Page last updated: 2024-09-04

hydroxyl radical and 3-nitropropionic acid

hydroxyl radical has been researched along with 3-nitropropionic acid in 10 studies

Compound Research Comparison

Studies
(hydroxyl radical)
Trials
(hydroxyl radical)
Recent Studies (post-2010)
(hydroxyl radical)
Studies
(3-nitropropionic acid)
Trials
(3-nitropropionic acid)
Recent Studies (post-2010) (3-nitropropionic acid)
10,147263,6579701327

Protein Interaction Comparison

ProteinTaxonomyhydroxyl radical (IC50)3-nitropropionic acid (IC50)
Isocitrate lyaseCandida albicans7.5

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (60.00)18.2507
2000's3 (30.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Beal, MF; Chan, PH; Epstein, CJ; Ferrante, RJ; Henshaw, R; Kowall, NW; Matthews, RT; Schulz, JB1
Beal, MF; Henshaw, DR; MacGarvey, U; Schulz, JB1
Beal, MF; Dichgans, J; Klockgether, T; Matthews, RT; Schulz, JB1
Beal, MF; Bogdanov, MB; Ramos, LE; Xu, Z1
Beal, MF; Bogdanov, MB; Ferrante, RJ; Klivenyi, P; Kuemmerle, S1
Cheng, FC; Dryhurst, G; Han, J; Yang, Z1
Albers, DW; Andreassen, OA; Beal, MF; Carlson, EJ; Dedeoglu, A; Epstein, CJ; Ferrante, RJ; Klivenyi, P1
Camacho, A; Flores, A; Galván-Arzate, S; Jiménez-Capdeville, ME; Rodríguez-Martínez, E; Santamaría, A1
Barman, PK; Borah, A; Mohanakumar, KP; Pandey, M; Usha, R; Varghese, M1
Gopinath, K; Sudhandiran, G1

Reviews

1 review(s) available for hydroxyl radical and 3-nitropropionic acid

ArticleYear
The role of mitochondrial dysfunction and neuronal nitric oxide in animal models of neurodegenerative diseases.
    Molecular and cellular biochemistry, 1997, Volume: 174, Issue:1-2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Disease Models, Animal; Dopamine Agents; Hydroxyl Radical; Mice; Mitochondria; Neurodegenerative Diseases; Nitric Oxide; Nitro Compounds; Primates; Propionates; Rats

1997

Other Studies

9 other study(ies) available for hydroxyl radical and 3-nitropropionic acid

ArticleYear
3-Nitropropionic acid neurotoxicity is attenuated in copper/zinc superoxide dismutase transgenic mice.
    Journal of neurochemistry, 1995, Volume: 65, Issue:2

    Topics: Animals; Humans; Hydroxybenzoates; Hydroxyl Radical; Mice; Mice, Transgenic; Neurotoxins; Nitro Compounds; Propionates; Reference Values; Superoxide Dismutase; Tyrosine

1995
Involvement of oxidative stress in 3-nitropropionic acid neurotoxicity.
    Neurochemistry international, 1996, Volume: 29, Issue:2

    Topics: Animals; Benzenesulfonates; Cyclic N-Oxides; Hydroxyl Radical; Male; Nervous System Diseases; Nitro Compounds; Nitrogen Oxides; Oxidative Stress; Propionates; Rats; Rats, Sprague-Dawley; Spin Labels

1996
Elevated "hydroxyl radical" generation in vivo in an animal model of amyotrophic lateral sclerosis.
    Journal of neurochemistry, 1998, Volume: 71, Issue:3

    Topics: Amyotrophic Lateral Sclerosis; Animals; Corpus Striatum; Humans; Hydroxybenzoates; Hydroxyl Radical; Mice; Mice, Transgenic; Microdialysis; Neurotoxins; Nitro Compounds; Parabens; Propionates; Superoxide Dismutase; Superoxide Dismutase-1

1998
Increased vulnerability to 3-nitropropionic acid in an animal model of Huntington's disease.
    Journal of neurochemistry, 1998, Volume: 71, Issue:6

    Topics: Animals; Corpus Striatum; Drug Resistance; Huntington Disease; Hydroxybenzoates; Hydroxyl Radical; Mice; Mice, Transgenic; Microdialysis; Nitro Compounds; Parabens; Propionates; Reference Values

1998
Inhibitors of mitochondrial respiration, iron (II), and hydroxyl radical evoke release and extracellular hydrolysis of glutathione in rat striatum and substantia nigra: potential implications to Parkinson's disease.
    Journal of neurochemistry, 1999, Volume: 73, Issue:4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Corpus Striatum; Cysteine; Glutamic Acid; Glutathione; Glycine; Hydrolysis; Hydroxyl Radical; Iron; Kinetics; Male; Microdialysis; Mitochondria; Models, Chemical; Nitro Compounds; Oxygen Consumption; Parkinson Disease; Perfusion; Propionates; Rats; Rats, Sprague-Dawley; Substantia Nigra

1999
Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP.
    Experimental neurology, 2001, Volume: 167, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Carrier Proteins; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Genetic Predisposition to Disease; Gentisates; Heterozygote; Homovanillic Acid; Hydroxybenzoates; Hydroxyl Radical; Male; Malonates; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Knockout; Mitochondria; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurotoxins; Nitro Compounds; Propionates; Salicylic Acid; Superoxide Dismutase

2001
In vivo hydroxyl radical formation after quinolinic acid infusion into rat corpus striatum.
    Neuroreport, 2001, Aug-28, Volume: 12, Issue:12

    Topics: Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutathione; Glutathione Peroxidase; Hydroxybenzoates; Hydroxyl Radical; Lipid Peroxidation; Male; Microdialysis; Microinjections; Neuroprotective Agents; Nitro Compounds; Oxidative Stress; Perfusion; Propionates; Quinolinic Acid; Rats; Rats, Wistar; Salicylic Acid; Wakefulness

2001
Striatal dopamine level contributes to hydroxyl radical generation and subsequent neurodegeneration in the striatum in 3-nitropropionic acid-induced Huntington's disease in rats.
    Neurochemistry international, 2009, Volume: 55, Issue:6

    Topics: Animals; Convulsants; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Huntington Disease; Hydroxyl Radical; Lameness, Animal; Levodopa; Male; Mitochondria; Nerve Degeneration; Neurotoxins; Nitro Compounds; Oxidative Phosphorylation; Oxidative Stress; Propionates; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase

2009
Naringin modulates oxidative stress and inflammation in 3-nitropropionic acid-induced neurodegeneration through the activation of nuclear factor-erythroid 2-related factor-2 signalling pathway.
    Neuroscience, 2012, Dec-27, Volume: 227

    Topics: Administration, Oral; Analysis of Variance; Animals; Convulsants; Corpus Striatum; Cyclooxygenase 2; Disease Models, Animal; Down-Regulation; Encephalitis; Flavanones; Glutathione; Glutathione Disulfide; Hydrogen Peroxide; Hydroxyl Radical; Male; Microscopy, Electron, Transmission; NAD(P)H Dehydrogenase (Quinone); Neurodegenerative Diseases; Neuroprotective Agents; NF-E2-Related Factor 2; Nitric Oxide Synthase Type II; Nitro Compounds; Oxidative Stress; Propionates; Rats; Rats, Wistar; RNA, Messenger; Signal Transduction; Tumor Necrosis Factor-alpha

2012