hydroxyindoleacetic acid and sapropterin

hydroxyindoleacetic acid has been researched along with sapropterin in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19908 (32.00)18.7374
1990's9 (36.00)18.2507
2000's7 (28.00)29.6817
2010's0 (0.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Blau, N; Cotton, RG; Heizmann, CW; Hoffmann, GF; Korenke, GC; Smooker, PM; Sperl, W1
Nakamura, S1
Anastasiadis, PZ; Arthur, RA; Kuhn, DM; Levine, RA; Wolf, WA; Ziaja, E1
Miyatake, T; Nakajima, T; Owada, M; Tanaka, K; Yoneda, M1
Curtius, HC; Niederwieser, A1
Hayaishi, O; Kagamiyama, H; Suzuki, S; Tsubokura, S; Watanabe, Y1
Burns, RS; Eldridge, R; Levine, RA; LeWitt, PA; Lovenberg, W; Miller, LP; Newman, RP; Papavasiliou, A; Rayes, A1
Dissing, IC; Gerdes, AM; Güttler, F; Lou, H; Lykkelund, C; Pakkenberg, H; Rasmussen, V1
Argoff, CE; Barton, NW; Brady, RO; Fink, JK; Hallett, M; Levine, RA; Ravin, P1
Knapp, S; Mandell, AJ; Russo, PV; Stewart, KD; Vitto, A1
Boespflug, O; Demeocq, F; Guyon, A; Malpuech, G; Piton, A; Vanlieferinghen, P1
Blau, N; Cabral, A; de Almeida, IT; Eusébio, F; Leandro, PP; Matasovic, A; Portela, R; Tasso, T1
Candito, M; Chambon, P; Chatel, M; Nagatsu, T1
Kato, H; Komori, H; Matsuishi, T; Ohtaki, E; Yamada, S; Yamashita, Y1
Bowron, A; Heales, SJ; Howells, DW; Hyland, K; Smith, I; Surtees, RA1
Lamers, KJ; Wevers, RA1
Arnold, LA; Blau, N; Hyland, K; Renneberg, A; Thöny, B1
Crawley, J; Dobbie, M; Marsh, K; Surtees, R; Waruiru, C1
Allen, RP; Earley, CJ; Hyland, K1
Cianchetti, C; di Porzio, U; Lilliu, V; Mancosu, C; Sorrentino, G; Zuddas, A1
Crawley, F; Heales, S; Rudge, P1
Hashimoto, T; Kagami, S; Kuroda, Y; Miyazaki, M; Mori, K; Nozaki, S; Toda, Y; Watanabe, Y1
Högl, B1
Ballhausen, D; Baumgartner, MR; Blau, N; Fiori, L; Giovannini, M; Hoffmann, GF; Ibel, H; Jäggi, L; Ponzone, A; Porta, F; Santer, R; Schuler, A; Wendel, U; Zurflüh, MR1
Anstey, NM; DeRisi, JL; Florence, SM; Granger, DL; Hyland, K; Langelier, C; Lopansri, BK; Mukemba, JP; Mwaikambo, ED; Nakielny, S; Rubach, MP; Simmons, RA; Weinberg, JB; Yeo, TW1

Reviews

2 review(s) available for hydroxyindoleacetic acid and sapropterin

ArticleYear
Senile dementia and presenile dementia.
    The Tohoku journal of experimental medicine, 1990, Volume: 161 Suppl

    Topics: Acetylcholinesterase; Alzheimer Disease; Arginine Vasopressin; Biopterins; Brain Chemistry; Cerebral Cortex; Choline O-Acetyltransferase; Cross-Sectional Studies; Dementia; Dopamine beta-Hydroxylase; Glutamate Decarboxylase; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Japan; Neurotransmitter Agents

1990
[Detection, differential diagnosis, and prenatal diagnosis of tetrahydrobiopterin deficiency].
    Archives francaises de pediatrie, 1987, Volume: 44 Suppl 1

    Topics: Alcohol Oxidoreductases; Amino Acid Metabolism, Inborn Errors; Biopterins; Diagnosis, Differential; Female; Guanosine Triphosphate; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Phenylalanine; Phosphorus-Oxygen Lyases; Pregnancy; Prenatal Diagnosis

1987

Trials

2 trial(s) available for hydroxyindoleacetic acid and sapropterin

ArticleYear
Tetrahydrobiopterin and Parkinson's disease.
    Acta neurologica Scandinavica, 1989, Volume: 79, Issue:6

    Topics: Adult; Antiparkinson Agents; Benserazide; Biopterins; Clinical Trials as Topic; Drug Combinations; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Male; Middle Aged; Parkinson Disease; Tyrosine

1989
Administration of secretin for autism alters dopamine metabolism in the central nervous system.
    Brain & development, 2006, Volume: 28, Issue:2

    Topics: Autistic Disorder; Biopterins; Central Nervous System; Child; Child, Preschool; Dopamine; Female; Homovanillic Acid; Hormones; Humans; Hydroxyindoleacetic Acid; Male; Psychiatric Status Rating Scales; Secretin; Time Factors

2006

Other Studies

21 other study(ies) available for hydroxyindoleacetic acid and sapropterin

ArticleYear
Atypical (mild) forms of dihydropteridine reductase deficiency: neurochemical evaluation and mutation detection.
    Pediatric research, 1992, Volume: 32, Issue:6

    Topics: Amino Acid Metabolism, Inborn Errors; Biopterins; Child, Preschool; Dihydropteridine Reductase; DNA Mutational Analysis; Erythrocytes; Female; Humans; Hydroxyindoleacetic Acid; Infant; Male; Phenylalanine; Phenylketonurias; Pterins; Skin

1992
Effect of tetrahydrobiopterin on serotonin synthesis, release, and metabolism in superfused hippocampal slices.
    Journal of neurochemistry, 1991, Volume: 57, Issue:4

    Topics: 5-Methoxytryptamine; Animals; Biopterins; Calcium; Hippocampus; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Osmolar Concentration; Perfusion; Potassium Chloride; Rats; Rats, Inbred Strains; Serotonin

1991
Dihydrobiopterin synthesis defect: an adult with diurnal fluctuation of symptoms.
    Neurology, 1987, Volume: 37, Issue:3

    Topics: Adult; Alcohol Oxidoreductases; Amino Acid Metabolism, Inborn Errors; Biopterins; Circadian Rhythm; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Neopterin; Phenylalanine

1987
Decrease in tetrahydrobiopterin content and neurotransmitter amine biosynthesis in rat brain by an inhibitor of guanosine triphosphate cyclohydrolase.
    Brain research, 1988, Apr-12, Volume: 446, Issue:1

    Topics: 5-Hydroxytryptophan; Adrenal Glands; Aminohydrolases; Animals; Biogenic Amines; Biopterins; Brain; Dihydroxyphenylalanine; Dopamine; GTP Cyclohydrolase; Hydrazines; Hydroxyindoleacetic Acid; Hypoxanthines; Liver; Male; Neurotransmitter Agents; Norepinephrine; Organ Specificity; Rats; Rats, Inbred Strains; Serotonin

1988
Pterin abnormalities in dystonia: a metabolic marker with therapeutic implications.
    Advances in neurology, 1988, Volume: 50

    Topics: Adult; Biopterins; Central Nervous System; Dystonia; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Middle Aged; Neopterin; Pterins

1988
Tetrahydrobiopterin administration in biopterin-deficient progressive dystonia with diurnal variation.
    Neurology, 1989, Volume: 39, Issue:10

    Topics: Adult; Biopterins; Child; Circadian Rhythm; Dystonia; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Locomotion; Male

1989
Strain differences in kinetic and thermal stability of two mouse brain tryptophan hydroxylase activities.
    Brain research, 1981, Dec-28, Volume: 230, Issue:1-2

    Topics: Animals; Biopterins; Brain; Hydroxyindoleacetic Acid; Kinetics; Male; Mice; Mice, Inbred Strains; Serotonin; Species Specificity; Temperature; Tryptophan; Tryptophan Hydroxylase

1981
[Malignant phenylketonuria caused by biopterin synthetase deficiency. Study of neuromediator catabolites in the cerebrospinal fluid during treatment].
    Archives francaises de pediatrie, 1984, Volume: 41, Issue:1

    Topics: Alcohol Oxidoreductases; Biopterins; Carbidopa; Follow-Up Studies; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Levodopa; Male; Neurotransmitter Agents; Phenylketonurias; Serotonin

1984
Tetrahydrobiopterin deficiency in Portugal: results of the screening for hyperphenylalaninemia.
    Advances in experimental medicine and biology, 1993, Volume: 338

    Topics: Adolescent; Biopterins; Child; Child, Preschool; Consanguinity; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant, Newborn; Male; Mass Screening; Metabolism, Inborn Errors; Phenylalanine; Phenylketonurias; Portugal; Pterins

1993
High-performance liquid chromatographic measurement of cerebrospinal fluid tetrahydrobiopterin, neopterin, homovanillic acid and 5-hydroxindoleacetic acid in neurological diseases.
    Journal of chromatography. B, Biomedical applications, 1994, Jul-01, Volume: 657, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Aged, 80 and over; Biopterins; Chromatography, High Pressure Liquid; Dopamine; Drug Stability; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Neopterin; Nervous System Diseases; Reproducibility of Results; Serotonin

1994
Cerebrospinal fluid biopterin and biogenic amine metabolites during oral R-THBP therapy for infantile autism.
    Journal of autism and developmental disorders, 1995, Volume: 25, Issue:2

    Topics: Autistic Disorder; Biopterins; Child; Child, Preschool; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Neurotransmitter Agents; Personality Assessment; Treatment Outcome

1995
Cerebrospinal fluid concentrations of pterins and metabolites of serotonin and dopamine in a pediatric reference population.
    Pediatric research, 1993, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Age Factors; Biopterins; Child; Child, Preschool; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Neopterin; Pterins; Reference Values; Serotonin

1993
Abnormalities of biogenic amines affecting the metabolism of serotonin and catecholamines.
    Multiple sclerosis (Houndmills, Basingstoke, England), 1998, Volume: 4, Issue:1

    Topics: Aromatic-L-Amino-Acid Decarboxylases; Biopterins; Catecholamines; Child; Child, Preschool; Dopa Decarboxylase; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Infant, Newborn; Metabolism, Inborn Errors; Methoxyhydroxyphenylglycol; Serotonin; Tyrosine 3-Monooxygenase

1998
Dihydropteridine reductase deficiency localized to the central nervous system.
    Journal of inherited metabolic disease, 1998, Volume: 21, Issue:4

    Topics: Biopterins; Central Nervous System; Child; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Phenylketonurias

1998
Cerebrospinal fluid studies in children with cerebral malaria: an excitotoxic mechanism?
    The American journal of tropical medicine and hygiene, 2000, Volume: 62, Issue:2

    Topics: Antimalarials; Biopterins; Brain; Child; Child, Preschool; Chromatography, High Pressure Liquid; Endothelium; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyindoleacetic Acid; Infant; Kenya; Malaria, Cerebral; Microglia; Neopterin; Nitrates; Nitrites; Quinolinic Acid; Tryptophan

2000
CSF dopamine, serotonin, and biopterin metabolites in patients with restless legs syndrome.
    Movement disorders : official journal of the Movement Disorder Society, 2001, Volume: 16, Issue:1

    Topics: Age Factors; Biopterins; Brain; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Neopterin; Restless Legs Syndrome; Serotonin; Spinal Cord

2001
6R-Tetrahydrobiopterin induces dopamine synthesis in a human neuroblastoma cell line, LA-N-1. A cellular model of DOPA-responsive dystonia.
    Brain research, 2002, Jul-12, Volume: 943, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Biopterins; Dopamine; Dopamine Antagonists; Dystonic Disorders; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Models, Biological; Monoamine Oxidase Inhibitors; Neuroblastoma; Neurons; Serotonin; Serotonin Antagonists; Substantia Nigra; Tryptophan Hydroxylase; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase

2002
Reversible parkinsonism following heroin pyrolysate inhalation is associated with tetrahydrobiopterin deficiency.
    Movement disorders : official journal of the Movement Disorder Society, 2004, Volume: 19, Issue:10

    Topics: Adult; Biopterins; Brain; Brain Diseases, Metabolic; Electroencephalography; Epilepsy; Female; Heroin; Heroin Dependence; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Magnetic Resonance Imaging; Parkinsonian Disorders

2004
Circadian rhythms in RLS.
    Sleep medicine, 2006, Volume: 7, Issue:3

    Topics: Biopterins; Chronobiology Disorders; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methyldopa; Nocturnal Myoclonus Syndrome; Restless Legs Syndrome

2006
Outcome and long-term follow-up of 36 patients with tetrahydrobiopterin deficiency.
    Molecular genetics and metabolism, 2008, Volume: 93, Issue:3

    Topics: Adolescent; Adult; Biopterins; Child; Dihydropteridine Reductase; Female; Follow-Up Studies; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant, Newborn; Male; Phenylketonurias; Phosphorus-Oxygen Lyases

2008
Cerebrospinal Fluid Pterins, Pterin-Dependent Neurotransmitters, and Mortality in Pediatric Cerebral Malaria.
    The Journal of infectious diseases, 2021, 10-28, Volume: 224, Issue:8

    Topics: Biopterins; Central Nervous System Diseases; Child; Child, Preschool; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Malaria, Cerebral; Male; Neopterin; Neurotransmitter Agents; Prospective Studies; Pterins; Reference Values; Tanzania; Tyrosine

2021