Compounds > hydroxyindoleacetic acid

hydroxyindoleacetic acid and vadimezan

hydroxyindoleacetic acid has been researched along with vadimezan in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's4 (66.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baguley, BC; Kestell, P; Zhuang, L1
Baguley, BC; Folkes, LK; Jameson, MB; Kestell, P; Stratford, MR; Zhao, L1
Baguley, BC; Ching, LM; Kestell, P; Zhao, L1
Baguley, BC; Ching, LM1
Baguley, BC; Baker, SD; Jameson, MB; Li, J; Pili, R1
Cao, N; Du, G; Duan, Y; Guo, Z; Han, G; Li, G; Li, H; Lin, H; Liu, L; Ma, X1

Trials

1 trial(s) available for hydroxyindoleacetic acid and vadimezan

ArticleYear
Population pharmacokinetic-pharmacodynamic model of the vascular-disrupting agent 5,6-dimethylxanthenone-4-acetic acid in cancer patients.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Apr-01, Volume: 14, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents; Area Under Curve; Blood Vessels; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Neoplasms; Nonlinear Dynamics; Xanthones

2008

Other Studies

5 other study(ies) available for hydroxyindoleacetic acid and vadimezan

ArticleYear
Increased plasma serotonin following treatment with flavone-8-acetic acid, 5,6-dimethylxanthenone-4-acetic acid, vinblastine, and colchicine: relation to vascular effects.
    Oncology research, 1997, Volume: 9, Issue:2

    Topics: Animals; Antineoplastic Agents; Colchicine; Colonic Neoplasms; Dose-Response Relationship, Drug; Flavonoids; Hydroxyindoleacetic Acid; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Serotonin; Time Factors; Vinblastine; Xanthenes; Xanthones

1997
Measurement of plasma 5-hydroxyindoleacetic acid as a possible clinical surrogate marker for the action of antivascular agents.
    Clinica chimica acta; international journal of clinical chemistry, 2001, Volume: 314, Issue:1-2

    Topics: Angiogenesis Inhibitors; Biomarkers; Calibration; Chromatography, High Pressure Liquid; Clinical Trials, Phase I as Topic; Electrochemistry; Humans; Hydroxyindoleacetic Acid; Neoplasms; Quality Control; Reference Standards; Regional Blood Flow; Reproducibility of Results; Solutions; Xanthenes; Xanthones

2001
Oral activity and pharmacokinetics of 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in mice.
    Cancer chemotherapy and pharmacology, 2002, Volume: 49, Issue:1

    Topics: Administration, Oral; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Colonic Neoplasms; Female; Half-Life; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Nitric Oxide; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones

2002
DMXAA: an antivascular agent with multiple host responses.
    International journal of radiation oncology, biology, physics, 2002, Dec-01, Volume: 54, Issue:5

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Hydroxyindoleacetic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Models, Chemical; Necrosis; Neoplasm Transplantation; Neovascularization, Pathologic; Nitric Oxide; Receptors, Tumor Necrosis Factor; Serotonin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones

2002
Tumor interstitial fluid promotes malignant phenotypes of lung cancer independently of angiogenesis.
    Cancer prevention research (Philadelphia, Pa.), 2015, Volume: 8, Issue:11

    Topics: Animals; Apoptosis; Aquaporin 1; Autophagy; Carcinoma, Lewis Lung; Cell Movement; Cell Proliferation; Disease Progression; Epithelial-Mesenchymal Transition; Extracellular Fluid; Female; Humans; Hydroxyindoleacetic Acid; Inflammation; Lung Neoplasms; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplastic Stem Cells; Neovascularization, Pathologic; Phenotype; Platelet Endothelial Cell Adhesion Molecule-1; Wound Healing; Xanthones

2015