hydroxycodeinone has been researched along with 6-codeinone* in 1 studies
1 other study(ies) available for hydroxycodeinone and 6-codeinone
| Article | Year |
|---|---|
Transformations of codeine to important semisynthetic opiate derivatives by Pseudomonas putida m10.
A biotransformation mixture which contained codeine and washed cells of Pseudomonas putida M10 gave rise to a number of transformation products that are of clinical importance which included hydrocodone, dihydrocodeine and 14beta-hydroxycodeine. Incubations with the same organism and codeinone gave rise to 14beta-hydroxycodeinone and 14beta-hydroxycodeine. Cell-free extracts and membrane fractions of P. putida M10 were shown to catalyse the 14beta-hydroxylation of codeinone. In addition, the potent analgesic oxycodone was shown to be produced from 14beta-hydroxycodeinone. Topics: Alcohol Oxidoreductases; Chromatography, High Pressure Liquid; Codeine; Culture Media; Magnetic Resonance Spectroscopy; Oxycodone; Pseudomonas putida | 1999 |