hydroxyhexamide has been researched along with acetohexamide in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (61.54) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dubuc, JC; Raymond, Y | 1 |
| Sakamoto, T; Sato, K; Takagishi, Y; Tomita, K | 1 |
| Shibutani, Y; Yokota, T | 1 |
| Abe, H; Imamura, Y; Kojima, Y; Otagiri, M | 1 |
| Akita, H; Higuchi, T; Imamura, Y; Kojima, Y; Oishi, T; Otagiri, M | 1 |
| Asada, S; Nagamine, S; Nakae, H | 2 |
| Imamura, Y; Kojima, Y; Otagiri, M | 1 |
| Ichibagase, H; Imamura, Y; Kojima, Y | 1 |
| Akita, H; Hirayama, K; Imamura, Y; Kawana, T; Kurashima, K; Nozawa, M; Seri, K | 1 |
| Akita, H; Imamura, Y; Kurashima, K; Sanai, K; Seri, K | 1 |
| Akita, H; Imamura, Y; Sanai, K; Seri, K | 1 |
| Akita, H; Imamura, Y; Kaneko, M; Otagiri, M; Shimada, H; Takada, H | 1 |
13 other study(ies) available for hydroxyhexamide and acetohexamide
| Article | Year |
|---|---|
[A study of certain factors which might modify the pharmacological action of hydroxyhexamide, an active metabolite of the oral hypoglycemic agent: acetohexamide (author's transl)].
Topics: Acetohexamide; Animals; Binding, Competitive; Dogs; Hydrogen-Ion Concentration; Protein Binding; Salicylates | 1978 |
[High-performance liquid chromatographic determination of acetohexamide and its metabolite, hydroxyhexamide (author's transl)].
Topics: Acetohexamide; Animals; Chromatography, High Pressure Liquid; Dogs; Humans | 1979 |
A case of acetohexamide-induced hypoglycemia: the influence of hypothyroidism on the metabolism of acetohexamide.
Topics: Acetohexamide; Aged; Diabetes Mellitus, Type 2; Half-Life; Humans; Hypoglycemia; Hypothyroidism; Male; Thyroxine | 1991 |
In vivo and in vitro binding of (-)-hydroxyhexamide, a major metabolite of acetohexamide, to rabbit serum.
Topics: Acetohexamide; Animals; Binding, Competitive; Blood Proteins; In Vitro Techniques; Male; Protein Binding; Rabbits | 1989 |
Stereoselective reduction of acetohexamide in cytosol of rabbit liver.
Topics: Acetohexamide; Alcohol Oxidoreductases; Animals; Chromatography, Ion Exchange; Cytosol; Liver; Magnetic Resonance Spectroscopy; Male; Oxidation-Reduction; Rabbits; Stereoisomerism | 1989 |
Comparative pharmacokinetics of acetohexamide and its metabolite, hydroxyhexamide in laboratory animals.
Topics: Acetohexamide; Animals; Guinea Pigs; Injections, Intraperitoneal; Injections, Intravenous; Male; Rabbits; Rats; Rats, Inbred Strains | 1989 |
Metabolic reduction of acetohexamide in rat kidney: sex difference and effect of streptozotocin-induced diabetes.
Topics: Acetohexamide; Animals; Diabetes Mellitus, Experimental; Female; Kidney; Male; Oxidation-Reduction; Rats; Rats, Inbred Strains; Sex Factors; Streptozocin; Subcellular Fractions | 1988 |
[Interconversion model analysis for acetohexamide and its metabolite, hydroxyhexamide in the rat by application of the simultaneous multi-lines fitting technique].
Topics: Acetohexamide; Animals; Injections, Intravenous; Models, Biological; Portal Vein; Rats | 1988 |
Effect of simultaneous administration of drugs on absorption and excretion. XIX. Binding of acetohexamide and its major metabolite, (-)-hydroxyhexamide, to human serum albumin.
Topics: Acetohexamide; Animals; Humans; Kinetics; Male; Protein Binding; Rabbits; Serum Albumin | 1985 |
Enzymatic synthesis of (-)- and (+)-acetoxyhexamides and (-)- and (+)-hydroxyhexamides.
Topics: Acetohexamide; Acetylation; Benzamides; Hydrolysis; Lipase; Pseudomonas; Solvents; Stereoisomerism; Vinyl Compounds | 1999 |
(R)-ACX is a novel sufonylurea compound with potent, quick and short-lasting hypoglycemic activity.
Topics: Acetohexamide; Animals; Blood Glucose; Cell Line; Cricetinae; Dose-Response Relationship, Drug; Glyburide; Hypoglycemic Agents; Insulin; Insulin Secretion; Male; Mice; Mice, Inbred ICR; Rats; Rats, Wistar; Sulfonylurea Compounds | 2000 |
Hypoglycemic effect of S(-)-hydroxyhexamide, a major metabolite of acetohexamide, and its enantiomer R(+)-hydroxyhexamide.
Topics: Acetohexamide; Administration, Oral; Animals; Blood Glucose; Cricetinae; Dose-Response Relationship, Drug; Hypoglycemic Agents; Insulin; Islets of Langerhans; Male; Rabbits; Rats; Rats, Wistar; Stereoisomerism; Time Factors | 2001 |
Sex-dependent pharmacokinetics of S(-)-hydroxyhexamide, a pharmacologically active metabolite of acetohexamide, in rats.
Topics: Acetohexamide; Animals; Female; Male; Rats; Rats, Wistar; Sex Characteristics | 2002 |