hydroxyindoleacetic acid and 8-hydroxy-2-(di-n-propylamino)tetralin

hydroxyindoleacetic acid has been researched along with 8-hydroxy-2-(di-n-propylamino)tetralin in 116 studies

Research

Studies (116)

TimeframeStudies, this research(%)All Research%
pre-199020 (17.24)18.7374
1990's63 (54.31)18.2507
2000's27 (23.28)29.6817
2010's5 (4.31)24.3611
2020's1 (0.86)2.80

Authors

AuthorsStudies
Barrett, JE; Gleeson, S; Seggel, MR; Weissman, BA1
Burnet, PW; Gold, PW; Mefford, IN; Smith, CC; Sternberg, EM1
Grahame-Smith, DG; Wang, H1
Hjorth, S; Tao, R1
Barnes, NM; Cheng, CH; Costall, B; Ge, J; Naylor, RJ1
Baudrie, V; Broqua, P; Chaouloff, F; Zamfir, O1
Baba, A; Matsuda, T; Nakano, Y; Takuma, K; Yoshikawa, T1
Curzon, G; Haleem, DJ; Kennett, GA1
Beer, M; Curzon, G; Kennett, GA1
Angeby-Möller, K; Larsson, LG; Rényi, L; Ross, SB; Svensson, B1
Cross, AJ; Davies, EM; DeSouza, RJ; Green, AR1
Hjorth, S; Liu, Y; Sharp, T1
Baba, A; Iwata, H; Kanda, T; Matsuda, T; Seong, YH1
Anderson, JM; Balfour, DJ; Benwell, ME1
Kreider, MS; Lucki, I; McGonigle, P; Wieland, S1
Kidd, EJ; Leysen, JE; Marsden, CA1
Bolaños, FJ; Fattaccini, CM; Gozlan, H; Haj-Dahmane, S; Hamon, M; Lanfumey, L; Laporte, AM; Schechter, LE1
Croissant, D; Eckols, K; Stewart, G; Uphouse, L1
Crespi, F; Garratt, JC; Marsden, CA; Mason, R1
Auerbach, SB; Jacobs, BL; Wilkinson, LO1
Marsden, CA; Routledge, C1
Bowen, DM; Edel, N; Middlemiss, DN; Palmer, AM1
Bendotti, C; Garattini, S; Invernizzi, R; Mennini, T; Samanin, R1
Curzon, G; Dourish, CT; Hutson, PH2
Marsden, CA; Martin, KF1
Ciesielski, L; Gobaille, S; Isel, F; Mandel, P; Molina, V1
Curzon, G; Dourish, CT; Kennett, GA; Marcou, M1
Gietzen, DW; Leung, PM; Piechota, T; Rogers, QR; Semon, B1
Fuller, RW; Snoddy, HD1
Chaouloff, F; Elghozi, JL; Laude, D; Mérino, D; Serrurrier, B1
Bramwell, SR; Grahame-Smith, DG; Sharp, T1
Bradbury, AJ; Higgins, GA; Jones, BJ; Oakley, NR1
Hjorth, S; Magnusson, T1
Bramwell, SR; Clark, D; Grahame-Smith, DG; Sharp, T1
Barrett, JE; Nader, MA1
Curzon, G; Hutson, PH; O'Connell, MT; Sarna, GS1
Goodwin, GM; Green, AR1
Artaud, F; Bourgoin, S; Goetz, C; Gozlan, H; Hall, MD; Hamon, M; Horn, AS1
Arbogast, R; Palfreyman, MG; Wagner, J; Zreika, M1
Fiorella, D; Johnson, RG; Rabin, RA1
Cortizo, L; Hacksell, U; Lewander, T; Liu, Y; Svensson, BE; Yu, H1
Cheng, CH; Costall, B; Ge, J; Naylor, RJ1
Akiyoshi, J; Kuranaga, H; Mizobe, Y; Nagayama, H; Nakamura, M; Tsuchiyama, K1
Aguilar, E; Aguilar, R; Pinilla, L; Ranchal, A1
Davies, RO; Kubin, L; Pack, AI; Reignier, C; Taguchi, O; Tojima, H1
Saphier, D; Welch, JE1
Kelly, JP; Leonard, BE1
Gower, AJ; Kendall, DA; Marsden, CA; Robson, L1
Jantos, H; Monti, JM; Prunell, G; Reyes-Parada, M; Scorza, C; Silveira, R1
Handley, SL; McBlane, JW1
Maswood, S; Stewart, G; Uphouse, L1
Kreiss, DS; Lucki, I; Wieland, S1
Adell, A; Artigas, F; Carceller, A1
Auerbach, SB; Rutter, JJ1
Adrien, J; Fattaccini, CM; Gozlan, H; Guardiola-Lemaitre, B; Haj-Dahmane, S; Hamon, M; Jolas, T; Kidd, EJ; Lanfumey, L1
Hacksell, U; Hjorth, S; Höök, BB; Johansson, AM; Sundell, S1
Clement, HW; Gemsa, D; Ruwe, C; Schäfer, F; Wesemann, W1
Lima, L; Salazar, M; Trejo, E1
Baudrie, V; Bluet-Pajot, MT; Broqua, P; Chaouloff, F; Laude, D; Schmidt, B1
Curzon, G; Datla, KP1
Pan, JT; Yang, IC1
Fangon, NB; Frazer, A; Thielen, RJ1
Barf, T; Bohus, B; Damsma, G; Korte, SM; Korte-Bouws, G; Sonesson, C; Wikström, H1
Butterworth, RF; Mousseau, DD; Rao, VL1
Burnet, PW; Chen, CP; Franklin, M; Harrison, PJ; McGowan, S1
Cassel, JC; Jackisch, R; Jeltsch, H; Lauth, D; Neufang, B; Szabo, B1
Arborelius, L; Hacksell, U; Höök, BB; Nomikos, GG; Svensson, TH1
McMahon, LR; Wellman, PJ1
Clarke, T; Rollema, H; Schulz, DW; Sprouse, JS1
Afkhami-Dastjerdian, S; Carli, M; Reader, TA1
Aguerre, S; Berton, O; Chaouloff, F; Kulikov, A; Mormede, P; Ramos, A1
Dall' Olio, R; Gaggi, R; Roncada, P; Santangelo, M1
Javaid, J; Shim, I; Wirtshafter, D1
Edwards, GL; Grossman, BM; Hobbs, JK; Martin, RJ1
Cano, J; Machado, A; Matarredona, ER; Santiago, M1
Aguirre, N; Ballaz, S; Del Río, J; Lasheras, B1
Coscina, DV; Currie, PJ; Fletcher, PJ1
Haapalinna, A; Koivisto, E; MacDonald, E; Riekkinen, P; Ruotsalainen, S; Sirviö, J; Stefanski, R1
Akiyama, M; Ikeda, M; Moriya, T; Shibata, S; Yokota, S; Yoshinobu, Y1
Connor, TJ; Dredge, K; Harkin, A; Kelly, JP; Leonard, BE; McNamara, M; Redmond, A1
Cremer, H; Delling, M; Hoyer, D; Schachner, M; Stork, O; Welzl, H; Wotjak, CT1
Kaehler, ST; Philippu, A; Singewald, N1
Kunitomo, M; Sugimoto, Y; Yamada, J1
Chiavegatto, S; Dawson, TM; Dawson, VL; Koliatsos, VE; Mamounas, LA; Nelson, RJ1
Borostyánkoi, ZA; Görcs, TJ; Harkany, T; Keijser, J; Kelly, JP; Kónya, C; Leonard, BE; Luiten, PG; O'Mahony, S; Penke, B; Zarándi, M1
Allikmets, L; Matto, V; Pruus, K; Rudissaar, R; Vaarmann, A1
Body, S; Bradshaw, CM; Chiang, TJ; Ho, MY; Mobini, S; Szabadi, E1
Mignon, L; Wolf, WA1
Borszcz, GS; Munn, EM1
Chocyk, A; Czyrak, A; Fijał, K; Gadek-Michalska, A; Maćkowiak, M; Wedzony, K1
Carreira, I; Fajardo, O; Galeno, J; Lima, L; Urbina, M1
Karamanakos, PN; Marselos, M; Pappas, P1
Kamei, J; Matsunawa, Y; Miyata, S; Saitoh, A; Tanaka, S1
Bert, B; Carey, RJ; De Souza Silva, MA; Fink, H; Huston, JP; Müller, CP; Thönnessen, H1
Aihara, Y; Hasegawa, H; Ishiwata, T; Otokawa, M; Saito, T; Yazawa, T1
Bozdayi, AM; Bozkaya, H; Celik, T; Cinar, K; Gören, MZ; Gürdal, H; Onder, FO; Tan, A; Terzioğlu, B; Uzunalimoğlu, O; Yurdaydin, C1
Benhamú, B; Caicoya, AG; Delgado, M; Fernández-Alfonso, MS; Fuentes, JA; Greciano, V; López-Rodríguez, ML; Manzanares, J; Pozo, MA1
Bandoh, T; Hayashi, M; Hoshi, K; Iwamasa, K; Shindome, N; Shirai, Y1
Haleem, DJ; Khan, A1
Haider, S; Haleem, DJ; Haleem, MA; Perveen, T; Samad, N1
Haleem, DJ; Haleem, MA; Samad, N2
Fraga, S; Magro, F; Soares-da-Silva, P1
Chen, HI; Chuang, JI; Huang, AM; Jen, CJ; Kuo, YM; Liao, PC; Lin, LC; Liu, YF; Wu, FS; Yu, L1
Challet, E; Clesse, D; Cuesta, M; Mendoza, J; Pévet, P1
Bishop, C; Dupre, KB; Eskow, KL; Klioueva, A; Lormand, L; Negron, GE; Park, JY; Steiniger, A1
Fox, MA; French, HT; Huang, SJ; Jensen, CL; Murphy, DL; Stein, AR; Tolliver, TJ1
Haleem, DJ2
Haleem, DJ; Jabeen, B1
Haleem, DJ; Haleem, MA; Inam, QU; Jabeen, B1
Anselmo-Franci, JA; Bícego, KC; de Souza Moreno, V; Gargaglioni, LH; Szawka, RE1
Chevarin, C; Du, X; Hannan, AJ; Lanfumey, L; Leang, L; Pang, TY; Renoir, T; Zajac, MS1
Hu, P; Ma, L; Wang, C; Wang, YG; Ye, F; Zhao, X; Zhou, WH1
Bitar, MS; Masocha, W; Munawar, N1

Reviews

1 review(s) available for hydroxyindoleacetic acid and 8-hydroxy-2-(di-n-propylamino)tetralin

ArticleYear
Neurochemical mechanism of action of drugs which modify feeding via the serotoninergic system.
    Appetite, 1986, Volume: 7 Suppl

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Appetite; Appetite Depressants; Brain; Brain Chemistry; Dopamine; Endorphins; Feeding Behavior; Fenfluramine; gamma-Aminobutyric Acid; Hydroxyindoleacetic Acid; Neural Pathways; Norepinephrine; Piperazines; Pyridines; Quipazine; Rats; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes

1986

Other Studies

115 other study(ies) available for hydroxyindoleacetic acid and 8-hydroxy-2-(di-n-propylamino)tetralin

ArticleYear
Neurochemical effects of 5-HT1 receptor ligands in pigeons.
    European journal of pharmacology, 1992, Dec-15, Volume: 229, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding Sites; Brain; Columbidae; Hydroxyindoleacetic Acid; Indoles; Male; Methoxyhydroxyphenylglycol; Piperazines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

1992
Hippocampal 8-[3H]hydroxy-2-(di-n-propylamino) tetralin binding site densities, serotonin receptor (5-HT1A) messenger ribonucleic acid abundance, and serotonin levels parallel the activity of the hypothalamopituitary-adrenal axis in rat.
    Journal of neurochemistry, 1992, Volume: 59, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenalectomy; Animals; Binding Sites; Female; Hippocampus; Hydroxyindoleacetic Acid; Hypothalamo-Hypophyseal System; Pituitary-Adrenal System; Rats; Rats, Inbred F344; Rats, Inbred Lew; Rats, Inbred Strains; Receptors, Serotonin; RNA, Messenger; Serotonin; Tetrahydronaphthalenes

1992
The effects of rubidium, caesium and quinine on 5-HT-mediated behaviour in rat and mouse--1. Rubidium.
    Neuropharmacology, 1992, Volume: 31, Issue:5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Body Temperature; Brain; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; p-Chloroamphetamine; Potassium Channels; Rats; Rats, Inbred Strains; Rubidium; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes; Tranylcypromine

1992
Differences in the in vitro and in vivo 5-hydroxytryptamine extraction performance among three common microdialysis membranes.
    Journal of neurochemistry, 1992, Volume: 59, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cellulose; Dialysis; Hippocampus; Hydroxyindoleacetic Acid; Male; Membranes, Artificial; Osmolar Concentration; Polymers; Potassium; Rats; Rats, Sprague-Dawley; Serotonin

1992
Differential modulation of extracellular levels of 5-hydroxytryptamine in the rat frontal cortex by (R)- and (S)-zacopride.
    British journal of pharmacology, 1992, Volume: 107, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Buspirone; Diazepam; Dose-Response Relationship, Drug; Frontal Lobe; Hydroxyindoleacetic Acid; Male; Ondansetron; Rats; Serotonin; Serotonin Antagonists; Stereoisomerism

1992
Effects of cold stress on some 5-HT1A, 5-HT1C and 5-HT2 receptor-mediated responses.
    European journal of pharmacology, 1992, Aug-25, Volume: 219, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Blood Glucose; Body Temperature; Brain; Cold Temperature; Corticosterone; Hydroxyindoleacetic Acid; Male; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists

1992
Sex difference for tolerance of 5-HT1A receptor-mediated temperature and corticosterone responses in mice.
    European journal of pharmacology, 1992, Aug-25, Volume: 219, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Corticosterone; Female; Hydroxyindoleacetic Acid; Hypothalamus; Male; Mice; Receptors, Serotonin; Sex Characteristics

1992
Hippocampal 5-hydroxytryptamine synthesis is greater in female rats than in males and more decreased by the 5-HT1A agonist 8-OH-DPAT.
    Journal of neural transmission. General section, 1990, Volume: 79, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Female; Hippocampus; Hydroxyindoleacetic Acid; Male; Naphthalenes; Rats; Rats, Inbred Strains; Serotonin; Sex Characteristics; Tetrahydronaphthalenes

1990
A single dose of 8-OH-DPAT reduces raphe binding of [3H]8-OH-DPAT and increases the effect of raphe stimulation on 5-HT metabolism.
    European journal of pharmacology, 1990, Mar-20, Volume: 178, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Biogenic Amines; Cerebral Cortex; Electric Stimulation; Hippocampus; Hydroxyindoleacetic Acid; In Vitro Techniques; Kinetics; Male; Naphthalenes; Nerve Tissue Proteins; Raphe Nuclei; Rats; Serotonin; Tetrahydronaphthalenes; Tryptophan

1990
Different effects on the responses of functional pre- and postsynaptic 5-HT1A receptors by repeated treatment of rats with the 5-HT1A receptor agonist 8-OH-DPAT.
    Neuropharmacology, 1990, Volume: 29, Issue:2

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Body Temperature; Fenclonine; Hippocampus; Hydroxyindoleacetic Acid; Kinetics; Male; Medulla Oblongata; Naphthalenes; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Synapses; Tetrahydronaphthalenes

1990
The effects of Ca2+ antagonists and hydralazine on central 5-hydroxytryptamine biochemistry and function in rats and mice.
    British journal of pharmacology, 1990, Volume: 99, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Brain Chemistry; Calcium Channel Blockers; Felodipine; Hydralazine; Hydroxyindoleacetic Acid; Male; Methoxydimethyltryptamines; Mice; Mice, Inbred C57BL; Rats; Receptors, Serotonin; Serotonin; Species Specificity; Tetrahydronaphthalenes; Tranylcypromine; Tryptophan

1990
cis-(+)-8-OH-1-CH3-DPAT, (+)ALK-3, a novel stereoselective pharmacological probe for characterizing 5-HT release-controlling 5-HT1A autoreceptors. An in vivo brain microdialysis study.
    Naunyn-Schmiedeberg's archives of pharmacology, 1990, Volume: 341, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain Chemistry; Dialysis; Hippocampus; Hydroxyindoleacetic Acid; Male; Naphthalenes; Pindolol; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Stereoisomerism; Tetrahydronaphthalenes

1990
p-chlorophenylalanine attenuates the pituitary-adrenocortical response to 5-HT1A receptor agonists in mice.
    European journal of pharmacology, 1990, Jun-08, Volume: 181, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Corticosterone; Fenclonine; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred Strains; Piperazines; Pituitary Gland; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes

1990
Smoking-associated changes in the serotonergic systems of discrete regions of human brain.
    Psychopharmacology, 1990, Volume: 102, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aged; Aged, 80 and over; Binding, Competitive; Brain Chemistry; Female; Hippocampus; Humans; Hydroxyindoleacetic Acid; Ketanserin; Male; Middle Aged; Serotonin; Smoking; Tetrahydronaphthalenes

1990
Destruction of the nucleus raphe obscurus and potentiation of serotonin-mediated behaviors following administration of the neurotoxin 3-acetylpyridine.
    Brain research, 1990, Jun-18, Volume: 520, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature Regulation; Brain; Dose-Response Relationship, Drug; Hydroxyindoleacetic Acid; Male; Neurons; Neurotoxins; Pyridines; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spinal Cord; Stereotyped Behavior; Tetrahydronaphthalenes; Tremor

1990
Chronic 5-HT2 receptor antagonist treatment alters 5-HT1A autoregulatory control of 5-HT release in rat brain in vivo.
    Journal of neuroscience methods, 1990, Volume: 34, Issue:1-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain Chemistry; Cerebral Cortex; Chromatography, High Pressure Liquid; Hydroxyindoleacetic Acid; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Tetrahydronaphthalenes

1990
Alterations of central serotoninergic and dopaminergic neurotransmission in rats chronically treated with ipsapirone: biochemical and electrophysiological studies.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Autoradiography; Behavior, Animal; Binding Sites; Biogenic Amines; Body Weight; Brain; Brain Stem; Dihydroxyphenylalanine; Dopamine; Drug Administration Schedule; Electrophysiology; Hippocampus; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Membranes; Neurons; Pyrimidines; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Synaptic Transmission; Tetrahydronaphthalenes; Time Factors

1990
Serotonergic changes following proestrous treatment with p,p'-DDT.
    Neurotoxicology, 1990,Fall, Volume: 11, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; DDT; Female; Hydroxyindoleacetic Acid; Isomerism; Proestrus; Rats; Serotonin; Tetrahydronaphthalenes; Tritium

1990
Effects of idazoxan on dorsal raphe 5-hydroxytryptamine neuronal function.
    European journal of pharmacology, 1991, Jan-25, Volume: 193, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Anesthesia; Animals; Dioxanes; Electrophysiology; Hydroxyindoleacetic Acid; Idazoxan; In Vitro Techniques; Injections, Intraventricular; Iontophoresis; Male; Neurons; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Tetrahydronaphthalenes

1991
Extracellular serotonin levels change with behavioral state but not with pyrogen-induced hyperthermia.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1991, Volume: 11, Issue:9

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Body Temperature Regulation; Cats; Caudate Nucleus; Extracellular Space; Hydroxyindoleacetic Acid; Hyperthermia, Induced; Hypothalamus, Anterior; Neurons; Preoptic Area; Serotonin; Tetrahydronaphthalenes

1991
Recent advances in high-performance liquid chromatographic analysis of small molecules. Application of high-performance liquid chromatography with electrochemical detection to the study of neurotransmitters in vivo.
    Biochemical Society transactions, 1985, Volume: 13, Issue:6

    Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cerebral Cortex; Cerebral Ventricles; Chromatography, High Pressure Liquid; Corpus Striatum; Electric Stimulation; Epinephrine; Extracellular Space; Hydroxyindoleacetic Acid; Hypothalamus; Indoles; Medulla Oblongata; Phenylacetates; Rats; Serotonin; Tetrahydronaphthalenes

1985
Binding of the novel serotonin agonist 8-hydroxy-2-(di-n-propylamino) tetralin in normal and Alzheimer brain.
    Journal of neurochemistry, 1986, Volume: 46, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alzheimer Disease; Binding Sites; Brain; Cerebral Cortex; Frontal Lobe; Hydroxyindoleacetic Acid; Naphthalenes; Serotonin; Temporal Lobe; Tetrahydronaphthalenes

1986
Para-chlorophenylalanine prevents feeding induced by the serotonin agonist 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT).
    Psychopharmacology, 1986, Volume: 89, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Brain Chemistry; Eating; Fenclonine; Hydroxyindoleacetic Acid; Male; Naphthalenes; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Stereotyped Behavior; Tetrahydronaphthalenes

1986
Involvement of 5-HT1A- and alpha 2-receptors in the decreased 5-hydroxytryptamine release and metabolism in rat suprachiasmatic nucleus after intravenous 8-hydroxy-2-(n-dipropylamino) tetralin.
    British journal of pharmacology, 1986, Volume: 89, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Dioxanes; Hydroxyindoleacetic Acid; Idazoxan; Male; Methiothepin; Naphthalenes; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Serotonin; Serotonin; Suprachiasmatic Nucleus; Tetrahydronaphthalenes

1986
Neurochemical and behavioural evidence for mediation of the hyperphagic action of 8-OH-DPAT by 5-HT cell body autoreceptors.
    European journal of pharmacology, 1986, Oct-07, Volume: 129, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Eating; Feeding and Eating Disorders; Hydroxyindoleacetic Acid; Hyperphagia; Male; Naphthalenes; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes

1986
Inhibition of mouse killing behavior by serotonin-mimetic drugs: effects of partial alterations of serotonin neurotransmission.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 27, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Animals; Citalopram; Fenclonine; Fluoxetine; Hydroxyindoleacetic Acid; Male; Methoxydimethyltryptamines; Motor Activity; Propylamines; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Tetrahydronaphthalenes

1987
Single administration of 5-HT1A agonists decreases 5-HT1A presynaptic, but not postsynaptic receptor-mediated responses: relationship to antidepressant-like action.
    European journal of pharmacology, 1987, Jun-12, Volume: 138, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Behavior, Animal; Brain Chemistry; Cerebral Cortex; Eating; Hydroxyindoleacetic Acid; Male; Methoxydimethyltryptamines; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Synapses; Tetrahydronaphthalenes

1987
Serotonin and feeding responses of rats to amino acid imbalance: initial phase.
    The American journal of physiology, 1987, Volume: 253, Issue:5 Pt 2

    Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amino Acids; Animals; Anorexia; Dietary Proteins; Eating; Fenclonine; Hydroxyindoleacetic Acid; Isoleucine; Quipazine; Rats; Rats, Inbred Strains; Serotonin; Tetrahydronaphthalenes; Tryptophan

1987
Influence of route of administration on potency of the selective 5HT-1A agonist, 8-hydroxy-2-(di-n-propylamino)tetralin, in rats.
    Research communications in chemical pathology and pharmacology, 1987, Volume: 58, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain Chemistry; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Male; Naphthalenes; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes

1987
Feeding responses to a high dose of 8-OH-DPAT in young and adult rats: influence of food texture.
    European journal of pharmacology, 1988, Jul-07, Volume: 151, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animal Feed; Animals; Blood Glucose; Feeding Behavior; Hydroxyindoleacetic Acid; Hyperphagia; Male; Mesencephalon; Naphthalenes; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes

1988
5-HT1 agonists reduce 5-hydroxytryptamine release in rat hippocampus in vivo as determined by brain microdialysis.
    British journal of pharmacology, 1989, Volume: 96, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dialysis; Hippocampus; Hydroxyindoleacetic Acid; Indoles; Male; Naphthalenes; Pyrimidines; Rats; Rats, Inbred Strains; Serotonin; Tetrahydronaphthalenes

1989
Behavioural and biochemical consequences following activation of 5HT1-like and GABA receptors in the dorsal raphé nucleus of the rat.
    Neuropharmacology, 1988, Volume: 27, Issue:10

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Avoidance Learning; Body Temperature; Brain; Buspirone; Hydroxyindoleacetic Acid; Male; Muscimol; Posture; Pyrimidines; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Serotonin; Social Behavior; Tetrahydronaphthalenes; Tissue Distribution

1988
The 5-HT 1A receptor agonist, 8-OH-DPAT, preferentially activates cell body 5-HT autoreceptors in rat brain in vivo.
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 338, Issue:5

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Brain Chemistry; Dihydroxyphenylalanine; Dopamine; Hydroxyindoleacetic Acid; Male; Naphthalenes; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes

1988
In vivo measurement of extracellular 5-hydroxytryptamine in hippocampus of the anaesthetized rat using microdialysis: changes in relation to 5-hydroxytryptaminergic neuronal activity.
    Journal of neurochemistry, 1989, Volume: 53, Issue:1

    Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Dialysis; Electric Stimulation; Extracellular Space; Hippocampus; Hydroxyindoleacetic Acid; Injections; Male; Neurons; Perfusion; Raphe Nuclei; Rats; Serotonin; Tetrahydronaphthalenes; Tetrodotoxin

1989
Neurochemical changes in pigeon cerebrospinal fluid during chronic administration of buspirone or 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT).
    Pharmacology, biochemistry, and behavior, 1989, Volume: 32, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Columbidae; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Naphthalenes; Norepinephrine; Serotonin; Stereotaxic Techniques; Tetrahydronaphthalenes

1989
Hippocampal 5-HT synthesis and release in vivo is decreased by infusion of 8-OHDPAT into the nucleus raphe dorsalis.
    Neuroscience letters, 1989, May-22, Volume: 100, Issue:1-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Hippocampus; Hydroxyindoleacetic Acid; Male; Naphthalenes; Neural Pathways; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Tetrahydronaphthalenes

1989
A behavioural and biochemical study in mice and rats of putative selective agonists and antagonists for 5-HT1 and 5-HT2 receptors.
    British journal of pharmacology, 1985, Volume: 84, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Behavior, Animal; Body Temperature; Brain Chemistry; Histamine H2 Antagonists; Hydroxyindoleacetic Acid; Indoles; Kinetics; Male; Methoxydimethyltryptamines; Mice; Mice, Inbred C57BL; Motor Activity; Propranolol; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Species Specificity; Tetrahydronaphthalenes

1985
Biochemical evidence for the 5-HT agonist properties of PAT (8-hydroxy-2-(di-n-propylamino)tetralin) in the rat brain.
    European journal of pharmacology, 1984, May-04, Volume: 100, Issue:3-4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Brain; Brain Chemistry; Cerebral Cortex; Female; Hydroxyindoleacetic Acid; In Vitro Techniques; Membranes; Naphthalenes; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Serotonin; Spiperone; Synaptosomes; Tetrahydronaphthalenes; Tryptophan Hydroxylase

1984
A method for measuring monoamine turnover in animals using an irreversible inhibitor of aromatic L-amino acid decarboxylase, DL-alpha-mono fluoromethyldopa.
    Journal of pharmacological methods, 1984, Volume: 11, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Biogenic Amines; Brain Chemistry; Dopamine; Haloperidol; Hydroxyindoleacetic Acid; Male; Methyldopa; Mice; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Species Specificity; Tetrahydronaphthalenes; Time Factors

1984
Effects of chronic cocaine administration on the serotonergic system in the rat brain.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 46, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Antiparkinson Agents; Brain; Brain Chemistry; Cocaine; Ergolines; Hydroxyindoleacetic Acid; Ketanserin; Male; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin

1993
Derivatives of 2-(dipropylamino)tetralin: effect of the C8-substituent on the interaction with 5-HT1A receptors.
    Journal of medicinal chemistry, 1993, Dec-24, Volume: 36, Issue:26

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding, Competitive; Body Temperature; Brain; Cerebral Cortex; Chemical Phenomena; Chemistry, Physical; Dihydroxyphenylalanine; Dopamine; Hippocampus; Hydroxyindoleacetic Acid; Male; Molecular Structure; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reserpine; Serotonin; Stereoisomerism

1993
The profiles of interaction of yohimbine with anxiolytic and putative anxiolytic agents to modify 5-HT release in the frontal cortex of freely-moving rats.
    British journal of pharmacology, 1993, Volume: 110, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Clonidine; Dialysis; Diazepam; Drug Interactions; Extracellular Space; Frontal Lobe; Hydroxyindoleacetic Acid; Male; Ondansetron; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Yohimbine

1993
Effects of chronic mianserin administration on serotonin metabolism and receptors in the 5-hydroxytryptophan depression model.
    Progress in neuro-psychopharmacology & biological psychiatry, 1994, Volume: 18, Issue:1

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain Chemistry; Cerebral Cortex; Depression; Hydroxyindoleacetic Acid; Kinetics; Male; Membranes; Mianserin; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin

1994
Gonadotropin and prolactin secretion in prepubertal female rats treated with 8-hydroxy-2-(di-n-propylamino) tetralin.
    Journal of neural transmission. General section, 1993, Volume: 94, Issue:3

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Female; Follicle Stimulating Hormone; Gonadotropins; Hydroxyindoleacetic Acid; Hypothalamus; Luteinizing Hormone; Pituitary Gland; Prolactin; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Sexual Maturation

1993
Changes in serotonin level in the hypoglossal nucleus region during carbachol-induced atonia.
    Brain research, 1994, May-09, Volume: 645, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain Stem; Carbachol; Cats; Decerebrate State; Hydroxyindoleacetic Acid; Hypoglossal Nerve; Microdialysis; Muscle Tonus; Muscular Diseases; Pons; Serotonin; Sleep, REM

1994
Effects of the serotonin1A agonist, 8-hydroxy-2-(di-n-propylamino)tetralin on neurochemical responses to stress.
    Journal of neurochemistry, 1995, Volume: 64, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Corticosterone; Dopamine; Hydroxyindoleacetic Acid; Male; Norepinephrine; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Receptor Agonists; Stress, Psychological

1995
The effect of tianeptine and sertraline in three animal models of depression.
    Neuropharmacology, 1994, Volume: 33, Issue:8

    Topics: 1-Naphthylamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Body Temperature; Corticosterone; Depressive Disorder; Hydroxyindoleacetic Acid; Hypothalamus; Indoles; Male; Motor Activity; Neurotransmitter Agents; Olfactory Bulb; Rats; Rats, Sprague-Dawley; Sertraline; Thiazepines

1994
Age-related behavioural, neurochemical and radioligand binding changes in the central 5-HT system of Sprague-Dawley rats.
    Psychopharmacology, 1993, Volume: 113, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Amphetamines; Animals; Behavior, Animal; Binding, Competitive; Brain Chemistry; Dose-Response Relationship, Drug; Guanosine Triphosphate; Hydroxyindoleacetic Acid; Ketanserin; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Receptor Agonists

1993
Depletion of brain serotonin by 5,7-DHT: effects on the 8-OH-DPAT-induced changes of sleep and waking in the rat.
    Psychopharmacology, 1994, Volume: 115, Issue:1-2

    Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Biogenic Monoamines; Brain Chemistry; Dose-Response Relationship, Drug; Hydroxyindoleacetic Acid; Male; Rats; Rats, Wistar; Receptors, Presynaptic; Receptors, Serotonin; Serotonin; Sleep; Sleep, REM; Wakefulness

1994
Effects of two stressors on behaviour in the elevated X-maze: preliminary investigation of their interaction with 8-OH-DPAT.
    Psychopharmacology, 1994, Volume: 116, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anxiety; Behavior, Animal; Body Weight; Brain Chemistry; Corticosterone; Exploratory Behavior; Hydroxyindoleacetic Acid; Male; Rats; Rats, Wistar; Restraint, Physical; Serotonin; Stress, Psychological; Water Deprivation

1994
Gender and estrous cycle effects of the 5-HT1A agonist, 8-OH-DPAT, on hypothalamic serotonin.
    Pharmacology, biochemistry, and behavior, 1995, Volume: 51, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Chromatography, High Pressure Liquid; Estradiol; Estrus; Female; Hydroxyindoleacetic Acid; Hypothalamus; Male; Ovariectomy; Rats; Rats, Inbred F344; Serotonin; Serotonin Receptor Agonists; Sex Characteristics

1995
The presence of a serotonin uptake inhibitor alters pharmacological manipulations of serotonin release.
    Neuroscience, 1993, Volume: 52, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Chromatography, High Pressure Liquid; Citalopram; Corpus Striatum; Dialysis; Electrochemistry; Fenfluramine; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Sodium Channels; Tetrodotoxin

1993
In vivo brain dialysis study of the somatodendritic release of serotonin in the Raphe nuclei of the rat: effects of 8-hydroxy-2-(di-n-propylamino)tetralin.
    Journal of neurochemistry, 1993, Volume: 60, Issue:5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dendrites; Dialysis; Hippocampus; Hydroxyindoleacetic Acid; Male; p-Chloroamphetamine; Potassium; Raphe Nuclei; Rats; Rats, Wistar; Serotonin

1993
Acute uptake inhibition increases extracellular serotonin in the rat forebrain.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:3

    Topics: 1-Naphthylamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Corpus Striatum; Diencephalon; Fenfluramine; Fluoxetine; Hydroxyindoleacetic Acid; Male; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Sertraline

1993
(-)Tertatolol is a potent antagonist at pre- and postsynaptic serotonin 5-HT1A receptors in the rat brain.
    Naunyn-Schmiedeberg's archives of pharmacology, 1993, Volume: 347, Issue:5

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Brain; Electrophysiology; Hydroxyindoleacetic Acid; Isomerism; Male; Neurons; Propanolamines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Thiophenes

1993
Synthesis of (+)-(R)- and (-)-(S)-5-hydroxy-2-methyl-2-dipropylaminotetralin: effects on rat hippocampal output of 5-HT, 5-HIAA, and DOPAC as determined by in vivo microdialysis.
    Chirality, 1993, Volume: 5, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Crystallization; Dialysis; Hippocampus; Hydroxyindoleacetic Acid; Magnetic Resonance Spectroscopy; Male; Molecular Conformation; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Serotonin; Stereoisomerism; X-Ray Diffraction

1993
Stress-induced changes of extracellular 5-hydroxyindoleacetic acid concentrations followed in the nucleus raphe dorsalis and the frontal cortex of the rat.
    Brain research, 1993, Jun-18, Volume: 614, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Cold Temperature; Extracellular Space; Handling, Psychological; Hydroxyindoleacetic Acid; Immobilization; Male; Physical Exertion; Prefrontal Cortex; Raphe Nuclei; Rats; Stress, Psychological; Telemetry

1993
Modulation of 5HT1A receptors in the hippocampus and the raphe area of rats treated with clonazepam.
    Progress in neuro-psychopharmacology & biological psychiatry, 1993, Volume: 17, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Clonazepam; Hippocampus; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Membranes; Methoxydimethyltryptamines; Radioligand Assay; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin

1993
Are 5-HT1A autoreceptors involved in the inhibitory effect of ipsapirone on cold-elicited thyrotropin secretion?
    Neuroendocrinology, 1993, Volume: 57, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Glucose; Cold Temperature; Corticosterone; Fenclonine; Hydroxyindoleacetic Acid; Hypothalamus; Male; Metergoline; Pindolol; Proadifen; Pyrimidines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Thyrotropin

1993
Behavioural and neurochemical evidence for the decrease of brain extracellular 5-HT by the antidepressant drug tianeptine.
    Neuropharmacology, 1993, Volume: 32, Issue:9

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Brain Chemistry; Dialysis; Extracellular Space; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Serotonin; Thiazepines

1993
Central administration of 8-OH-DPAT and mCPP stimulates prolactin secretion in ovariectomized, estrogen-treated rats: lack of an effect on tuberoinfundibular dopaminergic neuron activity.
    Life sciences, 1996, Volume: 58, Issue:14

    Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Arcuate Nucleus of Hypothalamus; Dopamine; Estradiol; Estradiol Congeners; Female; Hydroxyindoleacetic Acid; Injections, Intraventricular; Neurons; Ovariectomy; Piperazines; Prolactin; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Receptor Agonists; Stimulation, Chemical

1996
4-(2'-Methoxyphenyl)-1-[2'-[N-(2"-pyridinyl)-p-iodobenzamido]ethyl] piperazine and 4-(2'-methoxyphenyl)-1-[2'-[N-(2"-pyridinyl)-p- fluorobenzamido]ethyl]piperazine, two new antagonists at pre- and postsynaptic serotonin-1A receptors.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Autoreceptors; Body Temperature; Brain Chemistry; Dose-Response Relationship, Drug; Guanylyl Imidodiphosphate; Hydroxyindoleacetic Acid; Male; Piperazines; Posture; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists

1996
Potential anxiolytic properties of R-(+)-8-OSO2CF3-PAT, a 5-HT 1A receptor agonist.
    European journal of pharmacology, 1996, Feb-22, Volume: 297, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Behavior, Animal; Brain; Hydroxyindoleacetic Acid; Male; Rats; Rats, Wistar; Serotonin; Serotonin Receptor Agonists

1996
Alterations in serotonin parameters in brain of thiamine-deficient rats are evident prior to the appearance of neurological symptoms.
    Journal of neurochemistry, 1996, Volume: 67, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amines; Animals; Autoradiography; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Feeding Behavior; Hydroxyindoleacetic Acid; Hypothermia; Ketanserin; Male; Monoamine Oxidase; Nervous System Diseases; Neurologic Examination; Pyrithiamine; Rats; Rats, Sprague-Dawley; Serotonin; Thiamine Deficiency; Tritium

1996
The effects of clozapine and haloperidol on serotonin-1A, -2A and -2C receptor gene expression and serotonin metabolism in the rat forebrain.
    Neuroscience, 1996, Volume: 73, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Cerebral Cortex; Clozapine; Corpus Striatum; Haloperidol; Hippocampus; Hydroxyindoleacetic Acid; In Situ Hybridization; Ketanserin; Male; Organ Specificity; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reference Values; RNA, Messenger; Serotonin; Transcription, Genetic; Tritium

1996
Downregulation of muscarinic- and 5-HT1B-mediated modulation of [3H]acetylcholine release in hippocampal slices of rats with fimbria-fornix lesions and intrahippocampal grafts of septal origin.
    Brain research, 1995, Dec-18, Volume: 704, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Atropine; Brain Tissue Transplantation; Choline; Choline O-Acetyltransferase; Cholinergic Fibers; Cholinesterase Inhibitors; Diffusion Chambers, Culture; Down-Regulation; Electric Stimulation; Female; Hippocampus; Hydroxyindoleacetic Acid; Mecamylamine; Methiothepin; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Nicotinic Antagonists; Norepinephrine; Oxotremorine; Physostigmine; Pyridines; Pyrroles; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Receptors, Serotonin; Septal Nuclei; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tritium

1995
The 5-HT1A receptor antagonist (S)-UH-301 decreases dopamine release in the rat nucleus accumbens and striatum.
    Journal of neural transmission (Vienna, Austria : 1996), 1996, Volume: 103, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Injections, Subcutaneous; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Wistar; Serotonin Antagonists; Serotonin Receptor Agonists

1996
Effects of systemic phenylpropanolamine and fenfluramine on serotonin activity within rat paraventricular hypothalamus.
    Physiology & behavior, 1996, Volume: 59, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Appetite Depressants; Eating; Extracellular Space; Fenfluramine; Hydroxyindoleacetic Acid; Microdialysis; Paraventricular Hypothalamic Nucleus; Phenylpropanolamine; Rats; Rats, Sprague-Dawley; Receptors, Presynaptic; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists

1996
Combined administration of a 5-hydroxytryptamine (5-HT)1D antagonist and a 5-HT reuptake inhibitor synergistically increases 5-HT release in guinea pig hypothalamus in vivo.
    Journal of neurochemistry, 1996, Volume: 67, Issue:5

    Topics: 1-Naphthylamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Drug Synergism; Guinea Pigs; Hydroxyindoleacetic Acid; Hypothalamus; Indoles; Kinetics; Neurons; Oxadiazoles; Piperazines; Pyridines; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Sertraline

1996
Effects of a chronic lithium treatment on cortical serotonin uptake sites and 5-HT1A receptors.
    Neurochemical research, 1997, Volume: 22, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cell Membrane; Cerebral Cortex; Citalopram; Humans; Hydroxyindoleacetic Acid; Lithium; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Tritium

1997
Central serotonergic systems in the spontaneously hypertensive and Lewis rat strains that differ in the elevated plus-maze test of anxiety.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 281, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anxiety; Behavior, Animal; Citalopram; Female; Hippocampus; Hydroxyindoleacetic Acid; Ketanserin; Male; Mesencephalon; Rats; Rats, Inbred Lew; Rats, Inbred SHR; Receptors, Serotonin; Serotonin; Tritium; Tryptophan Hydroxylase

1997
Actions of nimodipine on the serotonergic systems of rat brain.
    General pharmacology, 1997, Volume: 29, Issue:3

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Brain Chemistry; Calcium Channel Blockers; Hydroxyindoleacetic Acid; Male; Nimodipine; Rats; Rats, Sprague-Dawley; Receptors, Presynaptic; Serotonin; Serotonin Receptor Agonists; Synaptic Transmission; Vasodilator Agents

1997
Dissociation of hippocampal serotonin release and locomotor activity following pharmacological manipulations of the median raphe nucleus.
    Behavioural brain research, 1997, Volume: 89, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Baclofen; Extracellular Space; GABA Agonists; Hippocampus; Hydroxyindoleacetic Acid; Male; Microdialysis; Motor Activity; Muscimol; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Receptor Agonists

1997
Dietary fat type influences protein consumption in rats given 8-hydroxy-2-(Di-n-propylamino)tetralin.
    Physiology & behavior, 1998, Volume: 63, Issue:5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Corn Oil; Dietary Fats; Dietary Proteins; Fats; Fenfluramine; Food Preferences; Hydroxyindoleacetic Acid; Male; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Receptor Agonists

1998
Influence of serotoninergic drugs on in vivo dopamine extracellular output in rat striatum.
    Journal of neuroscience research, 1998, Jun-01, Volume: 52, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Clomipramine; Corpus Striatum; Dopamine; Extracellular Space; Hydroxyindoleacetic Acid; Male; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists

1998
MDMA ('Ecstasy') enhances 5-HT1A receptor density and 8-OH-DPAT-induced hypothermia: blockade by drugs preventing 5-hydroxytryptamine depletion.
    European journal of pharmacology, 1998, Apr-10, Volume: 346, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Hydroxyindoleacetic Acid; Hypothalamus; Hypothermia; Male; N-Methyl-3,4-methylenedioxyamphetamine; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Agents; Serotonin Receptor Agonists

1998
Reversal of fenfluramine and fluoxetine anorexia by 8-OH-DPAT is attenuated following raphe injection of 5,7-dihydroxytryptamine.
    Brain research, 1998, Jul-27, Volume: 800, Issue:1

    Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anorexia; Brain; Corpus Striatum; Dopamine; Feeding Behavior; Fenfluramine; Fluoxetine; Hippocampus; Hydroxyindoleacetic Acid; Hypothalamus; Infusions, Parenteral; Male; Neurotoxins; Norepinephrine; Piperazines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Receptor Agonists

1998
5-HT1A receptor agonist (8-OH-DPAT) and 5-HT2 receptor agonist (DOI) disrupt the non-cognitive performance of rats in a working memory task.
    Journal of psychopharmacology (Oxford, England), 1998, Volume: 12, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Brain; Conditioning, Operant; Dose-Response Relationship, Drug; Hydroxyindoleacetic Acid; Male; Mental Recall; Norepinephrine; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists

1998
Potentiating action of MKC-242, a selective 5-HT1A receptor agonist, on the photic entrainment of the circadian activity rhythm in hamsters.
    British journal of pharmacology, 1998, Volume: 125, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Circadian Rhythm; Cricetinae; Dioxanes; Dioxoles; Geniculate Ganglion; Hydroxyindoleacetic Acid; Light; Male; Mesocricetus; Motor Activity; Photic Stimulation; Proto-Oncogene Proteins c-fos; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists; Suprachiasmatic Nucleus

1998
Activity and onset of action of reboxetine and effect of combination with sertraline in an animal model of depression.
    European journal of pharmacology, 1999, Jan-08, Volume: 364, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amygdala; Analgesics; Animals; Antidepressive Agents; Body Temperature; Clonidine; Depression; Disease Models, Animal; Drug Therapy, Combination; Exploratory Behavior; Hydroxyindoleacetic Acid; Male; Morpholines; Motor Activity; Olfactory Bulb; Rats; Rats, Sprague-Dawley; Reboxetine; Serotonin Receptor Agonists; Sertraline; Swimming

1999
Anxiety and increased 5-HT1A receptor response in NCAM null mutant mice.
    Journal of neurobiology, 1999, Sep-05, Volume: 40, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Anxiety; Autoradiography; Binding, Competitive; Brain Chemistry; Buspirone; Diazepam; Exploratory Behavior; Genotype; Hydroxyindoleacetic Acid; Male; Maze Learning; Mice; Mice, Knockout; Mice, Mutant Strains; Mice, Transgenic; Neural Cell Adhesion Molecules; Potassium Channels; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Spatial Behavior

1999
Dependence of serotonin release in the locus coeruleus on dorsal raphe neuronal activity.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 359, Issue:5

    Topics: 5,6-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Pressure; Electric Stimulation; Hot Temperature; Hydroxyindoleacetic Acid; Locus Coeruleus; Male; Microinjections; Neurons; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists; Stimulation, Chemical; Time Factors

1999
A nitric oxide synthase inhibitor reduces hyperphagia induced in rats by the 5-HT(1A) receptor agonist, 8-OH-DPAT, independently of hypothalamic serotonin metabolism.
    European journal of pharmacology, 2000, Aug-25, Volume: 402, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Enzyme Inhibitors; Hydroxyindoleacetic Acid; Hyperphagia; Hypothalamus; Male; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists

2000
Brain serotonin dysfunction accounts for aggression in male mice lacking neuronal nitric oxide synthase.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Jan-30, Volume: 98, Issue:3

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Animals; Brain; Fenclonine; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Posture; Pyridines; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Regression Analysis; Serotonin; Serotonin Receptor Agonists

2001
Beta-amyloid(1-42)-induced cholinergic lesions in rat nucleus basalis bidirectionally modulate serotonergic innervation of the basal forebrain and cerebral cortex.
    Neurobiology of disease, 2001, Volume: 8, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amyloid beta-Peptides; Animals; Anxiety; Basal Nucleus of Meynert; Cholinergic Fibers; Densitometry; Hydroxyindoleacetic Acid; Male; Maze Learning; Nerve Regeneration; Neural Pathways; Peptide Fragments; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists; Somatosensory Cortex; Tritium

2001
Role of 5-HT1A receptors in the mediation of acute citalopram effects: a 8-OH-DPAT challenge study.
    Progress in neuro-psychopharmacology & biological psychiatry, 2002, Volume: 26, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anxiety; Brain; Citalopram; Drug Synergism; Exploratory Behavior; Female; Hydroxyindoleacetic Acid; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists

2002
Effect of 8-OH-DPAT on temporal discrimination following central 5-hydroxytryptamine depletion.
    Pharmacology, biochemistry, and behavior, 2002, Volume: 71, Issue:4

    Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain Chemistry; Conditioning, Operant; Discrimination, Psychological; Dopamine; Female; Hydroxyindoleacetic Acid; Norepinephrine; Rats; Rats, Wistar; Receptors, Presynaptic; Serotonin; Serotonin Agents; Serotonin Receptor Agonists; Synapses; Time Perception

2002
Postsynaptic 5-HT(1A) receptors mediate an increase in locomotor activity in the monoamine-depleted rat.
    Psychopharmacology, 2002, Volume: 163, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Uptake Inhibitors; Animals; Biogenic Monoamines; Brain Chemistry; Buspirone; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Hydroxyindoleacetic Acid; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Presynaptic; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reserpine; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synapses

2002
Increases in the release and metabolism of serotonin in nucleus parafascicularis thalami following systemically administered morphine in the rat.
    Neuroscience letters, 2002, Nov-08, Volume: 332, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesics, Opioid; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Electrochemistry; Extracellular Space; Hydroxyindoleacetic Acid; Intralaminar Thalamic Nuclei; Male; Microdialysis; Morphine; Rats; Rats, Long-Evans; Serotonin; Vocalization, Animal

2002
8-OHDPAT-induced disruption of prepulse inhibition in rats is attenuated by prolonged corticosterone treatment.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:7

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenal Glands; Animals; Anti-Inflammatory Agents; Autoradiography; Binding Sites; Body Weight; Corticosterone; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation; Hippocampus; Hydroxyindoleacetic Acid; In Situ Hybridization; Male; Neural Inhibition; Organ Size; Piperazines; Raphe Nuclei; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reflex, Startle; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors

2003
Serotonin, serotonin 5-HT(1A) receptors and dopamine in blood peripheral lymphocytes of major depression patients.
    International immunopharmacology, 2003, Volume: 3, Issue:9

    Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adolescent; Adult; Chromatography, High Pressure Liquid; Depressive Disorder; Dopamine; Female; Humans; Hydroxyindoleacetic Acid; Lymphocytes; Male; Middle Aged; Psychoneuroimmunology; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin Receptor Agonists

2003
Involvement of the brain serotonergic system in the locomotor stimulant effects of chlorpheniramine in Wistar rats: implication of postsynaptic 5-HT1A receptors.
    Behavioural brain research, 2004, Jan-05, Volume: 148, Issue:1-2

    Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Body Temperature; Brain; Brain Chemistry; Chlorpheniramine; Chromatography, High Pressure Liquid; Dopamine; Histamine H1 Antagonists; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Motor Activity; Norepinephrine; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists; Species Specificity; Statistics, Nonparametric; Time Factors

2004
Effects of nociceptin on the exploratory behavior of mice in the hole-board test.
    European journal of pharmacology, 2004, Apr-05, Volume: 489, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amygdala; Analgesics, Opioid; Animals; Emotions; Exploratory Behavior; Hippocampus; Hydroxyindoleacetic Acid; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Nociceptin; Opioid Peptides; Piperazines; Pyridines; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

2004
Nucleus accumbens serotonin1A receptors control cocaine-induced hyperactivity but not local serotonin increase: an in vivo microdialysis study.
    Neuropharmacology, 2004, Volume: 47, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Cocaine; Hydroxyindoleacetic Acid; Hyperkinesis; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin Receptor Agonists

2004
Changes of body temperature and extracellular serotonin level in the preoptic area and anterior hypothalamus after thermal or serotonergic pharmacological stimulation of freely moving rats.
    Life sciences, 2004, Oct-15, Volume: 75, Issue:22

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anterior Hypothalamic Nucleus; Body Temperature; Cold Temperature; Fluoxetine; Hot Temperature; Hydroxyindoleacetic Acid; Male; Microdialysis; Preoptic Area; Rats; Rats, Wistar; Serotonin

2004
Fatigue of cholestasis and the serotoninergic neurotransmitter system in the rat.
    Hepatology (Baltimore, Md.), 2005, Volume: 41, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Brain; Cholestasis; Dose-Response Relationship, Drug; Fatigue; Hydroxyindoleacetic Acid; Hyperkinesis; Male; Microdialysis; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists; Swimming; Syndrome

2005
Anxiolytic-like effect of a serotonergic ligand with high affinity for 5-HT1A, 5-HT2A and 5-HT3 receptors.
    European journal of pharmacology, 2005, Mar-21, Volume: 511, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Anti-Anxiety Agents; Behavior, Animal; Binding, Competitive; Body Temperature Regulation; Bradycardia; Colforsin; Dopamine; Dose-Response Relationship, Drug; Guinea Pigs; HeLa Cells; Humans; Hydroxyindoleacetic Acid; Hypothalamus; Ileum; In Vitro Techniques; Male; Membrane Potentials; Mice; Motor Activity; Muscle Contraction; Neurons; Piperazines; Pyrazines; Radioligand Assay; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Receptor Agonists; Social Behavior; Transfection

2005
Alteration of 5-HIAA levels in frontal cortex and dorsal raphe nucleus in rats treated with combined administration of tryptophan and ethanol.
    The Journal of toxicological sciences, 2006, Volume: 31, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Ethanol; Frontal Lobe; Hydroxyindoleacetic Acid; Male; Piperazines; Pyridines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Serotonin; Tryptophan

2006
5-HT-1A receptor responsiveness following subchronic administration of buspirone.
    Pakistan journal of pharmaceutical sciences, 2006, Volume: 19, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Buspirone; Hippocampus; Hydroxyindoleacetic Acid; Male; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Serotonin

2006
Role of serotonin-1A receptors in restraint-induced behavioral deficits and adaptation to repeated restraint stress in rats.
    The International journal of neuroscience, 2007, Volume: 117, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adaptation, Physiological; Analysis of Variance; Animals; Behavior, Animal; Behavioral Symptoms; Dose-Response Relationship, Drug; Eating; Hydroxyindoleacetic Acid; Male; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Restraint, Physical; Serotonin; Serotonin Receptor Agonists; Stress, Psychological

2007
Reversal of haloperidol-induced tardive vacuous chewing movements and supersensitive somatodendritic serotonergic response by buspirone in rats.
    Pharmacology, biochemistry, and behavior, 2007, Volume: 87, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Buspirone; Chromatography, High Pressure Liquid; Dendrites; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Electrochemistry; Exploratory Behavior; Haloperidol; Hydroxyindoleacetic Acid; Male; Motor Activity; Rats; Rats, Wistar; Serotonin; Serotonin Receptor Agonists; Serotonin Syndrome; Stereotyped Behavior

2007
Short-term effect on intestinal epithelial Na(+)/H(+) exchanger by Gi(alpha1,2)-coupled 5-HT(1A) and G(q/11)-coupled 5-HT(2) receptors.
    Life sciences, 2007, Jul-26, Volume: 81, Issue:7

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Blotting, Western; Cells, Cultured; Epithelium; Humans; Hydrogen-Ion Concentration; Hydroxyindoleacetic Acid; Immunoglobulin G; Intestinal Mucosa; Receptor, Serotonin, 5-HT1A; Receptors, G-Protein-Coupled; Receptors, Serotonin, 5-HT2; Serotonin; Serotonin Receptor Agonists; Signal Transduction; Sodium-Hydrogen Exchangers

2007
Treadmill exercise enhances passive avoidance learning in rats: the role of down-regulated serotonin system in the limbic system.
    Neurobiology of learning and memory, 2008, Volume: 89, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amygdala; Animals; Avoidance Learning; Down-Regulation; Exercise Test; Fear; Hydroxyindoleacetic Acid; Limbic System; Male; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists

2008
Serotonergic activation potentiates light resetting of the main circadian clock and alters clock gene expression in a diurnal rodent.
    Experimental neurology, 2008, Volume: 210, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Behavior, Animal; Cell Cycle Proteins; Circadian Rhythm; Dose-Response Relationship, Drug; Female; Fluoxetine; Gene Expression Regulation; Hydroxyindoleacetic Acid; Light; Male; Period Circadian Proteins; Rats; Receptors, Cytoplasmic and Nuclear; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Suprachiasmatic Nucleus

2008
Effects of coincident 5-HT1A receptor stimulation and NMDA receptor antagonism on L-DOPA-induced dyskinesia and rotational behaviors in the hemi-parkinsonian rat.
    Psychopharmacology, 2008, Volume: 199, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Levodopa; Male; Medial Forebrain Bundle; Motor Activity; Motor Skills; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptors, N-Methyl-D-Aspartate; Serotonin; Serotonin Receptor Agonists; Stereotyped Behavior

2008
Neurochemical, behavioral, and physiological effects of pharmacologically enhanced serotonin levels in serotonin transporter (SERT)-deficient mice.
    Psychopharmacology, 2008, Volume: 201, Issue:2

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Brain Chemistry; Catecholamines; Clorgyline; Dopamine Uptake Inhibitors; Drug Synergism; Drug Therapy, Combination; Female; Hydroxyindoleacetic Acid; Hypothermia; Male; Mice; Mice, Knockout; Monoamine Oxidase Inhibitors; Phenols; Piperazines; Pyridines; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Serotonin Syndrome; Sulfonamides; Tranylcypromine

2008
Exaggerated feedback control decreases brain serotonin concentration and elicits hyperactivity in a rat model of diet-restriction-induced anorexia nervosa.
    Appetite, 2009, Volume: 52, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anorexia Nervosa; Brain Chemistry; Feedback, Physiological; Female; Food Deprivation; Hydroxyindoleacetic Acid; Hypothalamus; Psychomotor Agitation; Rats; Rats, Wistar; Serotonin; Serotonin Receptor Agonists

2009
Desensitization of pre and post synaptic 5-HT-1A receptor responses following long term consumption of sugar rich diet: implications for sugar-induced obesity.
    Pakistan journal of pharmaceutical sciences, 2008, Volume: 21, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Body Weight; Brain; Dietary Sucrose; Disease Models, Animal; Eating; Hydroxyindoleacetic Acid; Hyperkinesis; Hyperphagia; Male; Obesity; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Presynaptic; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists; Serotonin Syndrome; Time Factors

2008
Long-term consumption of sugar-rich diet decreases the effectiveness of somatodendritic serotonin-1A receptors.
    Nutritional neuroscience, 2008, Volume: 11, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dietary Sucrose; Eating; Feedback, Physiological; Hydroxyindoleacetic Acid; Hyperphagia; Hypothalamus; Male; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists; Tryptophan

2008
Serotonergic mechanisms on breathing modulation in the rat locus coeruleus.
    Pflugers Archiv : European journal of physiology, 2010, Volume: 459, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Amphetamines; Animals; Hydroxyindoleacetic Acid; Hypercapnia; Idazoxan; Ketanserin; Locus Coeruleus; Male; Microinjections; Piperazines; Pulmonary Ventilation; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Respiration; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists

2010
Sexually dimorphic serotonergic dysfunction in a mouse model of Huntington's disease and depression.
    PloS one, 2011, Volume: 6, Issue:7

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Depression; Disease Models, Animal; Feeding Behavior; Female; Gene Expression Regulation; Huntington Disease; Hydroxyindoleacetic Acid; Hyperthermia, Induced; Male; Mice; Mutation; Raphe Nuclei; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Serotonin; Sertraline; Sex Characteristics; Swimming

2011
Behavioral deficits and exaggerated feedback control over raphe-hippocampal serotonin neurotransmission in restrained rats.
    Pharmacological reports : PR, 2011, Volume: 63, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anxiety; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Feedback, Physiological; Hippocampus; Hydroxyindoleacetic Acid; Male; Prefrontal Cortex; Raphe Nuclei; Rats; Rats, Wistar; Restraint, Physical; Serotonin

2011
Report: Protective effects of rice bran oil in haloperidol-induced tardive dyskinesia and serotonergic responses in rats.
    Pakistan journal of pharmaceutical sciences, 2016, Volume: 29, Issue:4 Suppl

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Dyskinesias; Haloperidol; Hydroxyindoleacetic Acid; Male; Neostriatum; Neuroprotective Agents; Plant Oils; Postural Balance; Psychomotor Performance; Rats; Rats, Wistar; Rice Bran Oil; Serotonin; Tardive Dyskinesia

2016
Genistein, a dietary soy isoflavone, exerts antidepressant-like effects in mice: Involvement of serotonergic system.
    Neurochemistry international, 2017, Volume: 108

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Depression; Dose-Response Relationship, Drug; Genistein; Hydroxyindoleacetic Acid; Isoflavones; Male; Mice; Mice, Inbred ICR; Piperazines; Pyridines; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

2017
Activation of 5-HT1A Receptors Normalizes the Overexpression of Presynaptic 5-HT1A Receptors and Alleviates Diabetic Neuropathic Pain.
    International journal of molecular sciences, 2023, Sep-20, Volume: 24, Issue:18

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Hydroxyindoleacetic Acid; Hyperalgesia; Neuralgia; Rats; Serotonin; Tryptophan; Tryptophan Oxygenase

2023