hydroxyitraconazole has been researched along with posaconazole in 7 studies
| Studies (hydroxyitraconazole) | Trials (hydroxyitraconazole) | Recent Studies (post-2010) (hydroxyitraconazole) | Studies (posaconazole) | Trials (posaconazole) | Recent Studies (post-2010) (posaconazole) |
|---|---|---|---|---|---|
| 87 | 29 | 22 | 1,575 | 103 | 1,014 |
| Protein | Taxonomy | hydroxyitraconazole (IC50) | posaconazole (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 8.1 | |
| Steroid 17-alpha-hydroxylase/17,20 lyase | Homo sapiens (human) | 0.921 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.2458 | |
| Aromatase | Homo sapiens (human) | 8.4 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 7.2 | |
| Cytochrome P450 11B1, mitochondrial | Homo sapiens (human) | 0.31 | |
| Cytochrome P450 11B2, mitochondrial | Homo sapiens (human) | 0.021 | |
| Sterol 14-alpha demethylase | Trypanosoma cruzi strain CL Brener | 0.464 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 6 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Aarnoutse, RE; Brüggemann, RJ; Burger, DM; Touw, DJ; Verweij, PE | 1 |
| Bille, J; Calandra, T; Decosterd, LA; Marchetti, O; Mercier, T; Pesse, B; Rochat, B; Tissot, F; Widmer, N; Zanolari, B | 1 |
| Buckner, SL; Ceesay, MM; Flanagan, RJ; Morgan, PE; Pagliuca, A | 1 |
| Barclay, ML; Begg, EJ; Moore, GA; Zhang, M | 1 |
| Aarnoutse, RE; Brüggemann, RJ; Burger, DM; Koenderink, JB; Lempers, VJ; Russel, FG; van den Heuvel, JJ | 1 |
| Basu, SS; Jarolim, P; Mason, DS; Petrides, A | 1 |
| Bazydlo, L; Girton, M; Tomsig, J | 1 |
1 trial(s) available for hydroxyitraconazole and posaconazole
| Article | Year |
|---|---|
Measurement of posaconazole, itraconazole, and hydroxyitraconazole in plasma/serum by high-performance liquid chromatography with fluorescence detection.
Topics: Adult; Aged; Antifungal Agents; Calibration; Chromatography, High Pressure Liquid; Cohort Studies; Dose-Response Relationship, Drug; Drug Monitoring; Female; Humans; Invasive Pulmonary Aspergillosis; Itraconazole; Limit of Detection; Male; Middle Aged; Neutropenia; Reproducibility of Results; Spectrometry, Fluorescence; Triazoles; Young Adult | 2011 |
6 other study(ies) available for hydroxyitraconazole and posaconazole
| Article | Year |
|---|---|
International interlaboratory proficiency testing program for measurement of azole antifungal plasma concentrations.
Topics: Antifungal Agents; Azoles; Biological Assay; Fluconazole; Humans; Itraconazole; Pyrimidines; Triazoles; Voriconazole | 2009 |
Multiplex ultra-performance liquid chromatography-tandem mass spectrometry method for simultaneous quantification in human plasma of fluconazole, itraconazole, hydroxyitraconazole, posaconazole, voriconazole, voriconazole-N-oxide, anidulafungin, and caspo
Topics: Anidulafungin; Antifungal Agents; Blood Chemical Analysis; Caspofungin; Chromatography, Liquid; Echinocandins; Humans; Itraconazole; Lipopeptides; Pyrimidines; Tandem Mass Spectrometry; Triazoles; Voriconazole | 2010 |
A simple high-performance liquid chromatography method for simultaneous determination of three triazole antifungals in human plasma.
Topics: Antifungal Agents; Calibration; Chromatography, High Pressure Liquid; Humans; Itraconazole; Limit of Detection; Naproxen; Observer Variation; Pyrimidines; Reference Standards; Reproducibility of Results; Triazoles; Voriconazole | 2013 |
Inhibitory Potential of Antifungal Drugs on ATP-Binding Cassette Transporters P-Glycoprotein, MRP1 to MRP5, BCRP, and BSEP.
Topics: Amphotericin B; Antifungal Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Echinocandins; Fluconazole; HEK293 Cells; Humans; Itraconazole; Lipopeptides; Micafungin; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Triazoles; Voriconazole | 2016 |
A rapid UPLC-MS/MS assay for the simultaneous measurement of fluconazole, voriconazole, posaconazole, itraconazole, and hydroxyitraconazole concentrations in serum.
Topics: Antifungal Agents; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Fluconazole; Humans; Itraconazole; Limit of Detection; Reproducibility of Results; Tandem Mass Spectrometry; Time Factors; Triazoles; Voriconazole | 2017 |
Triazole Antifungal Quantification for Therapeutic Drug Monitoring in Serum by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS): Posaconazole, Voriconazole, Itraconazole, and Hydroxyitraconazole.
Topics: Antifungal Agents; Chromatography, High Pressure Liquid; Chromatography, Liquid; Drug Monitoring; Itraconazole; Methanol; Reproducibility of Results; Tandem Mass Spectrometry; Triazoles; Voriconazole | 2024 |