperfusion Injury; Superoxides; Survival Analysis; Xanthine Oxidase | 2014 |
Sensitive electrochemical measurement of hydroxyl radical generation induced by the xanthine-xanthine oxidase system.
Topics: Catalysis; Electrochemical Techniques; Electron Spin Resonance Spectroscopy; Ferric Compounds; Glucose; Glucose Dehydrogenases; Humans; Hydroquinones; Hydroxyl Radical; Oxidation-Reduction; Xanthine; Xanthine Oxidase; Xylenes | 2014 |
Phosphate-Linked Silibinin Dimers (PLSd): New Promising Modified Metabolites.
Topics: Antioxidants; Cell Survival; Dimerization; Free Radical Scavengers; Hep G2 Cells; Humans; Hydroxyl Radical; Oxidation-Reduction; Oxidative Stress; Phosphates; Polyphenols; Reactive Oxygen Species; Silybin; Silymarin; Solubility; Xanthine; Xanthine Oxidase | 2017 |