hydroxyindoleacetic acid has been researched along with fenfluramine in 116 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 42 (36.21) | 18.7374 |
| 1990's | 49 (42.24) | 18.2507 |
| 2000's | 21 (18.10) | 29.6817 |
| 2010's | 4 (3.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Invernizzi, R; Miranda, F; Samanin, R | 1 |
| Sanders-Bush, E; Steranka, LR | 2 |
| Boulanger, M; Duhault, J; Malen, C; Schmitt, H; Voisin, C | 1 |
| Clineschmidt, BV; McGuffin, JC; Pflueger, AB; Totaro, JA; Wishousky, TI; Zacchei, AG | 1 |
| Fuller, RW; Hemrick, SK; Snoddy, HD | 1 |
| Garncarczyk, L; Maj, J; Mogilnicka, E; Pawlowski, L | 1 |
| Chase, TN; Shoulson, I | 1 |
| Abercrombie, ED; Jackson, D | 1 |
| Crespi, F; Möbius, C; Wright, IK | 1 |
| Brown, RP; DeMeo, M; Leon, AC; Linnoila, M; Mann, JJ; McBride, PA; Mieczkowski, T; Myers, JE; Stanley, M | 1 |
| Culp, S; DeSouza, EB; Lehmann, J; Zaczek, R | 1 |
| Artigas, F; Martín, F | 1 |
| Kaufman, LN; Leigh, FS; Young, JB | 1 |
| Martin, RJ; Mullen, BJ | 1 |
| Bolaños-Jimenez, F; Fattaccini, CM; Gozlan, H; Hamon, M | 1 |
| Crespi, F; Garratt, JC; Marsden, CA; Sleight, AJ | 1 |
| Gleason, R; Morse, AN; Sarkissian, CF; Wurtman, RJ | 1 |
| Fattaccini, CM; Gozlan, H; Hamon, M | 1 |
| Gardier, AM; Wurtman, RJ | 1 |
| Katz, JL; Martello, AL; Martello, MB; Molliver, ME; Ricaurte, GA; Wilson, MA | 1 |
| Jain, A; Meyendorff, E; Stanley, B; Stanley, M; Träskman-Bendz, L | 1 |
| Bendotti, C; Garattini, S; Invernizzi, R; Mennini, T; Samanin, R | 1 |
| Carlton, J; Rowland, NE | 2 |
| Baker, PC; Bauman, GP; Goodrich, CA | 1 |
| Rowland, NE | 1 |
| Brammer, GL; Geller, E; McGuire, MT; Raleigh, MJ; Ritvo, ER; Yuwiler, A | 1 |
| Anderson, GM; Teff, KL; Young, SN | 1 |
| Garattini, S; Mennini, T; Samanin, R | 1 |
| Asin, KE; Klitenick, MA; Wirtshafter, D | 1 |
| Bianchetti, A; Miranda, GF; Poggesi, E; Samanin, R; Unkovic, J | 1 |
| Fuller, RW; Perry, KW; Snoddy, HD | 1 |
| Kleven, MS; Schuster, CR; Seiden, LS | 1 |
| De Luigi, A; De Simoni, MG; Fodritto, F; Garattini, S; Juraszczyk, Z | 1 |
| Fuller, RW; Robertson, DW; Snoddy, HD | 1 |
| Schaechter, JD; Wurtman, RJ | 1 |
| Hernandez, L; Hoebel, BG; Schwartz, D | 1 |
| Auerbach, SB; Minzenberg, MJ; Wilkinson, LO | 1 |
| Laferrere, B; Wurtman, RJ | 1 |
| Garattini, S; Samanin, R | 1 |
| Gallager, DA; Sanders-Bush, E; Sulser, F | 1 |
| Gessa, GL; Perez-Cruet, J; Stern, S; Tagliamonte, A; Tagliamonte, P | 1 |
| Costa, E; Revuelta, A | 1 |
| Garattini, S | 1 |
| Gessa, GL; Tagliamonte, A | 1 |
| Duhault, J; Verdavainne, C | 1 |
| Invernizzi, R; Kmieciak-Kolada, K; Samanin, R | 1 |
| Botting, R; Morinan, A | 1 |
| Clemens, JA; Fuller, RW; Molloy, BB; Snoddy, HD | 1 |
| Maj, J; Michaluk, J; Rogóz, Z; Skuza, G; Vetulani, J | 1 |
| Albano, C; Bacigalupo, F; Bartolini, A; Farinini, D; Firpo, MP; Pizio, N; Roccatagliata, G | 1 |
| Groppetti, A; Olgiati, VR; Parenti, M; Tirone, F | 1 |
| Root-Bernstein, RS; Westall, FC | 1 |
| Bremond, J; Cohen, Y; Jacquot, C; Orosco, M | 1 |
| Cooper, TB; Malone, KM; Mann, JJ; Mieczkowski, T; Myers, JE; Stull, SD; Thase, ME | 1 |
| Fischer, C; Hatzidimitriou, G; Katz, J; McCann, U; Ricaurte, G; Ridenour, A; Yuan, J | 1 |
| Curzon, G; Datla, KP; Oluyomi, AO | 1 |
| Björntorp, P | 1 |
| Hengeveld, MW | 1 |
| Crespi, D; Gobbi, M; Mennini, T | 1 |
| Cowen, PJ; Series, HG; Sharp, T | 1 |
| Bonhomme, N; De Deurwaerdère, P; Le Moal, M; Spampinato, U | 1 |
| Kreiss, DS; Lucki, I; Wieland, S | 1 |
| Colado, MI; Green, AR; Murray, TK | 1 |
| Anelli, M; Caccia, S; Ferrarese, A; Fracasso, C; Garattini, S | 1 |
| Auerbach, SB; Rutter, JJ | 1 |
| Borve, T; Fisher, H; Johnson, SK; Pole, N; Wagner, GC | 1 |
| Bores, GM; Chesson, SM; Corbett, R; Kongsamut, S; Petko, WW; Roehr, JE; Smith, CP; Woods-Kettelberger, AT | 1 |
| Bergami, A; Caccia, S; Confalonieri, S; Fracasso, C; Garattini, S; Guiso, G | 1 |
| Collins, P; Hindmarsh, JG; Hunt, S; Jenner, P; Rose, S | 1 |
| Anelli, M; Caccia, S; Cinquanta, M; Crespi, D; Frittoli, E; Giorcelli, P; Gobbi, M; Mennini, T | 1 |
| McMahon, LR; Wellman, PJ | 1 |
| Bert, L; Gardier, AM; Jacquot, C; Renaud, B; Robert, F; Rocher, C; Trouvin, JH | 1 |
| Bergami, A; Caccia, S; Caltavuturo, C; Gobbi, M; Mennini, T; Valle, FD | 1 |
| Colado, MI; Green, AR; Misra, A; Murray, TK; Williams, JL | 1 |
| Malberg, JE; Seiden, LS | 1 |
| Curzon, G; Datla, KP | 1 |
| Coccaro, EF; Cooper, TB; Hauger, RL; Kavoussi, RJ | 1 |
| Apelqvist, G; Bengtsson, F; Bergqvist, PB; Hjorth, S; Wikell, C | 1 |
| Bantle, JP; Raatz, S; Redmon, B | 1 |
| Bowyer, JF; Clausing, P; Newport, GD | 1 |
| Collins, P; Hindmarsh, JG; Jenner, P; Rose, S | 1 |
| Edwards, GL; Grossman, BM; Hobbs, JK; Martin, RJ | 1 |
| Ayestas, MA; Baumann, MH; Rothman, RB | 1 |
| Coscina, DV; Currie, PJ; Fletcher, PJ | 1 |
| Coccaro, EF; Cooper, TB; Ferris, CF; Hauger, RL; Kavoussi, RJ | 1 |
| McCann, UD; Ricaurte, GA; Yuan, J | 1 |
| Yeh, SY | 1 |
| Slikker, W; Stewart, CW | 1 |
| Chen, HN; Li, XY; Wu, GC; Xu, SF; Zhu, CB; Zhu, YH | 1 |
| Cryan, JF; Harkin, A; Kelly, JP; Leonard, BE; Naughton, M | 1 |
| Syce, JA; Valodia, P | 1 |
| Callahan, BT; Cord, BJ; Ricaurte, GA | 1 |
| Ayestas, MA; Baumann, MH; Dersch, CM; Rothman, RB | 1 |
| Ebinger, G; Loo, JV; Michotte, Y; Sarre, S; Smolders, I | 1 |
| Delatte, MS; McCann, UD; Moerschbaecher, JM; Ricaurte, GA; Stevenson, MW; Winsauer, PJ; Yuan, J | 1 |
| Assié, MB; Kleven, MS; Koek, W; Prinssen, EP | 1 |
| Fisher, H; Halladay, AK; Hesse, K; Kirschner, E; Wagner, GC | 1 |
| Aldegunde, M; Ruibal, C; Soengas, JL | 1 |
| Callahan, BT; Cord, BJ; McCann, UD; Ricaurte, GA; Yuan, J | 1 |
| Brodsky, B; Campbell, C; Cooper, TB; Kegeles, LS; Keilp, J; Malone, KM; Mann, JJ; Oquendo, MA; Parsey, RV; Placidi, GP; van Heertum, RL | 1 |
| Cooper, TB; Haas, GL; Li, S; Malone, KM; Mann, JJ; Waternaux, C | 1 |
| Alesh, Y; Birger, M; Cohen, D; Grishpan, C; Kotelr, M; Swartz, M | 1 |
| Baumann, MH; Cadet, JL; Dersch, CM; Jayanthi, S; Prisinzano, T; Rice, KC; Rothman, RB; Wang, X | 1 |
| Cremers, TI; de Boer, SF; Koolhaas, JM; Lieuwes, N; van der Vegt, BJ | 1 |
| Blankenmeyer, TL; Brown-Strittholt, CA; Gudelsky, GA; Skelton, MR; Vorhees, CV; Williams, MT | 1 |
| Belzung, C; Bodard, S; Chalon, S; Galineau, L; Guilloteau, D; Kodas, E | 1 |
| Breuer, ME; Olivier, B; van der Stelt, HM; Westenberg, HG | 1 |
| Aznar, S; Knudsen, GM; Kornum, BR; Licht, CL; Weikop, P | 1 |
| Aznar, S; Knudsen, GM; Kornum, BR; Moller, A; Ronn, LC; Weikop, P | 1 |
| Aldegunde, M; Caamaño-Tubío, RI; Ferreiro, S; Pérez, J | 1 |
| Alves, SE; Correa, L; Gautreaux, C; Gordon, M; Hickey, GJ; Lorrain, DS; Lubbers, LS; Luine, V; Zafian, PT | 1 |
| Caron, MG; Cools, MJ; Flik, G; Folgering, JH; Jacobsen, JP; Peterson, S; Sachs, BD; Setola, V; Siesser, WB | 1 |
| Galfalvy, HC; Hibbeln, JR; Keilp, JG; Malone, KM; Mann, JJ; Oquendo, MA; Sublette, ME | 1 |
| Bolhuis, JE; Güntürkün, O; Kjaer, JB; Kops, MS; Korte, SM; Korte-Bouws, GA; Olivier, B; Westphal, KG | 1 |
6 review(s) available for hydroxyindoleacetic acid and fenfluramine
| Article | Year |
|---|---|
Neurochemical mechanism of action of drugs which modify feeding via the serotoninergic system.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Appetite; Appetite Depressants; Brain; Brain Chemistry; Dopamine; Endorphins; Feeding Behavior; Fenfluramine; gamma-Aminobutyric Acid; Hydroxyindoleacetic Acid; Neural Pathways; Norepinephrine; Piperazines; Pyridines; Quipazine; Rats; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1986 |
Tolerance to fenfluramine anorexia: fact or fiction?
Topics: Animals; Behavior Therapy; Body Weight; Brain; Brain Chemistry; Drug Tolerance; Feeding Behavior; Female; Fenfluramine; Gastric Emptying; Hydroxyindoleacetic Acid; Intestines; Male; Norfenfluramine; Obesity; Rats; Rats, Inbred Strains; Self Stimulation; Serotonin; Stomach | 1986 |
From fenfluramine racemate to d-fenfluramine. Specificity and potency of the effects on the serotoninergic system and food intake.
Topics: Amines; Animals; Brain; Dextroamphetamine; Eating; Female; Fenfluramine; Hydroxyindoleacetic Acid; Isomerism; Rats; Receptors, Dopamine; Receptors, Serotonin; Serotonin | 1987 |
Serotonin and the pharmacology of eating disorders.
Topics: Animals; Appetite; Brain; Brain Chemistry; Eating; Feeding and Eating Disorders; Feeding Behavior; Fenfluramine; Humans; Hydroxyindoleacetic Acid; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists | 1989 |
Neuroendocrine abnormalities in human obesity.
Topics: Animals; Corticotropin-Releasing Hormone; Female; Fenfluramine; Humans; Hydroxyindoleacetic Acid; Male; Neurosecretory Systems; Obesity | 1995 |
Aggression: the testosterone-serotonin link.
Topics: Aggression; Animals; Female; Fenfluramine; Humans; Hydroxyindoleacetic Acid; Macaca mulatta; Male; Personality Disorders; Prolactin; Reference Values; Serotonin; Testosterone; Violence | 2003 |
1 trial(s) available for hydroxyindoleacetic acid and fenfluramine
| Article | Year |
|---|---|
Fenfluramine in man: hypophagia associated with diminished serotonin turnover.
Topics: Adult; Appetite; Body Weight; Clinical Trials as Topic; Depression, Chemical; Dopamine; Feeding and Eating Disorders; Female; Fenfluramine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Placebos; Probenecid; Serotonin | 1975 |
109 other study(ies) available for hydroxyindoleacetic acid and fenfluramine
| Article | Year |
|---|---|
Studies on the mechanism of the interaction of narcotic analgesics with brain serotonin.
Topics: Analgesics, Opioid; Animals; Brain; Brain Stem; Female; Fenfluramine; Hydroxyindoleacetic Acid; Raphe Nuclei; Rats; Serotonin; Time Factors | 1979 |
Long-term effects of fenfluramine on central serotonergic mechanisms.
Topics: Animals; Brain; Catecholamines; Fenfluramine; Fluoxetine; Hydroxyindoleacetic Acid; Male; Rats; Serotonin; Tryptophan Hydroxylase | 1979 |
Fenfluramine and 5-hydroxytryptamine. Part 2: Involvement of brain 5-hydroxytryptamine in the anorectic activity of fenfluramine.
Topics: Amides; Animals; Appetite Depressants; Brain; Brain Chemistry; Clomipramine; Fenclonine; Fenfluramine; Hydroxyindoleacetic Acid; Male; Norfenfluramine; p-Chloroamphetamine; Rats; Serotonin; Telencephalon; Time Factors; Tyramine | 1975 |
Fenfluramine and brain serotonin.
Topics: 5-Hydroxytryptophan; Aging; Animals; Animals, Newborn; Brain; Dealkylation; Dihydroxyphenylalanine; Female; Fenfluramine; Fluoxetine; Hydroxyindoleacetic Acid; Rats; Serotonin; Time Factors | 1978 |
Species differences in the rate of disappearance of fenfluramine and its effects on brain serotonin neurons.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Fenfluramine; Hydroxyindoleacetic Acid; Kinetics; Male; Neurons; Rats; Serotonin; Synaptosomes; Tryptophan Hydroxylase | 1979 |
Effects of fenfluramine and norfenfluramine on brain serotonin metabolism in rats.
Topics: Animals; Brain; Fenfluramine; Hydroxyindoleacetic Acid; Male; Norfenfluramine; Rats; Serotonin; Time Factors | 1978 |
Central D-fenfluramine action.
Topics: Animals; Anura; Benserazide; Body Temperature; Brain; Depression, Chemical; Fenfluramine; Hydroxyindoleacetic Acid; Levodopa; Male; Mice; Motor Activity; Rana temporaria; Rats; Reflex; Serotonin | 1975 |
In vivo neurochemical evaluation of striatal serotonergic hyperinnervation in rats depleted of dopamine at infancy.
Topics: Animals; Animals, Newborn; Biogenic Amines; Corpus Striatum; Dialysis; Dopamine; Extracellular Space; Fenfluramine; Fluoxetine; Hydroxyindoleacetic Acid; Potassium; Rats; Rats, Inbred Strains; Serotonin | 1992 |
Isolation rearing of rats alters release of 5-hydroxytryptamine and dopamine in the frontal cortex: an in vivo electrochemical study.
Topics: Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Dopamine; Electric Stimulation; Electrochemistry; Fenfluramine; Hydroxyindoleacetic Acid; Male; Motor Activity; Potassium Chloride; Rats; Rats, Inbred Strains; Reference Values; Serotonin; Social Isolation | 1992 |
Relationship between central and peripheral serotonin indexes in depressed and suicidal psychiatric inpatients.
Topics: Adult; Blood Platelets; Depressive Disorder; Female; Fenfluramine; Hospitalization; Humans; Hydroxyindoleacetic Acid; Male; Mental Disorders; Prolactin; Receptors, Serotonin; Serotonin; Suicide, Attempted | 1992 |
Regional distribution to recovery of 5-HT levels after administration of "atrophins" MDMA and D,L-fenfluramine. Stereospecificity and comparison with 5,7-dihydroxytryptamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; 5,7-Dihydroxytryptamine; Animals; Atrophy; Brain; Cerebral Ventricles; Designer Drugs; Dopamine; Fenfluramine; Homovanillic Acid; Hydroxyindoleacetic Acid; Injections, Intraventricular; Male; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Organ Specificity; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism | 1992 |
Simultaneous effects of p-chloroamphetamine, d-fenfluramine, and reserpine on free and stored 5-hydroxytryptamine in brain and blood.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Fenfluramine; Hydroxyindoleacetic Acid; Male; Osmolar Concentration; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Reserpine; Serotonin | 1992 |
Diminished epinephrine excretion in genetically obese (ob/ob) mice and monosodium glutamate-treated rats.
Topics: Adrenal Medulla; Analysis of Variance; Animals; Catecholamines; Epinephrine; Female; Fenfluramine; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Rats; Rats, Inbred Strains; Serotonin; Sodium Glutamate | 1992 |
The effect of dietary fat on diet selection may involve central serotonin.
Topics: Animals; Blood; Brain; Corn Oil; Dietary Fats; Fats; Fenfluramine; Food Preferences; Hydroxyindoleacetic Acid; Male; Rats; Rats, Sprague-Dawley; Serotonin | 1992 |
Tianeptine stimulates uptake of 5-hydroxytryptamine in vivo in the rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamines; Animals; Antidepressive Agents, Tricyclic; Brain; Dopamine; Fenfluramine; Hydroxyindoleacetic Acid; Male; Rats; Rats, Inbred Strains; Serotonin; Synaptosomes; Thiazepines | 1990 |
In vivo evidence that 5-hydroxytryptamine (5-HT) neuronal firing and release are not necessarily correlated with 5-HT metabolism.
Topics: Action Potentials; Animals; Fenfluramine; Frontal Lobe; Hydroxyindoleacetic Acid; Male; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin | 1990 |
Effects of fluoxetine or D-fenfluramine on serotonin release from, and levels in, rat frontal cortex.
Topics: Animals; Cerebral Cortex; Dialysis; Fenfluramine; Fluoxetine; Hydroxyindoleacetic Acid; Kinetics; Male; Rats; Rats, Inbred Strains; Reference Values; Serotonin | 1990 |
Differential effects of d-fenfluramine and p-chloroamphetamine on H75/12-induced depletion of 5-hydroxytryptamine and dopamine in the rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamines; Animals; Brain; Brain Stem; Cerebral Cortex; Corpus Striatum; Dopamine; Fenfluramine; Hippocampus; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Monoamine Oxidase Inhibitors; p-Chloroamphetamine; Rats; Rats, Inbred Strains; Reference Values; Serotonin | 1991 |
Persistent blockade of potassium-evoked serotonin release from rat frontocortical terminals after fluoxetine administration.
Topics: Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Fenfluramine; Fluoxetine; Hydroxyindoleacetic Acid; Male; Potassium Chloride; Rats; Rats, Inbred Strains; Reference Values; Serotonin | 1991 |
Dexfenfluramine neurotoxicity in brains of non-human primates.
Topics: Animals; Axons; Brain Chemistry; Caudate Nucleus; Cerebral Cortex; Drug Administration Schedule; Drug Evaluation, Preclinical; Female; Fenfluramine; Hydroxyindoleacetic Acid; Male; Neurons; Saimiri; Serotonin; Thalamus | 1991 |
The effects of fenfluramine on suicidal behavior.
Topics: Adult; Behavior; Fenfluramine; Humans; Hydroxyindoleacetic Acid; Middle Aged; Psychiatric Status Rating Scales; Serotonin; Suicide | 1986 |
Biochemical and functional effects of fenfluramine in maturing mice.
Topics: Age Factors; Animals; Body Temperature; Body Weight; Brain; Fenfluramine; Hydroxyindoleacetic Acid; Mice; Serotonin | 1986 |
Effects of fenfluramine on food intake, body weight, gastric emptying and brain monoamines in Syrian hamsters.
Topics: Animals; Biogenic Amines; Body Weight; Brain Chemistry; Cricetinae; Dopamine; Dose-Response Relationship, Drug; Feeding Behavior; Female; Fenfluramine; Food Deprivation; Gastric Emptying; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Mesocricetus; Motor Activity; Serotonin | 1986 |
Effect of continuous infusions of dexfenfluramine on food intake, body weight and brain amines in rats.
Topics: Amines; Animals; Body Weight; Brain; Delayed-Action Preparations; Dopamine; Eating; Female; Fenfluramine; Hydroxyindoleacetic Acid; Male; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin | 1986 |
Effects of chronic fenfluramine on blood serotonin, cerebrospinal fluid metabolites, and behavior in monkeys.
Topics: Aggression; Animals; Behavior, Animal; Chlorocebus aethiops; Fenfluramine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Serotonin; Social Behavior | 1986 |
Serotonin in cisternal cerebrospinal fluid of the rat: measurement and use as an index of functionally active serotonin.
Topics: Amitriptyline; Animals; Brain Chemistry; Fenfluramine; Hydroxyindoleacetic Acid; Male; Pargyline; Rats; Rats, Inbred Strains; Serotonin; Tryptophan | 1987 |
Evidence against serotonin involvement in the hyperactivity produced by injections of muscimol into the median raphe nucleus.
Topics: 5,7-Dihydroxytryptamine; Animals; Fenclonine; Fenfluramine; Hydroxyindoleacetic Acid; Male; Motor Activity; Muscimol; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin | 1987 |
Reduction of normal food intake in rats and dogs and inhibition of experimentally induced hyperphagia in rats by CM 57373 and fenfluramine.
Topics: Animals; Appetite Depressants; Body Weight; Diet; Dogs; Eating; Feeding and Eating Disorders; Female; Fenfluramine; Hydroxyindoleacetic Acid; Hyperphagia; Insulin; Male; Piperidines; Rats; Rats, Inbred Strains; Serotonin | 1988 |
Metabolism of fenfluramine to norfenfluramine in guinea-pigs.
Topics: Animals; Brain Chemistry; Fenfluramine; Guinea Pigs; Hydroxyindoleacetic Acid; Male; Norfenfluramine; Serotonin | 1988 |
Effect of depletion of brain serotonin by repeated fenfluramine on neurochemical and anorectic effects of acute fenfluramine.
Topics: Animals; Appetite Depressants; Brain; Dopamine; Dose-Response Relationship, Drug; Drug Tolerance; Eating; Fenfluramine; Hydroxyindoleacetic Acid; Male; Milk; Rats; Rats, Inbred Strains; Time Factors | 1988 |
Different effects of fenfluramine isomers and metabolites on extracellular 5-HIAA in nucleus accumbens and hippocampus of freely moving rats.
Topics: Animals; Extracellular Space; Fenfluramine; Hippocampus; Hydroxyindoleacetic Acid; Male; Motor Activity; Norfenfluramine; Nucleus Accumbens; Rats; Septal Nuclei; Serotonin; Stereoisomerism | 1988 |
Mechanisms of effects of d-fenfluramine on brain serotonin metabolism in rats: uptake inhibition versus release.
Topics: 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; Animals; Brain; Dose-Response Relationship, Drug; Fenfluramine; Fluoxetine; Hydroxyindoleacetic Acid; Kinetics; Male; Rats; Rats, Inbred Strains; Reference Values; Serotonin | 1988 |
Effect of chronic D-fenfluramine administration on rat hypothalamic serotonin levels and release.
Topics: Animals; Dose-Response Relationship, Drug; Fenfluramine; Hydroxyindoleacetic Acid; Hypothalamus; Kinetics; Male; Rats; Rats, Inbred Strains; Serotonin; Tryptophan | 1989 |
Fenfluramine administered systemically or locally increases extracellular serotonin in the lateral hypothalamus as measured by microdialysis.
Topics: Animals; Dopamine; Dose-Response Relationship, Drug; Extracellular Space; Fenfluramine; Hydroxyindoleacetic Acid; Hypothalamic Area, Lateral; Male; Microinjections; Rats; Rats, Inbred Strains; Serotonin; Time Factors | 1989 |
Extracellular serotonin and 5-hydroxyindoleacetic acid in hypothalamus of the unanesthetized rat measured by in vivo dialysis coupled to high-performance liquid chromatography with electrochemical detection: dialysate serotonin reflects neuronal release.
Topics: Animals; Chromatography, High Pressure Liquid; Fenfluramine; Fluoxetine; Hydroxyindoleacetic Acid; Hypothalamus; Male; Rats; Serotonin | 1989 |
Effect of D-fenfluramine on serotonin release in brains of anaesthetized rats.
Topics: Anesthesia; Animals; Brain; Fenfluramine; Hydroxyindoleacetic Acid; Male; Rats; Rats, Inbred Strains; Serotonin; Tryptophan | 1989 |
On the mechanism of brain 5-hydroxytryptamine depletion by p-chloroamphetamine and related drugs and the specificity of their action.
Topics: Amphetamine; Animals; Brain; Brain Chemistry; Carbon Radioisotopes; Catecholamines; Chlorine; Fenclonine; Fenfluramine; Hippocampus; Hydroxyindoleacetic Acid; Hypnotics and Sedatives; Methamphetamine; Neurons; Serotonin; Serotonin Antagonists; Synaptosomes; Time Factors; Tritium; Tryptophan Hydroxylase | 1974 |
Effect of psychotropic drugs on tryptophan concentration in the rat brain.
Topics: Alkaloids; Animals; Apomorphine; Aporphines; Body Temperature; Brain Chemistry; Butyrates; Chlorpromazine; Cold Temperature; Cyclic AMP; Dextroamphetamine; Fenclonine; Fenfluramine; Haloperidol; Hot Temperature; Hydroxybutyrates; Hydroxyindoleacetic Acid; Lithium; Male; Methyltyrosines; Morphine; Nucleosides; Phenelzine; Phenmetrazine; Probenecid; Rats; Reserpine; Serotonin; Tryptophan; Tyrosine | 1971 |
Norfenfluramine and serotonin turnover rate in the rat brain.
Topics: Amines; Animals; Atropine; Body Temperature; Brain; Brain Chemistry; Brain Stem; Carbon Isotopes; Corpus Striatum; Diencephalon; Drug Interactions; Fenfluramine; Heart; Hydroxyindoleacetic Acid; Kinetics; Male; Mathematics; Myocardium; Rats; Serotonin; Spectrometry, Fluorescence; Telencephalon; Time Factors | 1972 |
[Similarities and differences between fenfluramine and amphetamine].
Topics: Amphetamine; Animals; Blood Pressure; Blood Vessels; Brain Chemistry; Drug Interactions; Fenfluramine; Humans; Hydroxyindoleacetic Acid; Nerve Endings; Phenylacetates; Rats | 1973 |
Possible role of free serum tryptophan in the control of brain tryptophan level and serotonin synthesis.
Topics: Amino Acids; Animals; Apomorphine; Blood-Brain Barrier; Brain; Chlorpromazine; Cold Temperature; Desipramine; Fenfluramine; Haloperidol; Hydroxyindoleacetic Acid; Kinetics; Methyltyrosines; Morphine; Neurons; Phenelzine; Protein Binding; Rats; Serotonin; Stimulation, Chemical; Tryptophan; Tryptophan Hydroxylase | 1974 |
[Modification of the cerebral serotonin level in the rat by trifluoromethyl-2-phenyl ethyl aminopropane (Fenfluramine 768 S)].
Topics: 5-Hydroxytryptophan; Animals; Appetite Depressants; Brain; Brain Chemistry; Carboxy-Lyases; Dopa Decarboxylase; Epididymis; Fenfluramine; Heart; Hydroxyindoleacetic Acid; Male; Mixed Function Oxygenases; Monoamine Oxidase; Norepinephrine; Rats; Serotonin; Tryptophan | 1967 |
Is receptor activation involved in the mechanism by which (+)-fenfluramine and (+)-norfenfluramine deplete 5-hydroxytryptamine in the rat brain?
Topics: Animals; Brain; Drug Synergism; Female; Fenfluramine; Hydroxyindoleacetic Acid; In Vitro Techniques; Metergoline; Norfenfluramine; Rats; Receptors, Serotonin; Reserpine; Serotonin | 1982 |
Involvement of 5-hydroxytryptamine in the analgesic action of pethidine and morphine in mice.
Topics: Analgesics; Animals; Body Temperature; Brain Chemistry; Fenclonine; Fenfluramine; Hydroxyindoleacetic Acid; Male; Meperidine; Mice; Morphine; Reaction Time; Serotonin; Tryptophan | 1982 |
Effect of norfenfluramine and two structural analogues on brain 5-hydroxyindoles and serum prolactin in rats.
Topics: Animals; Brain; Fenfluramine; Hydroxyindoleacetic Acid; Indoles; Male; Norfenfluramine; Prolactin; Rats; Rats, Inbred Strains; Stereoisomerism; Structure-Activity Relationship | 1982 |
Central action of amitriptyline N-oxide.
Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Brain; Brain Chemistry; Fenfluramine; Hydroxyindoleacetic Acid; Lysergic Acid Diethylamide; Male; Methoxyhydroxyphenylglycol; Mice; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Tryptamines | 1982 |
[Effect of fenfluramine in Huntington Chorea].
Topics: 5-Hydroxytryptophan; Adult; Female; Fenfluramine; Homovanillic Acid; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Middle Aged | 1983 |
Presence of opiate receptors on striatal serotoninergic nerve terminals.
Topics: Animals; Corpus Striatum; Dopamine; Enkephalin, Methionine; Fenfluramine; Hydroxyindoleacetic Acid; Male; Morphine; Naloxone; Nerve Degeneration; Neurons; Rats; Rats, Inbred Strains; Receptors, Opioid; Serotonin | 1983 |
Fenfluramine binds 5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Chemical Phenomena; Chemistry; Fenfluramine; Hydroxyindoleacetic Acid; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Serotonin; Structure-Activity Relationship; Tryptophan | 1984 |
Fenfluramine and brain transmitters in the obese Zucker rat.
Topics: Animals; Body Weight; Brain Chemistry; Catecholamines; Dopamine; Feeding Behavior; Female; Fenfluramine; gamma-Aminobutyric Acid; Hydroxyindoleacetic Acid; Neurotransmitter Agents; Norepinephrine; Obesity; Rats; Rats, Zucker | 1984 |
Fenfluramine challenge test as a predictor of outcome in major depression.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Depressive Disorder; Female; Fenfluramine; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Predictive Value of Tests; Treatment Outcome | 1993 |
Dexfenfluramine and serotonin neurotoxicity: further preclinical evidence that clinical caution is indicated.
Topics: Animals; Brain; Fenfluramine; Hydroxyindoleacetic Acid; Mice; Neurons; Rats; Rats, Sprague-Dawley; Saimiri; Serotonin; Species Specificity | 1994 |
Effects of d-fenfluramine on feeding and hypothalamic 5-hydroxytryptamine and dopamine in male and female rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Diet; Dopamine; Feeding Behavior; Female; Fenfluramine; Food Deprivation; Hydroxyindoleacetic Acid; Hypothalamus; Male; Rats; Rats, Sprague-Dawley; Serotonin; Sex Characteristics | 1994 |
Serotonin in attempted suicide.
Topics: Blood Platelets; Fenfluramine; Humans; Hydroxyindoleacetic Acid; Serotonin; Suicide, Attempted | 1994 |
Effects of fluoxetine on basal and K(+)-induced tritium release from synaptosomes preloaded with [3H]serotonin.
Topics: Animals; Cerebral Cortex; Fenfluramine; Fluoxetine; Hippocampus; Hydroxyindoleacetic Acid; Male; Pargyline; Potassium; Rats; Serotonin; Spinal Cord; Synaptosomes; Tritium | 1995 |
p-Chloroamphetamine (PCA), 3,4-methylenedioxy-methamphetamine (MDMA) and d-fenfluramine pretreatment attenuates d-fenfluramine-evoked release of 5-HT in vivo.
Topics: Amphetamines; Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Dextroamphetamine; Fenfluramine; Hydroxyindoleacetic Acid; Male; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; p-Chloroamphetamine; Potassium; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Serotonin | 1994 |
d-fenfluramine increases striatal extracellular dopamine in vivo independently of serotonergic terminals or dopamine uptake sites.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5,7-Dihydroxytryptamine; Anesthesia; Animals; Citalopram; Corpus Striatum; Dialysis; Dopamine; Dose-Response Relationship, Drug; Extracellular Space; Fenfluramine; Halothane; Hydroxyindoleacetic Acid; Male; Nomifensine; Rats; Rats, Sprague-Dawley; Serotonin; Tetrodotoxin | 1995 |
The presence of a serotonin uptake inhibitor alters pharmacological manipulations of serotonin release.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Chromatography, High Pressure Liquid; Citalopram; Corpus Striatum; Dialysis; Electrochemistry; Fenfluramine; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Sodium Channels; Tetrodotoxin | 1993 |
5-HT loss in rat brain following 3,4-methylenedioxymethamphetamine (MDMA), p-chloroamphetamine and fenfluramine administration and effects of chlormethiazole and dizocilpine.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Behavior, Animal; Body Temperature; Brain Chemistry; Cerebral Cortex; Chlormethiazole; Dizocilpine Maleate; Fenfluramine; Hippocampus; Hydroxyindoleacetic Acid; Male; N-Methyl-3,4-methylenedioxyamphetamine; p-Chloroamphetamine; Rats; Serotonin | 1993 |
The role of d-norfenfluramine in the indole-depleting effect of d-fenfluramine in the rat.
Topics: Animals; Brain; Brain Chemistry; Fenfluramine; Hydroxyindoleacetic Acid; Indoles; Injections, Intraperitoneal; Male; Norfenfluramine; Proadifen; Rats; Serotonin | 1993 |
Acute uptake inhibition increases extracellular serotonin in the rat forebrain.
Topics: 1-Naphthylamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Corpus Striatum; Diencephalon; Fenfluramine; Fluoxetine; Hydroxyindoleacetic Acid; Male; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Sertraline | 1993 |
Effects of monoaminergic agonists on alcohol-induced increases in mouse aggression.
Topics: Aggression; Animals; Behavior, Animal; Brain; Drug Synergism; Ethanol; Fenfluramine; Fluoxetine; Hydroxyindoleacetic Acid; Male; Mice; Tryptophan | 1993 |
Serotonergic activity of HP 184: does spontaneous release have a role?
Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Blepharoptosis; Brain; Drinking Behavior; Drug Synergism; Fenfluramine; Hippocampus; Hydroxyindoleacetic Acid; In Vitro Techniques; Indoles; Male; Mice; Norepinephrine; Pyridines; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Synaptosomes; Tetrabenazine | 1996 |
Depletion and time-course of recovery of brain serotonin after repeated subcutaneous dexfenfluramine in the mouse. A comparison with the rat.
Topics: Animals; Brain; Cerebral Cortex; Corpus Striatum; Dose-Response Relationship, Drug; Fenfluramine; Hippocampus; Hydroxyindoleacetic Acid; Male; Mice; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin | 1995 |
Repeated administration of escalating high doses of dexfenfluramine does not produce morphological evidence for neurotoxicity in the cortex of rats.
Topics: Animals; Appetite Depressants; Binding Sites; Biomarkers; Cerebral Cortex; Citalopram; Fenfluramine; GAP-43 Protein; Glial Fibrillary Acidic Protein; Hydroxyindoleacetic Acid; Male; Membrane Glycoproteins; Nerve Degeneration; Nerve Fibers; Nerve Regeneration; Nerve Tissue Proteins; Neurotoxins; Rats; Rats, Wistar; Serotonin | 1996 |
In vivo and in vitro interaction of flunarizine with D-fenfluramine serotonergic effects.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cerebral Cortex; Dopamine; Drug Interactions; Fenfluramine; Flunarizine; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Selective Serotonin Reuptake Inhibitors; Serotonin; Synaptosomes | 1996 |
Effects of systemic phenylpropanolamine and fenfluramine on serotonin activity within rat paraventricular hypothalamus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Appetite Depressants; Eating; Extracellular Space; Fenfluramine; Hydroxyindoleacetic Acid; Microdialysis; Paraventricular Hypothalamic Nucleus; Phenylpropanolamine; Rats; Rats, Sprague-Dawley; Receptors, Presynaptic; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists | 1996 |
Microdialysis monitoring of variations in extracellular levels of serotonin, GABA and excitatory amino acids in the frontal cortex of awake rats in response to a single peripheral or central administration of dexfenfluramine.
Topics: Animals; Aspartic Acid; Consciousness; Dose-Response Relationship, Drug; Electrophoresis, Capillary; Excitatory Amino Acids; Extracellular Space; Fenfluramine; Fluorescent Dyes; Frontal Lobe; gamma-Aminobutyric Acid; Glutamic Acid; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Lasers; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Agents | 1996 |
Effects of repeated oral doses of dexnorfenfluramine on 5-HT levels and 5-HT uptake sites in rat brain.
Topics: Administration, Oral; Animals; Brain; Citalopram; Fenfluramine; Hydroxyindoleacetic Acid; Male; Rats; Serotonin | 1996 |
The spin trap reagent PBN attenuates degeneration of 5-HT neurones in rat brain induced by p-chloroamphetamine but not fenfluramine.
Topics: Animals; Body Temperature; Brain; Brain Chemistry; Cyclic N-Oxides; Fenfluramine; Hydroxyindoleacetic Acid; Male; Nerve Degeneration; Neurons; Nitrogen Oxides; p-Chloroamphetamine; Paroxetine; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Spin Labels; Spin Trapping | 1996 |
Administration of fenfluramine at different ambient temperatures produces different core temperature and 5-HT neurotoxicity profiles.
Topics: Animals; Body Temperature Regulation; Brain; Brain Chemistry; Cell Death; Fenfluramine; Fever; Hydroxyindoleacetic Acid; Neurons; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Temperature; Time Factors | 1997 |
The effect of D-fenfluramine on brain 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in male and female rats.
Topics: Animals; Brain Chemistry; Female; Fenfluramine; Hydroxyindoleacetic Acid; Male; Norfenfluramine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Sex Characteristics | 1997 |
Central serotonin activity and aggression: inverse relationship with prolactin response to d-fenfluramine, but not CSF 5-HIAA concentration, in human subjects.
Topics: Adult; Aggression; Brain; Female; Fenfluramine; Humans; Hydroxyindoleacetic Acid; Male; Personality Disorders; Prolactin; Psychiatric Status Rating Scales; Serotonin; Violence | 1997 |
p-Chloroamphetamine- and d-fenfluramine-induced brain serotonin release in experimental portal-systemic encephalopathy.
Topics: Animals; Brain; Cerebral Cortex; Extracellular Space; Fenfluramine; Hepatic Encephalopathy; Hydroxyindoleacetic Acid; Male; Osmolar Concentration; p-Chloroamphetamine; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Agents | 1997 |
Valvular heart disease associated with fenfluramine-phentermine.
Topics: Appetite Depressants; Diabetes Mellitus, Type 2; Drug Combinations; Female; Fenfluramine; Heart Valve Diseases; Humans; Hydroxyindoleacetic Acid; Phentermine; Serotonin | 1997 |
Fenfluramine and norfenfluramine levels in brain microdialysate, brain tissue and plasma of rats administered doses of d-fenfluramine known to deplete 5-hydroxytryptamine levels in brain.
Topics: Animals; Body Temperature; Brain; Cerebral Cortex; Dialysis; Dose-Response Relationship, Drug; Fenfluramine; Hydroxyindoleacetic Acid; Male; Norfenfluramine; Rats; Rats, Sprague-Dawley; Serotonin | 1998 |
The effect of fenfluramine dosage regimen and reduced food intake on levels of 5-HT in rat brain.
Topics: Animals; Body Weight; Brain Chemistry; Dose-Response Relationship, Drug; Eating; Fenfluramine; Hydroxyindoleacetic Acid; Male; Norfenfluramine; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin | 1997 |
Dietary fat type influences protein consumption in rats given 8-hydroxy-2-(Di-n-propylamino)tetralin.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Corn Oil; Dietary Fats; Dietary Proteins; Fats; Fenfluramine; Food Preferences; Hydroxyindoleacetic Acid; Male; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Receptor Agonists | 1998 |
In vivo correlates of central serotonin function after high-dose fenfluramine administration.
Topics: Animals; Behavior, Animal; Brain; Corticosterone; Dose-Response Relationship, Drug; Fenfluramine; Hydroxyindoleacetic Acid; Male; Prolactin; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Agents; Time Factors | 1998 |
Reversal of fenfluramine and fluoxetine anorexia by 8-OH-DPAT is attenuated following raphe injection of 5,7-dihydroxytryptamine.
Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anorexia; Brain; Corpus Striatum; Dopamine; Feeding Behavior; Fenfluramine; Fluoxetine; Hippocampus; Hydroxyindoleacetic Acid; Hypothalamus; Infusions, Parenteral; Male; Neurotoxins; Norepinephrine; Piperazines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Receptor Agonists | 1998 |
Cerebrospinal fluid vasopressin levels: correlates with aggression and serotonin function in personality-disordered subjects.
Topics: Adult; Aggression; Arginine Vasopressin; Female; Fenfluramine; Humans; Hydroxyindoleacetic Acid; Impulsive Behavior; Male; Mental Disorders; Personality Disorders; Prolactin; Psychiatric Status Rating Scales; Serotonin | 1998 |
Neurotoxic effects of +/-fenfluramine and phenteramine, alone and in combination, on monoamine neurons in the mouse brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Appetite Depressants; Biogenic Monoamines; Body Weight; Brain; Dopamine; Drinking Behavior; Drug Interactions; Energy Intake; Feeding Behavior; Fenfluramine; Hydroxyindoleacetic Acid; Male; Mice; Neurons; Neurotoxins; Phentermine; Serotonin | 1998 |
Effects of antihistamines on fenfluramine-induced depletion of indoles in the brain of rats.
Topics: Animals; Biomarkers; Body Temperature; Body Weight; Brain; Chlorpheniramine; Drug Interactions; Fenfluramine; Histamine H1 Antagonists; Hydroxyindoleacetic Acid; Male; Rats; Rats, Sprague-Dawley; Serotonin | 1999 |
Hyperthermia-enhanced serotonin (5-HT) depletion resulting from D-fenfluramine (D-Fen) exposure does not evoke a glial-cell response in the central nervous system of rats.
Topics: Animals; Brain Chemistry; Fenfluramine; Fever; Frontal Lobe; Glial Fibrillary Acidic Protein; Gliosis; Hippocampus; Hydroxyindoleacetic Acid; Male; Neuroglia; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin | 1999 |
Effects of fenfluramine combined with electroacupuncture on monoamine release in periaqueductal gray of rat brain.
Topics: Animals; Biogenic Monoamines; Electroacupuncture; Fenfluramine; Hydroxyindoleacetic Acid; Male; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Agents | 1999 |
Characterization of D-fenfluramine-induced hypothermia: evidence for multiple sites of action.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Benzofurans; Body Temperature; Cerebral Cortex; Dopamine Antagonists; Dose-Response Relationship, Drug; Fenclonine; Fenfluramine; Haloperidol; Hydroxyindoleacetic Acid; Hypothalamus; Hypothermia; Ketanserin; Male; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Sertraline; Sulpiride; Yohimbine | 2000 |
The effect of fenfluramine on the pulmonary disposition of 5-hydroxytryptamine in the isolated perfused rat lung: a comparison with chlorphentermine.
Topics: Animals; Chlorphentermine; Chromatography, Liquid; Female; Fenfluramine; Free Radical Scavengers; Hydroxyindoleacetic Acid; Lung; Metabolic Clearance Rate; Perfusion; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Sympathomimetics | 2000 |
Long-term impairment of anterograde axonal transport along fiber projections originating in the rostral raphe nuclei after treatment with fenfluramine or methylenedioxymethamphetamine.
Topics: 5,7-Dihydroxytryptamine; Adrenergic Uptake Inhibitors; Animals; Axonal Transport; Axons; Desipramine; Fenfluramine; Hydroxyindoleacetic Acid; Male; Monoamine Oxidase Inhibitors; N-Methyl-3,4-methylenedioxyamphetamine; Neural Pathways; Neurotoxins; Pargyline; Proline; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Time Factors; Tritium | 2001 |
1-(m-chlorophenyl)piperazine (mCPP) dissociates in vivo serotonin release from long-term serotonin depletion in rat brain.
Topics: Animals; Brain; Carrier Proteins; Caudate Nucleus; Cerebral Cortex; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Fenfluramine; Hydroxyindoleacetic Acid; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; Nerve Tissue Proteins; Neurons; Nucleus Accumbens; Piperazines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Time Factors; Tritium | 2001 |
Effects of dietary sucrose on hippocampal serotonin release: a microdialysis study in the freely-moving rat.
Topics: Animals; Dietary Carbohydrates; Dietary Sucrose; Dopamine; Fenfluramine; gamma-Aminobutyric Acid; Hippocampus; Hydroxyindoleacetic Acid; Male; Microdialysis; Rats; Rats, Wistar; Serotonin; Serotonin Agents | 2001 |
Effects of fenfluramine, m-CPP and triazolam on repeated-acquisition in squirrel monkeys before and after neurotoxic MDMA administration.
Topics: Animals; Behavior, Animal; Brain; Dose-Response Relationship, Drug; Fenfluramine; GABA Modulators; Hydroxyindoleacetic Acid; Learning; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Reaction Time; Saimiri; Serotonin; Serotonin Agents; Serotonin Receptor Agonists; Triazolam | 2002 |
Depletion of 5-HT disrupts prepulse inhibition in rats: dependence on the magnitude of depletion, and reversal by a 5-HT precursor.
Topics: 5-Hydroxytryptophan; Animals; Drug Combinations; Fenclonine; Fenfluramine; Hippocampus; Hydroxyindoleacetic Acid; Male; Rats; Rats, Sprague-Dawley; Reflex, Startle; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists | 2002 |
Role of monoamine oxidase inhibition and monoamine depletion in fenfluramine-induced neurotoxicity and serotonin release.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Clorgyline; Corpus Striatum; Dopamine; Drug Interactions; Fenclonine; Fenfluramine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Monoamine Oxidase Inhibitors; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Selegiline; Serotonin; Serotonin Antagonists; Tryptophan | 2001 |
Brain serotonin and the control of food intake in rainbow trout (Oncorhynchus mykiss): effects of changes in plasma glucose levels.
Topics: Animals; Blood Glucose; Eating; Fenfluramine; Glucose; Hydroxyindoleacetic Acid; Hypoglycemic Agents; Hypothalamus; Insulin; Oncorhynchus mykiss; Serotonin; Serotonin Agents; Telencephalon | 2002 |
Effect of glucoprivation on serotonin neurotoxicity induced by substituted amphetamines.
Topics: Amphetamines; Animals; Antimetabolites; Biogenic Monoamines; Body Temperature; Carrier Proteins; Deoxyglucose; Energy Metabolism; Fenfluramine; Glucose; Hydroxyindoleacetic Acid; Male; Membrane Glycoproteins; Membrane Transport Proteins; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Degeneration; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins | 2002 |
Positron emission tomography of regional brain metabolic responses to a serotonergic challenge and lethality of suicide attempts in major depression.
Topics: Adult; Age Factors; Brain; Depressive Disorder; Female; Fenfluramine; Fluorodeoxyglucose F18; Glucose; Humans; Hydroxyindoleacetic Acid; Impulsive Behavior; Male; Prefrontal Cortex; Prolactin; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Suicide, Attempted; Tissue Distribution; Tomography, Emission-Computed | 2003 |
Cigarette smoking, suicidal behavior, and serotonin function in major psychiatric disorders.
Topics: Adolescent; Adult; Aged; Comorbidity; Depressive Disorder; Female; Fenfluramine; Humans; Hydrocortisone; Hydroxyindoleacetic Acid; Male; Mental Disorders; Middle Aged; Prolactin; Schizophrenia; Serotonin; Serotonin Agents; Smoking; Smoking Cessation; Smoking Prevention; Suicide; Suicide, Attempted | 2003 |
High-dose fenfluramine administration decreases serotonin transporter binding, but not serotonin transporter protein levels, in rat forebrain.
Topics: Animals; Blotting, Western; Carrier Proteins; Fenfluramine; Hydroxyindoleacetic Acid; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; p-Chloroamphetamine; Prosencephalon; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins | 2003 |
Cerebrospinal fluid monoamine and metabolite concentrations and aggression in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5,7-Dihydroxytryptamine; Aggression; Animals; Biogenic Monoamines; Chromatography, High Pressure Liquid; Dopamine; Fenfluramine; Hydroxyindoleacetic Acid; Male; Norepinephrine; Piperazines; Pyridines; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2003 |
Metyrapone attenuates the sequential learning deficits but not monoamine depletions following d,l-fenfluramine administration to adult rats.
Topics: Adrenal Glands; Age Factors; Animals; Biogenic Monoamines; Body Temperature; Body Weight; Enzyme Inhibitors; Fenfluramine; Hydroxyindoleacetic Acid; Hypothalamus; Learning Disabilities; Male; Maze Learning; Metyrapone; Norepinephrine; Organ Size; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Swimming; Thymus Gland | 2004 |
Prenatal 3,4-methylenedioxymethamphetamine (ecstasy) exposure induces long-term alterations in the dopaminergic and serotonergic functions in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Adrenergic Uptake Inhibitors; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Autoradiography; Brain; Brain Chemistry; Dopamine; Embryo, Mammalian; Female; Fenfluramine; Hallucinogens; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Membrane Transport Proteins; Microdialysis; Nortropanes; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Sex Factors; Time Factors; Tyramine | 2005 |
Permanent deficits in serotonergic functioning of olfactory bulbectomized rats: an in vivo microdialysis study.
Topics: Animals; Area Under Curve; Behavior, Animal; Body Weight; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Dopamine; Electrochemistry; Enzyme Inhibitors; Exploratory Behavior; Fenfluramine; Fluvoxamine; Hydrazines; Hydroxyindoleacetic Acid; Male; Microdialysis; Multivariate Analysis; Olfaction Disorders; Olfactory Bulb; Olfactory Pathways; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Time Factors | 2005 |
Central serotonin depletion affects rat brain areas differently: a qualitative and quantitative comparison between different treatment schemes.
Topics: Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Drug Administration Schedule; Drug Interactions; Fenfluramine; Hydroxyindoleacetic Acid; Male; p-Chloroamphetamine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents | 2006 |
Serotonin depletion results in a decrease of the neuronal activation caused by rivastigmine in the rat hippocampus.
Topics: Acetylcholine; Animals; Cell Count; Chromatography, High Pressure Liquid; Drug Interactions; Fenclonine; Fenfluramine; Gene Expression; Hippocampus; Hydroxyindoleacetic Acid; Immunohistochemistry; Male; Neurons; Neuroprotective Agents; Phenylcarbamates; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Rivastigmine; Selective Serotonin Reuptake Inhibitors; Serotonin | 2006 |
Peripheral serotonin dynamics in the rainbow trout (Oncorhynchus mykiss).
Topics: Animals; Fenfluramine; Gills; Hydroxyindoleacetic Acid; Intestinal Mucosa; Intestines; Kidney; Liver; Myocardium; Oncorhynchus mykiss; Serotonin; Serotonin Agents; Spleen | 2007 |
Estrogen receptor (ER) subtype agonists alter monoamine levels in the female rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Cerebral Cortex; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Fenfluramine; Fluorenes; Hippocampus; Hydroxyindoleacetic Acid; Methoxyhydroxyphenylglycol; Norepinephrine; Ovariectomy; Phenols; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Estrogen | 2010 |
Deficient serotonin neurotransmission and depression-like serotonin biomarker alterations in tryptophan hydroxylase 2 (Tph2) loss-of-function mice.
Topics: Animals; Behavior, Animal; Biomarkers; Corticosterone; Depression; Disease Models, Animal; Extracellular Fluid; Female; Fenfluramine; Frontal Lobe; Gene Knock-In Techniques; Hippocampus; Hydroxyindoleacetic Acid; Hypothermia; Male; Mice; Mice, Inbred C57BL; Prolactin; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Serotonergic Neurons; Serotonin; Serotonin 5-HT1 Receptor Agonists; Synaptic Transmission; Tryptophan Hydroxylase | 2012 |
Polyunsaturated fatty acid associations with dopaminergic indices in major depressive disorder.
Topics: Adult; Aged; Analysis of Variance; Antidepressive Agents; Depressive Disorder, Major; Fatty Acids, Unsaturated; Female; Fenfluramine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Prolactin; Psychiatric Status Rating Scales; Regression Analysis; Young Adult | 2014 |
Serotonin release in the caudal nidopallium of adult laying hens genetically selected for high and low feather pecking behavior: an in vivo microdialysis study.
Topics: Animals; Behavior, Animal; Blood Chemical Analysis; Brain; Chickens; Feathers; Female; Fenfluramine; Hydroxyindoleacetic Acid; Microdialysis; Serotonin; Serotonin Agents; Species Specificity; Tryptophan | 2014 |