Page last updated: 2024-09-04

hydroxyl radical and 8-hydroxyguanine

hydroxyl radical has been researched along with 8-hydroxyguanine in 20 studies

Compound Research Comparison

Studies
(hydroxyl radical)
Trials
(hydroxyl radical)
Recent Studies (post-2010)
(hydroxyl radical)
Studies
(8-hydroxyguanine)
Trials
(8-hydroxyguanine)
Recent Studies (post-2010) (8-hydroxyguanine)
10,147263,6571,28914481

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.00)18.7374
1990's3 (15.00)18.2507
2000's9 (45.00)29.6817
2010's7 (35.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Eneff, KL; Floyd, RA; Hogsett, WE; Tingey, DT; West, MS1
Ballmaier, D; Epe, B1
Floyd, RA; Maidt, ML; Phillips, JR; Price, S; Pye, Q; Schneider, JE1
Alam, ZI; Cairns, N; Daniel, SE; Halliwell, B; Jenner, A; Jenner, P; Lees, AJ; Marsden, CD1
Bretonniere, Y; Cadet, J; Douki, T1
Hazen, SL; Shen, Z; Wu, W1
Malins, DC; Ostrander, GK; Polissar, NL; Vinson, MA1
Choi, JY; Chung, MH; Doetsch, PW; Kim, JE; Kim, JS; You, HJ1
Barker, EA; Johnson, PM; Malins, DC; Polissar, NL; Vinson, MA; Wheeler, TM1
Cadet, J; Douki, T; Gasparutto, D; Ravanat, JL1
Jena, NR; Mishra, PC1
Bruskov, VI; Chernikov, AV; Gudkov, SV; Shtarkman, IN1
Andrievsky, GV; Bruskov, VI; Gudkov, SV; Tykhomyrov, AA1
Cadet, J; Douki, T1
Collins, JJ; Devadoss, B; Foti, JJ; Walker, GC; Winkler, JA1
Berezhnov, AV; Bruskov, VI; Chernikov, AV; Garmash, SA; Gudkov, SV; Ivanov, VE; Karp, OE; Smirnova, VS; Usacheva, AM1
Kobayashi, J; Suzuki, M; Takao, M; Takatori, K; Yamasaki, A; Yoshikawa, Y; Zhang-Akiyama, QM1
Gordhan, BG; Hassim, F; Kana, BD; Papadopoulos, AO1
Bilotti, K; Delaney, S; Tarantino, ME1
Bhattacharjee, K; Shukla, PK1

Reviews

1 review(s) available for hydroxyl radical and 8-hydroxyguanine

ArticleYear
Oxidative damage to DNA: formation, measurement and biochemical features.
    Mutation research, 2003, Oct-29, Volume: 531, Issue:1-2

    Topics: Animals; DNA Adducts; DNA Damage; Guanine; Humans; Hydroxyl Radical; Mutagenesis; Oxidation-Reduction; Oxidative Stress; Oxygen; Radiation Dosage; Reactive Oxygen Species

2003

Other Studies

19 other study(ies) available for hydroxyl radical and 8-hydroxyguanine

ArticleYear
Hydroxyl free radical mediated formation of 8-hydroxyguanine in isolated DNA.
    Archives of biochemistry and biophysics, 1988, Volume: 262, Issue:1

    Topics: Animals; Cattle; DNA; DNA Damage; Guanine; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Thiourea; Ultraviolet Rays

1988
Oxidative DNA damage induced by potassium bromate under cell-free conditions and in mammalian cells.
    Carcinogenesis, 1995, Volume: 16, Issue:2

    Topics: Animals; Bromates; Bromine; Carcinogens; Cattle; Cell-Free System; Cells, Cultured; DNA Damage; DNA, Viral; Free Radical Scavengers; Free Radicals; Glutathione; Guanine; Hydroxyl Radical; Kidney; Leukemia L1210; Mice; Oxidation-Reduction; Reactive Oxygen Species

1995
Methylene blue and rose bengal photoinactivation of RNA bacteriophages: comparative studies of 8-oxoguanine formation in isolated RNA.
    Archives of biochemistry and biophysics, 1993, Feb-15, Volume: 301, Issue:1

    Topics: Centrifugation, Density Gradient; Guanine; Hydroxides; Hydroxyl Radical; Iron Chelating Agents; Light; Methylene Blue; Oxygen; Photochemistry; RNA Phages; RNA, Viral; Rose Bengal; Singlet Oxygen; Temperature

1993
Oxidative DNA damage in the parkinsonian brain: an apparent selective increase in 8-hydroxyguanine levels in substantia nigra.
    Journal of neurochemistry, 1997, Volume: 69, Issue:3

    Topics: Aged; Aged, 80 and over; Aging; Base Composition; DNA; DNA Damage; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Hydroxyl Radical; Middle Aged; Nitrates; Oxidants; Oxidation-Reduction; Parkinson Disease; Pyrimidines; Reference Values; Regression Analysis; Substantia Nigra

1997
Protection against radiation-induced degradation of DNA bases by polyamines.
    Radiation research, 2000, Volume: 153, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Amidines; Cytosine; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Dimethyl Sulfoxide; DNA; DNA Damage; Dose-Response Relationship, Drug; Gamma Rays; Gas Chromatography-Mass Spectrometry; Guanine; Hydroxyl Radical; Oxidation-Reduction; Polyamines; Purines; Putrescine; Pyrimidines; Radiation-Protective Agents; Solutions; Spermidine; Spermine

2000
Activated leukocytes oxidatively damage DNA, RNA, and the nucleotide pool through halide-dependent formation of hydroxyl radical.
    Biochemistry, 2000, May-09, Volume: 39, Issue:18

    Topics: Animals; Bromates; DNA Damage; Eosinophils; Guanine; Halogens; Humans; Hydroxyl Radical; Hypochlorous Acid; Leukocytes; Liver; Mutagens; Neutrophils; Nucleotides; Oxidative Stress; Peroxidases; Reactive Oxygen Species; RNA

2000
Single 8-oxo-guanine and 8-oxo-adenine lesions induce marked changes in the backbone structure of a 25-base DNA strand.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Nov-07, Volume: 97, Issue:23

    Topics: Adenine; DNA; DNA Damage; Guanine; Hydroxyl Radical; Multivariate Analysis; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Spectroscopy, Fourier Transform Infrared

2000
Ntg2 of Saccharomyces cerevisiae repairs the oxidation products of 8-hydroxyguanine.
    Biochemical and biophysical research communications, 2001, Aug-03, Volume: 285, Issue:5

    Topics: Borohydrides; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; DNA; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA-Formamidopyrimidine Glycosylase; Dose-Response Relationship, Radiation; Escherichia coli Proteins; Gamma Rays; Guanine; Hydrogen Peroxide; Hydroxyl Radical; Iron; Macromolecular Substances; N-Glycosyl Hydrolases; Oxidation-Reduction; Piperidines; Protein Binding; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Substrate Specificity; Thymidine

2001
Age-related radical-induced DNA damage is linked to prostate cancer.
    Cancer research, 2001, Aug-15, Volume: 61, Issue:16

    Topics: Adenine; Age Factors; Cell Transformation, Neoplastic; DNA; DNA Damage; DNA, Neoplasm; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Hydroxyl Radical; Logistic Models; Male; Middle Aged; Models, Biological; Prostate; Prostatic Neoplasms; Pyrimidines

2001
Mechanisms of formation of 8-oxoguanine due to reactions of one and two OH* radicals and the H2O2 molecule with guanine: A quantum computational study.
    The journal of physical chemistry. B, 2005, Jul-28, Volume: 109, Issue:29

    Topics: Binding, Competitive; Computer Simulation; Guanine; Hydrogen Peroxide; Hydroxyl Radical; Models, Chemical; Models, Molecular; Molecular Structure; Quantum Theory; Thermodynamics

2005
Effect of amino acids on X-ray-induced hydrogen peroxide and hydroxyl radical formation in water and 8-oxoguanine in DNA.
    Biochemistry. Biokhimiia, 2008, Volume: 73, Issue:4

    Topics: Amino Acids; Antioxidants; DNA; DNA Damage; Free Radical Scavengers; Guanine; Hydrogen Peroxide; Hydroxyl Radical; Water; X-Rays

2008
Peculiarities of the antioxidant and radioprotective effects of hydrated C60 fullerene nanostuctures in vitro and in vivo.
    Free radical biology & medicine, 2009, Sep-15, Volume: 47, Issue:6

    Topics: Animals; Antioxidants; Apoptosis; Cell Line; Coumarins; DNA Damage; Free Radical Scavengers; Fullerenes; Guanine; Hydroxyl Radical; Injections, Intraperitoneal; Intestinal Mucosa; Male; Mice; Nanostructures; Nanotechnology; Oxidation-Reduction; Oxidative Stress; Radiation Injuries, Experimental; Radiation-Protective Agents; Radiation, Ionizing; Rats; Water; Weight Gain

2009
Oxidatively generated damage to DNA by UVA radiation in cells and human skin.
    The Journal of investigative dermatology, 2011, Volume: 131, Issue:5

    Topics: Cells, Cultured; DNA Breaks, Double-Stranded; DNA Damage; Guanine; Humans; Hydroxyl Radical; Oxidative Stress; Singlet Oxygen; Skin; Ultraviolet Rays

2011
Oxidation of the guanine nucleotide pool underlies cell death by bactericidal antibiotics.
    Science (New York, N.Y.), 2012, Apr-20, Volume: 336, Issue:6079

    Topics: Ampicillin; Anti-Bacterial Agents; Deoxyguanine Nucleotides; DNA Breaks, Double-Stranded; DNA Glycosylases; DNA Polymerase beta; DNA Polymerase I; DNA Polymerase II; DNA-Directed DNA Polymerase; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Guanine; Guanine Nucleotides; Hydroxyl Radical; Kanamycin; Microbial Viability; Models, Biological; Norfloxacin; Oxidation-Reduction; Pyrophosphatases; RNA, Bacterial

2012
Pro-oxidative, genotoxic and cytotoxic properties of uranyl ions.
    Journal of environmental radioactivity, 2014, Volume: 127

    Topics: Animals; Blood Proteins; Bone Marrow; DNA Damage; Guanine; Hot Temperature; Hydrogen Peroxide; Hydroxyl Radical; Ions; Lasers; Male; Mice; Mortality; Mutagenicity Tests; Reactive Oxygen Species; Uranium; Uranyl Nitrate; X-Rays

2014
Excess processing of oxidative damaged bases causes hypersensitivity to oxidative stress and low dose rate irradiation.
    Free radical research, 2015, Volume: 49, Issue:10

    Topics: Biomarkers; DNA Breaks, Double-Stranded; DNA Damage; DNA Glycosylases; DNA Repair; Enzyme Induction; Gamma Rays; Guanine; Heavy Ions; HeLa Cells; Histones; Humans; Hydrogen Peroxide; Hydroxyl Radical; Micronucleus Tests; Oxidative Stress; Radiation Tolerance; Recombinant Fusion Proteins; Transfection; Ultraviolet Rays

2015
A combinatorial role for MutY and Fpg DNA glycosylases in mutation avoidance in Mycobacterium smegmatis.
    Mutation research, 2015, Volume: 779

    Topics: DNA Glycosylases; DNA Repair; DNA-Formamidopyrimidine Glycosylase; Genome, Bacterial; Guanine; Hydroxyl Radical; Mutagenesis; Mutagens; Mutation; Mycobacterium smegmatis; Oxidative Stress; Pyrimidines

2015
Human Oxoguanine Glycosylase 1 Removes Solution Accessible 8-Oxo-7,8-dihydroguanine Lesions from Globally Substituted Nucleosomes Except in the Dyad Region.
    Biochemistry, 2018, 03-06, Volume: 57, Issue:9

    Topics: DNA; DNA Glycosylases; DNA Repair; Guanine; Humans; Hydroxyl Radical; Models, Molecular; Nucleosomes; Structure-Activity Relationship

2018
Does 8-Nitroguanine Form 8-Oxoguanine? An Insight from Its Reaction with
    The journal of physical chemistry. B, 2018, 02-15, Volume: 122, Issue:6

    Topics: Guanine; Hydroxyl Radical; Quantum Theory

2018