hydroxycotinine has been researched along with varenicline in 3 studies
| Studies (hydroxycotinine) | Trials (hydroxycotinine) | Recent Studies (post-2010) (hydroxycotinine) | Studies (varenicline) | Trials (varenicline) | Recent Studies (post-2010) (varenicline) |
|---|---|---|---|---|---|
| 200 | 20 | 99 | 1,597 | 381 | 1,154 |
| Protein | Taxonomy | hydroxycotinine (IC50) | varenicline (IC50) |
|---|---|---|---|
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | 0.2 | |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | 0.2 | |
| Neuronal acetylcholine receptor subunit beta-2 | Homo sapiens (human) | 0.0672 | |
| Neuronal acetylcholine receptor subunit beta-4 | Homo sapiens (human) | 0.11 | |
| Neuronal acetylcholine receptor subunit alpha-3 | Homo sapiens (human) | 0.11 | |
| Neuronal acetylcholine receptor subunit alpha-4 | Homo sapiens (human) | 0.0672 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ansermot, N; Choong, E; Cornuz, J; Dobrinas, M; Eap, CB; Noetzli, M | 1 |
| Benowitz, NL; Cinciripini, P; George, TP; Hawk, LW; Heitjan, DF; Lerman, C; Schnoll, RA; Swan, GE; Tyndale, RF; Wileyto, EP | 1 |
| Cornuz, J; Csajka, C; Dobrinas, M; Eap, CB; Gholamrezaee, M; Glatard, A; Lubomirov, R | 1 |
1 trial(s) available for hydroxycotinine and varenicline
| Article | Year |
|---|---|
Use of the nicotine metabolite ratio as a genetically informed biomarker of response to nicotine patch or varenicline for smoking cessation: a randomised, double-blind placebo-controlled trial.
Topics: Adult; Biomarkers; Cotinine; Female; Humans; Male; Middle Aged; Nicotine; Nicotinic Agonists; Smoking Cessation; Tobacco Use Cessation Devices; Treatment Outcome; Varenicline | 2015 |
2 other study(ies) available for hydroxycotinine and varenicline
| Article | Year |
|---|---|
Quantification of nicotine, cotinine, trans-3'-hydroxycotinine and varenicline in human plasma by a sensitive and specific UPLC-tandem mass-spectrometry procedure for a clinical study on smoking cessation.
Topics: Benzazepines; Chromatography, High Pressure Liquid; Cotinine; Drug Stability; Humans; Linear Models; Nicotine; Quinoxalines; Reproducibility of Results; Sensitivity and Specificity; Smoking Cessation; Tandem Mass Spectrometry; Varenicline | 2011 |
Association of nicotine metabolism and sex with relapse following varenicline and nicotine replacement therapy.
Topics: Adult; Cotinine; Cytochrome P-450 CYP2A6; Female; Genotype; Humans; Longitudinal Studies; Male; Middle Aged; Nicotine; Recurrence; Smoking; Smoking Cessation; Tobacco Products; Varenicline | 2017 |