hydroxyitraconazole has been researched along with fluconazole in 4 studies
| Studies (hydroxyitraconazole) | Trials (hydroxyitraconazole) | Recent Studies (post-2010) (hydroxyitraconazole) | Studies (fluconazole) | Trials (fluconazole) | Recent Studies (post-2010) (fluconazole) |
|---|---|---|---|---|---|
| 87 | 29 | 22 | 9,343 | 721 | 3,664 |
| Protein | Taxonomy | hydroxyitraconazole (IC50) | fluconazole (IC50) |
|---|---|---|---|
| Lanosterol 14-alpha demethylase | Candida albicans SC5314 | 0.1296 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 9.21 | |
| Sterol 14-alpha demethylase | Trypanosoma cruzi strain CL Brener | 0.88 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aarnoutse, RE; Brüggemann, RJ; Burger, DM; Touw, DJ; Verweij, PE | 1 |
| Backman, JT; Karonen, T; Laitila, J; Neuvonen, PJ; Niemi, M | 1 |
| Aarnoutse, RE; Brüggemann, RJ; Burger, DM; Koenderink, JB; Lempers, VJ; Russel, FG; van den Heuvel, JJ | 1 |
| Basu, SS; Jarolim, P; Mason, DS; Petrides, A | 1 |
1 trial(s) available for hydroxyitraconazole and fluconazole
| Article | Year |
|---|---|
Fluconazole but not the CYP3A4 inhibitor, itraconazole, increases zafirlukast plasma concentrations.
Topics: Adult; Anti-Asthmatic Agents; Antifungal Agents; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cross-Over Studies; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Enzyme Inhibitors; Female; Fluconazole; Genetic Association Studies; Half-Life; Humans; Indoles; Itraconazole; Leukotriene Antagonists; Male; Phenylcarbamates; Polymorphism, Genetic; Sulfonamides; Tosyl Compounds; Young Adult | 2012 |
3 other study(ies) available for hydroxyitraconazole and fluconazole
| Article | Year |
|---|---|
International interlaboratory proficiency testing program for measurement of azole antifungal plasma concentrations.
Topics: Antifungal Agents; Azoles; Biological Assay; Fluconazole; Humans; Itraconazole; Pyrimidines; Triazoles; Voriconazole | 2009 |
Inhibitory Potential of Antifungal Drugs on ATP-Binding Cassette Transporters P-Glycoprotein, MRP1 to MRP5, BCRP, and BSEP.
Topics: Amphotericin B; Antifungal Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Echinocandins; Fluconazole; HEK293 Cells; Humans; Itraconazole; Lipopeptides; Micafungin; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Triazoles; Voriconazole | 2016 |
A rapid UPLC-MS/MS assay for the simultaneous measurement of fluconazole, voriconazole, posaconazole, itraconazole, and hydroxyitraconazole concentrations in serum.
Topics: Antifungal Agents; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Fluconazole; Humans; Itraconazole; Limit of Detection; Reproducibility of Results; Tandem Mass Spectrometry; Time Factors; Triazoles; Voriconazole | 2017 |