hydroxyindoleacetic acid has been researched along with morphine in 99 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 69 (69.70) | 18.7374 |
| 1990's | 20 (20.20) | 18.2507 |
| 2000's | 8 (8.08) | 29.6817 |
| 2010's | 2 (2.02) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bensemana, D; Gascon, AL | 2 |
| Oka, T; Sawa, A | 1 |
| Abdel-Halim, MS; Anggård, E; Sjöquist, B | 1 |
| Fisher, LA; Lytle, LD; Messing, RB; Phebus, L | 1 |
| Ahtee, L; Carlsson, A | 1 |
| Flinchbaugh, C; Messing, RB; Waymire, JC | 1 |
| Murakami, H; Shiomi, H; Takagi, H | 1 |
| Herz, A; Papeschi, R; Theiss, P | 2 |
| Clermont, MJ; Collu, R; Ducharme, JR | 1 |
| Huang, JT; Wajda, IJ | 1 |
| Ng, LK; Pérez-Cruet, J; Thoa, NB | 1 |
| Pleuvry, BJ | 1 |
| Auerbach, SB; Grauer, SM; Tao, R | 1 |
| Basbaum, AI; Brown, JL; Matos, FF; Rollema, H | 1 |
| Carlson, JN; Glick, SD; Keller, RW; Merski, C; Steindorf, S; Wang, S | 1 |
| Hoganson, DA; Hughes, RA; Sufka, KJ | 1 |
| Ishikawa, K; Kogure, M; Kubo, T; Shibanoki, S | 1 |
| Besson, JM; Puig, S; Rivot, JP | 2 |
| Fujimura, H; Niwa, M; Nose, T; Nozaki, M; Tsurumi, K | 1 |
| Franklin, KB; Kelly, SJ | 1 |
| Suzuki, Y; Taguchi, K | 1 |
| Ahtee, L; Attila, P; Lauhakangas, V; Sipilä, J; Solkinen, A | 1 |
| Bero, LA; Kuhn, CM | 1 |
| Chiang, CY; Xiang, XK | 1 |
| Borque-Ibarra, M; González Hernandez, MJ; González Maté, A; González-Navarro, A; Molinero Aparicio, T; Zimman Mansfeld, H | 1 |
| Boadle-Biber, MC; Johannessen, JN; Narasimhachari, N; Phan, TH | 1 |
| Melcón, LF; Seijo, F; Simó, RM | 1 |
| Fatela, LV; Gozalo, A; Lobato, RD; Madrid, JL | 1 |
| Fatela, LV; Gozalo, A; Lobato, RD; Madrid, JL; Rivas, JJ; Sarabia, R | 1 |
| Clark, JT; Gabriel, SM; Kalra, PS; Kalra, SP; Simpkins, JW | 1 |
| Daval, G; Fattaccini, CM; Gozlan, H; Hamon, M; Spampinato, U | 1 |
| Ahtee, L; Attila, LM; Carlson, KR; Haikala, H | 1 |
| Hole, K; Hunskaar, S; Rosland, JH | 1 |
| Abbott, FV; Young, SN | 1 |
| Esposito, E; Romandini, S; Samanin, R; Spampinato, U | 1 |
| Evron, S; Shohami, E | 1 |
| Commissiong, JW | 2 |
| Ahtee, L; Kääriäinen, I | 1 |
| Hosoya, E; Maruyama, Y; Takemori, AE | 1 |
| Papeschi, R; Theiss, P | 1 |
| Gessa, GL; Perez-Cruet, J; Stern, S; Tagliamonte, A; Tagliamonte, P | 1 |
| Samanin, R; Valzelli, L | 1 |
| Cartwright, C; Schulz, R | 1 |
| Garattini, S; Kon, S; Samanin, R | 1 |
| Goodlet, I; Sugrue, MF | 2 |
| Buxbaum, DM; Sanders-Busch, E; Yarbrough, GG | 1 |
| Fujimoto, JM; Lech, JJ; Zamiatowski, R | 1 |
| Buxbaum, DM; Sanders-Bush, E; Yarbrough, GG | 2 |
| Blake, DE; Haubrich, DR | 1 |
| Ciofalo, FR | 1 |
| Gessa, GL; Tagliamonte, A | 1 |
| Bowers, MB; Kleber, HD | 1 |
| Fennessy, MR; Lee, JR | 1 |
| Bloom, FE; Costa, E | 1 |
| Gumulka, W; Samanin, R; Valzelli, L | 1 |
| Loh, HH; Shen, FH; Way, EL | 1 |
| Sharman, DF | 1 |
| Ahtee, L | 1 |
| Besson, JM; Coudert, D; Godefroy, F; Weil-Fugazza, J | 1 |
| Isom, GE; Meldrum, MJ | 1 |
| Snelgar, RS; Vogt, M | 1 |
| Fan, SG; Shutt, AJ; Vogt, M | 1 |
| Kamata, K; Kameyama, T; Nabeshima, T; Okuyama, S; Sakakibara, S; Ukai, M; Yamaguchi, K | 1 |
| Botting, R; Morinan, A | 1 |
| Vasko, MR; Vogt, M | 1 |
| Han, JS; Li, SJ; Tang, J | 1 |
| Ishikawa, K; McGaugh, JL; Shibanoki, S | 1 |
| Groppetti, A; Olgiati, VR; Parenti, M; Tirone, F | 1 |
| Romandini, S; Samanin, R | 1 |
| Bardon, T; Ruckebusch, M | 1 |
| Ghosh, S; Poddar, MK | 1 |
| Barraclough, CA; He, JR; Molnar, J | 1 |
| Auerbach, SB; Tao, R | 1 |
| Ashby, CR; Eberle, WF; Strecker, RE | 1 |
| Jung, JS; Kim, YH; Song, DK; Suh, HW | 1 |
| Basbaum, AI; Levine, JD; Matos, FF; Rollema, H; Taiwo, YO | 1 |
| Choi, SR; Hong, HE; Jung, JS; Kim, YH; Song, DK; Suh, HW; Wie, MB | 1 |
| Javelle, N; Lambás-Señas, L; Renaud, B | 1 |
| Kato, M; Shigenaga, T; Taguchi, K | 1 |
| De Natale, G; Desole, MS; Enrico, P; Esposito, G; Miele, E; Miele, M; Migheli, R; Mura, MA; Serra, P | 1 |
| Borgeat, A; Fahti, M; Hasler, P | 1 |
| Chen, JC; Huang, KS; Li, JY; Liang, KW; Lin, MY; Tan, PP; Wong, CH | 1 |
| Ottani, A; Pini, LA; Sandrini, M; Vitale, G | 1 |
| Chen, JC; Chen, YL; Huang, EY; Li, JY; Lin, YC; Tan, PP; Wong, CH | 1 |
| Abe, K; Chuma, T; Kato, M; Miyamoto, K; Miyatake, T; Taguchi, K; Utsunomiya, I | 1 |
| Borszcz, GS; Munn, EM | 1 |
| Basbaum, AI; Taylor, BK | 1 |
| Dickès-Coopman, A; Dutriez-Casteloot, I; Laborie, C; Lesage, J; Montel, V; Vieau, D | 1 |
| Ahmed, SH; Barbano, MF; Cador, M; Stinus, L | 1 |
| Ahtee, L; Airavaara, M; Leiviskä, R; Piepponen, TP; Relander, TR; Tuominen, RK; Vihavainen, T | 1 |
| Alvarez, RG; Brizuela, NO; García, EH; Guzmán, DC; Mejía, GB; Olguín, HJ | 1 |
| Nagai, J; Nakazawa, T; Nishiyori, M; Ueda, H | 1 |
| Garcia, EH; Gonzalez, JA; Guzman, DC; Labra Ruiz, NA; Mejia, GB; Olguin, HJ | 1 |
1 trial(s) available for hydroxyindoleacetic acid and morphine
| Article | Year |
|---|---|
Gynecologic laparoscopic surgery is not associated with an increase of serotonin metabolites excretion.
Topics: Adult; Aged; Analgesics, Opioid; Female; Fentanyl; Gynecologic Surgical Procedures; Humans; Hydroxyindoleacetic Acid; Laryngoscopy; Middle Aged; Morphine; Postoperative Nausea and Vomiting; Serotonin | 1998 |
98 other study(ies) available for hydroxyindoleacetic acid and morphine
| Article | Year |
|---|---|
An attempt to correlated analgesia to changes in brain neuromediators in rats.
Topics: Analgesia; Analgesics; Animals; Brain Stem; Dopamine; Dronabinol; Hydroxyindoleacetic Acid; Male; Morphine; Neurotransmitter Agents; Norepinephrine; Rats; Reaction Time; Serotonin; Sodium Salicylate | 1975 |
Effects of narcotic analgesics on serotonin metabolism in brain of rats and mice.
Topics: Analgesics, Opioid; Animals; Atropine; Brain; Drug Interactions; Fenclonine; Hydroxyindoleacetic Acid; Male; Meperidine; Methadone; Mice; Mice, Inbred ICR; Morphine; Naloxone; Pargyline; Probenecid; Rats; Serotonin | 1976 |
Prostaglandin synthesis inhibition and monoamine metabolites in the rat brain.
Topics: Animals; Apomorphine; Brain; Chlorpromazine; Corpus Striatum; Gas Chromatography-Mass Spectrometry; Glycols; Homovanillic Acid; Hydroxyindoleacetic Acid; Indomethacin; Male; Methoxyhydroxyphenylglycol; Morphine; Olfactory Bulb; Phenylacetates; Rats | 1979 |
Analgesic effect of fluoxetine hydrochloride (Lilly 110140), a specific inhibitor of serotonin uptake.
Topics: Analgesics; Animals; Behavior, Animal; Brain; Depression, Chemical; Fenclonine; Hydroxyindoleacetic Acid; Male; Morphine; Naloxone; Phenyl Ethers; Propylamines; Rats; Serotonin; Time Factors | 1975 |
Dual action of methadone on 5-HT synthesis and metabolism.
Topics: 5-Hydroxytryptophan; Animals; Brain; Dihydroxyphenylalanine; Hydroxyindoleacetic Acid; Male; Methadone; Morphine; Naloxone; Probenecid; Rats; Serotonin; Tryptophan; Tyrosine | 1979 |
Tryptophan and 5-hydroxyindoles in different CNS regions following acute morphine.
Topics: Animals; Brain Chemistry; Hydroxyindoleacetic Acid; Male; Morphine; Naloxone; Rats; Serotonin; Tryptophan | 1978 |
Relationship between analgesia and turnover of brain biogenic amines.
Topics: Analgesia; Analgesics; Animals; Biogenic Amines; Brain; Catecholamines; Dronabinol; Hydroxyindoleacetic Acid; Male; Methyltyrosines; Morphine; Probenecid; Rats; Serotonin; Sodium Salicylate | 1978 |
Morphine analgesia and the bulbospinal serotonergic system: increase in concentration of 5-hydroxyindoleacetic acid in the rat spinal cord with analgesics.
Topics: Analgesics; Animals; Hydroxyindoleacetic Acid; Male; Morphine; Narcotic Antagonists; Neurons; Probenecid; Rats; Serotonin; Spinal Cord; Time Factors; Tryptophan Hydroxylase | 1978 |
Effects of morphine on the turnover of brain catecholamines and serotonin in rats-chronic morphine administration.
Topics: 3-Methoxy-4-hydroxyphenylethanol; Animals; Brain; Catecholamines; Dopamine; Drug Implants; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Methyltyrosines; Morphine; Norepinephrine; Rats; Serotonin; Time Factors; Vocalization, Animal | 1975 |
Effects of thyrotropin-releasing hormone on prolactin, growth hormone and corticosterone secretions in adult male rats treated with pentobarbital or morphine.
Topics: Animals; Brain; Corticosterone; Growth Hormone; Hydroxyindoleacetic Acid; Injections, Intraventricular; Male; Morphine; Pentobarbital; Prolactin; Rats; Serotonin; Thyrotropin-Releasing Hormone | 1976 |
The effects of morphine on the accumulation of homovanillic and 5-hydroxyindoleacetic acids in the choroid plexus of rats.
Topics: Amino Acids; Animals; Choroid Plexus; Drug Interactions; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Morphinans; Morphine; Phenylacetates; Probenecid; Rats; Time Factors | 1977 |
Acute effects of heroin and morphine on newly synthesized serotonin in rat brain.
Topics: Animals; Behavior, Animal; Brain; Brain Stem; Cerebral Cortex; Corpus Striatum; Diencephalon; Enzyme Induction; Heroin; Hydroxyindoleacetic Acid; Kinetics; Male; Morphine; Pargyline; Rats; Serotonin; Tryptophan; Tryptophan Hydroxylase | 1975 |
Mouse brain catecholamines, 5-hydroxytryptamine and the antinociceptive activity of pethidine.
Topics: Analgesics; Animals; Brain Chemistry; Catecholamines; Dopamine; Female; Hydroxyindoleacetic Acid; Meperidine; Mice; Morphine; Naloxone; Norepinephrine; Reaction Time; Reserpine; Serotonin | 1975 |
Morphine induces an increase in extracellular serotonin in the rat diencephalon.
Topics: Animals; Behavior, Animal; Catalepsy; Chromatography, High Pressure Liquid; Dialysis; Diencephalon; Electrochemistry; Hydroxyindoleacetic Acid; Male; Morphine; Naltrexone; Rats; Rats, Sprague-Dawley; Reaction Time; Serotonin | 1992 |
Do opioids evoke the release of serotonin in the spinal cord? An in vivo microdialysis study of the regulation of extracellular serotonin in the rat.
Topics: Amphetamine; Animals; Dialysis; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Extracellular Space; Fluoxetine; Hydroxyindoleacetic Acid; Injections, Intraventricular; Male; Morphine; Narcotics; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Serotonin; Spinal Cord; Tetrodotoxin | 1992 |
Neurochemical predisposition to self-administer morphine in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cerebral Cortex; Corpus Striatum; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Injections, Intravenous; Morphine; Morphine Dependence; Nucleus Accumbens; Rats; Rats, Inbred Strains; Self Administration; Substantia Nigra | 1992 |
Central monoaminergic changes induced by morphine in hypoalgesic and hyperalgesic strains of domestic fowl.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Brain Chemistry; Chickens; Chromatography, High Pressure Liquid; Hydroxyindoleacetic Acid; Inflammation; Morphine; Pain; Species Specificity | 1992 |
Naloxone affects both pharmacokinetics and pharmacodynamics of morphine. Application of direct correlation analysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Corpus Striatum; Homovanillic Acid; Hydroxyindoleacetic Acid; Hypothalamus; Male; Methoxyhydroxyphenylglycol; Morphine; Naloxone; Protein Binding; Rats; Rats, Inbred Strains; Statistics as Topic; Sulfobromophthalein | 1991 |
Femoxetine blocks the morphine-induced increase in 5-HT metabolism, as measured by in vivo voltammetry in the nucleus raphe magnus of freely-moving rats.
Topics: Animals; Electrochemistry; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Morphine; Oxidation-Reduction; Piperidines; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists | 1991 |
Effects of butorphanol and its metabolites on the levels of monoamines and their metabolites in the rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Brain; Butorphanol; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Morphinans; Morphine; Norepinephrine; Pentazocine; Rats; Rats, Inbred Strains; Serotonin | 1985 |
Sympathetic control of tryptophan uptake and morphine analgesia in stressed rats.
Topics: Analgesia; Animals; Guanethidine; Hydroxyindoleacetic Acid; Male; Morphine; Pain; Rats; Restraint, Physical; Serotonin; Stress, Psychological; Sympathetic Nervous System; Tryptophan | 1986 |
In vivo voltammetric studies of the effect of morphine on the serotonergic system in the cat spinal cord.
Topics: 5-Hydroxytryptophan; Animals; Cats; Hydroxyindoleacetic Acid; Indoles; Morphine; Neural Pathways; Raphe Nuclei; Serotonin; Spinal Cord; Synaptic Transmission | 1986 |
The fall of homovanillic acid and 5-hydroxyindoleacetic acid concentrations in brains of mice withdrawn from repeated morphine treatment and their restoration by acute morphine administration.
Topics: Animals; Body Weight; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Morphine; Morphine Dependence; Probenecid; Serotonin; Substance Withdrawal Syndrome; Telencephalon | 1987 |
Role of serotonin in opiate-induced prolactin secretion and antinociception in the developing rat.
Topics: 5,7-Dihydroxytryptamine; Aging; Animals; Animals, Newborn; Cyproheptadine; Hydroxyindoleacetic Acid; Hypothalamus; Morphine; Pain; Prolactin; Rats; Rats, Inbred Strains; Serotonin | 1987 |
Does morphine enhance the release of 5-hydroxytryptamine in the rat spinal cord? An in vivo differential pulse voltammetry study.
Topics: Animals; Electrochemistry; Hydroxyindoleacetic Acid; Male; Morphine; Probenecid; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Spinal Cord; Stereoisomerism; Tryptophan; Urate Oxidase | 1987 |
[Use of beta-endorphin in pain in cancer patients].
Topics: beta-Endorphin; Dose-Response Relationship, Drug; Drug Evaluation; Endorphins; Humans; Hydroxyindoleacetic Acid; Injections, Spinal; Morphine; Neoplasms; Pain Measurement; Pain, Intractable | 1987 |
Activation of cortical tryptophan hydroxylase by acute morphine treatment: blockade by 6-hydroxydopamine.
Topics: Alkaline Phosphatase; Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Electrochemistry; Enzyme Activation; Gas Chromatography-Mass Spectrometry; Hydroxydopamines; Hydroxyindoleacetic Acid; Kinetics; Male; Morphine; Naloxone; Norepinephrine; Oxidopamine; Rats; Rats, Inbred Strains; Tryptophan Hydroxylase | 1987 |
[Determination of the levels of methionine enkephalin in the blood and CSF and of 5-hydroxyindoleacetic acid in the CSF, following intrathecal administration of morphine].
Topics: Aged; Enkephalin, Methionine; Female; Humans; Hydroxyindoleacetic Acid; Injections, Spinal; Male; Middle Aged; Morphine; Neoplasms | 1985 |
Intrathecal therapy: rationale, technique, clinical results.
Topics: Adolescent; Adult; Aged; Child; Cisterna Magna; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infusion Pumps; Injections, Spinal; Male; Middle Aged; Morphine; Neoplasms; Pain, Intractable | 1987 |
Intraventricular morphine for intractable cancer pain: rationale, methods, clinical results.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infusion Pumps; Injections, Intraventricular; Middle Aged; Morphine; Neoplasms; Pain, Intractable | 1987 |
Chronic morphine and testosterone treatment: effects on norepinephrine and serotonin metabolism and gonadotropin secretion in male rats.
Topics: Animals; Brain; Follicle Stimulating Hormone; Hydroxyindoleacetic Acid; Luteinizing Hormone; Male; Morphine; Norepinephrine; Normetanephrine; Rats; Reference Values; Serotonin; Silicone Elastomers; Testosterone | 1988 |
Dopamine receptor subsensitivity in the substantia nigra after chronic morphine treatment in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Autoradiography; Behavior, Animal; Chromatography, High Pressure Liquid; Dopamine; Hydroxyindoleacetic Acid; Injections, Subcutaneous; Male; Morphine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Serotonin; Substantia Nigra | 1988 |
Changes in brain monoamine metabolism during withdrawal from chronic oral self-administration of morphine and in response to a morphine challenge in the withdrawn state.
Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Oral; Animals; Biogenic Amines; Brain; Dopamine; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Morphine; Rats; Rats, Inbred Strains; Self Administration; Substance Withdrawal Syndrome | 1989 |
Mechanisms of orphenadrine-induced antinociception in mice: a role for serotonergic pathways.
Topics: Analgesics; Animals; Behavior, Animal; Dopamine; Fenclonine; Hydroxyindoleacetic Acid; Male; Mice; Morphine; Naloxone; Norepinephrine; Orphenadrine; Pain Measurement; Psychomotor Performance; Reaction Time; Serotonin; Synaptosomes | 1989 |
Effect of 5-hydroxytryptamine precursors on morphine analgesia in the formalin test.
Topics: 5-Hydroxytryptophan; Analgesia; Animals; Behavior, Animal; Central Nervous System; Dose-Response Relationship, Drug; Drug Synergism; Formaldehyde; Hydroxyindoleacetic Acid; Male; Morphine; Pain Measurement; Rats; Serotonin; Tryptophan | 1988 |
Changes of serotonin and dopamine metabolism in various forebrain areas of rats injected with morphine either systemically or in the raphe nuclei dorsalis and medianus.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Cerebral Cortex; Corpus Striatum; Diencephalon; Dopamine; Fenclonine; Hippocampus; Homovanillic Acid; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Morphine; Nucleus Accumbens; Raphe Nuclei; Rats; Serotonin | 1985 |
Intrathecal morphine induces myoclonic seizures in the rat.
Topics: Analgesics; Animals; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Injections, Spinal; Male; Morphine; Myoclonus; Naloxone; Piloerection; Rats; Serotonin; Spinal Cord | 1985 |
Monoamine metabolites: their relationship and lack of relationship to monoaminergic neuronal activity.
Topics: Animals; Antipsychotic Agents; Biogenic Amines; Biotransformation; Central Nervous System; Dopamine; Electric Stimulation; Humans; Hydroxyindoleacetic Acid; Morphine; Nerve Endings; Neurons; Neurotransmitter Agents; Raphe Nuclei | 1985 |
5-hydroxytryptamine in platelets and brain of rabbits treated chronically with imipramine, morphine or methadone.
Topics: Animals; Blood Platelets; Brain Chemistry; Hydroxyindoleacetic Acid; Imipramine; Male; Methadone; Morphine; Rabbits; Serotonin; Time Factors | 1973 |
[Gas chromatographic analysis of central biogenic amines and its application. 1].
Topics: Animals; Biogenic Amines; Brain; Brain Chemistry; Chromatography, Gas; Dopamine; Fenclonine; Hydroxyindoleacetic Acid; Methods; Mice; Morphine; Norepinephrine; Pargyline; Serotonin; Solvents | 1973 |
Proceedings: Turnover of biogenic amines after acute and chronic morphine treatment in rats.
Topics: Acetamides; Animals; Biogenic Amines; Brain; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Methyltyrosines; Morphine; Norepinephrine; Probenecid; Rats; Serotonin; Time Factors | 1974 |
Effect of psychotropic drugs on tryptophan concentration in the rat brain.
Topics: Alkaloids; Animals; Apomorphine; Aporphines; Body Temperature; Brain Chemistry; Butyrates; Chlorpromazine; Cold Temperature; Cyclic AMP; Dextroamphetamine; Fenclonine; Fenfluramine; Haloperidol; Hot Temperature; Hydroxybutyrates; Hydroxyindoleacetic Acid; Lithium; Male; Methyltyrosines; Morphine; Nucleosides; Phenelzine; Phenmetrazine; Probenecid; Rats; Reserpine; Serotonin; Tryptophan; Tyrosine | 1971 |
Serotoninergic neurotransmission and morphine activity.
Topics: Animals; Behavior, Animal; Body Temperature; Brain Chemistry; Drug Interactions; Electric Stimulation; Escape Reaction; Female; Hydroxyindoleacetic Acid; Mesencephalon; Morphine; Nitrophenols; Phentolamine; Rats; Serotonin; Synaptic Transmission; Vocalization, Animal | 1972 |
Effect of morphine on serotonin release from myenteric plexus of the guinea pig.
Topics: Animals; Carbon Radioisotopes; Chromatography, Thin Layer; Dopamine; Drug Tolerance; Electric Stimulation; Guinea Pigs; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Monoamine Oxidase; Morphine; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Neuromuscular Junction; Serotonin; Synaptic Transmission; Tetrodotoxin; Time Factors; Tritium | 1974 |
Abolition of the morphine effect on body temperature in midbrain raphe lesioned rats.
Topics: Animals; Body Temperature; Brain; Depression, Chemical; Dinitrophenols; Female; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Mesencephalon; Morphine; Phentolamine; Rats; Serotonin; Stimulation, Chemical; Telencephalon | 1972 |
Serotonin and dopamine turnover after acute and chronic morphine administration.
Topics: Animals; Brain; Brain Chemistry; Dopamine; Drug Tolerance; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Morphine; Morphine Dependence; Probenecid; Rats; Serotonin; Substance Withdrawal Syndrome | 1974 |
Effect of acutely administered analgesic drugs on rat brain serotonin turnover.
Topics: Analgesics; Animals; Brain; Brain Chemistry; Clomipramine; Dopamine; Hydroxyindoleacetic Acid; Kinetics; Male; Meperidine; Methadone; Morphine; Naloxone; Nialamide; Norepinephrine; Pargyline; Pentazocine; Rats; Serotonin; Stimulation, Chemical; Tranylcypromine; Tryptophan | 1974 |
Effects of acutely administered analgesic drugs on rat brain 5-hydroxytryptamine turnover.
Topics: Analgesics; Animals; Brain; Brain Chemistry; Hydroxyindoleacetic Acid; Male; Meperidine; Methadone; Morphine; Pargyline; Pentazocine; Probenecid; Rats; Serotonin | 1972 |
Increased serotonin turnover in acutely morphine-treated mice.
Topics: Animals; Brain Chemistry; Cerebral Cortex; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred ICR; Morphine; Probenecid; Serotonin; Time Factors; Tritium; Tryptophan | 1972 |
A site of action of novobiocin in inhibiting renal tubular transport of drugs in the chicken.
Topics: Aminohippuric Acids; Animals; Binding Sites; Carbon Isotopes; Catechols; Chickens; Female; Hydroxyindoleacetic Acid; Kidney; Kidney Tubules; Morphine; Novobiocin; Perfusion; Quaternary Ammonium Compounds; Saphenous Vein; Serotonin; Sulfates; Time Factors; Tritium | 1973 |
Biogenic amines and narcotic effects. II. Serotonin turnover in the rat after acute and chronic morphine administration.
Topics: Animals; Brain Chemistry; Drug Tolerance; Hydroxyindoleacetic Acid; Male; Morphine; Motor Activity; Naloxone; Pargyline; Probenecid; Rats; Serotonin; Time Factors; Tritium; Tryptophan; Tryptophan Hydroxylase | 1973 |
Modification of serotonin metabolism in rat brain after acute or chronic administration of morphine.
Topics: Animals; Brain; Brain Chemistry; Drug Tolerance; Fluorometry; Hydroxyindoleacetic Acid; Male; Morphine; Pargyline; Probenecid; Rats; Reaction Time; Serotonin; Time Factors | 1973 |
Methadone inhibition of 3H-5-hydroxytryptamine uptake by synaptosomes.
Topics: Animals; Brain; Centrifugation, Density Gradient; Cold Temperature; Dinitrophenols; Dose-Response Relationship, Drug; Hydroxyindoleacetic Acid; Imipramine; In Vitro Techniques; Kinetics; Male; Methadone; Monoamine Oxidase Inhibitors; Morphine; Naloxone; Ouabain; Potassium Chloride; Rabbits; Serotonin; Serotonin Antagonists; Sucrose; Synaptosomes; Tritium | 1974 |
Possible role of free serum tryptophan in the control of brain tryptophan level and serotonin synthesis.
Topics: Amino Acids; Animals; Apomorphine; Blood-Brain Barrier; Brain; Chlorpromazine; Cold Temperature; Desipramine; Fenfluramine; Haloperidol; Hydroxyindoleacetic Acid; Kinetics; Methyltyrosines; Morphine; Neurons; Phenelzine; Protein Binding; Rats; Serotonin; Stimulation, Chemical; Tryptophan; Tryptophan Hydroxylase | 1974 |
Methadone increases mouse brain 5-hydroxyindoleacetic acid.
Topics: Animals; Brain; Hydroxyindoleacetic Acid; Methadone; Mice; Morphine; Pargyline; Probenecid; Serotonin; Stimulation, Chemical | 1971 |
Comparison of the dose-response effects of morphine on brain amines, analgesia and activity in mice.
Topics: Amines; Analgesia; Animals; Brain; Brain Chemistry; Dopamine; Female; Hydroxyindoleacetic Acid; Injections, Subcutaneous; Male; Mice; Morphine; Motor Activity; Norepinephrine; Serotonin | 1972 |
The effects of drugs on serotonergic nerve terminals.
Topics: Animals; Brain; Catecholamines; Cerebellum; Histocytochemistry; Hydroxyindoleacetic Acid; Hydroxylation; Kinetics; Lysergic Acid Diethylamide; Microscopy, Electron; Monoamine Oxidase Inhibitors; Morphine; Nerve Endings; Norepinephrine; Pargyline; Probenecid; Rats; Serotonin; Synapses; Time Factors; Tryptophan | 1971 |
Reduced effect of morphine in midbrain raphe lesioned rats.
Topics: Animals; Brain Chemistry; Brain Diseases; Female; Hydroxyindoleacetic Acid; Mesencephalon; Morphine; Pain; Rats; Serotonin | 1970 |
Brain serotonin turnover in morphine tolerant and dependent mice.
Topics: Animals; Brain; Brain Chemistry; Chlorine; Drug Tolerance; Humans; Hydroxyindoleacetic Acid; Male; Mice; Morphinans; Morphine; Morphine Dependence; Narcotic Antagonists; Pargyline; Phenylalanine; Placebos; Serotonin; Sodium Chloride; Substance Withdrawal Syndrome | 1970 |
Increased serotonin turnover in the acutely morphine treated rat.
Topics: Animals; Brain; Hydroxyindoleacetic Acid; Male; Morphine; Organ Size; Pargyline; Probenecid; Rats; Serotonin; Time Factors | 1971 |
Changes in the metabolism of 3,4-dihydroxyphenylethylamine (dopamine) in the striatum of the mouse induced by drugs.
Topics: Anesthetics; Animals; Behavior, Animal; Brain; Dopamine; Drug Antagonism; Hydroxyindoleacetic Acid; Imipramine; In Vitro Techniques; Methylphenidate; Methyltyrosines; Mice; Mixed Function Oxygenases; Monoamine Oxidase; Morphine; Parasympatholytics; Parasympathomimetics; Pargyline; Phencyclidine; Phenylacetates; Pilocarpine; Probenecid; Reserpine; Tolazoline; Tranquilizing Agents; Tyrosine; Zoxazolamine | 1966 |
Chronic morphine administration decreases 5-hydroxytryptamine and 2-hydroxyindoleacetic acid content in the brain of rats.
Topics: Animals; Body Weight; Brain; Hydroxyindoleacetic Acid; Male; Morphine; Naloxone; Rats; Serotonin | 1980 |
Effect of acute administration of morphine on newly synthesized 5-hydroxytryptamine in spinal cord of the rat.
Topics: Animals; Brain; Hydroxyindoleacetic Acid; Kinetics; Male; Morphine; Naloxone; Organ Specificity; Rats; Serotonin; Spinal Cord; Tryptophan | 1980 |
Role of monoaminergic systems in morphine-induced respiratory depression.
Topics: Animals; Biogenic Amines; Brain Chemistry; Depression, Chemical; Hydroxyindoleacetic Acid; Male; Morphine; Norepinephrine; Rats; Respiration; Serotonin; Time Factors | 1981 |
Mapping, in the rat central nervous system, of morphine-induced changes in turnover of 5-hydroxytryptamine.
Topics: Animals; Central Nervous System; Endorphins; Hydroxyindoleacetic Acid; Male; Morphine; Naloxone; Neurons; Rats; Serotonin | 1981 |
The importance of 5-hydroxytryptamine turnover for the analgesic effect of morphine in the chicken.
Topics: Aging; Animals; Brain; Chickens; Hydroxyindoleacetic Acid; Male; Morphine; Nociceptors; Serotonin; Species Specificity; Thermosensing | 1981 |
[Pharmacological action of eptazocine (l-1,4-dimethyl-10-hydroxy-2,3,4,5,6,7-hexahydro-1,6-methano-1H-4-banzazonine). (II) Relationship between the analgesic action of eptazocine and brain 5-hydroxytryptamine (5-HT) (author's transl)].
Topics: Analgesics; Animals; Brain Chemistry; Cyclazocine; Hydroxyindoleacetic Acid; Mice; Mice, Inbred Strains; Morphine; Pentazocine; Rats; Rats, Inbred Strains; Serotonin | 1981 |
Involvement of 5-hydroxytryptamine in the analgesic action of pethidine and morphine in mice.
Topics: Analgesics; Animals; Body Temperature; Brain Chemistry; Fenclonine; Fenfluramine; Hydroxyindoleacetic Acid; Male; Meperidine; Mice; Morphine; Reaction Time; Serotonin; Tryptophan | 1982 |
Analgesia, development of tolerance, and 5-hydroxytryptamine turnover in the rat after cerebral and systemic administration of morphine.
Topics: Animals; Brain; Cerebral Aqueduct; Corpus Striatum; Drug Tolerance; Hydroxyindoleacetic Acid; Injections, Subcutaneous; Male; Medulla Oblongata; Morphine; Naloxone; Neurons; Nociceptors; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Spinal Cord | 1982 |
The implication of central serotonin in electro-acupuncture tolerance in the rat.
Topics: 5-Hydroxytryptophan; Acupuncture Therapy; Analgesia; Animals; Brain; Brain Chemistry; Drug Tolerance; Electric Stimulation; Female; Hydroxyindoleacetic Acid; Male; Morphine; Rats; Receptors, Serotonin; Serotonin | 1982 |
Direct correlation between level of morphine and its biochemical effect on monoamine systems in mouse brain. Evidence for involvement of dopaminergic neurons in the pharmacological action of acute morphine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Brain; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Kinetics; Male; Mice; Mice, Inbred ICR; Morphine; Norepinephrine; Serotonin | 1983 |
Mass fragmentographic analysis of monoamine metabolites in the spinal cord of rat after the administration of morphine.
Topics: Animals; Biogenic Amines; Dopamine; Gas Chromatography-Mass Spectrometry; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Morphine; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Spinal Cord | 1983 |
Presence of opiate receptors on striatal serotoninergic nerve terminals.
Topics: Animals; Corpus Striatum; Dopamine; Enkephalin, Methionine; Fenfluramine; Hydroxyindoleacetic Acid; Male; Morphine; Naloxone; Nerve Degeneration; Neurons; Rats; Rats, Inbred Strains; Receptors, Opioid; Serotonin | 1983 |
Muscimol injections in the nucleus raphé dorsalis block the antinociceptive effect of morphine in rats: apparent lack of 5-hydroxytryptamine involvement in muscimol's effect.
Topics: 5,7-Dihydroxytryptamine; Analgesics; Animals; Brain Chemistry; Hydroxyindoleacetic Acid; Injections; Male; Morphine; Muscimol; Oxazoles; Raphe Nuclei; Rats; Reaction Time; Serotonin; Time Factors | 1984 |
Changes in 5-HIAA and 5-HT levels in lumbar CSF following morphine administration to conscious dogs.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dogs; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Injections, Spinal; Morphine; Serotonin | 1984 |
Higher environmental temperature-induced increase in body temperature: involvement of serotonin in GABA mediated interaction of opioidergic system.
Topics: 5-Hydroxytryptophan; Animals; Atropine; Body Temperature; Endorphins; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hot Temperature; Hydroxyindoleacetic Acid; Male; Methysergide; Morphine; Naloxone; Physostigmine; Rats; Serotonin; Tryptophan | 1993 |
Effect of morphine on hypothalamic tyrosine hydroxylase mRNA levels in dopaminergic neurons and on preoptic DOPAC levels measured by microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Diencephalon; Dopamine; Hydroxyindoleacetic Acid; Hypothalamus; Injections, Subcutaneous; Microdialysis; Morphine; Neurons; Preoptic Area; Prolactin; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tyrosine 3-Monooxygenase | 1994 |
Increased extracellular serotonin in rat brain after systemic or intraraphe administration of morphine.
Topics: Animals; Brain; Corpus Striatum; Diencephalon; Extracellular Space; Hippocampus; Hydroxyindoleacetic Acid; Infusions, Parenteral; Injections, Subcutaneous; Male; Microinjections; Morphine; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Serotonin; Stereotaxic Techniques; Time Factors | 1994 |
Extracellular dopamine and its metabolites in the nucleus accumbens of Fischer and Lewis rats: basal levels and cocaine-induced changes.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Cocaine; Dopamine; Extracellular Space; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Morphine; Nucleus Accumbens; Rats; Rats, Inbred F344; Rats, Inbred Lew | 1995 |
Effects of intraventricular injection of morphine and beta-endorphin on serotonin release from the spinal cord in rats.
Topics: Animals; beta-Endorphin; Chromatography, High Pressure Liquid; Drug Tolerance; Hydroxyindoleacetic Acid; Injections, Intraventricular; Male; Morphine; Rats; Rats, Sprague-Dawley; Serotonin; Spinal Cord | 1994 |
Effects of tianeptine on 5-hydroxyindoles and on the morphine-induced increase in 5-HT metabolism at the medullary dorsal horn level as measured by in vivo voltammetry in freely moving rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Electrochemistry; Hydroxyindoleacetic Acid; Indoles; Male; Medulla Oblongata; Morphine; Naloxone; Rats; Rats, Sprague-Dawley; Serotonin; Spinal Cord; Thiazepines | 1993 |
Relationship between analgesia and extracellular morphine in brain and spinal cord in awake rats.
Topics: Analgesia; Animals; Behavior, Animal; Brain Chemistry; Consciousness; Dose-Response Relationship, Drug; Homovanillic Acid; Hydroxyindoleacetic Acid; Hypothalamus; Male; Microdialysis; Morphine; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Serotonin; Spinal Cord | 1995 |
The reduction of antinociceptive effect of morphine administered intraventricularly is correlated with the decrease of serotonin release from the spinal cord in streptozotocin-induced diabetic rats.
Topics: Analgesics, Opioid; Animals; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Hydroxyindoleacetic Acid; Injections, Intraventricular; Male; Morphine; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Serotonin; Spinal Cord | 1996 |
Monoamine metabolism in the locus coeruleus measured concurrently with behavior during opiate withdrawal: an in vivo microdialysis study in freely moving rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analgesics, Opioid; Animals; Behavior, Animal; Biogenic Monoamines; Hydroxyindoleacetic Acid; Locus Coeruleus; Male; Microdialysis; Monoamine Oxidase Inhibitors; Morphine; Motor Activity; Naltrexone; Narcotic Antagonists; Pargyline; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 1997 |
In vivo voltammetric studies of the effects of intrathecal morphine on noxious heat stimuli-induced serotonin release in the nucleus raphe magnus of anesthetized rats.
Topics: Animals; Electrochemistry; Hot Temperature; Hydroxyindoleacetic Acid; Injections, Spinal; Male; Morphine; Naloxone; Pain; Raphe Nuclei; Rats; Rats, Wistar; Reaction Time; Serotonin; Spinal Cord; Uric Acid | 1997 |
Effect of naloxone on morphine-induced changes in striatal dopamine metabolism and glutamate, ascorbic acid and uric acid release in freely moving rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analgesics, Opioid; Animals; Ascorbic Acid; Corpus Striatum; Dopamine; Glutamic Acid; Homovanillic Acid; Hydroxyindoleacetic Acid; Locomotion; Male; Microdialysis; Morphine; Naloxone; Narcotic Antagonists; Rats; Rats, Wistar; Substantia Nigra; Uric Acid | 1998 |
Morphine tolerance in arthritic rats and serotonergic system.
Topics: Analgesics, Opioid; Animals; Arthritis, Experimental; Chronic Disease; Drug Tolerance; Extremities; Hydroxyindoleacetic Acid; Male; Morphine; Neurotransmitter Agents; Norepinephrine; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Serotonin; Spinal Cord; Time Factors; Up-Regulation | 1999 |
The potentiation of analgesic activity of paracetamol plus morphine involves the serotonergic system in rat brain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Behavior, Animal; Brain; Drug Synergism; Hydroxyindoleacetic Acid; Male; Morphine; Naloxone; Narcotic Antagonists; Pain Measurement; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin | 1999 |
Modulations of spinal serotonin activity affect the development of morphine tolerance.
Topics: 5,7-Dihydroxytryptamine; Analgesics, Opioid; Animals; Drug Tolerance; Hydroxyindoleacetic Acid; Injections, Intravenous; Male; Morphine; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Serotonin; Serotonin Agents; Spinal Cord | 2001 |
Modulation of noradrenergic and serotonergic transmission by noxious stimuli and intrathecal morphine differs in the dorsal raphe nucleus of anesthetized rat: in vivo voltammetric studies.
Topics: Animals; Catechols; Electrophysiology; Hindlimb; Hot Temperature; Hydroxyindoleacetic Acid; Injections, Spinal; Male; Morphine; Norepinephrine; Oxidation-Reduction; Pain; Raphe Nuclei; Rats; Rats, Wistar; Serotonin; Synaptic Transmission | 2002 |
Increases in the release and metabolism of serotonin in nucleus parafascicularis thalami following systemically administered morphine in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesics, Opioid; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Electrochemistry; Extracellular Space; Hydroxyindoleacetic Acid; Intralaminar Thalamic Nuclei; Male; Microdialysis; Morphine; Rats; Rats, Long-Evans; Serotonin; Vocalization, Animal | 2002 |
Systemic morphine-induced release of serotonin in the rostroventral medulla is not mimicked by morphine microinjection into the periaqueductal gray.
Topics: Analgesics, Opioid; Animals; Drug Administration Routes; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Fentanyl; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Medulla Oblongata; Microdialysis; Microinjections; Morphine; Naloxone; Narcotic Antagonists; Pain Measurement; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Serotonin; Substance Withdrawal Syndrome; Wakefulness | 2003 |
Prenatal morphine exposure affects sympathoadrenal axis activity and serotonin metabolism in adult male rats both under basal conditions and after an ether inhalation stress.
Topics: Adrenocorticotropic Hormone; Animals; Brain; Corticosterone; Ether; Female; Hydroxyindoleacetic Acid; Hypothalamo-Hypophyseal System; Male; Morphine; Narcotics; Pituitary-Adrenal System; Pregnancy; Prenatal Exposure Delayed Effects; Rats; RNA, Messenger; Serotonin; Stress, Physiological; Sympathetic Nervous System | 2005 |
Mesolimbic dopamine drives the diurnal variation in opiate-induced feeding.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Circadian Rhythm; Dopamine; Eating; Hydroxyindoleacetic Acid; Male; Morphine; Narcotics; Nucleus Accumbens; Olfactory Pathways; Rats; Rats, Sprague-Dawley; Serotonin | 2005 |
Chronic nicotine modifies the effects of morphine on extracellular striatal dopamine and ventral tegmental GABA.
Topics: Animals; Brain; Dihydroxyphenylalanine; Dopamine; Extracellular Fluid; gamma-Aminobutyric Acid; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mice; Microdialysis; Morphine; Motor Activity; Narcotics; Neurotransmitter Agents; Nicotine; Nicotinic Agonists; Time | 2008 |
Cerebrolysin and morphine decrease glutathione and 5-hydroxyindole acetic acid levels in fasted rat brain.
Topics: Amino Acids; Animals; Antioxidants; Brain; Drug Interactions; Female; Glutathione; Hydroxyindoleacetic Acid; Hypoglycemia; Lipid Peroxidation; Morphine; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Thiobarbituric Acid Reactive Substances | 2009 |
Absence of morphine analgesia and its underlying descending serotonergic activation in an experimental mouse model of fibromyalgia.
Topics: Animals; Cold Temperature; Fibromyalgia; Hydroxyindoleacetic Acid; Injections; Male; Mice; Mice, Inbred C57BL; Morphine; Narcotics; Serotonin; Spinal Cord; Stress, Physiological | 2010 |
Effect of morphine and lacosamide on levels of dopamine and 5-HIAA in brain regions of rats with induced hypoglycemia.
Topics: Acetamides; Animals; Blood Glucose; Cerebellum; Dopamine; Female; Hydroxyindoleacetic Acid; Hypoglycemia; Insulin; Lacosamide; Lipid Peroxidation; Medulla Oblongata; Morphine; Rats; Rats, Wistar | 2014 |