hydroxycitric acid has been researched along with methotrexate in 2 studies
| Studies (hydroxycitric acid) | Trials (hydroxycitric acid) | Recent Studies (post-2010) (hydroxycitric acid) | Studies (methotrexate) | Trials (methotrexate) | Recent Studies (post-2010) (methotrexate) |
|---|---|---|---|---|---|
| 204 | 20 | 73 | 41,593 | 5,666 | 11,969 |
| Protein | Taxonomy | hydroxycitric acid (IC50) | methotrexate (IC50) |
|---|---|---|---|
| Thymidylate synthase | Escherichia coli | 1.8 | |
| nuclear receptor coactivator 3 isoform a | Homo sapiens (human) | 0.211 | |
| Toll-like receptor 4 | Homo sapiens (human) | 1.04 | |
| Fatty-acid amide hydrolase 1 | Mus musculus (house mouse) | 0.08 | |
| Dihydrofolate reductase | Homo sapiens (human) | 0.0522 | |
| Dihydrofolate reductase | Mus musculus (house mouse) | 0.0331 | |
| Dihydrofolate reductase | Bos taurus (cattle) | 0.0348 | |
| Dihydrofolate reductase | Gallus gallus (chicken) | 0.0545 | |
| Dihydrofolate reductase | Enterococcus faecium | 0.0014 | |
| Dihydrofolate reductase | Lacticaseibacillus casei | 0.0138 | |
| Thymidylate synthase | Homo sapiens (human) | 0.343 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.0147 | |
| Thymidylate synthase | Escherichia coli K-12 | 0.0181 | |
| Dihydrofolate reductase | Escherichia coli K-12 | 0.1529 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Plasmodium falciparum K1 | 0.084 | |
| Folate receptor beta | Homo sapiens (human) | 0.1585 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.0011 | |
| Cytochrome P450 11B1, mitochondrial | Bos taurus (cattle) | 0.0012 | |
| Folate receptor alpha | Homo sapiens (human) | 0.2263 | |
| Dihydrofolate reductase | Pneumocystis carinii | 0.0717 | |
| Histidine decarboxylase | Rattus norvegicus (Norway rat) | 0.0014 | |
| Trifunctional purine biosynthetic protein adenosine-3 | Homo sapiens (human) | 0.01 | |
| Bifunctional purine biosynthesis protein ATIC | Homo sapiens (human) | 0.01 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.003 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.003 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.003 | |
| Reduced folate transporter | Homo sapiens (human) | 0.012 | |
| Dihydrofolate reductase | Mycobacterium tuberculosis H37Rv | 0.0174 | |
| Folylpolyglutamate synthase, mitochondrial | Homo sapiens (human) | 3.2 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Toxoplasma gondii | 0.0547 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Trypanosoma cruzi | 0.11 | |
| Dihydrofolate reductase | Bacillus anthracis | 0.0136 | |
| Dihydrofolate reductase | Rattus norvegicus (Norway rat) | 0.0047 | |
| Proton-coupled folate transporter | Homo sapiens (human) | 0.1207 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abolhassani, M; Baronzio, G; Behzadi, M; Campion, F; Fiorentini, G; Guais, A; Mainini, C; Montagnani, F; Sanders, E; Schwartz, L | 1 |
| Apetoh, L; Aranda, F; Baracco, EE; Bloy, N; Buque, A; Castoldi, F; Chery, A; Di Virgilio, F; Durand, S; Enot, DP; Falzoni, S; Jacquelot, N; Kroemer, G; Lachkar, S; Levesque, S; Levine, B; Madeo, F; Maiuri, MC; Marino, G; Penninger, JM; Pietrocola, F; Pol, J; Rao, S; Ryffel, B; Senovilla, L; Sica, V; Sigl, V; Vacchelli, E; Yamazaki, T; Zitvogel, L | 1 |
2 other study(ies) available for hydroxycitric acid and methotrexate
| Article | Year |
|---|---|
Adding a combination of hydroxycitrate and lipoic acid (METABLOC™) to chemotherapy improves effectiveness against tumor development: experimental results and case report.
Topics: Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Lewis Lung; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cisplatin; Citrates; Deoxycytidine; Energy Metabolism; Female; Gemcitabine; Humans; Methotrexate; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Pancreatic Neoplasms; Thioctic Acid; Time Factors; Tomography, X-Ray Computed; Treatment Outcome; Urinary Bladder Neoplasms | 2012 |
Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance.
Topics: Animals; Autophagy; Autophagy-Related Protein 5; Caloric Restriction; Cell Line, Tumor; Citrates; Humans; Methotrexate; Mice; Monitoring, Immunologic; Mutation; Neoplasm Transplantation; Neoplasms, Experimental; Proto-Oncogene Proteins p21(ras); Spermidine; T-Lymphocytes, Regulatory | 2016 |