hydroxyindoleacetic acid and kynurenine

hydroxyindoleacetic acid has been researched along with kynurenine in 102 studies

Research

Studies (102)

TimeframeStudies, this research(%)All Research%
pre-199047 (46.08)18.7374
1990's14 (13.73)18.2507
2000's7 (6.86)29.6817
2010's23 (22.55)24.3611
2020's11 (10.78)2.80

Authors

AuthorsStudies
Baker, HF; Cross, AJ; Crow, TJ; Glover, V; Joseph, MH; Killpack, WS; Lofthouse, R; Longden, A; Owen, F; Riley, GJ1
Shibata, Y1
Curtius, HC; Gitzelmann, R; Otten, A; Wegmann, H1
Baker, HF; Crow, TJ; Jospeh, MH; Riley, GJ; Risby, D1
Kimmig, J; Kreysel, HW; Meyerhoff, K1
Gál, EM; Sherman, AD; Young, RB1
Bloomfield, MR; Green, AR; Seed, M; Woods, HF1
Joseph, MH1
Hullin, RP1
Ridges, AP1
Kurbanov, Kh1
Clark, JA; Clark, MS; Palfreyman, ES; Palfreyman, MG1
Green, AR; Sourkes, TL; Young, SN1
Krishnaswamy, K; Raghuram, TC; Rao, SB1
Nishimoto, Y; Shibata, Y; Takeuchi, F; Tatsuma, Y1
Heyes, MP; Maize, JC; Quearry, B; Silver, RM; Sternberg, EM; Vionnet-Fuasset, M1
Bonkovsky, HL; Gerron, GG; Healey, JF; Lourie, AN1
Fathi, M; Mainetti, C; Saurat, JH1
Beams, RM; Critchley, MA; Hodson, HF; Iyer, R; Knowles, RG; Madge, DJ; Pogson, CI; Salter, M1
Bender, DA; Njagi, EN1
Demisch, L; Kaczmarczyk, P1
Heyes, MP; Quearry, BJ1
Milovanović, DD; Milovanović, L; Radulović, D; Stanković, B1
Kimbrough, TD; Llewellyn, GC; Weekley, LB1
Heyes, MP; Markey, SP; Quearry, BJ1
Chruściel, M1
Brune, GG; Brune, RM; Wiskemann, A1
Leklem, JE1
Chiancone, FM1
Mandell, AJ; Rubin, RT1
Allegri, G; Costa, C; De Antoni, A; Rubaltelli, FF1
Moon, RJ; Morris, KM1
Chen, NC; Gholson, RK1
Abul-Fadl, M; Hamza, S; Khalafallah, A; Khattab, M1
Frazer, A; Mendels, J; Pandey, GN1
Payne, IR; Walsh, EM; Whittenburg, EJ1
Lu, GH; Meyer, K; Payne, IR1
Curzon, G1
Curzon, G; Green, AR1
Bakri, M; Carlson, JR1
Knapp, A; Reding, R; Teichmann, W1
Brodan, V; Kuhn, E; Rysánek, K1
Dreux, C; Genefke, IK; Halter, D1
Curzon, G; Robinson, N; Theaker, P1
Lipton, R; Melicow, MM; Price, TD1
Crokaert, R; Geeraerts, F; Schimpfessel, L1
Eggert, A; Teichmann, W1
Gál, EM; Sherman, AD1
Anokhina, IP; Gamaleia, NB1
Aronson, JK; Curzon, G; Green, AR; Woods, HF1
Joseph, MH; Kennett, GA1
Gauthier, S; Joseph, MH; Young, SN1
Abe, T; Hamato, H; Takahashi, J; Takahashi, S; Tohgi, H2
Kawase, S; Matsuo, S; Mitsufuji, N; Nishimura, A; Sawada, T; Takeuchi, Y; Tominaga, M; Yamazoe, I1
Altemus, M; Demitrack, MA; Gold, PW; Heyes, MP; Pigott, TA1
Achilli, G; Banting, A; Banting, S; Le Bars, D; Weil-Fugazza, J1
Jirgensons, J; Jurika, E; Rudzite, V1
Pawlak, D; Takada, A; Takada, Y; Urano, T1
Gaynor, CM; Handley, SL1
Callaway, J; Halonen, P; Liesivuori, J; Pennanen, S; Räsänen, P; Sainio, EL; Tiihonen, J; Virkkunen, M1
Ackenheil, M; Ewert, T; Lossau, K; Neumeister, A; Offenbaecher, M; Praschak-Rieder, N; Schwarz, MJ; Stucki, G; Weisser, R; Willeit, M; Zach, J; Zacherl, M1
KNAPP, A1
BENSON, GD; HAEFFNER, LJ; KOWLESSAR, OD1
ABUL-FADL, MA; KHALAFALLAH, AS1
Ackenheil, M; Neumeister, A; Offenbaecher, M; Schwarz, MJ1
Kaasik, A; Vaarmann, A; Zharkovsky, A1
Bridel, MA; Christofides, J; Cowlard, R; Darlington, LG; Forrest, CM; Mackay, GM; Mitchell, S; Stone, TW1
Dougherty, GG; Kaddurah-Daouk, R; Keshavan, MS; Krishnan, RR; Matson, WR; McEvoy, J; Montrose, DM; Reddy, RD; Rozen, S; Yao, JK1
Fukushima, T; Sasaki, T; Toyo'oka, T; Yamashita, K1
Barone, PR; Belzung, C; Callebert, J; Laugeray, A; Launay, JM; Surget, A1
Chen, H; Gao, P; Luo, X; Ni, P; Xu, B; Zhan, Y; Zhao, J; Zhu, D1
Buurman, WA; Dekker, J; Jonkers, DM; Keszthelyi, D; Masclee, AA; Troost, FJ; van Donkelaar, EL1
Corona, AW; Dantzer, R; Godbout, JP; Huang, Y; Kelley, KW; Lawson, M; Norden, DM; O'Connor, JC; Skendelas, JP1
Baghai, TC; Bondy, B; Eser, D; Müller, N; Myint, AM; Nothdurfter, C; Rupprecht, R; Schüle, C; Schwarz, MJ; Zill, P1
Bezrukov, MV; Shilov, IuE1
Chugani, DC; Jyoti, A; Kannan, RM; Kannan, S; Lesniak, WG; Louissaint, N; Mishra, MK; Romero, R1
Ding, M; Fan, Z; Feng, C; Gao, J; Yang, X; Zhen, Q; Zhu, M1
Hennings, A; Rief, W; Riemer, S; Schwarz, MJ; Selberdinger, VB; Stapf, TM1
Bergink, V; Burgerhout, KM; Drexhage, HA; Hoogendijk, WJ; Kushner, SA; Myint, AM; Schütze, G; Schwarz, MJ; Veen, C1
Capi, M; Curto, M; Fazio, F; Giamberardino, MA; Lionetto, L; Martelletti, P; Negro, A; Nicoletti, F; Perugino, F; Simmaco, M1
Capi, M; Curto, M; Fazio, F; Giamberardino, MA; Lionetto, L; Martelletti, P; Negro, A; Nicoletti, F; Simmaco, M1
Challa, S; Madigubba, S; Panigrahi, M; Phanithi, PB; Talari, NK1
Benedetti, F; Bollettini, I; Colombo, C; Grillitsch, D; Locatelli, C; Mazza, E; Myint, AM; Poletti, S; Schüetze, G; Schwarz, M1
Boeira, SP; de Gomes, MG; Jesse, CR; Mattos, E; Silva, NC; Souza, LC; Viana, CE1
Cheng, J; Gao, X; Hou, X; Jin, H; Lv, J; Zheng, G1
Ding, L; Jiang, X; Jing, C; Liu, F; Pang, C; Yan, Q; Zhang, L1
Cui, T; Du, TT; Huang, D; Jiang, XH; Qiu, HM; Wang, NR1
Amore, M; Baldessarini, RJ; Berardelli, I; Curto, M; Erbuto, D; Forte, A; Girardi, P; Innamorati, M; Lionetto, L; Montebovi, F; Pompili, M; Serafini, G; Seretti, ME; Simmaco, M1
Baldessarini, RJ; Comparelli, A; Corigliano, V; Curto, M; Fazio, F; Ferracuti, S; Lionetto, L; Nicoletti, F; Simmaco, M1
Böhmová, A; Horáček, J; Kodym, P; Krsek, D; Mikoška, M; Syslová, K; Tejkalová, H; Vacek, L; Vondroušová, J1
Bédos, JP; Bruneel, F; Henry-Lagarrigue, M; Legriel, S; Soppelsa, F; Spreux-Varoquaux, O; Troché, G; Yehia, A1
Ahn, G; Harmon, DL; Klotz, JL; Valente, EEL1
Babyak, MA; Boyle, SH; Georgiades, A; Grichnik, K; Kaddurah-Daouk, R; Kuhn, CM; Matson, SA; Matson, WR; Mirjankar, N; Reavis, ZW; Sarangi, S; Siegler, IC; Stafford-Smith, M; Suarez, EC; Williams, RB1
Cai, H; Cao, T; Chen, Q; Jiao, S; Wang, L; Wu, X; Yang, C; Yang, D; Yang, P; Zeng, C; Zhang, S; Zhu, Z1
Dai, M; Huang, X; Jiang, Z; Kou, S; Li, X; Sun, L; Wang, Q1
Fathi, M; Hajibeygi, R; Jazi, K; Klegeris, A; McElhinney, A; Sayehmiri, F; Shool, S; Sodeifian, F; Tavasol, A; Tavirani, MR; Vakili, K; Yaghoobpoor, S1
de Rijke, YB; Griffioen, PH; Mirzaian, M; Steegers-Theunissen, RPM; van Rossem, L; van Schaik, RHN; van Zundert, SKM; Willemsen, SP1
Ageev, AA; Appolonova, SA; Belenkov, YN; Korobkova, EO; Kozhevnikova, MV; Krivova, AV; Moskaleva, NE; Privalova, EV; Shestakova, KM1
Blasiak, J; Chojnacki, C; Chojnacki, M; Fila, M; Gąsiorowska, A; Konrad, P; Popławski, T1
Błońska, A; Chojnacki, C; Chojnacki, M; Konrad, P; Podogrocki, M; Poplawski, T1
Blasiak, J; Błońska, A; Chojnacki, C; Chojnacki, J; Gąsiorowska, A; Konrad, P; Popławski, T; Zajdler, R1

Reviews

7 review(s) available for hydroxyindoleacetic acid and kynurenine

ArticleYear
Metabolism of indole amines in depression.
    Postgraduate medical journal, 1976, Volume: 52, Issue:3 suppl

    Topics: Animals; Brain; Depression; Fatty Acids, Nonesterified; Female; Humans; Hydrocortisone; Hydroxyindoleacetic Acid; Kynurenine; Male; Monoamine Oxidase Inhibitors; Rats; Serotonin; Tryptamines; Tryptophan

1976
Biogenic amines and depression. The potential value of biochemical parameters in the diagnosis and medication of affective disorders.
    Postgraduate medical journal, 1976, Volume: 52, Issue:3 suppl

    Topics: Antidepressive Agents; Biogenic Amines; Depression; Diagnosis, Differential; Humans; Hydroxyindoleacetic Acid; Kynurenine; Methoxyhydroxyphenylglycol; Norepinephrine; Normetanephrine; Serotonin; Vanilmandelic Acid

1976
Quantitative aspects of tryptophan metabolism in humans and other species: a review.
    The American journal of clinical nutrition, 1971, Volume: 24, Issue:6

    Topics: Age Factors; Amides; Animals; Carbon Isotopes; Cats; Dogs; Female; Glucuronates; Glycine; Hippurates; Humans; Hydroxyindoleacetic Acid; Indican; Kynurenic Acid; Kynurenine; Lysine; Male; Mice; Niacinamide; Nicotinic Acids; ortho-Aminobenzoates; Pyridines; Pyridones; Pyridoxine; Rats; Serotonin; Sex Factors; Species Specificity; Swine; Time Factors; Tryptophan; Xanthurenates

1971
Tryptophan pyrrolase--a biochemical factor in depressive illness?
    The British journal of psychiatry : the journal of mental science, 1969, Volume: 115, Issue:529

    Topics: Animals; Brain; Cats; Depression; Female; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; Pituitary-Adrenal System; Rats; Serotonin; Tryptophan; Tryptophan Oxygenase

1969
L-kynurenine: its synthesis and possible regulatory function in brain.
    Neurochemical research, 1980, Volume: 5, Issue:3

    Topics: Animals; Arylformamidase; Brain; Decarboxylation; Humans; Hydroxyindoleacetic Acid; Kinetics; Kynurenine; Kynurenine 3-Monooxygenase; Mixed Function Oxygenases; Oxygenases; Serotonin; Tryptophan; Tryptophan Oxygenase

1980
[Kynurenines in pathogenesis of endogenous psychiatric disorders].
    Vestnik Rossiiskoi akademii meditsinskikh nauk, 2013, Issue:1

    Topics: Humans; Hydroxyindoleacetic Acid; Kynurenine; Mental Disorders; Psychotic Disorders; Tryptophan; Xanthurenates

2013
Dynamic changes in metabolites of the kynurenine pathway in Alzheimer's disease, Parkinson's disease, and Huntington's disease: A systematic Review and meta-analysis.
    Frontiers in immunology, 2022, Volume: 13

    Topics: 3-Hydroxyanthranilic Acid; Adenosine; Alzheimer Disease; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; NAD; Niacinamide; Parkinson Disease; Tryptophan

2022

Trials

5 trial(s) available for hydroxyindoleacetic acid and kynurenine

ArticleYear
Metabolism of an oral tryptophan load. I: Effects of dose and pretreatment with tryptophan.
    British journal of clinical pharmacology, 1980, Volume: 10, Issue:6

    Topics: Administration, Oral; Adult; Dose-Response Relationship, Drug; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; Protein Binding; Tryptophan

1980
Free L-tryptophan plasma levels in antisocial violent offenders.
    Psychopharmacology, 2001, Volume: 157, Issue:4

    Topics: Adult; Amino Acids; Brain Chemistry; Crime; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; Middle Aged; Serotonin; Tryptophan; Violence

2001
Kynurenine metabolites and inflammation markers in depressed patients treated with fluoxetine or counselling.
    Clinical and experimental pharmacology & physiology, 2009, Volume: 36, Issue:4

    Topics: Adult; Antidepressive Agents; Biomarkers; Counseling; Depression; Drug Therapy, Combination; Female; Fluoxetine; Humans; Hydroxyindoleacetic Acid; Inflammation; Kynurenine; Male; Middle Aged; Psychotherapy; Serotonin; Triiodothyronine

2009
Does acute tryptophan depletion affect peripheral serotonin metabolism in the intestine?
    The American journal of clinical nutrition, 2012, Volume: 95, Issue:3

    Topics: Adult; Central Nervous System; Double-Blind Method; Female; Humans; Hydroxyindoleacetic Acid; Intestinal Mucosa; Intestines; Kynurenic Acid; Kynurenine; Male; Serotonin; Tryptophan; Young Adult

2012
Pattern of postruminal administration of l-tryptophan affects blood serotonin in cattle.
    Domestic animal endocrinology, 2021, Volume: 74

    Topics: Animals; Cattle; Drug Administration Routes; Hydroxyindoleacetic Acid; Kynurenine; Male; Serotonin; Tryptophan

2021

Other Studies

90 other study(ies) available for hydroxyindoleacetic acid and kynurenine

ArticleYear
Monoamine mechanisms in chronic schizophrenia: post-mortem neurochemical findings.
    The British journal of psychiatry : the journal of mental science, 1979, Volume: 134

    Topics: Aged; Brain Chemistry; Catechol O-Methyltransferase; Chronic Disease; Dopamine; Dopamine beta-Hydroxylase; Female; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; Monoamine Oxidase; Norepinephrine; Phenylacetates; Schizophrenia; Serotonin; Tryptophan; Tyrosine 3-Monooxygenase

1979
On the regulation of tryptophan metabolism "via" kynurenine.
    Acta vitaminologica et enzymologica, 1978, Volume: 32, Issue:5-6

    Topics: Animals; Hydrogen-Ion Concentration; Hydroxyindoleacetic Acid; Hydroxylation; Kynurenine; Mixed Function Oxygenases; NAD; NADP; Nicotinic Acids; ortho-Aminobenzoates; Phenylalanine; Rats; Serotonin; Solubility; Tryptophan; Xanthurenates

1978
Nutritive value of N-acetyl-L-tryptophan in man.
    Helvetica paediatrica acta, 1979, Volume: 34, Issue:5

    Topics: Blood Proteins; Deuterium; Female; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; Nutritive Value; Tryptophan

1979
Brain tryptophan metabolism in schizophrenia: a post mortem study of metabolites of the serotonin and kynurenine pathways in schizophrenic and control subjects.
    Psychopharmacology, 1979, Apr-25, Volume: 62, Issue:3

    Topics: Aged; Aging; Brain; Female; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; Middle Aged; Myocardial Infarction; Postmortem Changes; Schizophrenia; Serotonin; Sex Factors; Tryptophan

1979
[Tryptophan-load in progressive scleroderma (author's transl)].
    Klinische Wochenschrift, 1976, Sep-15, Volume: 54, Issue:18

    Topics: 3-Hydroxyanthranilic Acid; Female; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Kynurenine; Male; Niacinamide; Scleroderma, Systemic; Serotonin; Skin; Tryptamines; Tryptophan; Xanthurenates

1976
Tryptophan loading: consequent effects on the synthesis of kynurenine and 5-hydroxyindoles in rat brain.
    Journal of neurochemistry, 1978, Volume: 31, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Brain; Fasting; Hydroxyindoleacetic Acid; Kynurenine; Male; Rats; Serotonin; Tryptophan

1978
Metabolism of an oral tryptophan load by women and evidence against the induction of tryptophan pyrrolase by oral contraceptives.
    British journal of clinical pharmacology, 1978, Volume: 5, Issue:3

    Topics: Adult; Contraceptives, Oral; Enzyme Induction; Female; Half-Life; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Kynurenine; Time Factors; Tryptophan; Tryptophan Oxygenase

1978
Brain tryptophan metabolism on the 5-hydroxytryptamine and kynurenine pathways in a strain of rats with a deficiency in platelet 5-HT.
    British journal of pharmacology, 1978, Volume: 63, Issue:3

    Topics: Animals; Blood Platelets; Brain; Hydroxyindoleacetic Acid; Kynurenine; Male; Pargyline; Rats; Reserpine; Serotonin; Tryptophan

1978
[Relationship between tryptophan metabolism and the state of melaninogensis].
    Biulleten' eksperimental'noi biologii i meditsiny, 1976, Volume: 82, Issue:12

    Topics: Animals; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Liver; Melanins; ortho-Aminobenzoates; Rabbits; Tryptophan; Tryptophan Oxygenase; Xanthurenates

1976
The effect of tryptophan and a tryptophan/5-hydroxytryptophan combination on indoles in the brains of rats fed a tryptophan deficient diet.
    Psychopharmacologia, 1975, Dec-31, Volume: 45, Issue:2

    Topics: 3-Hydroxyanthranilic Acid; 5-Hydroxytryptophan; Animals; Brain; Depression; Diet; Drug Synergism; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; Rats; Serotonin; Tryptophan; Tryptophan Oxygenase

1975
Liver and brain tryptophan metabolism following hydrocortisone administration to rats and gerbils.
    British journal of pharmacology, 1975, Volume: 53, Issue:2

    Topics: Animals; Brain; Gerbillinae; Hydrocortisone; Hydroxyindoleacetic Acid; Kynurenine; Liver; Male; Rats; Serotonin; Tryptophan; Tryptophan Oxygenase

1975
Role of vitamin B6 on leucine-induced metabolic changes.
    Nutrition and metabolism, 1975, Volume: 18, Issue:5-6

    Topics: Animals; Brain; Diet; Female; Hydrolases; Hydroxyindoleacetic Acid; Isoleucine; Kynurenine; Leucine; Liver; Male; Nicotinic Acids; Organ Size; Pyridines; Pyridoxine; Quinolinic Acids; Rats; Serotonin; Tryptophan Oxygenase

1975
Tryptophan metabolism in various nutritive conditions.
    Acta vitaminologica et enzymologica, 1975, Volume: 29, Issue:1-6

    Topics: Animals; Diet; Epinephrine; Hydroxyindoleacetic Acid; Kynurenine; Nicotinic Acids; ortho-Aminobenzoates; Phenylalanine; Pyridoxine; Quinolines; Rats; Serotonin; Starvation; Tryptophan; Xanthurenates

1975
Scleroderma, fasciitis, and eosinophilia associated with the ingestion of tryptophan.
    The New England journal of medicine, 1990, Mar-29, Volume: 322, Issue:13

    Topics: Adult; Aged; Eosinophilia; Fascia; Fasciitis; Female; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; Middle Aged; Muscles; Scleroderma, Systemic; Skin; Tryptophan

1990
Intravenous heme-albumin in acute intermittent porphyria: evidence for repletion of hepatic hemoproteins and regulatory heme pools.
    The American journal of gastroenterology, 1991, Volume: 86, Issue:8

    Topics: Acute Disease; Adult; Aminolevulinic Acid; Analysis of Variance; Cytochrome P-450 Enzyme System; Female; Hemin; Humans; Hydroxyindoleacetic Acid; Infusions, Intravenous; Kynurenine; Liver; Middle Aged; Porphobilinogen; Porphyrias; Porphyrins; Serum Albumin; Tryptophan

1991
L-tryptophan-induced eosinophilia-myalgia syndrome. II. Partial correction of abnormal tryptophan metabolism by pyridoxine.
    Dermatologica, 1991, Volume: 183, Issue:1

    Topics: Adult; Eosinophilia-Myalgia Syndrome; Female; Humans; Hydroxyindoleacetic Acid; Kynurenine; Middle Aged; Pyridoxine; Serotonin; Tryptophan

1991
Effects of tryptophan 2,3-dioxygenase inhibitors in the rat.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: Animals; Anxiety; Brain; Enzyme Inhibitors; Hydroxyindoleacetic Acid; Kynurenine; Liver; Organic Chemicals; Rats; Serotonin; Tryptophan; Tryptophan Oxygenase

1991
Tryptophan metabolism in mice infected with Schistosoma mansoni.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: Animals; Cells, Cultured; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Liver; Male; Mice; Niacinamide; Schistosomiasis mansoni; Serotonin; Tryptophan; Xanthurenates

1991
Tryptophan metabolism in healthy subjects: influence of pyridoxine after single or repeated administrations.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: Adult; Biological Transport; Female; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; Middle Aged; Pyridoxine; Serotonin; Tryptophan

1991
Increased L-tryptophan, 5-hydroxyindoleacetic acid, 3-hydroxykynurenine and quinolinic acid concentrations in cerebral cortex following systemic endotoxin administration.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: Animals; Brain Chemistry; Cerebral Cortex; Endotoxins; Hydroxyindoleacetic Acid; Kynurenine; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Quinolinic Acid; Quinolinic Acids; Serotonin; Stimulation, Chemical; Tryptophan

1991
Tryptophan and its metabolites in a family with Hartnup disease.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: Adolescent; Adult; Child; Female; Hartnup Disease; Humans; Hydroxyindoleacetic Acid; Intestinal Absorption; Kidney Tubules, Proximal; Kynurenine; Male; Tryptophan; Xanthurenates

1991
Disturbances in tryptophan metabolism in rats following chronic dietary aflatoxin treatment.
    Drug and chemical toxicology, 1985, Volume: 8, Issue:3

    Topics: Aflatoxins; Animals; Bile Ducts; Brain Chemistry; Cell Division; Diet; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Liver; Male; Precancerous Conditions; Rats; Serotonin; Tryptophan; Tryptophan Oxygenase

1985
Systemic endotoxin increases L-tryptophan, 5-hydroxyindoleacetic acid, 3-hydroxykynurenine and quinolinic acid content of mouse cerebral cortex.
    Brain research, 1989, Jul-03, Volume: 491, Issue:1

    Topics: Animals; Cerebral Cortex; Endotoxins; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Kynurenine; Mice; Mice, Inbred C57BL; Pyridines; Quinolinic Acid; Quinolinic Acids; Salmonella; Time Factors; Tryptophan

1989
Changes resembling lupus erythematosus after prolonged treatment with Ro-4-4602, a potent inhibitor of 5-HTP-carboxyliase, in white rats.
    European journal of pharmacology, 1969, Volume: 8, Issue:2

    Topics: 5-Hydroxytryptophan; Aminobenzoates; Animals; Carboxy-Lyases; Cholesterol; Creatinine; Female; Hydrazines; Hydroxyindoleacetic Acid; Kidney; Kynurenine; Liver; Lupus Erythematosus, Systemic; Male; Neutrophils; Proline; Rats; Spleen; Tryptophan; Vanilmandelic Acid

1969
[Tryptophan metabolism in patients with pellagra].
    Archiv fur dermatologische Forschung, 1970, Volume: 240, Issue:1

    Topics: Acetaminophen; Administration, Oral; Adult; Aged; Child, Preschool; Female; Hartnup Disease; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Kynurenine; Middle Aged; Niacinamide; Pellagra; Tryptamines; Tryptophan

1970
[Functional exploration at various levels of the tryptophan--nicotinic acid metabolic line].
    Acta vitaminologica et enzymologica, 1972, Volume: 26, Issue:3

    Topics: Diabetes Mellitus; Down Syndrome; Female; Humans; Hydroxyindoleacetic Acid; Hydroxylation; Kynurenine; Male; Nicotinic Acids; ortho-Aminobenzoates; Oxidation-Reduction; Pregnancy; Serotonin; Tryptophan; Vitamin B 6 Deficiency

1972
ACTH induced changes in tryptophan turnover along induceable pathways in man.
    Life sciences, 1966, Volume: 5, Issue:13

    Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Carbon Isotopes; Glycine; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Kynurenine; Male; Tryptophan

1966
Urinary excretion of tryptophan metabolites during phototherapy.
    The Journal of pediatrics, 1974, Volume: 85, Issue:6

    Topics: Aminohippuric Acids; Humans; Hydroxyindoleacetic Acid; Hyperbilirubinemia; Infant, Newborn; Infant, Newborn, Diseases; Kynurenic Acid; Kynurenine; ortho-Aminobenzoates; Photochemistry; Phototherapy; Serotonin; Tryptophan; Xanthurenates

1974
Microanalysis of tryptophan metabolites in mice.
    Analytical biochemistry, 1974, Volume: 61, Issue:2

    Topics: Animals; Autoradiography; Carbon Radioisotopes; Chromatography, DEAE-Cellulose; Chromatography, Thin Layer; Creatinine; Evaluation Studies as Topic; Female; Fluorescence; Glucuronates; Hydroxyindoleacetic Acid; Indicators and Reagents; Kynurenine; Methods; Mice; Microchemistry; Serotonin; Sulfuric Acids; Tryptophan

1974
An improved column chromatographic method for isolation of tryptophan metabolites.
    Analytical biochemistry, 1972, Volume: 47, Issue:1

    Topics: 5-Hydroxytryptophan; Aldehydes; Amides; Animals; Chromatography, DEAE-Cellulose; Colorimetry; Hydroxyindoleacetic Acid; Indoleacetic Acids; Kynurenic Acid; Kynurenine; Male; Methods; Nitriles; Rats; Serotonin; Spectrometry, Fluorescence; Tryptamines; Tryptophan; Urea; Vitamin B 6 Deficiency; Xanthurenates

1972
Studies on the urinary excretion of certain tryptophan metabolites in diabetics.
    The Journal of the Egyptian Medical Association, 1972, Volume: 55, Issue:7

    Topics: Adolescent; Adult; Amino Acids; Diabetes Mellitus; Female; Humans; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Male; Middle Aged; Nitrogen; ortho-Aminobenzoates; Phenylbutyrates; Tryptophan; Xanthurenates

1972
Metabolism of tryptophan in depressive disease.
    Archives of general psychiatry, 1973, Volume: 29, Issue:4

    Topics: Adult; Bipolar Disorder; Depression; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; Metabolic Clearance Rate; Middle Aged; Personality Disorders; Pyridoxine; Tryptamines; Tryptophan

1973
Relationship of dietary tryptophan and niacin to tryptophan metabolism in schizophrenics and nonschizophrenics.
    The American journal of clinical nutrition, 1974, Volume: 27, Issue:6

    Topics: Acetates; Aminohippuric Acids; Diet; Female; Humans; Hydroxyindoleacetic Acid; Indican; Indoles; Kynurenic Acid; Kynurenine; Male; Nicotinic Acids; ortho-Aminobenzoates; Schizophrenia; Tryptophan; Tryptophan Hydroxylase; Tryptophan Oxygenase; Vitamin B 6 Deficiency; Xanthurenates

1974
Relationship of dietary tryptophan and niacin to tryptophan metabolism in alcoholics and nonalcoholics.
    The American journal of clinical nutrition, 1974, Volume: 27, Issue:6

    Topics: Acetates; Alcoholism; Aminohippuric Acids; Diet; Dietary Proteins; Female; Humans; Hydroxyindoleacetic Acid; Indican; Indoleacetic Acids; Kynurenic Acid; Kynurenine; Male; Nicotinic Acids; ortho-Aminobenzoates; Tryptophan; Xanthurenates

1974
Regional and subcellular changes in the concentration of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in the rat brain caused by hydrocortisone, DL- -methyl-tryptophan l-kynurenine and immobilization.
    British journal of pharmacology, 1971, Volume: 43, Issue:1

    Topics: Animals; Basal Ganglia; Brain; Brain Chemistry; Cerebellum; Cerebral Cortex; Hydrocortisone; Hydroxyindoleacetic Acid; Hypothalamus; Immobilization; Injections, Intraperitoneal; Kynurenine; Medulla Oblongata; Mesencephalon; Neurons; Pons; Rats; Serotonin

1971
Chromatographic separation of tryptophan metabolites.
    Analytical biochemistry, 1970, Volume: 34

    Topics: 5-Hydroxytryptophan; Chromatography, Gel; Chromatography, Ion Exchange; Fluorometry; Hydrogen-Ion Concentration; Hydroxyindoleacetic Acid; Indoleacetic Acids; Indoles; Kynurenic Acid; Kynurenine; Methods; Methylcellulose; Picolinic Acids; Pyridines; Serotonin; Spectrophotometry; Tryptamines; Tryptophan; Ultraviolet Rays; Xanthurenates

1970
[5-hydroxyindoleacetic acid excretion in dumping syndrome].
    Zentralblatt fur Chirurgie, 1969, Jul-05, Volume: 94, Issue:27

    Topics: Dumping Syndrome; Female; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; Middle Aged; Xanthurenates

1969
Alterations of tryptophan metabolism induced by sleep deprivation.
    Experientia, 1968, Sep-15, Volume: 24, Issue:9

    Topics: Adult; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Kynurenine; ortho-Aminobenzoates; Sleep Deprivation; Tryptophan; Xanthurenates

1968
[Effects of cortisol on the urinary elimination of hydroxyindoles and kynurenine].
    Clinica chimica acta; international journal of clinical chemistry, 1969, Volume: 24, Issue:2

    Topics: 17-Hydroxycorticosteroids; Adult; Depression, Chemical; Female; Fluorometry; Humans; Hydrocortisone; Hydroxyindoleacetic Acid; Kynurenine; Male; Serotonin; Stimulation, Chemical; Time Factors; Tryptophan

1969
Excretion of tryptophan metabolites in Friedreich's ataxia.
    Journal of clinical pathology, 1965, Volume: 18, Issue:6

    Topics: Friedreich Ataxia; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Kynurenine; Tryptophan; Urine

1965
The degradation of tryptophan during paper chromatography with observations on some metabolites of tryptophan.
    Journal of chromatography, 1967, Volume: 26, Issue:2

    Topics: Autoradiography; Carbon Isotopes; Chromatography, Paper; Humans; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; ortho-Aminobenzoates; Tryptophan; Ultraviolet Rays; Xanthurenates

1967
The stability of tryptophan metabolites prior to urine analysis.
    Clinica chimica acta; international journal of clinical chemistry, 1980, Mar-28, Volume: 102, Issue:2-3

    Topics: 5-Hydroxytryptophan; Animals; Chromatography, High Pressure Liquid; Cold Temperature; Drug Stability; Humans; Hydrogen-Ion Concentration; Hydroxyindoleacetic Acid; Indoleacetic Acids; Kynurenic Acid; Kynurenine; Rats; Serotonin; Tryptophan

1980
[Serotonin and dumping syndrome (author's transl)].
    Leber, Magen, Darm, 1980, Volume: 10, Issue:1

    Topics: Dumping Syndrome; Glucose Tolerance Test; Humans; Hydroxyindoleacetic Acid; Kynurenine; Portal Vein; Serotonin; Xanthurenates

1980
[Current biochemical conceptions of mental diseases. II. Role of changes in the biogenic amine system in the pathogenesis of affective disorders].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1980, Volume: 80, Issue:6

    Topics: 3-Methoxy-4-hydroxyphenylethanol; Affective Disorders, Psychotic; Antidepressive Agents, Tricyclic; Biogenic Amines; Bipolar Disorder; Brain; Catechol O-Methyltransferase; Cyclic AMP; Depression; Dopamine; Dopamine beta-Hydroxylase; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Kynurenine; Monoamine Oxidase Inhibitors; Norepinephrine; Receptors, Dopamine; Reserpine; Serotonin; Tryptophan

1980
The functional importance of increased brain tryptophan in the serotonergic response to restraint stress.
    Neuropharmacology, 1981, Volume: 20, Issue:1

    Topics: Animals; Brain; Corticosterone; Hydroxyindoleacetic Acid; Kynurenine; Male; Rats; Serotonin; Stress, Physiological; Tryptophan; Valine

1981
Studies on kynurenine in human cerebrospinal fluid: lowered levels in epilepsy.
    Journal of neural transmission, 1983, Volume: 58, Issue:3-4

    Topics: Adolescent; Adult; Aged; Amino Acids; Anticonvulsants; Epilepsy; Epilepsy, Temporal Lobe; Humans; Hydroxyindoleacetic Acid; Kynurenine; Middle Aged; Tryptophan

1983
Alterations in the concentration of serotonergic and dopaminergic substances in the cerebrospinal fluid of patients with Parkinson's disease, and their changes after L-dopa administration.
    Neuroscience letters, 1993, Sep-03, Volume: 159, Issue:1-2

    Topics: Aged; Dopamine; Humans; Hydroxyindoleacetic Acid; Kynurenine; Levodopa; Middle Aged; Parkinson Disease; Psychometrics; Serotonin

1993
Thyrotropin-releasing hormone in treatment of intractable epilepsy: neurochemical analysis of CSF monoamine metabolites.
    Pediatric neurology, 1995, Volume: 12, Issue:2

    Topics: Child; Child, Preschool; Electroencephalography; Epilepsy; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Kynurenine; Male; Methoxyhydroxyphenylglycol; Neurotransmitter Agents; Spasms, Infantile; Thyrotropin-Releasing Hormone; Treatment Outcome

1995
Cerebrospinal fluid levels of kynurenine pathway metabolites in patients with eating disorders: relation to clinical and biochemical variable.
    Biological psychiatry, 1995, Apr-15, Volume: 37, Issue:8

    Topics: Adolescent; Adult; Anorexia Nervosa; Body Weight; Brain; Bulimia; Female; Humans; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Quinolinic Acid; Thinness; Tryptophan

1995
Concentrations of serotonin and its related substances in the cerebrospinal fluid of parkinsonian patients and their relations to the severity of symptoms.
    Neuroscience letters, 1993, Feb-05, Volume: 150, Issue:1

    Topics: 5-Hydroxytryptophan; Humans; Hydroxyindoleacetic Acid; Kynurenine; Middle Aged; Parkinson Disease; Reference Values; Serotonin; Tryptophan

1993
Tyrosine and tryptophan derivatives in pig lumbar cerebrospinal fluid. Effects of subchronic administration of dopa associated with benserazide.
    Advances in experimental medicine and biology, 1996, Volume: 398

    Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Oral; Animals; Benserazide; Drug Interactions; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Kynurenine; Levodopa; Male; Methoxyhydroxyphenylglycol; Normetanephrine; Swine; Tryptamines; Tryptophan; Tyrosine

1996
Changes in membrane fluidity induced by tryptophan and its metabolites.
    Advances in experimental medicine and biology, 1999, Volume: 467

    Topics: Animals; Cell Cycle; Cell Membrane; Cholesterol; Fatty Acids; Hydroxyindoleacetic Acid; Kinetics; Kynurenic Acid; Kynurenine; Liver; Male; Membrane Fluidity; Membrane Lipids; Phospholipids; Picolinic Acids; Rats; Rats, Wistar; Tryptophan; Xanthurenates

1999
Serotonergic and kynurenic pathways in rats exposed to foot shock.
    Brain research bulletin, 2000, Volume: 52, Issue:3

    Topics: Animals; Brain; Brain Chemistry; Electroshock; Hydroxyindoleacetic Acid; Kidney; Kynurenic Acid; Kynurenine; Liver; Male; Rats; Rats, Wistar; Serotonin; Stress, Physiological; Tryptophan

2000
Effects of nicotine on head-shakes and tryptophan metabolites.
    Psychopharmacology, 2001, Volume: 153, Issue:3

    Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Head Movements; Hydroxyindoleacetic Acid; Indophenol; Kynurenine; Male; Mice; Nicotine; Nicotinic Agonists; Pyridines; Serotonin; Serotonin Receptor Agonists; Tics; Tryptophan

2001
Evidence for an altered tryptophan metabolism in fibromyalgia.
    Neurobiology of disease, 2002, Volume: 11, Issue:3

    Topics: Adult; Case-Control Studies; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Female; Fibromyalgia; Humans; Hydroxyindoleacetic Acid; Interleukin-6; Kynurenine; Middle Aged; Pain; Serotonin; Tryptophan

2002
[Tryptophan loading and vitamin B6 deficiency. I. Excretion of xanthurenic acid, kynurenine, trigonelline amide, and 5-hydroxyindoleacetic acid in various diseases].
    Das Deutsche Gesundheitswesen, 1961, May-25, Volume: 16

    Topics: Alkaloids; Amides; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Kynurenic Acid; Kynurenine; Niacin; Nicotinic Acids; Tryptophan; Vitamin B 6 Deficiency; Xanthurenates

1961
ABNORMAL TRYPTOPHAN METABOLISM IN PATIENTS WITH ADULT CELIAC DISEASE, WITH EVIDENCE FOR DEFICIENCY OF VITAMIN B6.
    The Journal of clinical investigation, 1964, Volume: 43

    Topics: Adult; Biochemical Phenomena; Biochemistry; Celiac Disease; Dietary Proteins; Glutens; Humans; Hydroxyindoleacetic Acid; Indican; Indoleacetic Acids; Kynurenic Acid; Kynurenine; Proteins; Tetracycline; Tryptophan; Urine; Vitamin B 6; Vitamin B 6 Deficiency; Xanthurenates

1964
STUDIES ON THE URINARY EXCRETION OF CERTAIN TRYPTOPHAN METABOLITES BEFORE AND AFTER TRYPTOPHAN LOADING DOSE IN BILHARZIASIS, BILHARZIAL BLADDER CANCER AND CERTAIN OTHER TYPES OF MALIGNANCIES IN EGYPT.
    British journal of cancer, 1964, Volume: 13

    Topics: Amino Acids; Egypt; Epidemiology; Fluids and Secretions; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Kynurenic Acid; Kynurenine; Neoplasms; ortho-Aminobenzoates; Schistosomiasis; Tryptophan; Urinary Bladder Neoplasms; Urine; Xanthurenates

1964
Experimental evaluation of an altered tryptophan metabolism in fibromyalgia.
    Advances in experimental medicine and biology, 2003, Volume: 527

    Topics: Adult; Case-Control Studies; Cross-Over Studies; Double-Blind Method; Female; Fibromyalgia; Humans; Hydroxyindoleacetic Acid; Interleukin-6; Kynurenine; Middle Aged; Pain; Serotonin; Tryptophan

2003
Altered tryptophan metabolism in the brain of cystatin B-deficient mice: a model system for progressive myoclonus epilepsy.
    Epilepsia, 2006, Volume: 47, Issue:10

    Topics: Animals; Brain; Cerebellum; Cerebral Cortex; Chromatography, High Pressure Liquid; Cystatin B; Cystatins; Disease Models, Animal; Female; Hydroxyindoleacetic Acid; Kynurenine; Male; Mice; Mutation; Phenotype; Serotonin; Synaptic Transmission; Tryptophan; Unverricht-Lundborg Syndrome

2006
Altered interactions of tryptophan metabolites in first-episode neuroleptic-naive patients with schizophrenia.
    Molecular psychiatry, 2010, Volume: 15, Issue:9

    Topics: Adolescent; Adult; Antipsychotic Agents; Female; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; Melatonin; Oxidative Stress; Schizophrenia; Serotonin; Tryptophan; Young Adult

2010
Stereoselective effect of kynurenine enantiomers on the excretion of serotonin and its metabolite in rat urine.
    Chirality, 2010, Volume: 22, Issue:2

    Topics: Animals; Carboxylic Acids; Chromatography, High Pressure Liquid; Dopamine; Hydroxyindoleacetic Acid; Indoles; Kynurenine; Male; Models, Chemical; Rats; Rats, Sprague-Dawley; Rats, Wistar; Serotonin; Spectrometry, Fluorescence; Stereoisomerism

2010
Peripheral and cerebral metabolic abnormalities of the tryptophan-kynurenine pathway in a murine model of major depression.
    Behavioural brain research, 2010, Jun-26, Volume: 210, Issue:1

    Topics: Animals; Brain; Chronic Disease; Depressive Disorder, Major; Disease Models, Animal; Hydroxyindoleacetic Acid; Kynurenine; Lung; Male; Metabolic Networks and Pathways; Mice; Mice, Inbred BALB C; Serotonin; Stress, Psychological; Tryptophan

2010
Simultaneous determination of urinary tryptophan, tryptophan-related metabolites and creatinine by high performance liquid chromatography with ultraviolet and fluorimetric detection.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, Sep-15, Volume: 879, Issue:26

    Topics: Adult; Chromatography, High Pressure Liquid; Creatinine; Drug Stability; Female; Humans; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Linear Models; Male; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tryptophan

2011
Indoleamine 2,3-dioxygenase inhibition attenuates lipopolysaccharide induced persistent microglial activation and depressive-like complications in fractalkine receptor (CX(3)CR1)-deficient mice.
    Brain, behavior, and immunity, 2013, Volume: 31

    Topics: Animals; Behavior, Animal; Brain; CX3C Chemokine Receptor 1; Depression; Hydroxyindoleacetic Acid; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Lipopolysaccharides; Mice; Microglia; Motor Activity; Receptors, Cytokine; Receptors, HIV; Serotonin; Tryptophan

2013
Tryptophan metabolism and immunogenetics in major depression: a role for interferon-γ gene.
    Brain, behavior, and immunity, 2013, Volume: 31

    Topics: Adult; Aged; Depressive Disorder, Major; Female; Humans; Hydroxyindoleacetic Acid; Immunogenetics; Interferon-gamma; Kynurenine; Male; Middle Aged; Polymorphism, Genetic; Serotonin; Tryptophan

2013
Concurrent quantification of tryptophan and its major metabolites.
    Analytical biochemistry, 2013, Dec-15, Volume: 443, Issue:2

    Topics: Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Limit of Detection; Rabbits; Serotonin; Tandem Mass Spectrometry; Tryptophan

2013
[Simultaneous determination of tryptophan and its metabolites in plasma by high performance liquid chromatography with on-column derivatization].
    Se pu = Chinese journal of chromatography, 2013, Volume: 31, Issue:6

    Topics: Acetonitriles; Chromatography, High Pressure Liquid; Female; Fluorescence; Humans; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Limit of Detection; Pregnancy; Reproducibility of Results; Tryptophan; Tyrosine; Zinc Acetate

2013
Exercise affects symptom severity but not biological measures in depression and somatization - results on IL-6, neopterin, tryptophan, kynurenine and 5-HIAA.
    Psychiatry research, 2013, Dec-30, Volume: 210, Issue:3

    Topics: Adult; Case-Control Studies; Depression; Exercise; Female; Humans; Hydroxyindoleacetic Acid; Interleukin-6; Kynurenine; Male; Middle Aged; Neopterin; Severity of Illness Index; Somatoform Disorders; Tryptophan

2013
Tryptophan pathway alterations in the postpartum period and in acute postpartum psychosis and depression.
    Journal of affective disorders, 2016, Jan-01, Volume: 189

    Topics: Adult; Depression, Postpartum; Female; Humans; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Postpartum Period; Psychotic Disorders; Puerperal Disorders; Tandem Mass Spectrometry; Tryptophan; Young Adult

2016
Altered serum levels of kynurenine metabolites in patients affected by cluster headache.
    The journal of headache and pain, 2015, Volume: 17

    Topics: Adult; Cluster Headache; Female; Humans; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Male; Middle Aged; ortho-Aminobenzoates; Quinolinic Acid; Tryptophan; Xanthurenates

2015
Altered kynurenine pathway metabolites in serum of chronic migraine patients.
    The journal of headache and pain, 2015, Volume: 17

    Topics: Adult; Female; Humans; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Male; Middle Aged; Migraine Disorders; ortho-Aminobenzoates; Quinolinic Acid; Tandem Mass Spectrometry; Tryptophan; Xanthurenates

2015
Altered tryptophan metabolism in human meningioma.
    Journal of neuro-oncology, 2016, Volume: 130, Issue:1

    Topics: Analysis of Variance; Autopsy; Chromatography, High Pressure Liquid; Female; Humans; Hydroxyindoleacetic Acid; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Male; Meningeal Neoplasms; Meningioma; Nitric Oxide; Nitric Oxide Synthase Type II; RNA, Messenger; Serotonin; Tryptophan

2016
Kynurenine pathway and white matter microstructure in bipolar disorder.
    European archives of psychiatry and clinical neuroscience, 2018, Volume: 268, Issue:2

    Topics: Adult; Bipolar Disorder; Diffusion Tensor Imaging; Female; Humans; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Magnetic Resonance Imaging; Male; Middle Aged; Serotonin; Signal Transduction; Tryptophan; White Matter; Young Adult

2018
Intracerebroventricular Administration of Streptozotocin as an Experimental Approach to Depression: Evidence for the Involvement of Proinflammatory Cytokines and Indoleamine-2,3-Dioxygenase.
    Neurotoxicity research, 2017, Volume: 31, Issue:4

    Topics: Animals; Blood Glucose; Cytokines; Depression; Disease Models, Animal; Grooming; Hippocampus; Hydroxyindoleacetic Acid; Immobility Response, Tonic; Indoleamine-Pyrrole 2,3,-Dioxygenase; Infusions, Intraventricular; Kynurenine; Male; Mice; Minocycline; Serotonin; Streptozocin; Tryptophan

2017
Disturbed tryptophan metabolism correlating to progression and metastasis of esophageal squamous cell carcinoma.
    Biochemical and biophysical research communications, 2017, 05-06, Volume: 486, Issue:3

    Topics: 5-Hydroxytryptophan; Aged; Biomarkers, Tumor; Carcinoma, Squamous Cell; Case-Control Studies; Disease Progression; Early Diagnosis; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Humans; Hydroxyindoleacetic Acid; Kynurenine; Lymphatic Metastasis; Male; Metabolome; Middle Aged; Prognosis; Serotonin; Tryptophan

2017
Chronic trans-astaxanthin treatment exerts antihyperalgesic effect and corrects co-morbid depressive like behaviors in mice with chronic pain.
    Neuroscience letters, 2018, Jan-01, Volume: 662

    Topics: Analgesics; Animals; Behavior, Animal; Chronic Pain; Cytokines; Depression; Hydroxyindoleacetic Acid; Hyperalgesia; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Male; Mice, Inbred ICR; Neuralgia; Sciatic Nerve; Serotonin; Stereoisomerism; Tryptophan; Xanthophylls

2018
Simultaneous determination of tryptophan, kynurenine, kynurenic acid and two monoamines in rat plasma by HPLC-ECD/DAD.
    Journal of pharmaceutical and biomedical analysis, 2018, Sep-05, Volume: 158

    Topics: Amino Acids, Essential; Animals; Boron; Chemical Fractionation; Chromatography, High Pressure Liquid; Depression; Diamond; Electrochemical Techniques; Electrodes; Fluorescence; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Limit of Detection; Models, Animal; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Serotonin; Tryptophan

2018
Tryptophan and Kynurenine Metabolites: Are They Related to Depression?
    Neuropsychobiology, 2019, Volume: 77, Issue:1

    Topics: Adult; Bipolar Disorder; Case-Control Studies; Depressive Disorder, Major; Female; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; ortho-Aminobenzoates; Suicide, Attempted; Tryptophan; Xanthurenates

2019
Serum xanthurenic acid levels: Reduced in subjects at ultra high risk for psychosis.
    Schizophrenia research, 2019, Volume: 208

    Topics: Adolescent; Adult; Disease Progression; Female; Humans; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Male; ortho-Aminobenzoates; Prodromal Symptoms; Psychotic Disorders; Quinolinic Acid; Risk; Schizophrenia; Tryptophan; Xanthurenates; Young Adult

2019
Monitoring of kynurenine pathway metabolites, neurotransmitters and their metabolites in blood plasma and brain tissue of individuals with latent toxoplasmosis.
    Journal of pharmaceutical and biomedical analysis, 2019, Jun-05, Volume: 170

    Topics: Animals; Brain; Chromatography, High Pressure Liquid; Hydroxyindoleacetic Acid; Kynurenine; Male; Neurotransmitter Agents; Plasma; Quinolinic Acid; Rats; Rats, Wistar; Serotonin; Tandem Mass Spectrometry; Toxoplasmosis; Tryptophan

2019
Tryptophan pathway catabolites (serotonin, 5-hydroxyindolacetic acid, kynurenine) and enzymes (monoamine oxidase and indole amine 2,3 dioxygenase) in patients with septic shock: A prospective observational study versus healthy controls.
    Medicine, 2020, Volume: 99, Issue:19

    Topics: Aged; Case-Control Studies; Female; Humans; Hydroxyindoleacetic Acid; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Male; Middle Aged; Monoamine Oxidase; Organ Dysfunction Scores; Prospective Studies; Serotonin; Shock, Septic; Survival Rate; Tryptophan

2020
Sex and race differences of cerebrospinal fluid metabolites in healthy individuals.
    Metabolomics : Official journal of the Metabolomic Society, 2021, 01-18, Volume: 17, Issue:2

    Topics: Adult; alpha-Tocopherol; Cerebrospinal Fluid; Cysteine; Female; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Kynurenine; Male; Melatonin; Metabolome; Metabolomics; Race Factors; Serotonin; Sex Characteristics; Sex Factors; Uric Acid; Xanthine; Xanthines

2021
Disturbance of neurotransmitter metabolism in drug-naïve, first-episode major depressive disorder: a comparative study on adult and adolescent cohorts.
    European archives of psychiatry and clinical neuroscience, 2022, Volume: 272, Issue:7

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adolescent; Adult; Biomarkers; Depressive Disorder, Major; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Methoxyhydroxyphenylglycol; Neurotransmitter Agents; Norepinephrine; Serotonin; Tryptophan; Vanilmandelic Acid

2022
A sensitive UPLC-MS/MS method for the simultaneous determination of the metabolites in the tryptophan pathway in rat plasma.
    Journal of pharmaceutical and biomedical analysis, 2022, Sep-20, Volume: 219

    Topics: Acute Kidney Injury; Animals; Biomarkers; Chromatography, High Pressure Liquid; Chromatography, Liquid; Hydroxyindoleacetic Acid; Kidney Failure, Chronic; Kynurenic Acid; Kynurenine; Rats; Tandem Mass Spectrometry; TRPM Cation Channels; Tryptophan

2022
Simultaneous quantification of tryptophan metabolites by liquid chromatography tandem mass spectrometry during early human pregnancy.
    Clinical chemistry and laboratory medicine, 2023, 02-23, Volume: 61, Issue:3

    Topics: 5-Hydroxytryptophan; Chromatography, High Pressure Liquid; Chromatography, Liquid; Female; Humans; Hydroxyindoleacetic Acid; Infant; Kynurenine; Pregnancy; Reproducibility of Results; Serotonin; Tandem Mass Spectrometry; Tryptophan

2023
Comparative analysis of tryptophan and downstream metabolites of the kynurenine and serotonin pathways in patients with arterial hypertension and coronary artery disease.
    Kardiologiia, 2022, Nov-30, Volume: 62, Issue:11

    Topics: Atherosclerosis; Coronary Artery Disease; Humans; Hydroxyindoleacetic Acid; Hypertension; Kynurenic Acid; Kynurenine; Quinolinic Acid; Serotonin; Tryptophan

2022
Beneficial Effect of Increased Tryptophan Intake on Its Metabolism and Mental State of the Elderly.
    Nutrients, 2023, Feb-07, Volume: 15, Issue:4

    Topics: Aged; Chromatography, Liquid; Humans; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Tryptophan

2023
Changes in Tryptophan Metabolism on Serotonin and Kynurenine Pathways in Patients with Irritable Bowel Syndrome.
    Nutrients, 2023, Mar-03, Volume: 15, Issue:5

    Topics: Chromatography, Liquid; Humans; Hydroxyindoleacetic Acid; Irritable Bowel Syndrome; Kynurenic Acid; Kynurenine; Serotonin; Tandem Mass Spectrometry; Tryptophan

2023
Reduced Intake of Dietary Tryptophan Improves Beneficial Action of Budesonide in Patients with Lymphocytic Colitis and Mood Disorders.
    Nutrients, 2023, Mar-30, Volume: 15, Issue:7

    Topics: Budesonide; Colitis, Lymphocytic; Diet; Humans; Hydroxyindoleacetic Acid; Kynurenine; Mood Disorders; Tryptophan

2023