hydroxyindoleacetic acid has been researched along with selegiline in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (36.11) | 18.7374 |
| 1990's | 17 (47.22) | 18.2507 |
| 2000's | 6 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rinne, UK; Siirtola, T; Sonninen, V | 1 |
| Kaakkola, S; Wurtman, RJ | 1 |
| Kuhn, W; Przuntek, H | 1 |
| Chan, WW; Rausch, WD; Riederer, P; Schallauer, E; Weiser, M | 1 |
| Blandini, F; Bono, G; Martignoni, E; Merlo, P; Nappi, G; Sinforiani, E | 1 |
| Boulton, AA; Greenshaw, AJ; Juorio, AV | 1 |
| Bradbury, AJ; Costall, B; Jenner, PG; Kelly, ME; Marsden, CD; Naylor, RJ | 1 |
| Riederer, P; Youdim, MB | 1 |
| Arai, Y; Kinemuchi, H; Kisara, K; Matsumura, T; Sakuma, I; Satoh, N; Tadano, T | 1 |
| Cohen, RM; Mellow, AM; Mueller, EA; Murphy, DL; Newhouse, PA; Sunderland, T; Tariot, PN | 1 |
| Marsden, CA; Martin, KF; Palfreyman, MG; Sleight, AJ | 1 |
| McCauley, R; McIntyre, I; Oxenkrug, G; Yuwiler, A | 1 |
| Amedro, JB; Azzaro, AJ; Brown, LM; Smith, DJ; Williams, GM | 1 |
| Kaarttinen, A; Kallio, J; Koulu, M; Pyykkö, K; Scheinin, M; Vuorinen, J; Zimmer, RH | 1 |
| Kraus, P; Kuhn, W; Przuntek, H | 1 |
| Filipowicz, C; McCauley, R; McIntyre, IM; Oxenkrug, GF | 1 |
| Calne, DB; Ebert, MH; Eisler, T; Kopin, IJ; Krebs, H; Lake, CR; Murphy, DL; Nelson, R; Teräväinen, H; Weise, V; Whetzel, N | 1 |
| Artigas, F; Celada, P | 2 |
| Holdup, D; Liptrot, J; Phillipson, O | 1 |
| Cohen, RM; Lawlor, BA; Mellow, AM; Molchan, S; Mueller, EA; Murphy, DL; Newhouse, PA; Sunderland, T; Tariot, PN | 1 |
| Nichols, DE; Sprague, JE | 2 |
| Gupta, M; Wiener, HL | 1 |
| Sivam, SP | 1 |
| Boulton, AA; Davis, BA; Durden, DA; Ivy, G; Juorio, AV; Mendonca, A; Milgram, W; Paterson, IA; Wu, P; Yu, PH | 1 |
| Dingemanse, J; Kettler, R; Kneer, J; Korn, A; Koulu, M; Wallnöfer, A; Zürcher, G | 1 |
| Johnson, MP; Nichols, DE; Schmidt, CJ; Sprague, JE | 1 |
| Anttila, M; Heinonen, E; Helminen, A; Huupponen, R; Laine, K; Mäki-Ikola, O; Reinikainen, K; Scheinin, M | 1 |
| Quadri, SK; ThyagaRajan, S | 1 |
| Andrzejewski, W; Fogel, WA; Maslinski, C; Sasiak, K | 1 |
| Felten, DL; Madden, KS; Stevens, SY; ThyagaRajan, S | 1 |
| MohanKumar, PS; MohanKumar, SM; Quadri, SK | 1 |
| Fisher, H; Halladay, AK; Hesse, K; Kirschner, E; Wagner, GC | 1 |
| Brewer, F; Clarke, A; Corn, TH; Hartig, F; Johnson, ES; Mallard, N; Taylor, S | 1 |
| Dalal, A; Poddar, MK | 1 |
7 trial(s) available for hydroxyindoleacetic acid and selegiline
| Article | Year |
|---|---|
Monoamines and related metabolite levels in the cerebrospinal fluid of patients with dementia of Alzheimer type. Influence of treatment with L-deprenyl.
Topics: Aged; Alzheimer Disease; Biogenic Monoamines; Cognition; Dopamine; Double-Blind Method; Epinephrine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Middle Aged; Neuropsychological Tests; Norepinephrine; Psychiatric Status Rating Scales; Psychological Tests; Selegiline | 1991 |
Inhibition of monoamine oxidase by moclobemide: effects on monoamine metabolism and secretion of anterior pituitary hormones and cortisol in healthy volunteers.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Benzamides; Blood Platelets; Catecholamines; Dose-Response Relationship, Drug; Double-Blind Method; Epinephrine; Homovanillic Acid; Humans; Hydrocortisone; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Norepinephrine; Pituitary Hormones, Anterior; Random Allocation; Selegiline; Vanilmandelic Acid | 1989 |
Deprenyl in Parkinson disease.
Topics: Adult; Aged; Carbidopa; Dopamine; Double-Blind Method; Drug Combinations; Epinephrine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Methoxyhydroxyphenylglycol; Middle Aged; Parkinson Disease; Phenethylamines; Selegiline | 1981 |
High-dose selegiline in treatment-resistant older depressive patients.
Topics: Age Factors; Aged; Blood Pressure; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hydroxyindoleacetic Acid; Hypotension, Orthostatic; Male; Methoxyhydroxyphenylglycol; Middle Aged; Placebos; Psychiatric Status Rating Scales; Selegiline; Treatment Outcome | 1994 |
Pharmacokinetic-pharmacodynamic interactions between two selective monoamine oxidase inhibitors: moclobemide and selegiline.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Benzamides; Blood Platelets; Double-Blind Method; Drug Interactions; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Moclobemide; Monoamine Oxidase Inhibitors; Neurotransmitter Agents; Selegiline | 1996 |
Lack of adverse interactions between concomitantly administered selegiline and citalopram.
Topics: Adult; Antidepressive Agents; Citalopram; Double-Blind Method; Drug Administration Schedule; Drug Interactions; Epinephrine; Humans; Hydroxyindoleacetic Acid; Male; Monoamine Oxidase Inhibitors; Naphthols; Norepinephrine; Placebos; Prolactin; Propylene Glycols; Selective Serotonin Reuptake Inhibitors; Selegiline; Serotonin | 1997 |
A new formulation of selegiline: improved bioavailability and selectivity for MAO-B inhibition.
Topics: Administration, Oral; Adult; Aged; Amphetamine; Biological Availability; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Female; Humans; Hydroxyindoleacetic Acid; Male; Metabolic Clearance Rate; Methamphetamine; Middle Aged; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Phenethylamines; Selegiline | 2003 |
29 other study(ies) available for hydroxyindoleacetic acid and selegiline
| Article | Year |
|---|---|
L-deprenyl treatment of on-off phenomena in Parkinson's disease.
Topics: Aged; Benserazide; Dopamine; Drug Therapy, Combination; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Phenethylamines; Selegiline; Vanilmandelic Acid | 1978 |
Effects of COMT inhibitors on striatal dopamine metabolism: a microdialysis study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzophenones; Catechol O-Methyltransferase Inhibitors; Catechols; Chromatography, High Pressure Liquid; Clorgyline; Corpus Striatum; Dialysis; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Nitriles; Nitrophenols; Nomifensine; Rats; Rats, Inbred Strains; Selegiline; Tolcapone | 1992 |
The effect of R-(-)-deprenyl in de novo parkinsonian patients pretreated with levodopa and decarboxylase inhibitor correlated to depression and MHPS, HIAA, and HVA levels of cerebrospinal fluid.
Topics: Carboxy-Lyases; Depressive Disorder; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Male; Methoxyhydroxyphenylglycol; Middle Aged; Motor Skills; Neurologic Examination; Parkinson Disease; Selegiline | 1990 |
Effects of L-deprenyl and amantadine in an MPTP-model of parkinsonism.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Amantadine; Animals; Caudate Nucleus; Corpus Striatum; Dopamine; Drug Interactions; Female; Gerbillinae; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Parkinson Disease, Secondary; Selegiline; Serotonin | 1990 |
Behavioral and neurochemical effects of deprenyl and beta-phenylethylamine in Wistar rats.
Topics: Animals; Brain Chemistry; Brain Stem; Corpus Striatum; Homovanillic Acid; Hydroxyindoleacetic Acid; Hypothalamus; Male; Phenethylamines; Rats; Rats, Inbred Strains; Selegiline; Self Stimulation | 1985 |
The neurotoxic actions of 1-methyl-4-phenylpyridine (MPP+) are not prevented by deprenyl treatment.
Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Limbic System; Mice; Motor Activity; Neurotransmitter Agents; Norepinephrine; Parkinson Disease, Secondary; Phenethylamines; Pyridinium Compounds; Selegiline; Serotonin | 1985 |
Monoamine oxidase activity and monoamine metabolism in brains of parkinsonian patients treated with l-deprenyl.
Topics: Aged; Amines; Brain; Dopamine; Female; Humans; Hydroxyindoleacetic Acid; Indans; Kynuramine; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Parkinson Disease; Phenethylamines; Selegiline; Serotonin; Tissue Distribution; Tranylcypromine | 1986 |
Behavioral and biochemical changes following acute administration of MPTP and MPP+.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Desipramine; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Motor Activity; Nomifensine; Pyridines; Pyridinium Compounds; Selegiline; Serotonin | 1987 |
Dose-dependent effects of deprenyl on CSF monoamine metabolites in patients with Alzheimer's disease.
Topics: Aging; Alzheimer Disease; Biogenic Amines; Dose-Response Relationship, Drug; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methoxyhydroxyphenylglycol; Middle Aged; Phenethylamines; Selegiline | 1987 |
Relationship between extracellular 5-hydroxytryptamine and behaviour following monoamine oxidase inhibition and L-tryptophan.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Clorgyline; Hydroxyindoleacetic Acid; Indoles; Male; Monoamine Oxidase Inhibitors; Rats; Rats, Inbred Strains; Selegiline; Serotonin; Time Factors; Tranylcypromine; Tryptophan; Tyrosine | 1988 |
Effect of selective monoamine oxidase inhibitors on rat pineal melatonin synthesis in vitro.
Topics: Animals; Arylamine N-Acetyltransferase; Clorgyline; Hydroxyindoleacetic Acid; Hydroxytryptophol; Melatonin; Monoamine Oxidase; Norepinephrine; Organ Culture Techniques; Phenethylamines; Pineal Gland; Propranolol; Propylamines; Rats; Rats, Inbred F344; Rats, Inbred Strains; Selegiline; Serotonin; Tryptophan | 1988 |
The effect of selective type A or type B monoamine oxidase inhibition on the intrasynaptosomal deamination of (3H)serotonin in rat spinal cord tissue.
Topics: Animals; Clorgyline; Cytoplasm; Deamination; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Monoamine Oxidase Inhibitors; Rats; Rats, Inbred Strains; Selegiline; Serotonin; Spinal Cord; Synaptosomes | 1988 |
The effect of R-(-)-deprenyl in de novo parkinsonian patients pretreated with levodopa and decarboxylase inhibitor correlated to depression and MHPG, HIAA and HVA levels in the cerebrospinal fluid.
Topics: Benserazide; Depression; Double-Blind Method; Drug Therapy, Combination; Female; Glycols; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Levodopa; Male; Methoxyhydroxyphenylglycol; Middle Aged; Motor Activity; Parkinson Disease; Phenethylamines; Selegiline | 1989 |
Selective inhibition of MAO-A but not MAO-B activity increases rat pineal melatonin.
Topics: Animals; Clorgyline; Hydroxyindoleacetic Acid; Isoenzymes; Male; Melatonin; Phenethylamines; Pineal Gland; Propylamines; Rats; Rats, Inbred Strains; Selegiline; Serotonin | 1985 |
Plasma 5-hydroxyindoleacetic acid as an indicator of monoamine oxidase-A inhibition in rat brain and peripheral tissues.
Topics: Animals; Biomarkers; Brain; Chromatography, High Pressure Liquid; Clorgyline; Hydroxyindoleacetic Acid; Isoenzymes; Kinetics; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Rats; Rats, Wistar; Selegiline; Serotonin; Tranylcypromine | 1993 |
1,2,3,4-Tetrahydro-2-methyl-4,6,7-isoquinolinetriol depletes catecholamines in rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Cerebral Ventricles; Clorgyline; Corpus Striatum; Dopamine; Functional Laterality; Homovanillic Acid; Hydroxyindoleacetic Acid; Hypothalamus; Infusions, Parenteral; Isoquinolines; Locus Coeruleus; Male; Microinjections; Norepinephrine; Organ Specificity; Raphe Nuclei; Rats; Rats, Wistar; Selegiline; Serotonin; Stereotaxic Techniques; Substantia Nigra; Thalamus | 1993 |
The monoamine oxidase-B inhibitor L-deprenyl protects against 3,4-methylenedioxymethamphetamine-induced lipid peroxidation and long-term serotonergic deficits.
Topics: Animals; Brain; Hydroxyindoleacetic Acid; Lipid Peroxidation; Male; Monoamine Oxidase Inhibitors; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Selegiline; Serotonin; Synaptosomes; Tryptophan Hydroxylase | 1995 |
Inhibition of MAO-B protects against MDMA-induced neurotoxicity in the striatum.
Topics: Animals; Corpus Striatum; Hydroxyindoleacetic Acid; Male; Monoamine Oxidase Inhibitors; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Rats; Rats, Sprague-Dawley; Selegiline; Serotonin; Sodium Chloride | 1995 |
Effects of deprenyl on monoamine oxidase and neurotransmitters in the brains of MPTP-treated aging mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Corpus Striatum; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase; Neurotransmitter Agents; Olfactory Pathways; Selegiline | 1995 |
Monoamine oxidase inhibitors increase preferentially extracellular 5-hydroxytryptamine in the midbrain raphe nuclei. A brain microdialysis study in the awake rat.
Topics: Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Clorgyline; Dialysis; Extracellular Space; Hydroxyindoleacetic Acid; Male; Monoamine Oxidase Inhibitors; Raphe Nuclei; Rats; Rats, Wistar; Selegiline; Serotonin; Tranylcypromine | 1993 |
Influence of monoamine oxidase inhibitors on striatonigral dynorphin system: a study with deprenyl and clorgyline.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Clorgyline; Corpus Striatum; Dopamine; Dynorphins; Hydroxyindoleacetic Acid; Male; Monoamine Oxidase Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Selegiline; Serotonin; Substantia Nigra | 1993 |
Inhibition of MAO-B by (-)-deprenyl alters dopamine metabolism in the macaque (Macaca facicularis) brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Caudate Nucleus; Dopamine; Frontal Lobe; Homovanillic Acid; Hydroxyindoleacetic Acid; Macaca fascicularis; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Phenethylamines; Selegiline; Serotonin | 1995 |
Studies on the mechanism of p-chloroamphetamine neurotoxicity.
Topics: Animals; Brain; Clorgyline; Dopamine; Fever; Hydroxyindoleacetic Acid; Indans; Male; Monoamine Oxidase Inhibitors; N-Methyl-3,4-methylenedioxyamphetamine; Neuroprotective Agents; Neurotoxins; p-Chloroamphetamine; Paroxetine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Selegiline; Serotonin; Serotonin Agents | 1996 |
L-deprenyl inhibits tumor growth, reduces serum prolactin, and suppresses brain monoamine metabolism in rats with carcinogen-induced mammary tumors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Body Weight; Brain; Dopamine; Eating; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Mammary Neoplasms, Experimental; Monoamine Oxidase Inhibitors; Norepinephrine; Prolactin; Rats; Rats, Sprague-Dawley; Selegiline | 1999 |
The effect of in vivo deprenyl on cerebral amine system in rats with portocaval shunts.
Topics: Animals; Biogenic Monoamines; Brain; Dopamine; Histamine; Hydroxyindoleacetic Acid; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Norepinephrine; Portacaval Shunt, Surgical; Rats; Selegiline; Serotonin | 2000 |
Anti-tumor effect of L-deprenyl is associated with enhanced central and peripheral neurotransmission and immune reactivity in rats with carcinogen-induced mammary tumors.
Topics: 3,4-Dihydroxyphenylacetic Acid; 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Female; Flow Cytometry; Hydroxyindoleacetic Acid; Immune System; Interferon-gamma; Interleukin-2; Killer Cells, Natural; Mammary Neoplasms, Experimental; Monoamine Oxidase Inhibitors; Neuroimmunomodulation; Norepinephrine; Rats; Rats, Sprague-Dawley; Selegiline; Serotonin; Spleen; Sympathetic Nervous System; Synaptic Transmission; T-Lymphocytes | 2000 |
Deprenyl stimulates the efflux of monoamines from the rat hypothalamus in vitro.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Dopamine; Dose-Response Relationship, Drug; Hydroxyindoleacetic Acid; Hypothalamus; Male; Monoamine Oxidase Inhibitors; Neurons; Norepinephrine; Rats; Rats, Sprague-Dawley; Selegiline; Serotonin | 2001 |
Role of monoamine oxidase inhibition and monoamine depletion in fenfluramine-induced neurotoxicity and serotonin release.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Clorgyline; Corpus Striatum; Dopamine; Drug Interactions; Fenclonine; Fenfluramine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Monoamine Oxidase Inhibitors; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Selegiline; Serotonin; Serotonin Antagonists; Tryptophan | 2001 |
Short-term erythrosine B-induced inhibition of the brain regional serotonergic activity suppresses motor activity (exploratory behavior) of young adult mammals.
Topics: Animals; Brain; Clorgyline; Dose-Response Relationship, Drug; Erythrosine; Exploratory Behavior; Food Coloring Agents; Hydroxyindoleacetic Acid; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Motor Activity; Rats; Receptors, Serotonin; Selegiline; Serotonin; Time Factors; Tissue Distribution | 2009 |