hydroxyindoleacetic acid has been researched along with p-chloroamphetamine in 89 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 45 (50.56) | 18.7374 |
| 1990's | 31 (34.83) | 18.2507 |
| 2000's | 12 (13.48) | 29.6817 |
| 2010's | 1 (1.12) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fuller, RW; Hemrick, SK; Perry, KW | 1 |
| Curzon, G; Fernando, JC; Marsden, CA | 1 |
| Boulanger, M; Duhault, J; Malen, C; Schmitt, H; Voisin, C | 1 |
| Massari, VJ; Sanders-Bush, E | 1 |
| Fuller, RW; Perry, KW | 2 |
| Fuller, RW; Gibson, WR; Meyers, DB; Snoddy, HD | 1 |
| Growdon, JH | 1 |
| Giambalvo, CT; Snodgrass, SR | 1 |
| Sanders-Bush, E; Steranka, LR | 1 |
| Charlton, KG; Shaw, G; Sugrue, MF | 1 |
| Ross, SB | 1 |
| Bushing, JA; Sanders-Bush, E; Sekerke, HJ; Smith, HE | 1 |
| Christensen, JA; Lassen, JB; Molander, L; Squires, RF | 1 |
| Fuller, RW; Gál, EM; Molloy, BB; Sherman, A | 1 |
| Baker, JC; Fuller, RW; Molloy, BB; Perry, KW | 1 |
| Leonard, BE | 1 |
| Bymaster, FP; Fuller, RW; Molloy, BB; Perry, KW; Roush, BW; Snoddy, HD; Wong, DT | 1 |
| Fuller, RW; Krushinski, JH; Robertson, DW; Snoddy, HD | 1 |
| Fuller, RW; Henderson, MG | 1 |
| Carli, M; Dewar, KM; Grondin, L; Lima, L; Reader, TA | 1 |
| Fuller, RW; Hemrick-Luecke, S; Henderson, MG | 1 |
| Artigas, F; Martín, F | 1 |
| Grahame-Smith, DG; Wang, H | 1 |
| Gołembiowska, K; Jaworska, L; Przegaliński, E | 1 |
| Goromaru, T; Hashimoto, K | 1 |
| Altman, HJ; Jenden, DJ; Kuhn, DM; Normile, HJ; Wolf, WA | 1 |
| Hughes, MG; Liu, D; McAdoo, DJ; Sorkin, LS; Willis, WD | 1 |
| Fattaccini, CM; Gozlan, H; Hamon, M | 1 |
| Freo, U; Larson, DM; Rapoport, SI; Soncrant, TT; Tolliver, T | 1 |
| Nurminen, ML; Paakkari, I; Seppälä, T | 1 |
| Hashimoto, K; Hayashi, M; Tanii, H | 1 |
| Bakhit, C; Gibb, JW; Peat, MA; Warren, PF | 1 |
| Fuller, RW; Hemrick-Luecke, SK; Robertson, DW | 1 |
| Chance, WT | 1 |
| Burke, DH; Ryan, RP | 1 |
| Fuller, RW; Perry, KW; Snoddy, HD | 1 |
| Broch, OJ; Fasmer, OB; Hole, K; Hunskaar, S | 1 |
| Axt, KJ; Commins, DL; Seiden, LS; Vosmer, G | 1 |
| Ishikawa, K; Kameyama, T; Nabeshima, T; Yamaguchi, K; Yoshida, S | 1 |
| Alesci, R; Bagnoli, P | 1 |
| Boon, P; Feenstra, MG; Heinsbroek, RP; Van de Poll, NE; Van Haaren, F | 1 |
| Curzon, G; Hutson, PH | 1 |
| Altman, HJ; Berman, RF; Normile, HJ; Ogren, SO | 1 |
| Alesci, R; Bagnoli, P; Porciatti, V; Sebastiani, L | 1 |
| Kuhn, DM; Wolf, WA; Youdim, MB | 1 |
| Fuller, RW; Molloy, BB | 1 |
| Fuller, RW; Snoddy, HD | 2 |
| Baldessarini, RJ; Gerson, SC | 1 |
| Fuller, RW; Kaiser, C | 1 |
| Marsden, CA; Singleton, C | 1 |
| Jacobs, W; Kissinger, PT; Malven, PV; Rasmussen, DD | 1 |
| Joseph, MH; Kennett, GA | 1 |
| Erdö, SL; Kiss, B; Rosdy, B | 1 |
| Chance, WT; Fischer, JE; von Meyenfeldt, M | 1 |
| Fuller, RW; Molloy, BB; Snoddy, HD | 1 |
| Hammond, DL; Tyce, GM; Yaksh, TL | 1 |
| Barden, N; Daigle, M; Di Paolo, T; Picard, V | 1 |
| Amano, M; Furukawa, H; Hiramatsu, M; Kameyama, T; Nabeshima, T; Yamaguchi, K | 1 |
| Alfaro, MJ; Colado, MI; Goicoechea, C; Lopez, F; Martin, MI; Ormazabal, MJ | 1 |
| Fuller, RW; Hemrick-Luecke, SK; Snoddy, HD | 1 |
| Cowen, PJ; Series, HG; Sharp, T | 1 |
| Besson, JM; Cespuglio, R; Jouvet, M; Puig, S; Rivot, JP | 1 |
| Colado, MI; Green, AR; Murray, TK | 1 |
| Adell, A; Artigas, F; Carceller, A | 1 |
| Altar, CA; Blue, ME; Mamounas, LA; Siuciak, JA | 1 |
| Hashimoto, K; Iyo, M; Minabe, Y; Narita, N; Yamazaki, K | 2 |
| Curzon, G; Datla, KP | 1 |
| Haroutunian, V; Knott, PJ; Santucci, AC | 1 |
| Johnson, MP; Nichols, DE; Schmidt, CJ; Sprague, JE | 1 |
| Battaglia, G; Cabrera-Vera, TM; Garcia, F; Pinto, W | 2 |
| Colado, MI; Green, AR; Misra, A; Murray, TK; Williams, JL | 1 |
| Altar, CA; Fritsche, M; Lindsay, RM | 1 |
| Apelqvist, G; Bengtsson, F; Bergqvist, PB; Hjorth, S; Wikell, C | 1 |
| Koivisto, E; MacDonald, E; Miettinen, R; Ruotsalainen, S; Sirviö, J | 1 |
| Altamura, C; Calia, E; Keller, F; Lucchese, F; Persico, AM; Puglisi-Allegra, S; Ventura, R | 1 |
| Basura, GJ; Walker, PD | 1 |
| Champney, TH; Chen, WJ; Manzana, EJ | 1 |
| Eller, M; Harro, J | 1 |
| Baumann, MH; Cadet, JL; Dersch, CM; Jayanthi, S; Prisinzano, T; Rice, KC; Rothman, RB; Wang, X | 1 |
| Eller, M; Häidkind, R; Harro, J; Harro, M; Kask, A; Oreland, L; Rinken, A | 1 |
| Aragón, MA; Avilés, A; Ayala, ME; Damián-Matsumura, P; Domínguez, R; Marín, M | 1 |
| Aznar, S; Knudsen, GM; Kornum, BR; Licht, CL; Weikop, P | 1 |
| Fukui, K; Kinoshita, S; Masaki, D; Nakatomi, Y; Tsuchida, H; Yokoyama, C; Yoshimoto, K | 1 |
| Eller, M; Häidkind, R; Harro, J; Kõiv, K; Mällo, T; Tõnissaar, M | 1 |
| Andrade, OG; Crispín, RH; Escobar, ME; Martínez, AA; Melández, JH; Méndez Palacios, N; Mendoza, MM | 1 |
3 review(s) available for hydroxyindoleacetic acid and p-chloroamphetamine
| Article | Year |
|---|---|
Actions of drugs that deplete serotonin.
Topics: 5,6-Dihydroxytryptamine; Amphetamines; Animals; Biological Transport; Brain; Fenclonine; Hydroxyindoleacetic Acid; p-Chloroamphetamine; Reserpine; Serotonin; Structure-Activity Relationship; Tryptamines; Tryptophan Hydroxylase | 1977 |
The role of brain and spinal cord norepinephrine in autoanalgesia.
Topics: Adrenergic alpha-Antagonists; Analgesia; Animals; Brain; Clonidine; Conditioning, Classical; Dose-Response Relationship, Drug; Drug Tolerance; Electroshock; Fear; Hydroxyindoleacetic Acid; Male; Methysergide; Nociceptors; Norepinephrine; p-Chloroamphetamine; Phenoxybenzamine; Phentolamine; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Spinal Cord; Time Factors; Tryptophan; Yohimbine | 1986 |
Motor effects of serotonin in the central nervous system.
Topics: 5-Hydroxytryptophan; 5,6-Dihydroxytryptamine; 5,7-Dihydroxytryptamine; Amphetamine; Animals; Brain; Fenclonine; Guinea Pigs; Hydroxyindoleacetic Acid; Monoamine Oxidase Inhibitors; Motor Activity; p-Chloroamphetamine; Raphe Nuclei; Rats; Serotonin; Serotonin Antagonists | 1980 |
86 other study(ies) available for hydroxyindoleacetic acid and p-chloroamphetamine
| Article | Year |
|---|---|
Modification by harmaline of the effects of N-cyclopropyl-p-chloro-amphetamine on 5-hydroxyindole concentration in rat brain.
Topics: Alkaloids; Amphetamines; Animals; Brain; Brain Chemistry; Harmaline; Hydroxyindoleacetic Acid; Indoles; Male; Monoamine Oxidase; p-Chloroamphetamine; Rats; Serotonin | 1979 |
5-Hydroxytryptamine: the effects of impaired synthesis on its metabolism and release in rat.
Topics: Animals; Brain; Brain Chemistry; Electric Stimulation; Fenclonine; Histamine Release; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Motor Activity; p-Chloroamphetamine; Rats; Serotonin; Synaptosomes; Tryptophan | 1978 |
Fenfluramine and 5-hydroxytryptamine. Part 2: Involvement of brain 5-hydroxytryptamine in the anorectic activity of fenfluramine.
Topics: Amides; Animals; Appetite Depressants; Brain; Brain Chemistry; Clomipramine; Fenclonine; Fenfluramine; Hydroxyindoleacetic Acid; Male; Norfenfluramine; p-Chloroamphetamine; Rats; Serotonin; Telencephalon; Time Factors; Tyramine | 1975 |
Inability of an inhibitor of amine uptake (Lilly 110140) to block depletion of brain 5-hydroxytrptamine by L-dopa.
Topics: Amines; Amphetamines; Animals; Brain Chemistry; Hydroxyindoleacetic Acid; Levodopa; Male; Mice; p-Chloroamphetamine; Propylamines; Rats; Serotonin | 1975 |
Depletion of brain serotonin by chronic administration of p-chloramphetamine orally to rats and dogs.
Topics: Amphetamines; Animals; Body Weight; Brain; Dogs; Female; Hydroxyindoleacetic Acid; Male; p-Chloroamphetamine; Rats; Serotonin; Species Specificity | 1979 |
Postural changes, tremor, and myoclonus in the rat immediately following injections of p-chloromaphetamine.
Topics: Amphetamines; Animals; Dose-Response Relationship, Drug; Hydroxyindoleacetic Acid; Male; Motor Activity; Myoclonus; p-Chloroamphetamine; Posture; Rats; Serotonin; Serotonin Antagonists; Tremor | 1977 |
Effect of p-chloroamphetamine and 5,7-dihydroxytryptamine on rotation and dopamine turnover.
Topics: 5,7-Dihydroxytryptamine; Amphetamine; Amphetamines; Animals; Apomorphine; Behavior; Cerebral Cortex; Corpus Striatum; Dihydroxytryptamines; Dominance, Cerebral; Dopamine; Humans; Hydroxyindoleacetic Acid; Male; Neural Pathways; Norepinephrine; p-Chloroamphetamine; Raphe Nuclei; Rats; Serotonin; Stereotyped Behavior; Substantia Nigra | 1978 |
Long-term effects of continuous exposure to p-chloroamphetamine on central serotonergic mechanisms in mice.
Topics: Amphetamines; Animals; Brain; Half-Life; Hydroxyindoleacetic Acid; Male; Mice; Neurons; p-Chloroamphetamine; Serotonin; Synaptosomes; Time Factors; Tryptophan Hydroxylase | 1978 |
Some effects of mazindol, an anorectic drug, on rat brain monoaminergic systems.
Topics: Animals; Biogenic Amines; Brain; Brain Chemistry; Corpus Striatum; Dopamine; Drug Interactions; Hydroxydopamines; Hydroxyindoleacetic Acid; Indoles; Male; Mazindol; Norepinephrine; p-Chloroamphetamine; p-Hydroxyamphetamine; Rats; Serotonin; Tryptophan | 1977 |
Antagonism of the acute and long-term biochemical effects of 4-chloroamphetamine on the 5-HT neurones in the rat brain by inhibitors of the 5-hydroxytryptamine uptake.
Topics: Allylamine; Amphetamines; Animals; Brain; Clomipramine; Dibenzazepines; Drug Interactions; Hydroxyindoleacetic Acid; Male; Monoamine Oxidase; Neurons; Norepinephrine; p-Chloroamphetamine; Proadifen; Pyridines; Rats; Serotonin; Synaptosomes; Time Factors | 1976 |
Correlation between brain levels and biochemical effects of the optical isomers of p-chloroamphetamine.
Topics: Amphetamines; Animals; Brain; Brain Chemistry; Hydroxyindoleacetic Acid; Male; p-Chloroamphetamine; Rats; Serotonin; Stereoisomerism; Synaptosomes; Time Factors; Tryptophan Hydroxylase | 1975 |
Neurochemical and pharmacological studies on a new 5HT-uptake inhibitor, FG4963, with potential antidepressant properties.
Topics: Animals; Anisoles; Anticonvulsants; Antidepressive Agents, Tricyclic; Autonomic Nervous System; Brain; Hydroxyindoleacetic Acid; Iris; Mice; Motor Activity; Norepinephrine; p-Chloroamphetamine; Piperidines; Rats; Serotonin; Serotonin Antagonists; Synaptosomes; Tyramine | 1975 |
Effects of intraventricular p-chloroamphetamine and its analogues on cerebral 5-HT.
Topics: Amphetamines; Animals; Brain; Brain Chemistry; Dose-Response Relationship, Drug; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Injections, Intraventricular; p-Chloroamphetamine; Rats; Serotonin; Structure-Activity Relationship; Time Factors | 1975 |
Comparison of 4-chloro-, 4-bromo- and 4-fluoroamphetamine in rats: drug levels in brain and effects on brain serotonin metabolism.
Topics: Amphetamines; Animals; Brain; Brain Chemistry; Hydroxyindoleacetic Acid; Male; Monoamine Oxidase; p-Chloroamphetamine; Rats; Serotonin; Time Factors; Tryptophan Hydroxylase | 1975 |
Acute and chronic effects of 4-chloroamphetamine on monoamine metabolism in the rat brain.
Topics: Amphetamines; Animals; Biogenic Amines; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Hydroxyindoleacetic Acid; Male; Norepinephrine; Normetanephrine; p-Chloroamphetamine; Rats; Serotonin; Time Factors; Tryptophan; Tyramine; Tyrosine | 1976 |
Inability of methadone to prevent the depletion of brain 5-hydroxyindoles by p-chloroamphetamine.
Topics: Amphetamines; Animals; Brain; Depression, Chemical; Hydroxyindoleacetic Acid; Indoles; Male; Methadone; Mice; p-Chloroamphetamine; Probenecid; Rats | 1976 |
The effects of quipazine on serotonin metabolism in rat brain.
Topics: Amides; Animals; Biological Transport; Brain; Hydroxyindoleacetic Acid; Male; Monoamine Oxidase Inhibitors; p-Chloroamphetamine; Piperazines; Quinolines; Rats; Receptors, Drug; Serotonin; Time Factors | 1976 |
Comparison of norfluoxetine enantiomers as serotonin uptake inhibitors in vivo.
Topics: Animals; Dose-Response Relationship, Drug; Fluoxetine; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred ICR; p-Chloroamphetamine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Stereoisomerism | 1992 |
Dextromethorphan antagonizes the acute depletion of brain serotonin by p-chloroamphetamine and H75/12 in rats.
Topics: Amphetamines; Animals; Brain; Dextromethorphan; Hydroxyindoleacetic Acid; Male; p-Chloroamphetamine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin | 1992 |
[3H]paroxetine binding and serotonin content of rat cortical areas, hippocampus, neostriatum, ventral mesencephalic tegmentum, and midbrain raphe nuclei region following p-chlorophenylalanine and p-chloroamphetamine treatment.
Topics: Animals; Brain; Fenclonine; Hydroxyindoleacetic Acid; Male; p-Chloroamphetamine; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Tissue Distribution; Tritium | 1992 |
MK-801 protects against amphetamine-induced striatal dopamine depletion in iprindole-treated rats, but not against brain serotonin depletion after p-chloroamphetamine administration.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Brain; Corpus Striatum; Dizocilpine Maleate; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Iprindole; Mice; p-Chloroamphetamine; Rats; Serotonin | 1992 |
Simultaneous effects of p-chloroamphetamine, d-fenfluramine, and reserpine on free and stored 5-hydroxytryptamine in brain and blood.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Fenfluramine; Hydroxyindoleacetic Acid; Male; Osmolar Concentration; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Reserpine; Serotonin | 1992 |
The effects of rubidium, caesium and quinine on 5-HT-mediated behaviour in rat and mouse--1. Rubidium.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Body Temperature; Brain; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; p-Chloroamphetamine; Potassium Channels; Rats; Rats, Inbred Strains; Rubidium; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes; Tranylcypromine | 1992 |
The effect of p-chloroamphetamine and p-chlorophenylalanine on the level of thyrotropin-releasing hormone and its receptors in some brain structures and lumbar spinal cord of the rat.
Topics: Animals; Brain; Citalopram; Corpus Striatum; Fenclonine; Hydroxyindoleacetic Acid; Male; Nucleus Accumbens; p-Chloroamphetamine; Rats; Rats, Wistar; Receptors, Neurotransmitter; Receptors, Thyrotropin-Releasing Hormone; Serotonin; Spinal Cord; Thyrotropin-Releasing Hormone | 1992 |
High-affinity [3H]6-nitroquipazine binding sites in rat brain.
Topics: Animals; Binding Sites; Binding, Competitive; Brain Chemistry; Hydroxyindoleacetic Acid; In Vitro Techniques; Kinetics; Male; Membranes; Nerve Endings; p-Chloroamphetamine; Quinolines; Quipazine; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists | 1990 |
Effects of combined serotonin depletion and lesions of the nucleus basalis magnocellularis on acquisition of a complex spatial discrimination task in the rat.
Topics: Analysis of Variance; Animals; Biogenic Amines; Choline O-Acetyltransferase; Discrimination Learning; Hydroxyindoleacetic Acid; Ibotenic Acid; Male; p-Chloroamphetamine; Radioligand Assay; Rats; Rats, Inbred Strains; Serotonin; Spatial Behavior; Substantia Innominata | 1990 |
Release and metabolism of 5-hydroxytryptamine in the cat spinal cord examined with microdialysis.
Topics: Aconitine; Animals; Cats; Dialysis; Female; Fluoxetine; Hydroxyindoleacetic Acid; Male; Monoamine Oxidase Inhibitors; p-Chloroamphetamine; Potassium; Serotonin; Spinal Cord; Tetrodotoxin; Veratridine | 1991 |
Differential effects of d-fenfluramine and p-chloroamphetamine on H75/12-induced depletion of 5-hydroxytryptamine and dopamine in the rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamines; Animals; Brain; Brain Stem; Cerebral Cortex; Corpus Striatum; Dopamine; Fenfluramine; Hippocampus; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Monoamine Oxidase Inhibitors; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Reference Values; Serotonin | 1991 |
Parachloroamphetamine selectively alters regional cerebral metabolic responses to the serotonergic agonist metachlorophenylpiperazine in rats.
Topics: Animals; Arecoline; Biogenic Amines; Brain; Bromocriptine; Deoxyglucose; Hydroxyindoleacetic Acid; Kinetics; Male; Organ Specificity; p-Chloroamphetamine; Piperazines; Quipazine; Rats; Rats, Inbred F344; Serotonin | 1991 |
Serotonergic involvement in the cardiovascular stimulation by thyrotropin-releasing hormone (TRH) in anesthetized rats.
Topics: Animals; Blood Pressure; Brain; Cardiovascular System; Fenclonine; Heart Rate; Hydroxyindoleacetic Acid; Male; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Serotonin; Thyrotropin-Releasing Hormone | 1991 |
Behavioral syndrome induced by allylnitrile, crotononitrile or 2-pentenenitrile in rats.
Topics: Animals; Behavior, Animal; Brain; Cyproheptadine; Fenclonine; Hydroxyindoleacetic Acid; Male; Methysergide; Movement Disorders; Nitriles; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin | 1991 |
The acute effects of methamphetamine, amphetamine and p-chloroamphetamine on the cortical serotonergic system of the rat brain: evidence for differences in the effects of methamphetamine and amphetamine.
Topics: Amphetamine; Amphetamines; Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Hydroxyindoleacetic Acid; Male; Methamphetamine; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Serotonin; Time Factors; Tryptophan Hydroxylase | 1985 |
Comparison of 1-methyl-4-(p-chlorophenyl)-1,2,3,6-tetrahydropyridine, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and p-chloroamphetamine as monoamine depletors.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Amphetamines; Animals; Biogenic Amines; Brain Chemistry; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; p-Chloroamphetamine; Pyridines; Rats; Rats, Inbred Strains; Serotonin; Time Factors | 1985 |
Cyproheptadine antagonism of p-chloroamphetamine hypothermia in mice.
Topics: Amphetamines; Animals; Body Temperature Regulation; Brain Chemistry; Cyproheptadine; Fluoxetine; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred ICR; p-Chloroamphetamine; Serotonin | 1986 |
p-Chloroamphetamine formation responsible for long-term depletion of brain serotonin after N-cyclopropyl-p-chloroamphetamine injection in rats.
Topics: Amphetamines; Animals; Brain; Hydroxyindoleacetic Acid; Male; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Serotonin; Time Factors | 1987 |
Involvement of central serotonergic pathways in nefopam-induced antinociception.
Topics: Analgesics; Animals; Behavior, Animal; Brain Chemistry; Cerebral Cortex; Fenclonine; Hydroxyindoleacetic Acid; Male; Mice; Nefopam; Neural Pathways; Oxazocines; p-Chloroamphetamine; Reaction Time; Serotonin; Spinal Cord | 1987 |
Endogenously produced 5,6-dihydroxytryptamine may mediate the neurotoxic effects of para-chloroamphetamine.
Topics: 5,6-Dihydroxytryptamine; Amphetamines; Animals; Brain Chemistry; Hippocampus; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Male; Nerve Degeneration; Neurotoxins; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Serotonin; Somatosensory Cortex | 1987 |
Phencyclidine-induced head-weaving and head-twitch through interaction with 5-HT1 and 5-HT2 receptors in reserpinized rats.
Topics: Animals; Brain; Hydroxyindoleacetic Acid; Imipramine; In Vitro Techniques; Male; Methoxydimethyltryptamines; p-Chloroamphetamine; Phencyclidine; Pindolol; Piperidines; Rats; Rats, Inbred F344; Receptors, Serotonin; Reserpine; Ritanserin; Serotonin; Serotonin Antagonists; Stereotyped Behavior | 1987 |
Endogenous levels of serotonin and 5-hydroxyindoleacetic acid in specific areas of the pigeon CNS: effects of serotonin neurotoxins.
Topics: 5,7-Dihydroxytryptamine; Amphetamines; Animals; Central Nervous System; Columbidae; Dihydroxytryptamines; Female; Hydroxyindoleacetic Acid; Male; Neurotoxins; Optic Lobe, Nonmammalian; p-Chloroamphetamine; Retina; Serotonin | 1988 |
Sex differences in passive avoidance depend on the integrity of the central serotonergic system.
Topics: Animals; Behavior, Animal; Dopamine; Female; Frontal Lobe; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Serotonin; Sex Characteristics | 1988 |
Concurrent determination of effects of p-chloroamphetamine on central extracellular 5-hydroxytryptamine concentration and behaviour.
Topics: Amphetamines; Animals; Behavior, Animal; Dialysis; Hydroxyindoleacetic Acid; Male; Motor Activity; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Serotonin | 1989 |
The effects of p-chloroamphetamine, a depletor of brain serotonin, on the performance of rats in two types of positively reinforced complex spatial discrimination tasks.
Topics: Amphetamines; Animals; Appetitive Behavior; Attention; Brain; Conditioning, Operant; Discrimination Learning; Hydroxyindoleacetic Acid; Male; Mental Recall; Motivation; Orientation; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin | 1989 |
p-Chloroamphetamine treatment modifies evoked responses to sinusoidal gratings in the pigeon optic tectum.
Topics: Analysis of Variance; Animals; Columbidae; Evoked Potentials; Female; Hydroxyindoleacetic Acid; Male; p-Chloroamphetamine; Photic Stimulation; Serotonin; Superior Colliculi | 1989 |
5-Hydroxytryptamine release in vivo from a cytoplasmic pool: studies on the 5-HT behavioural syndrome in reserpinized rats.
Topics: Animals; Behavior, Animal; Brain; Fluoxetine; Hydroxyindoleacetic Acid; Male; Metergoline; p-Chloroamphetamine; Pargyline; Rats; Rats, Inbred Strains; Reserpine; Serotonin | 1985 |
Effects of N-cyclopropyl-4-chloroamphetamine on brain serotonin metabolism in rats.
Topics: Amphetamine; Animals; Brain; Brain Chemistry; Chlorine; Cyclopropanes; Hydroxyindoleacetic Acid; In Vitro Techniques; Kinetics; Male; Mitochondria; Monoamine Oxidase; Monoamine Oxidase Inhibitors; p-Chloroamphetamine; Rats; Serotonin; Spectrometry, Fluorescence; Time Factors | 1973 |
Comparative effects of p-chloroamphetamine and 1-(p-chlorophenyl)piperazine on 5-hydroxyindole concentration in rat brain.
Topics: Amphetamines; Animals; Brain Chemistry; Depression, Chemical; Hydroxyindoleacetic Acid; Male; p-Chloroamphetamine; Piperazines; Rats; Serotonin; Structure-Activity Relationship; Time Factors | 1980 |
Effect of 2-(p-chlorophenyl)cyclopropylamine on 5-hydroxyindole concentration and monoamine oxidase activity in rat brain.
Topics: Amphetamines; Animals; Brain; Chromans; Hydroxyindoleacetic Acid; Male; Monoamine Oxidase Inhibitors; p-Chloroamphetamine; Rats; Serotonin | 1980 |
Circadian variation in the head twitch response produced by 5-methoxy-N1,N1-dimethyltryptamine and p-chloroamphetamine in the mouse.
Topics: Amphetamines; Animals; Behavior, Animal; Brain Chemistry; Circadian Rhythm; Hydroxyindoleacetic Acid; Male; Methoxydimethyltryptamines; Mice; p-Chloroamphetamine; Serotonin | 1981 |
Plasma luteinizing hormone in ovariectomized rats following pharmacologic manipulation of endogenous brain serotonin.
Topics: Animals; Brain; Castration; Female; Fenclonine; Fluoxetine; Hydroxyindoleacetic Acid; Luteinizing Hormone; p-Chloroamphetamine; Radioimmunoassay; Rats; Rats, Inbred Strains; Serotonin | 1981 |
In vivo voltammetry in the rat hippocampus as in index of drug effects on extraneuronal 5-HT.
Topics: Animals; Electrodes, Implanted; Electrophysiology; Fenclonine; Fluoxetine; Hippocampus; Hydroxyindoleacetic Acid; Microelectrodes; p-Chloroamphetamine; Probenecid; Rats; Serotonin; Tryptophan | 1981 |
Effect of salbutamol on the cerebral levels, uptake and turnover of serotonin.
Topics: Albuterol; Animals; Brain; Drug Interactions; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; p-Chloroamphetamine; Pargyline; Probenecid; Rats; Rats, Inbred Strains; Serotonin; Synaptosomes | 1982 |
Serotonin depletion by 5,7-dihydroxytryptamine or para-chloroamphetamine does not affect cancer anorexia.
Topics: 5,7-Dihydroxytryptamine; Amphetamines; Animals; Anorexia; Body Weight; Brain; Carcinoma 256, Walker; Dihydroxytryptamines; Energy Intake; Feeding and Eating Disorders; Humans; Hydroxyindoleacetic Acid; Hypothalamus; Male; Mesencephalon; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Serotonin; Tryptophan | 1983 |
Effect of cis and trans isomers of 1-amino-2-(p-chlorophenyl)cyclohexane, conformationally restricted analogs of p-chloroamphetamine, on 5-hydroxyindoles in rat brain.
Topics: Animals; Brain Chemistry; Hydroxyindoleacetic Acid; Male; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism; Structure-Activity Relationship | 1982 |
Drug-induced alterations in the efflux of 5-hydroxytryptamine and of 5-hydroxyindoleacetic acid into superfusates of the rat spinal cord.
Topics: Animals; Dose-Response Relationship, Drug; Fluoxetine; Hydroxyindoleacetic Acid; Male; p-Chloroamphetamine; Probenecid; Rats; Rats, Inbred Strains; Serotonin; Spinal Cord | 1983 |
Perturbation of rat brain serotonergic systems results in an inverse relation between substance P and serotonin concentrations measured in discrete nuclei.
Topics: Animals; Brain; Cell Nucleus; Fenclonine; Hydroxyindoleacetic Acid; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Serotonin; Substance P | 1983 |
Serotonergic involvement in phencyclidine-induced behaviors.
Topics: Animals; Brain; Brain Chemistry; Humans; Hydroxyindoleacetic Acid; Male; Methoxydimethyltryptamines; Monoamine Oxidase; Monoamine Oxidase Inhibitors; p-Chloroamphetamine; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Stereotyped Behavior; Tryptophan | 1984 |
Evaluation of nefopam as a monoamine uptake inhibitor in vivo in mice.
Topics: Animals; Biogenic Monoamines; Brain Chemistry; Dose-Response Relationship, Drug; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred ICR; Myocardium; Nefopam; Neurotransmitter Uptake Inhibitors; Norepinephrine; Oxidopamine; p-Chloroamphetamine; Selective Serotonin Reuptake Inhibitors; Serotonin | 1993 |
Involvement of central serotonergic pathways in analgesia elicited by salmon calcitonin in the mouse.
Topics: Analgesics; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Calcitonin; Fenclonine; Hydrazines; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Male; Mice; p-Chloroamphetamine; Pain Measurement; Serotonin; Spinal Cord | 1994 |
Effects of duloxetine, an antidepressant drug candidate, on concentrations of monoamines and their metabolites in rats and mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antidepressive Agents; Biogenic Monoamines; Brain; Dopamine; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred ICR; Monoamine Oxidase Inhibitors; Neurotransmitter Uptake Inhibitors; Norepinephrine; Oxidopamine; p-Chloroamphetamine; Rats; Rats, Sprague-Dawley; Serotonin; Thiophenes | 1994 |
p-Chloroamphetamine (PCA), 3,4-methylenedioxy-methamphetamine (MDMA) and d-fenfluramine pretreatment attenuates d-fenfluramine-evoked release of 5-HT in vivo.
Topics: Amphetamines; Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Dextroamphetamine; Fenfluramine; Hydroxyindoleacetic Acid; Male; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; p-Chloroamphetamine; Potassium; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Serotonin | 1994 |
In vivo electrochemical monitoring of serotonin in spinal dorsal horn with Nafion-coated multi-carbon fiber electrodes.
Topics: Allopurinol; Animals; Biosensing Techniques; Clorgyline; Electrochemistry; Electrodes; Fluorocarbon Polymers; Hydroxyindoleacetic Acid; Male; p-Chloroamphetamine; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Serotonin; Spinal Cord; Uric Acid; Xanthine Oxidase | 1995 |
5-HT loss in rat brain following 3,4-methylenedioxymethamphetamine (MDMA), p-chloroamphetamine and fenfluramine administration and effects of chlormethiazole and dizocilpine.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Behavior, Animal; Body Temperature; Brain Chemistry; Cerebral Cortex; Chlormethiazole; Dizocilpine Maleate; Fenfluramine; Hippocampus; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; p-Chloroamphetamine; Rats; Serotonin | 1993 |
In vivo brain dialysis study of the somatodendritic release of serotonin in the Raphe nuclei of the rat: effects of 8-hydroxy-2-(di-n-propylamino)tetralin.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dendrites; Dialysis; Hippocampus; Hydroxyindoleacetic Acid; Male; p-Chloroamphetamine; Potassium; Raphe Nuclei; Rats; Rats, Wistar; Serotonin | 1993 |
Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain.
Topics: Animals; Axons; Brain; Brain-Derived Neurotrophic Factor; Cell Survival; Hydroxyindoleacetic Acid; Immunohistochemistry; Male; Nerve Growth Factors; Nerve Regeneration; Nerve Tissue Proteins; Neurotrophin 3; p-Chloroamphetamine; Rats; Rats, Sprague-Dawley; Serotonin | 1995 |
Lack of neuroprotective effect of sigma receptor ligands in the neurotoxicity of p-chloroamphetamine in rat brain.
Topics: Animals; Anisoles; Antitussive Agents; Cerebral Cortex; Dextromethorphan; Haloperidol; Hydroxyindoleacetic Acid; Ligands; Male; p-Chloroamphetamine; Propylamines; Rats; Rats, Sprague-Dawley; Receptors, sigma; Serotonin; Serotonin Agents | 1995 |
Effect of p-chlorophenylalanine at moderate dosage on 5-HT and 5-HIAA concentrations in brain regions of control and p-chloroamphetamine treated rats.
Topics: Animals; Brain; Drug Interactions; Fenclonine; Hydroxyindoleacetic Acid; Male; p-Chloroamphetamine; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Agents | 1996 |
Excessive serotonin release, not depletion, leads to memory impairments in rats.
Topics: Animals; Avoidance Learning; Brain; Dopamine; Dose-Response Relationship, Drug; Hydroxyindoleacetic Acid; Male; Memory; p-Chloroamphetamine; Rats; Rats, Sprague-Dawley; Serotonin | 1996 |
Studies on the mechanism of p-chloroamphetamine neurotoxicity.
Topics: Animals; Brain; Clorgyline; Dopamine; Fever; Hydroxyindoleacetic Acid; Indans; Male; Monoamine Oxidase Inhibitors; N-Methyl-3,4-methylenedioxyamphetamine; Neuroprotective Agents; Neurotoxins; p-Chloroamphetamine; Paroxetine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Selegiline; Serotonin; Serotonin Agents | 1996 |
Lack of neuroprotective effect of sigma receptor ligands in the neurotoxicity of p-chloroamphetamine in rat brain.
Topics: Animals; Brain; Haloperidol; Hydroxyindoleacetic Acid; Ligands; Male; p-Chloroamphetamine; Rats; Rats, Sprague-Dawley; Receptors, sigma; Serotonin | 1996 |
Effect of prenatal fluoxetine (Prozac) exposure on brain serotonin neurons in prepubescent and adult male rat offspring.
Topics: Age Factors; Animals; Brain; Female; Fetus; Fluoxetine; Frontal Lobe; Hydroxyindoleacetic Acid; Male; Mesencephalon; p-Chloroamphetamine; Pregnancy; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin | 1997 |
The spin trap reagent PBN attenuates degeneration of 5-HT neurones in rat brain induced by p-chloroamphetamine but not fenfluramine.
Topics: Animals; Body Temperature; Brain; Brain Chemistry; Cyclic N-Oxides; Fenfluramine; Hydroxyindoleacetic Acid; Male; Nerve Degeneration; Neurons; Nitrogen Oxides; p-Chloroamphetamine; Paroxetine; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Spin Labels; Spin Trapping | 1996 |
Cell body infusions of brain-derived neurotrophic factor increase forebrain dopamine release and serotonin metabolism determined with in vivo microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain-Derived Neurotrophic Factor; Dextroamphetamine; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Infusions, Parenteral; Kinetics; Male; Mesencephalon; Microdialysis; Nerve Growth Factors; Neurotrophin 3; p-Chloroamphetamine; Prosencephalon; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Serotonin | 1998 |
p-Chloroamphetamine- and d-fenfluramine-induced brain serotonin release in experimental portal-systemic encephalopathy.
Topics: Animals; Brain; Cerebral Cortex; Extracellular Space; Fenfluramine; Hepatic Encephalopathy; Hydroxyindoleacetic Acid; Male; Osmolar Concentration; p-Chloroamphetamine; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Agents | 1997 |
Blockade of muscarinic, rather than nicotinic, receptors impairs attention, but does not interact with serotonin depletion.
Topics: 5,7-Dihydroxytryptamine; Animals; Attention; Behavior, Animal; Brain; Cholinergic Antagonists; Cognition; Hydroxyindoleacetic Acid; Injections, Intraventricular; Male; Muscarinic Antagonists; Nerve Fibers; Neurons; Nicotinic Antagonists; p-Chloroamphetamine; Photic Stimulation; Rats; Rats, Wistar; Reaction Time; Receptors, Cholinergic; Receptors, Muscarinic; Receptors, Nicotinic; Serotonin; Serotonin Agents; Task Performance and Analysis | 2000 |
Serotonin depletion and barrel cortex development: impact of growth impairment vs. serotonin effects on thalamocortical endings.
Topics: Aging; Animals; Animals, Newborn; Body Weight; Brain; Fenclonine; Hydroxyindoleacetic Acid; Organ Size; p-Chloroamphetamine; Rats; Rats, Inbred Lew; Serotonin; Somatosensory Cortex; Vibrissae | 2000 |
Neurochemical changes in brain serotonin neurons in immature and adult offspring prenatally exposed to cocaine.
Topics: Age Factors; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Female; Hydroxyindoleacetic Acid; Neurons; Norepinephrine; p-Chloroamphetamine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Agents | 2000 |
Stimulated serotonin release from hyperinnervated terminals subsequent to neonatal dopamine depletion regulates striatal tachykinin, but not enkephalin gene expression.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Cerebral Ventricles; Corpus Striatum; Desipramine; Dopamine; Enkephalins; Gene Expression Regulation; Hydroxyindoleacetic Acid; Injections, Intraventricular; Oxidopamine; p-Chloroamphetamine; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Serotonin; Tachykinins; Transcription, Genetic | 2000 |
Acute melatonin and para-chloroamphetamine interactions on pineal, brain and serum serotonin levels as well as stress hormone levels.
Topics: Adrenocorticotropic Hormone; Amphetamine-Related Disorders; Animals; Brain; Corticosterone; Drug Interactions; Hydroxyindoleacetic Acid; Melatonin; Methamphetamine; Neurons; Neurotoxins; Oxidative Stress; p-Chloroamphetamine; Pineal Gland; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Agents; Stress, Physiological | 2001 |
Partial denervation of the locus coeruleus projections by treatment with the selective neurotoxin DSP-4 potentiates the long-term effect of parachloroamphetamine on 5-hydroxytryptamine metabolism in the rat.
Topics: Animals; Benzylamines; Cerebellum; Cerebral Cortex; Denervation; Dose-Response Relationship, Drug; Drug Interactions; Efferent Pathways; Hippocampus; Hydroxyindoleacetic Acid; Hypothalamus; Locus Coeruleus; Male; Neurotoxins; p-Chloroamphetamine; Presynaptic Terminals; Raphe Nuclei; Rats; Rats, Wistar; Serotonin; Serotonin Agents; Sympathomimetics | 2002 |
High-dose fenfluramine administration decreases serotonin transporter binding, but not serotonin transporter protein levels, in rat forebrain.
Topics: Animals; Blotting, Western; Carrier Proteins; Fenfluramine; Hydroxyindoleacetic Acid; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; p-Chloroamphetamine; Prosencephalon; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins | 2003 |
Increased behavioural activity of rats in forced swimming test after partial denervation of serotonergic system by parachloroamphetamine treatment.
Topics: Animals; Behavior, Animal; Biogenic Monoamines; Brain Chemistry; Denervation; Depression; Dopamine; Dose-Response Relationship, Drug; Hydroxyindoleacetic Acid; Male; Norepinephrine; p-Chloroamphetamine; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta; Receptors, Serotonin; Serotonin; Serotonin Agents; Swimming | 2004 |
Serotoninergic system blockage in the prepubertal rat inhibits spermatogenesis development.
Topics: Animals; Apoptosis; Depression, Chemical; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Histocytochemistry; Hydroxyindoleacetic Acid; Hypothalamus; In Situ Nick-End Labeling; Luteinizing Hormone; Male; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Seminiferous Epithelium; Serotonin; Serotonin Antagonists; Sexual Maturation; Spermatogenesis; Spermatozoa | 2005 |
Central serotonin depletion affects rat brain areas differently: a qualitative and quantitative comparison between different treatment schemes.
Topics: Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Drug Administration Schedule; Drug Interactions; Fenfluramine; Hydroxyindoleacetic Acid; Male; p-Chloroamphetamine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents | 2006 |
Relationship between limbic and cortical 5-HT neurotransmission and acquisition and reversal learning in a go/no-go task in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amygdala; Animals; Brain; Cerebral Cortex; Conditioning, Operant; Discrimination Learning; Dopamine; Feeding Behavior; Hippocampus; Hydroxyindoleacetic Acid; Limbic System; Male; Motor Activity; Nucleus Accumbens; p-Chloroamphetamine; Prefrontal Cortex; Rats; Rats, Wistar; Reversal Learning; Serotonin; Serotonin Antagonists; Stress, Psychological; Synaptic Transmission | 2006 |
Rat behavior after chronic variable stress and partial lesioning of 5-HT-ergic neurotransmission: effects of citalopram.
Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Biogenic Monoamines; Brain Injuries; Citalopram; Disease Models, Animal; Drug Interactions; Exploratory Behavior; Food Preferences; Frontal Lobe; Hydroxyindoleacetic Acid; Interpersonal Relations; Male; p-Chloroamphetamine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Stress, Psychological; Sucrose; Swimming | 2008 |
Prepubertal male rats with high rates of germ-cell apoptosis present exacerbated rates of germ-cell apoptosis after serotonin depletion.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Gene Expression Regulation, Developmental; Hydroxyindoleacetic Acid; Kinetics; Male; p-Chloroamphetamine; Progesterone Reductase; Proto-Oncogene Proteins c-bcl-2; Random Allocation; Rats; Receptors, Androgen; Receptors, Cell Surface; RNA, Messenger; Serotonin; Serotonin Agents; Sexual Maturation; Spermatogenesis; Spermatogonia | 2016 |