Page last updated: 2024-09-04

hydroxyl radical and 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid

hydroxyl radical has been researched along with 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid in 34 studies

Compound Research Comparison

Studies
(hydroxyl radical)
Trials
(hydroxyl radical)
Recent Studies (post-2010)
(hydroxyl radical)
Studies
(6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid)
Trials
(6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid)
Recent Studies (post-2010) (6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid)
10,147263,6571,54116580

Protein Interaction Comparison

ProteinTaxonomyhydroxyl radical (IC50)6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (IC50)
Prostaglandin G/H synthase 1Homo sapiens (human)0.13
Prostaglandin G/H synthase 2Homo sapiens (human)0.15

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (17.65)18.2507
2000's20 (58.82)29.6817
2010's8 (23.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miura, T; Muraoka, S; Ogiso, T1
Burkitt, MJ; Milne, L1
Hiramoto, K; Kikugawa, K; Ojima, N1
Abadie, C; Lecour, S; Maupoil, V; Rochette, L; Vergely, C; Walker, MK1
Chen, C; Hou, J; Li, F; Mori, A; Wei, T; Xin, W; Zhao, B1
Huguet, F; Piriou, A; Pontcharraud, R; Remblier, C; Tallineau, C1
Acuña-Castroviejo, D; Escames, G; Khaldy, H; León, J; Luna, JD; Vives, F1
Afeworki, M; Brechbiel, MW; DeGraff, W; Krishna, MC; Mitchell, JB; Samuni, AM; Stein, W; Yordanov, AT1
Anderson, RF; Fisher, LJ; Harris, T1
Lemańska, K; Rietjens, IM; Soffers, AE; Szymusiak, H; Tyrakowska, B; Zieliński, R1
Aime, S; Baroni, S; Bruno, E; Digilio, G; Fasano, M; Mainero, V1
Calomme, M; Cos, P; De Bruyne, T; Hermans, N; Maes, L; Pieters, L; Vanden Berghe, D; Vlietinck, AJ1
Choi, JS; Chung, HY; Jung, HA; Jung, MJ; Kim, JY1
Mizuno, M; Nishizawa, C; Ozawa, T; Suzuki, KT; Takeshita, K; Ueda, J1
Frega, N; Jiménez, AM; Martínez-Tomé, M; Murcia, MA; Parras, P; Roses, F; Ruggieri, S1
Huang, D; Ou, B; Prior, RL1
Balogh, GT; Fischer, J; Gere, A; Kis-Varga, A; Könczöl, A; Vukics, K1
Poljsak, B; Raspor, P1
Kang, KS; Kim, HY; Okamoto, T; Sei, Y; Yamabe, N; Yokozawa, T1
Aboy, AL; Bassani, VL; Behr, GA; Bordignon, CL; Dal-Pizzol, F; Henriques, AT; Lorenzi, R; Moreira, JC; Pasquali, MA; Ravazolo, LG; Reginatto, FH; Silva, EG; Silva, FA; Zanotto-Filho, A1
Mankura, M; Noda, Y1
Hara, H; Inokuchi, Y; Ishibashi, T; Nakajima, Y; Otsubo, K; Shimazawa, M1
Abderrahim, F; Arribas, SM; Conde, MV; Condezo-Hoyos, L; Díaz-Gil, JJ; González, MC; Susín, C1
Fang, TJ; Sheih, IC; Wu, TK1
García-Diz, L; Jiménez-Monreal, AM; Mariscal, M; Martínez-Tomé, M; Murcia, MA1
Chang, SC; Chen, BH; Inbaraj, BS; Lin, CL; Wang, CC1
Hrabárová, E; Rapta, P; Soltés, L; Valachová, K1
Apak, R; Bener, M; Güçlü, K; Ozyürek, M; Türkkan, B1
Chen, TQ; Liao, LM; Wong, KH; Wu, JG; Wu, JZ; Zeng, PY1
Cherdkiatikul, T; Suwanwong, Y1
Galano, A; Marino, T; Russo, N1
Bento, F; Geraldo, D; Oliveira, R1
Bereau, D; Brunschwig, C; Leba, LJ; Martial, K; Robinson, JC; Saout, M; Vulcain, E1
Jiang, Y; Liu, H; Tian, M; Wen, L; Yang, B; Yang, J; Yu, L; Zeng, X; Zhao, Y1

Reviews

1 review(s) available for hydroxyl radical and 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid

ArticleYear
The chemistry behind antioxidant capacity assays.
    Journal of agricultural and food chemistry, 2005, Mar-23, Volume: 53, Issue:6

    Topics: Antioxidants; Chromans; Copper; Ferric Compounds; Free Radical Scavengers; Free Radicals; Hydrogen Peroxide; Hydroxyl Radical; Kinetics; Lipid Peroxidation; Molybdenum; Oxidation-Reduction; Oxygen; Peroxynitrous Acid; Phenols; Reactive Oxygen Species; Singlet Oxygen; Tungsten Compounds

2005

Other Studies

33 other study(ies) available for hydroxyl radical and 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid

ArticleYear
Inhibition of hydroxyl radical-induced protein damages by trolox.
    Biochemistry and molecular biology international, 1993, Volume: 31, Issue:1

    Topics: Aerobiosis; Anaerobiosis; Antioxidants; Ascorbic Acid; Chromans; Creatine Kinase; Dose-Response Relationship, Drug; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Ferric Compounds; Hydrogen Peroxide; Hydroxyl Radical; L-Lactate Dehydrogenase; Oxidation-Reduction; Proteins; Serum Albumin, Bovine

1993
Hydroxyl radical formation from Cu(II)-trolox mixtures: insights into the pro-oxidant properties of alpha-tocopherol.
    FEBS letters, 1996, Jan-22, Volume: 379, Issue:1

    Topics: Antioxidants; Chromans; Copper; Electron Spin Resonance Spectroscopy; Hydroxyl Radical; In Vitro Techniques; Lipoproteins, LDL; Oxidants; Oxidation-Reduction; Oxygen Consumption; Vitamin E

1996
Conversion of nitroxide radicals by phenolic and thiol antioxidants.
    Free radical research, 1997, Volume: 27, Issue:1

    Topics: Antioxidants; Chromans; Cyclic N-Oxides; Cysteine; Dimethyl Sulfoxide; Electron Spin Resonance Spectroscopy; Ethanol; Free Radical Scavengers; Free Radicals; Glutathione; Hydroxyl Radical; Mercaptoethanol; Metallothionein; Nitrogen Oxides; Phenols; Sulfhydryl Compounds

1997
Vitamin E analogues reduce the incidence of ventricular fibrillations and scavenge free radicals.
    Fundamental & clinical pharmacology, 1998, Volume: 12, Issue:2

    Topics: Animals; Antioxidants; Arrhythmias, Cardiac; Benzopyrans; Chromans; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Heart Rate; Hydroxyl Radical; In Vitro Techniques; Male; Phycoerythrin; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxides; Ventricular Fibrillation; Vitamin E

1998
Antioxidant properties of EPC-K1: a study on mechanisms.
    Biophysical chemistry, 1999, Mar-29, Volume: 77, Issue:2-3

    Topics: Animals; Antioxidants; Ascorbic Acid; Brain; Chromans; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Hydroxyl Radical; Linoleic Acid; Lipid Peroxidation; Male; Molecular Structure; Peroxides; Pulse Radiolysis; Rats; Rats, Wistar; Spectrophotometry; Structure-Activity Relationship; Vitamin E

1999
Lactic acid-induced increase of extracellular dopamine measured by microdialysis in rat striatum: evidence for glutamatergic and oxidative mechanisms.
    Brain research, 1999, Aug-07, Volume: 837, Issue:1-2

    Topics: Acidosis, Lactic; Animals; Antioxidants; Chromans; Chromatography, High Pressure Liquid; Corpus Striatum; Dizocilpine Maleate; Dopamine; Electrochemistry; Gentisates; Glutamic Acid; Hydrogen-Ion Concentration; Hydroxybenzoates; Hydroxyl Radical; Kinetics; Lactic Acid; Male; Microdialysis; Rats; Rats, Sprague-Dawley

1999
Comparative effects of melatonin, L-deprenyl, Trolox and ascorbate in the suppression of hydroxyl radical formation during dopamine autoxidation in vitro.
    Journal of pineal research, 2000, Volume: 29, Issue:2

    Topics: Antioxidants; Ascorbic Acid; Chromans; Dopamine; Dose-Response Relationship, Drug; Hydroxybenzoates; Hydroxyl Radical; Iron; Melatonin; Oxidation-Reduction; Salicylates; Selegiline

2000
Multifunctional antioxidant activity of HBED iron chelator.
    Free radical biology & medicine, 2001, Jan-15, Volume: 30, Issue:2

    Topics: Animals; Antioxidants; Benzothiazoles; Cell Death; Cell Line; Cell Survival; Chromans; Cricetinae; Cricetulus; Cyclic N-Oxides; Cytoprotection; Edetic Acid; Electron Spin Resonance Spectroscopy; Hydrogen; Hydrogen Peroxide; Hydroxyl Radical; Iron Chelating Agents; Oxidation-Reduction; Oxygen; Phenols; Spectrophotometry; Spin Labels; Sulfonic Acids; Superoxides; tert-Butylhydroperoxide

2001
The 'pivotal antioxidant' hypothesis for the role of flavonoids in their reduction of HO* radical-induced damage on DNA.
    Redox report : communications in free radical research, 2001, Volume: 6, Issue:3

    Topics: Antioxidants; Ascorbic Acid; Catechin; Chromans; DNA Damage; DNA, Bacterial; Flavonoids; Gamma Rays; Glutathione; Hydroxyl Radical; Models, Biological; Oxidants; Oxidation-Reduction

2001
The influence of pH on antioxidant properties and the mechanism of antioxidant action of hydroxyflavones.
    Free radical biology & medicine, 2001, Oct-01, Volume: 31, Issue:7

    Topics: Antioxidants; Benzothiazoles; Chromans; Electron Transport; Flavonoids; Free Radical Scavengers; Hydrogen; Hydrogen-Ion Concentration; Hydroxyl Radical; Kinetics; Quantitative Structure-Activity Relationship; Sulfonic Acids; Thermodynamics

2001
Modulation of the antioxidant activity of HO* scavengers by albumin binding: a 19F-NMR study.
    Biochemical and biophysical research communications, 2003, Aug-08, Volume: 307, Issue:4

    Topics: Acetamides; Aminophenols; Antioxidants; Binding, Competitive; Chromans; Fluorine Radioisotopes; Fluoroacetates; Free Radical Scavengers; Hydroxyl Radical; Nuclear Magnetic Resonance, Biomolecular; Serum Albumin, Bovine; Trifluoroacetic Acid

2003
Comparative study of eight well-known polyphenolic antioxidants.
    The Journal of pharmacy and pharmacology, 2003, Volume: 55, Issue:9

    Topics: Antioxidants; Benzoates; Biflavonoids; Biphenyl Compounds; Catechin; Cell Survival; Cells, Cultured; Chromans; Cinnamates; Dose-Response Relationship, Drug; Fibroblasts; Flavonoids; Free Radicals; Genistein; Humans; Hydrazines; Hydroxyl Radical; Lipid Peroxidation; Phenols; Picrates; Polyphenols; Proanthocyanidins; Skin; Stilbenes

2003
Inhibitory activity of flavonoids from Prunus davidiana and other flavonoids on total ROS and hydroxyl radical generation.
    Archives of pharmacal research, 2003, Volume: 26, Issue:10

    Topics: 1-Butanol; Acetates; Animals; Antioxidants; Ascorbic Acid; Biphenyl Compounds; Catechin; Chromans; Drug Evaluation, Preclinical; Flavonoids; Free Radical Scavengers; Hesperidin; Hydrazines; Hydroxyl Radical; Kaempferols; Kidney; Male; Methanol; Methylene Chloride; Penicillamine; Peroxynitrous Acid; Picrates; Plant Extracts; Plant Stems; Prunus; Rats; Rats, Wistar; Reactive Oxygen Species; Structure-Activity Relationship; Water

2003
Hydroxyl radical generation caused by the reaction of singlet oxygen with a spin trap, DMPO, increases significantly in the presence of biological reductants.
    Free radical research, 2004, Volume: 38, Issue:4

    Topics: Antioxidants; Ascorbic Acid; Azides; Chromans; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Ethanol; Glutathione; Hydroxyl Radical; Manganese; Oxygen; Reactive Oxygen Species; Salicylic Acid; Spin Trapping; Superoxides

2004
Evaluation of antioxidant capacity of cereal brans.
    Journal of agricultural and food chemistry, 2004, Jul-28, Volume: 52, Issue:15

    Topics: Antioxidants; Avena; Chromans; Deoxyribose; Dietary Fiber; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Linoleic Acid; Lipid Peroxidation; Oxidation-Reduction; Peroxides; Phospholipids

2004
Nitrone derivatives of trolox as neuroprotective agents.
    Bioorganic & medicinal chemistry letters, 2005, Jun-15, Volume: 15, Issue:12

    Topics: Animals; Antioxidants; Arterial Occlusive Diseases; Brain Ischemia; Cerebrovascular Circulation; Chromans; Free Radical Scavengers; Hydroxyl Radical; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Mice; Neuroprotective Agents; Nitrogen Oxides; Structure-Activity Relationship

2005
The antioxidant and pro-oxidant activity of vitamin C and trolox in vitro: a comparative study.
    Journal of applied toxicology : JAT, 2008, Volume: 28, Issue:2

    Topics: Antioxidants; Ascorbic Acid; Chromans; Chromium; DNA Damage; DNA, Superhelical; Hydrogen Peroxide; Hydroxyl Radical; Oxidants; Oxidation-Reduction; Plasmids

2008
Increase in the free radical scavenging activities of American ginseng by heat processing and its safety evaluation.
    Journal of ethnopharmacology, 2007, Sep-05, Volume: 113, Issue:2

    Topics: Administration, Oral; Animals; Biphenyl Compounds; Chromans; Dose-Response Relationship, Drug; Free Radical Scavengers; Ginsenosides; Glycosylation; Hot Temperature; Hydrazines; Hydroxyl Radical; Kidney; Liver; Maillard Reaction; Male; Nitric Oxide; Organ Size; Panax; Peroxynitrous Acid; Phenols; Phycocyanin; Picrates; Plant Extracts; Rats; Rats, Wistar; Superoxides; Weight Gain

2007
Antioxidant activities and free radical scavenging potential of Bauhinia microstachya (RADDI) MACBR. (Caesalpinaceae) extracts linked to their polyphenol content.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:8

    Topics: Antioxidants; Bauhinia; Chromans; Chromatography, High Pressure Liquid; Ethanol; Flavonoids; Free Radical Scavengers; Hydroxyl Radical; Luminescence; Nitric Oxide; Phenols; Plant Extracts; Plant Leaves; Polyphenols; Solvents; Spectrophotometry, Ultraviolet; Superoxides; Thiobarbituric Acid Reactive Substances; Water; Xanthine Oxidase

2007
Inhibitory effect of antioxidants on hydroxyl radical generation from methylguanidine: an ESR study.
    Neurochemical research, 2009, Volume: 34, Issue:4

    Topics: Antioxidants; Ascorbic Acid; Chromans; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Glutathione; Hydroxyl Radical; Methylguanidine; Spin Trapping; Vitamin E

2009
Astaxanthin, a dietary carotenoid, protects retinal cells against oxidative stress in-vitro and in mice in-vivo.
    The Journal of pharmacy and pharmacology, 2008, Volume: 60, Issue:10

    Topics: Animals; Apoptosis; Carrier Proteins; Cell Survival; Cells, Cultured; Chromans; Dose-Response Relationship, Drug; Ferric Compounds; Fluoresceins; Hydrogen Peroxide; Hydroxyl Radical; In Situ Nick-End Labeling; Lipid Peroxidation; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Oxidative Stress; Phosphate-Binding Proteins; Rats; Reactive Oxygen Species; Retina; Retinal Diseases; Retinal Ganglion Cells; Xanthophylls

2008
Antioxidant activity of liver growth factor, a bilirubin covalently bound to albumin.
    Free radical biology & medicine, 2009, Mar-01, Volume: 46, Issue:5

    Topics: Animals; Antioxidants; Benzothiazoles; Bilirubin; Blood Pressure Determination; Carotid Arteries; Chromans; Endothelial Cells; Fibrosis; Hydroxyl Radical; Hypertension; Male; Nitric Oxide; Oxidative Stress; Peroxides; Protein Binding; Rats; Rats, Sprague-Dawley; Serum Albumin; Serum Albumin, Bovine; Serum Albumin, Human; Sulfonic Acids

2009
Antioxidant properties of a new antioxidative peptide from algae protein waste hydrolysate in different oxidation systems.
    Bioresource technology, 2009, Volume: 100, Issue:13

    Topics: Antioxidants; Biotechnology; Biphenyl Compounds; Cell Line, Tumor; Chlorella vulgaris; Chromans; DNA Damage; Eukaryota; Fibroblasts; Humans; Hydroxyl Radical; Inhibitory Concentration 50; Oxygen; Peptides; Picrates; Plant Extracts

2009
Influence of cooking methods on antioxidant activity of vegetables.
    Journal of food science, 2009, Volume: 74, Issue:3

    Topics: Antioxidants; Apium; Benzothiazoles; Chromans; Cooking; Daucus carota; Fabaceae; Free Radical Scavengers; Hot Temperature; Hydroxyl Radical; Lipid Peroxidation; Lipid Peroxides; Microwaves; Pressure; Sulfonic Acids; Vegetables; Water

2009
Antioxidative activity of polysaccharide fractions isolated from Lycium barbarum Linnaeus.
    International journal of biological macromolecules, 2009, Aug-01, Volume: 45, Issue:2

    Topics: Biphenyl Compounds; Chelating Agents; Chromans; Drugs, Chinese Herbal; Free Radical Scavengers; Hydroxyl Radical; Iron; Lycium; Oxidation-Reduction; Picrates; Superoxides

2009
An alternative standard for Trolox-equivalent antioxidant-capacity estimation based on thiol antioxidants. Comparative 2,2'-azinobis[3-ethylbenzothiazoline-6-sulfonic acid] decolorization and rotational viscometry study regarding hyaluronan degradation.
    Chemistry & biodiversity, 2010, Volume: 7, Issue:9

    Topics: Antioxidants; Benzothiazoles; Chromans; Dithioerythritol; Drug Evaluation, Preclinical; Free Radical Scavengers; Glutathione; Hyaluronic Acid; Hydroxyl Radical; Oxidation-Reduction; Penicillamine; Solubility; Solvents; Spectrophotometry; Structure-Activity Relationship; Sulfhydryl Compounds; Sulfonic Acids; Thiazoles; Viscosity

2010
Synthesis, characterization and antioxidant capacity of naringenin-oxime.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2012, Volume: 85, Issue:1

    Topics: Antioxidants; Chromans; Citrus; Flavanones; Hydrogen Peroxide; Hydroxyl Radical; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Oximes; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Superoxides

2012
In vitro antioxidant activities of endophytic fungi isolated from the liverwort Scapania verrucosa.
    Genetics and molecular research : GMR, 2011, Dec-20, Volume: 10, Issue:4

    Topics: Acetates; Antioxidants; Benzothiazoles; Biphenyl Compounds; China; Chromans; Complex Mixtures; Endophytes; Free Radical Scavengers; Free Radicals; Fungi; Genes, Fungal; Genes, rRNA; Hepatophyta; Hydroxyl Radical; Iron Chelating Agents; Oxidation-Reduction; Picrates; Solvents; Sulfonic Acids

2011
Production of the α and β Subunits of Spirulina Allophycocyanin and C-Phycocyanin in Escherichia coli : A Comparative Study of Their Antioxidant Activities.
    Journal of biomolecular screening, 2014, Volume: 19, Issue:6

    Topics: Antioxidants; Chromans; DNA Primers; Escherichia coli; Free Radicals; Genetic Vectors; Hydroxyl Radical; Inhibitory Concentration 50; Oxygen; Phycocyanin; Plasmids; Recombinant Proteins; Reproducibility of Results; Spirulina

2014
Radical scavenging ability of gallic acid toward OH and OOH radicals. Reaction mechanism and rate constants from the density functional theory.
    The journal of physical chemistry. B, 2014, Sep-04, Volume: 118, Issue:35

    Topics: Benzene; Chromans; Computer Simulation; Diffusion; Electrons; Free Radical Scavengers; Gallic Acid; Hydrogen-Ion Concentration; Hydroxyl Radical; Lipids; Models, Chemical; Molecular Structure; Peroxides; Quantum Theory; Reactive Nitrogen Species; Solvents; Water

2014
Radical scavenging activity of antioxidants evaluated by means of electrogenerated HO radical.
    Talanta, 2014, Volume: 129

    Topics: Antioxidants; Ascorbic Acid; Beverages; Caffeic Acids; Chromans; Chromatography, High Pressure Liquid; Electrochemistry; Electrolysis; Food Analysis; Free Radical Scavengers; Gallic Acid; Hydroxyl Radical; Oxygen; Phenol; Tea

2014
Optimization of a DNA nicking assay to evaluate Oenocarpus bataua and Camellia sinensis antioxidant capacity.
    International journal of molecular sciences, 2014, Oct-09, Volume: 15, Issue:10

    Topics: Antioxidants; Arecaceae; Camellia sinensis; Chromans; Deoxyribonuclease I; DNA Breaks, Single-Stranded; Enzyme Assays; Gallic Acid; Hydroxyl Radical; Plant Extracts; Plant Leaves; Plasmids; Quercetin

2014
Identification of a flavonoid C-glycoside as potent antioxidant.
    Free radical biology & medicine, 2017, Volume: 110

    Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Apigenin; Artocarpus; Biphenyl Compounds; Cell Proliferation; Cell Survival; Chromans; Dose-Response Relationship, Drug; Flavonoids; Glycosides; Hep G2 Cells; Humans; Hydroxyl Radical; MCF-7 Cells; Monosaccharides; Picrates; Plant Extracts; Plant Leaves; Quercetin

2017