hydroxyindoleacetic acid and clozapine

hydroxyindoleacetic acid has been researched along with clozapine in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199010 (34.48)18.7374
1990's13 (44.83)18.2507
2000's5 (17.24)29.6817
2010's1 (3.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Ackenheil, M; von Stralendorff, B; Zimmermann, J1
Banki, CM1
Banki, CM; Vojnik, M1
Fog, R; Gerlach, J; Thorsen, K1
Ackenheil, M; Blatt, B; Lampart, C1
Asper, H; Bürki, HR; Ruch, W2
Marsden, CA; Rivest, R1
Gutierrez, R; Konicki, E; Litman, RE; Owen, RR; Pickar, D; Rapaport, MH1
Chen, J; Gardner, EL; Paredes, W; van Praag, HM1
Chai, B; Meltzer, HY1
Ichikawa, J; Meltzer, HY1
Barrett, JE; Harrod, C; Hoffmann, SM; Lei, Z; Mansbach, RS; Nader, MA; Witkin, JM1
Cooper, T; Johns, C; Kane, J; Lieberman, J; Pollack, S1
Blakely, RD; Herndon, JG; Justice, JB; Neill, DB; Wages, SA1
Hsiao, JK; Litman, RE; Owen, RR; Pickar, D; Su, TP1
Cooper, T; Kane, J; Kronig, M; Lieberman, J; Munne, R; Pollack, S; Safferman, A; Szymanski, S1
Risch, SC1
Lewine, RR; Risch, SC1
Burnet, PW; Chen, CP; Franklin, M; Harrison, PJ; McGowan, S1
Frazier, JA; Gordon, CT; Hamburger, SD; Jacobsen, LK; Karoum, F; Lenane, MC; Malhotra, AK; McKenna, K; Pickar, D; Potter, WZ; Rapoport, JL1
Hertel, P; Nomikos, GG; Svensson, TH1
Hatzimanolis, J; Lykouras, L; Markianos, M; Oulis, P1
Cartmell, J; Monn, JA; Perry, KW; Salhoff, CR; Schoepp, DD3
Banjaw, MY; Fendt, M; Schmidt, WJ1
Batool, F; Haleem, DJ; Haleem, MA; Hasnat, A1

Trials

4 trial(s) available for hydroxyindoleacetic acid and clozapine

ArticleYear
Extrapyramidal reactions and amine metabolites in cerebrospinal fluid during haloperidol and clozapine treatment of schizophrenic patients.
    Psychopharmacologia, 1975, Volume: 40, Issue:4

    Topics: Adult; Aged; Basal Ganglia Diseases; Clinical Trials as Topic; Clozapine; Dibenzazepines; Haloperidol; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Movement Disorders; Parkinson Disease, Secondary; Phenylacetates; Schizophrenia

1975
Clinical and biologic response to clozapine in patients with schizophrenia. Crossover comparison with fluphenazine.
    Archives of general psychiatry, 1992, Volume: 49, Issue:5

    Topics: Adult; Antipsychotic Agents; Clozapine; Dopamine; Double-Blind Method; Female; Fluphenazine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Placebos; Schizophrenia; Schizophrenic Psychology; Serotonin

1992
Predictors of clozapine response in schizophrenia.
    The Journal of clinical psychiatry, 1994, Volume: 55 Suppl B

    Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Clozapine; Double-Blind Method; Female; Fluphenazine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Probability; Receptors, Neurotransmitter; Schizophrenia; Treatment Outcome

1994
The dopamine-serotonin relationship in clozapine response.
    Psychopharmacology, 1993, Volume: 112, Issue:1 Suppl

    Topics: Adolescent; Adult; Antipsychotic Agents; Clozapine; Dopamine; Drug Resistance; Dyskinesia, Drug-Induced; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Psychiatric Status Rating Scales; Schizophrenia; Serotonin

1993

Other Studies

25 other study(ies) available for hydroxyindoleacetic acid and clozapine

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
[Acute and chronic effects of carpipramine, clozapine, haloperidol and sulpiride on the metabolism of biogenic amines in the rat brain (author's transl)].
    Arzneimittel-Forschung, 1976, Volume: 26, Issue:6

    Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Biogenic Amines; Brain; Brain Chemistry; Cerebral Cortex; Clozapine; Corpus Striatum; Dibenzazepines; Haloperidol; Homovanillic Acid; Hydroxyindoleacetic Acid; Limbic System; Male; Methoxyhydroxyphenylglycol; Rats; Sulpiride

1976
Alterations of cerebrospinal fluid 5-hydroxyindoleacetic acid, and total blood serotonin content during clozapine treatment.
    Psychopharmacology, 1978, Mar-01, Volume: 56, Issue:2

    Topics: Adult; Clozapine; Dibenzazepines; Female; Humans; Hydroxyindoleacetic Acid; Leukocyte Count; Middle Aged; Psychotic Disorders; Serotonin; Time Factors

1978
Comparative simultaneous measurement of cerebrospinal fluid 5-hydroxyindoleacetic acid and blood serotonin levels in delirium tremens and clozapine-induced delirious reaction.
    Journal of neurology, neurosurgery, and psychiatry, 1978, Volume: 41, Issue:5

    Topics: Adult; Alcohol Withdrawal Delirium; Clozapine; Delirium; Dibenzazepines; Female; Humans; Hydroxyindoleacetic Acid; Psychoses, Alcoholic; Schizophrenia; Serotonin

1978
Effect of clozapine on 5-HIAA excretion in urine and CSF of psychotic patients and on serotonin metabolism in rat brain.
    Acta vitaminologica et enzymologica, 1975, Volume: 29, Issue:1-6

    Topics: Animals; Brain; Circadian Rhythm; Clozapine; Dibenzazepines; Humans; Hydroxyindoleacetic Acid; Male; Psychotic Disorders; Rats; Serotonin; Sleep Stages

1975
Effect of clozapine on the metabolism of serotonin in rat brain.
    Acta vitaminologica et enzymologica, 1975, Volume: 29, Issue:1-6

    Topics: Animals; Brain; Brain Stem; Clozapine; Dibenzazepines; Hydroxyindoleacetic Acid; Rats; Serotonin; Tryptophan

1975
Effect of clozapine on the metabolism of serotonin in rat brain.
    Psychopharmacologia, 1976, Volume: 46, Issue:1

    Topics: Animals; Brain; Brain Stem; Clozapine; Dibenzazepines; Haloperidol; Hydroxyindoleacetic Acid; Limbic System; Loxapine; Male; Rats; Serotonin; Thioridazine; Tryptophan; Tryptophan Hydroxylase

1976
Differential effects of amfonelic acid on the haloperidol- and clozapine-induced increase in extracellular DOPAC in the nucleus accumbens and the striatum.
    Synapse (New York, N.Y.), 1992, Volume: 10, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Clozapine; Corpus Striatum; Drug Interactions; Haloperidol; Hydroxyindoleacetic Acid; Kinetics; Male; Membrane Potentials; Nalidixic Acid; Naphthyridines; Nucleus Accumbens; Rats; Rats, Inbred Strains; Ritanserin; Time Factors

1992
Serotonin denervation enhances responsiveness of presynaptic dopamine efflux to acute clozapine in nucleus accumbens but not in caudate-putamen.
    Brain research, 1992, Jun-05, Volume: 582, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Caudate Nucleus; Clozapine; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Nucleus Accumbens; Putamen; Rats; Rats, Inbred Strains; Serotonin Antagonists; Synapses; Time Factors

1992
The effect of chronic clozapine on basal dopamine release and apomorphine-induced DA release in the striatum and nucleus accumbens as measured by in vivo brain microdialysis.
    Neuroscience letters, 1992, Jun-08, Volume: 140, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Clozapine; Corpus Striatum; Dialysis; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Kinetics; Male; Nucleus Accumbens; Rats; Rats, Wistar; Reference Values; Time Factors

1992
Differential effects of repeated treatment with haloperidol and clozapine on dopamine release and metabolism in the striatum and the nucleus accumbens.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Clozapine; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Tolerance; Extracellular Space; Haloperidol; Hydroxyindoleacetic Acid; Injections, Subcutaneous; Male; Nucleus Accumbens; Rats; Rats, Inbred Strains

1991
Behavioral studies with anxiolytic drugs. V. Behavioral and in vivo neurochemical analyses in pigeons of drugs that increase punished responding.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Anti-Anxiety Agents; Buspirone; Chlordiazepoxide; Clozapine; Columbidae; Conditioning, Operant; Haloperidol; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Punishment; Pyrimidines

1988
Clozapine pharmacology and tardive dyskinesia.
    Psychopharmacology, 1989, Volume: 99 Suppl

    Topics: Adolescent; Adult; Clozapine; Dibenzazepines; Dyskinesia, Drug-Induced; Epinephrine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Phenethylamines; Prolactin; Schizophrenia

1989
Neuroleptics increase striatal catecholamine metabolites but not ascorbic acid in dialyzed perfusate.
    Brain research, 1984, Aug-06, Volume: 308, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Ascorbic Acid; Catecholamines; Catheterization; Clozapine; Corpus Striatum; Dibenzazepines; Haloperidol; Homovanillic Acid; Hydroxyindoleacetic Acid; Kinetics; Male; Perfusion; Rats; Rats, Inbred Strains

1984
Clozapine therapy and increases in homovanillic acid.
    Archives of general psychiatry, 1995, Volume: 52, Issue:3

    Topics: Chromatography, High Pressure Liquid; Clozapine; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Psychiatric Status Rating Scales; Schizophrenia; Serotonin; Treatment Outcome

1995
Low cerebrospinal fluid homovanillic acid-5-hydroxyindoleacetic acid ratio predicts clozapine efficacy: a replication.
    Archives of general psychiatry, 1993, Volume: 50, Issue:8

    Topics: Clozapine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Prospective Studies; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology

1993
The effects of clozapine and haloperidol on serotonin-1A, -2A and -2C receptor gene expression and serotonin metabolism in the rat forebrain.
    Neuroscience, 1996, Volume: 73, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Cerebral Cortex; Clozapine; Corpus Striatum; Haloperidol; Hippocampus; Hydroxyindoleacetic Acid; In Situ Hybridization; Ketanserin; Male; Organ Specificity; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reference Values; RNA, Messenger; Serotonin; Transcription, Genetic; Tritium

1996
Cerebrospinal fluid monoamine metabolites in childhood-onset schizophrenia.
    The American journal of psychiatry, 1997, Volume: 154, Issue:1

    Topics: Adolescent; Age of Onset; Child; Clozapine; Haloperidol; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methoxyhydroxyphenylglycol; Neurotransmitter Agents; Prolactin; Schizophrenia, Childhood; Treatment Outcome

1997
Risperidone inhibits 5-hydroxytryptaminergic neuronal activity in the dorsal raphe nucleus by local release of 5-hydroxytryptamine.
    British journal of pharmacology, 1997, Volume: 122, Issue:8

    Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Clozapine; Dopamine Antagonists; Hydroxyindoleacetic Acid; Idazoxan; Male; Piperazines; Prazosin; Pyridines; Raclopride; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Serotonin; Risperidone; Salicylamides; Serotonin; Serotonin Antagonists

1997
Neurochemical variables in schizophrenic patients during switching from neuroleptics to clozapine.
    Progress in neuro-psychopharmacology & biological psychiatry, 1998, Volume: 22, Issue:7

    Topics: Adolescent; Adult; Antipsychotic Agents; Chlorpromazine; Clozapine; Homovanillic Acid; Humans; Hydrocortisone; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Middle Aged; Prolactin; Regression Analysis; Schizophrenia

1998
The potent, selective mGlu2/3 receptor agonist LY379268 increases extracellular levels of dopamine, 3,4-dihydroxyphenylacetic acid, homovanillic acid, and 5-hydroxyindole-3-acetic acid in the medial prefrontal cortex of the freely moving rat.
    Journal of neurochemistry, 2000, Volume: 75, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acids; Animals; Bridged Bicyclo Compounds, Heterocyclic; Clozapine; Dopamine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Homovanillic Acid; Hydroxyindoleacetic Acid; Kinetics; Male; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Xanthenes

2000
Dopamine and 5-HT turnover are increased by the mGlu2/3 receptor agonist LY379268 in rat medial prefrontal cortex, nucleus accumbens and striatum.
    Brain research, 2000, Dec-29, Volume: 887, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acids; Animals; Bridged Bicyclo Compounds, Heterocyclic; Clozapine; Corpus Striatum; Dopamine; Excitatory Amino Acid Agonists; Homovanillic Acid; Hydroxyindoleacetic Acid; Kinetics; Male; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Risperidone; Serotonin

2000
Acute increases in monoamine release in the rat prefrontal cortex by the mGlu2/3 agonist LY379268 are similar in profile to risperidone, not locally mediated, and can be elicited in the presence of uptake blockade.
    Neuropharmacology, 2001, Volume: 40, Issue:7

    Topics: Amino Acids; Animals; Biogenic Monoamines; Bridged Bicyclo Compounds, Heterocyclic; Clozapine; Dopamine; Dopamine Antagonists; Excitatory Amino Acid Agonists; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Risperidone; Serotonin; Serotonin Antagonists

2001
Clozapine attenuates the locomotor sensitisation and the prepulse inhibition deficit induced by a repeated oral administration of Catha edulis extract and cathinone in rats.
    Behavioural brain research, 2005, May-28, Volume: 160, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Methoxytryptamine; Alkaloids; Analysis of Variance; Animals; Behavior, Animal; Brain Chemistry; Catha; Clozapine; Dopamine; Drug Interactions; Homovanillic Acid; Hydroxyindoleacetic Acid; Inhibition, Psychological; Male; Motor Activity; Psychotropic Drugs; Rats; Rats, Sprague-Dawley; Reflex, Acoustic; Serotonin

2005
Dose-related effects of clozapine and risperidone on the pattern of brain regional serotonin and dopamine metabolism and on tests related to extrapyramidal functions in rats.
    Acta pharmaceutica (Zagreb, Croatia), 2010, Volume: 60, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Behavior; Brain; Clozapine; Corpus Striatum; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Extrapyramidal Tracts; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Motor Activity; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Dopamine D2; Risperidone; Serotonin; Serotonin Antagonists; Tryptophan; Visual Cortex

2010